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公开(公告)号：US10087154B2
公开(公告)日：2018-10-02
申请号：US15664179
申请日：2017-07-31
Applicant: Senomyx, Inc.
Inventor： Catherine Tachdjian , Donald S. Karanewsky , Xiao-Qing Tang , Qing Chen , Peter Leeming , Tayyab Rashid , Daniel Levin
IPC: C07D285/16 , C07C303/40 , C07C255/57 , C07C253/30 , C07C231/14 , C07C231/02 , C01B21/096 , C07C307/10 , C07C255/59 , C07C255/54 , C07C237/44 , C07C235/20
Abstract: The present invention includes methods/processes and intermediates for preparing compounds having structural Formula (I): wherein X is alkyl, substituted alkyl, alkenyl, substituted alkenyl, heteroalkyl, substituted heteroalkyl, heteroalkenyl, or substituted heteroalkenyl.
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公开(公告)号：US20160251372A1
公开(公告)日：2016-09-01
申请号：US15059142
申请日：2016-03-02
Applicant: SENOMYX, INC.
Inventor： Catherine Tachdjian , Xiao Qing Tang , Donald S. Karanewsky , Guy Servant , Xiaodong Li , Feng Zhang , Qing Chen , Hong Zhang , Timothy Davis , Vincent Darmohusodo , Melissa Wong , Victor Selchau
IPC: C07D495/04 , A61K47/22 , A23L2/56 , C07D401/12 , C07D405/12 , C07D215/54 , C07D471/04
CPC classification number: C07D495/04 , A23L2/56 , A23L27/2054 , A23L27/88 , A23V2002/00 , A61K47/22 , C07D215/54 , C07D215/60 , C07D401/12 , C07D405/12 , C07D471/04 , C07D491/048
Abstract: The present invention includes compounds having structural formula (I), or pharmaceutically acceptable salts, solvate, and/or ester thereof. These compounds are useful as sweet flavor modifiers. The present invention also includes compositions comprising the present compounds and methods of enhancing the sweet taste of ingestible compositions. Furthermore, the present invention provides methods for preparing the compounds.
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公开(公告)号：US20150265711A1
公开(公告)日：2015-09-24
申请号：US14731224
申请日：2015-06-04
Applicant: SENOMYX, INC.
Inventor： Catherine Tachdjian , Xiao Qing Tang , Donald S. Karanewsky , Guy Servant , Xiaodong Li , Feng Zhang , Qing Chen , Hong Zhang , Timothy Davis , Vincent Darmohusodo , Melissa Wong , Victor Selchau
CPC classification number: C07D495/04 , A23L2/56 , A23L27/2054 , A23L27/88 , A23V2002/00 , A61K47/22 , C07D215/54 , C07D215/60 , C07D401/12 , C07D405/12 , C07D471/04 , C07D491/048
Abstract: The present invention includes compounds having structural formula (I), or pharmaceutically acceptable salts, solvate, and/or ester thereof. These compounds are useful as sweet flavor modifiers. The present invention also includes compositions comprising the present compounds and methods of enhancing the sweet taste of ingestible compositions. Furthermore, the present invention provides methods for preparing the compounds.
Abstract translation: 本发明包括具有结构式（I）的化合物或其药学上可接受的盐，溶剂化物和/或酯。 这些化合物可用作甜味调味剂。 本发明还包括包含本发明化合物的组合物和增强可摄入组合物的甜味的方法。 此外，本发明提供了制备化合物的方法。
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公开(公告)号：US20190263762A1
公开(公告)日：2019-08-29
申请号：US16408216
申请日：2019-05-09
Applicant: Senomyx, Inc.
Inventor： Catherine Tachdjian , Donald S. Karanewsky , Xiao-Qing Tang , Qing Chen , Peter Leeming , Tayyab Rashid , Daniel Levin
IPC: C07D285/16 , C07C303/40 , C07C255/57 , C07C253/30 , C07C231/14 , C07C231/02 , C01B21/096 , C07C255/59 , C07C255/54 , C07C237/44 , C07C235/20 , C07C307/10
Abstract: The present invention includes methods/processes and intermediates for preparing compounds having structural Formula (XI): wherein Y is C1-C12 alkylene or C1-C12 alkenylene; and R8 and R12 are independently C1-C12 alkyl.
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公开(公告)号：US20180370931A1
公开(公告)日：2018-12-27
申请号：US16119380
申请日：2018-08-31
Applicant: Senomyx, Inc.
Inventor： Catherine Tachdjian , Donald S. Karanewsky , Xiao-Qing Tang , Qing Chen , Peter Leeming , Tayyab Rashid , Daniel Levin
IPC: C07D285/16 , C07C303/40 , C07C255/57 , C07C253/30 , C07C231/14 , C07C231/02 , C01B21/096 , C07C307/10 , C07C255/59 , C07C255/54 , C07C237/44 , C07C235/20
Abstract: The present invention includes methods/processes and intermediates for preparing compounds having structural Formula (I): wherein X is alkyl, substituted alkyl, alkenyl, substituted alkenyl, heteroalkyl, substituted heteroalkyl, heteroalkenyl, or substituted heteroalkenyl.
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Patent Agency Ranking
公开(公告)号：US09902737B2
公开(公告)日：2018-02-27
申请号：US15059142
申请日：2016-03-02
Applicant: SENOMYX, INC.
Inventor： Catherine Tachdjian , Xiao Qing Tang , Donald S. Karanewsky , Guy Servant , Xiaodong Li , Feng Zhang , Qing Chen , Hong Zhang , Timothy Davis , Vincent Darmohusodo , Melissa S. Wong , Victor Selchau
IPC: C07D495/04 , C07D215/54 , C07D215/60 , C07D401/12 , C07D405/12 , C07D471/04 , C07D491/048 , A61K47/22 , A23L2/56 , A23L27/00 , A23L27/20
CPC classification number: C07D495/04 , A23L2/56 , A23L27/2054 , A23L27/88 , A23V2002/00 , A61K47/22 , C07D215/54 , C07D215/60 , C07D401/12 , C07D405/12 , C07D471/04 , C07D491/048
Abstract: The present invention includes compounds having structural formula (I), or pharmaceutically acceptable salts, solvate, and/or ester thereof. These compounds are useful as sweet flavor modifiers. The present invention also includes compositions comprising the present compounds and methods of enhancing the sweet taste of ingestible compositions. Furthermore, the present invention provides methods for preparing the compounds.
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公开(公告)号：US20160289200A1
公开(公告)日：2016-10-06
申请号：US15184894
申请日：2016-06-16
Applicant: Senomyx, Inc.
Inventor： Catherine Tachdjian , Donald S. Karanewsky , Xiao-Qing Tang , Qing Chen , Peter Leeming , Tayyab Rashid , Daniel Levin
IPC: C07D285/16 , C01B21/096 , C07C303/40 , C07C231/02 , C07C307/10 , C07C253/30
CPC classification number: C07D285/16 , C01B21/096 , C07C231/02 , C07C231/14 , C07C235/20 , C07C237/44 , C07C253/30 , C07C255/54 , C07C255/57 , C07C255/59 , C07C303/40 , C07C307/10
Abstract: The present invention includes methods/processes and intermediates for preparing compounds having structural Formula (I): wherein X is alkyl, substituted alkyl, alkenyl, substituted alkenyl, heteroalkyl, substituted heteroalkyl, heteroalkenyl, or substituted heteroalkenyl.
Abstract translation: 其中X是烷基，取代的烷基，烯基，取代的烯基，杂烷基，取代的杂烷基，杂烯基或取代的杂烯基。
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公开(公告)号：US09382196B2
公开(公告)日：2016-07-05
申请号：US14053897
申请日：2013-10-15
Applicant: SENOMYX, INC.
Inventor： Catherine Tachdjian , Donald S. Karanewsky , Xiao-Qing Tang , Qing Chen , Peter Leeming , Tayyab Rashid , Daniel Levin
IPC: C07C255/57 , C07C255/54 , C07C231/02 , C07C231/04 , C07C231/14 , C07C253/30 , C01B21/096 , C07C235/20 , C07C237/44 , C07C255/59 , C07C307/10 , C07D285/16
CPC classification number: C07D285/16 , C01B21/096 , C07C231/02 , C07C231/14 , C07C235/20 , C07C237/44 , C07C253/30 , C07C255/54 , C07C255/57 , C07C255/59 , C07C303/40 , C07C307/10
Abstract: The present invention includes methods/processes and intermediates for preparing compounds having structural Formula (I): wherein X is alkyl, substituted alkyl, alkenyl, substituted alkenyl, heteroalkyl, substituted heteroalkyl, heteroalkenyl, or substituted heteroalkenyl.
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9.发明申请SUBSTITUTED 4-AMINO-5-(CYCLOHEXYLOXY)QUINOLINE-3-CARBOXYLIC ACIDS AS SWEET FLAVOR MODIFIERS 审中-公开取代的4-氨基-5-（环己基）喹啉-3-羧酸作为甜味剂改性剂公开(公告)号：US20160185727A1
公开(公告)日：2016-06-30
申请号：US14925793
申请日：2015-10-28
Applicant: Senomyx, Inc.
Inventor： Goran Petrovic , Joseph R. Fotsing , Guy Servant , Catherine Tachdjian , Donald Karanewsky , Binh Vong , Brant Clayton Boren , Qing Chen , Hong Zhang , Brett Weylan Ching , Stephanie Lapera
IPC: C07D215/54 , A23L2/60 , A23L2/56 , C07D405/12 , C07D401/12
CPC classification number: C07D215/54 , A23L2/56 , A23L2/60 , A23L27/2054 , A23L27/88 , A23V2002/00 , C07D401/12 , C07D405/12
Abstract: Disclosed herein are 4-amino-5-(cyclohexyloxy)quinoline-3-carboxylic acid compounds having useful as sweet flavor modifiers. Also disclosed herein are ingestible compositions that include one or more of these compounds in combination with a natural or artificial sweetener.
Abstract translation: 本文公开了可用作甜味调味剂的4-氨基-5-（环己氧基）喹啉-3-羧酸化合物。 本文还公开了包含这些化合物中的一种或多种与天然或人造甜味剂组合的可摄入组合物。
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公开(公告)号：US20140107370A1
公开(公告)日：2014-04-17
申请号：US14053897
申请日：2013-10-15
Applicant: SENOMYX, INC.
Inventor： Catherine Tachdjian , Donald S. Karanewsky , Xiao-Qing Tang , Qing Chen , Peter Leeming , Tayyab Rashid , Daniel Levin
IPC: C07C255/57 , C07C253/30 , C07C255/54 , C07C231/02 , C07C231/14
CPC classification number: C07D285/16 , C01B21/096 , C07C231/02 , C07C231/14 , C07C235/20 , C07C237/44 , C07C253/30 , C07C255/54 , C07C255/57 , C07C255/59 , C07C303/40 , C07C307/10
Abstract: The present invention includes methods/processes and intermediates for preparing compounds having structural Formula (I): wherein X is alkyl, substituted alkyl, alkenyl, substituted alkenyl, heteroalkyl, substituted heteroalkyl, heteroalkenyl, or substituted heteroalkenyl.
Abstract translation: 本发明包括用于制备具有结构式（I）的化合物的方法/方法和中间体：其中X是烷基，取代的烷基，烯基，取代的烯基，杂烷基，取代的杂烷基，杂烯基或取代的杂烯基。
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