公开(公告)号：US20160251372A1

公开(公告)日：2016-09-01

申请号：US15059142

申请日：2016-03-02

Applicant: SENOMYX, INC.

Inventor： Catherine Tachdjian ,  Xiao Qing Tang ,  Donald S. Karanewsky ,  Guy Servant ,  Xiaodong Li ,  Feng Zhang ,  Qing Chen ,  Hong Zhang ,  Timothy Davis ,  Vincent Darmohusodo ,  Melissa Wong ,  Victor Selchau

IPC: C07D495/04 ,  A61K47/22 ,  A23L2/56 ,  C07D401/12 ,  C07D405/12 ,  C07D215/54 ,  C07D471/04

CPC classification number: C07D495/04 ,  A23L2/56 ,  A23L27/2054 ,  A23L27/88 ,  A23V2002/00 ,  A61K47/22 ,  C07D215/54 ,  C07D215/60 ,  C07D401/12 ,  C07D405/12 ,  C07D471/04 ,  C07D491/048

Abstract: The present invention includes compounds having structural formula (I), or pharmaceutically acceptable salts, solvate, and/or ester thereof. These compounds are useful as sweet flavor modifiers. The present invention also includes compositions comprising the present compounds and methods of enhancing the sweet taste of ingestible compositions. Furthermore, the present invention provides methods for preparing the compounds.

公开(公告)号：US20150265711A1

公开(公告)日：2015-09-24

申请号：US14731224

申请日：2015-06-04

Applicant: SENOMYX, INC.

Inventor： Catherine Tachdjian ,  Xiao Qing Tang ,  Donald S. Karanewsky ,  Guy Servant ,  Xiaodong Li ,  Feng Zhang ,  Qing Chen ,  Hong Zhang ,  Timothy Davis ,  Vincent Darmohusodo ,  Melissa Wong ,  Victor Selchau

IPC: A61K47/22 ,  A23L2/56 ,  A23L1/226

CPC classification number: C07D495/04 ,  A23L2/56 ,  A23L27/2054 ,  A23L27/88 ,  A23V2002/00 ,  A61K47/22 ,  C07D215/54 ,  C07D215/60 ,  C07D401/12 ,  C07D405/12 ,  C07D471/04 ,  C07D491/048

Abstract: The present invention includes compounds having structural formula (I), or pharmaceutically acceptable salts, solvate, and/or ester thereof. These compounds are useful as sweet flavor modifiers. The present invention also includes compositions comprising the present compounds and methods of enhancing the sweet taste of ingestible compositions. Furthermore, the present invention provides methods for preparing the compounds.

Abstract translation: 本发明包括具有结构式（I）的化合物或其药学上可接受的盐，溶剂化物和/或酯。 这些化合物可用作甜味调味剂。 本发明还包括包含本发明化合物的组合物和增强可摄入组合物的甜味的方法。 此外，本发明提供了制备化合物的方法。

公开(公告)号：US09049878B2

公开(公告)日：2015-06-09

申请号：US14061013

申请日：2013-10-23

Applicant: SENOMYX, INC.

Inventor： Catherine Tachdjian ,  Xiao Qing Tang ,  Donald S. Karanewsky ,  Guy Servant ,  Xiaodong Li ,  Feng Zhang ,  Qing Chen ,  Hong Zhang ,  Timothy Davis ,  Vincent Darmohusodo ,  Melissa Wong ,  Victor Selchau

IPC: A23L1/236 ,  A23L1/22 ,  A23L1/226 ,  C07D215/54 ,  C07D215/60 ,  C07D401/12 ,  C07D405/12 ,  C07D471/04 ,  C07D491/048 ,  C07D495/04 ,  A61K47/22

CPC classification number: C07D495/04 ,  A23L2/56 ,  A23L27/2054 ,  A23L27/88 ,  A23V2002/00 ,  A61K47/22 ,  C07D215/54 ,  C07D215/60 ,  C07D401/12 ,  C07D405/12 ,  C07D471/04 ,  C07D491/048

Abstract: The present invention includes compounds having structural formula (I), or pharmaceutically acceptable salts, solvate, and/or ester thereof. These compounds are useful as sweet flavor modifiers. The present invention also includes compositions comprising the present compounds and methods of enhancing the sweet taste of ingestible compositions. Furthermore, the present invention provides methods for preparing the compounds.

Abstract translation: 本发明包括具有结构式（I）的化合物或其药学上可接受的盐，溶剂化物和/或酯。 这些化合物可用作甜味调味剂。 本发明还包括包含本发明化合物的组合物和增强可摄入组合物的甜味的方法。 此外，本发明提供了制备化合物的方法。