公开(公告)号：US09527862B2

公开(公告)日：2016-12-27

申请号：US14415857

申请日：2013-01-29

Applicant: SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES

Inventor： Kuiling Ding ,  Xiaoming Wang ,  Zhaobin Han ,  Xubin Wang ,  Zheng Wang

IPC: C07D491/20 ,  C07D493/10 ,  C07D493/20 ,  C07F9/6561 ,  B01J31/22 ,  B01J31/24 ,  C07B53/00 ,  C07F15/00 ,  C07C227/32 ,  C07D495/20

CPC classification number: C07D493/10 ,  B01J31/2247 ,  B01J31/2409 ,  B01J2231/32 ,  B01J2531/0238 ,  B01J2531/0261 ,  B01J2531/824 ,  C07B53/00 ,  C07C227/32 ,  C07D491/20 ,  C07D493/20 ,  C07D495/20 ,  C07F9/6561 ,  C07F9/65616 ,  C07F15/0033 ,  C07C229/34

Abstract: Disclosed are aromatic spiroketal diphosphine ligands, preparation methods and uses thereof. The ligands have the structure of formula (I), in which R1, R2, R3, R4, R5, R6, R7, R8, X and n are defined as such described in the specification. The aromatic spiroketal diphosphine ligands are prepared from aromatic spiroketal compounds. Also disclosed are the preparation methods of aromatic spiroketal compounds. The preparation methods are simple and can produce racemic or chiral aromatic spiroketal diphosphine ligands. The ligands can be used as catalysts of asymmetrical catalytic reactions having economical practicability and industry application prospect

Abstract translation: 公开了芳族螺旋二膦配体，其制备方法和用途。 配体具有式（I）的结构，其中R1，R2，R3，R4，R5，R6，R7，R8，X和n如说明书中所述定义。 芳族螺缩酮二膦配体由芳族螺缩酮化合物制备。 还公开了芳族螺缩酮化合物的制备方法。 制备方法简单，可制备外消旋或手性芳香族螺二酮二膦配体。 该配体可用作具有经济实用性和工业应用前景的不对称催化反应催化剂。

公开(公告)号：US20150252055A1

公开(公告)日：2015-09-10

申请号：US14415857

申请日：2013-01-29

Applicant: SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES

Inventor： Kuiling Ding ,  Xiaoming Wang ,  Zhaobin Han ,  Xubin Wang ,  Zheng Wang

IPC: C07D493/10 ,  C07D495/20 ,  C07D491/20 ,  C07F9/6561

CPC classification number: C07D493/10 ,  B01J31/2247 ,  B01J31/2409 ,  B01J2231/32 ,  B01J2531/0238 ,  B01J2531/0261 ,  B01J2531/824 ,  C07B53/00 ,  C07C227/32 ,  C07D491/20 ,  C07D493/20 ,  C07D495/20 ,  C07F9/6561 ,  C07F9/65616 ,  C07F15/0033 ,  C07C229/34

Abstract: Disclosed are aromatic spiroketal diphosphine ligands, preparation methods and uses thereof. The ligands have the structure of formula (I), in which R1, R2, R3, R4, R5, R6, R7, R8, X and n are defined as such described in the specification. The aromatic spiroketal diphosphine ligands are prepared from aromatic spiroketal compounds. Also disclosed are the preparation methods of aromatic spiroketal compounds. The preparation methods are simple and can produce racemic or chiral aromatic spiroketal diphosphine ligands. The ligands can be used as catalysts of asymmetrical catalytic reactions having economical practicability and industry application prospect.

Abstract translation: 公开了芳族螺旋二膦配体，其制备方法和用途。 配体具有式（I）的结构，其中R1，R2，R3，R4，R5，R6，R7，R8，X和n如说明书中所述定义。 芳族螺缩酮二膦配体由芳族螺缩酮化合物制备。 还公开了芳族螺缩酮化合物的制备方法。 制备方法简单，可制备外消旋或手性芳香族螺二酮二膦配体。 该配体可用作具有经济实用性和工业应用前景的不对称催化反应催化剂。