LIQUID CHROMATOGRAPHY ANALYSIS SYSTEM
    1.
    发明公开

    公开(公告)号:US20230184723A1

    公开(公告)日:2023-06-15

    申请号:US17924996

    申请日:2021-01-08

    Inventor: Shinya IMAMURA

    CPC classification number: G01N30/32 G01N2030/326

    Abstract: An LC system includes a liquid delivery checker configured to execute a liquid delivery check mode of setting a predetermined flow rate to a liquid delivery pump and operating the liquid delivery pump at a timing different from analysis of a sample in order to check a liquid delivery flow rate of the liquid delivery pump, and a measuring instrument for measuring an amount of a mobile phase delivered by the liquid delivery pump during the liquid delivery check mode. The liquid delivery checker is configured to obtain an actual measurement value of a flow rate of a mobile phase when operating the liquid delivery pump by setting the predetermined flow rate to the liquid delivery pump using a measurement value obtained by the measuring instrument in the liquid delivery check mode.

    PLUNGER PUMP
    2.
    发明申请
    PLUNGER PUMP 审中-公开

    公开(公告)号:US20200263686A1

    公开(公告)日:2020-08-20

    申请号:US16762399

    申请日:2017-11-29

    Abstract: Even though a pump head part is finally fixed to a pump body with a fixing member, the pump head part is movable relative to the pump body perpendicular to the axial direction of a plunger at a stage before the pump head part is fixed with the fixing member. In this state, if a plunger driving part is moved to a predetermined location on the front end side of the pump body and the pump head part and the plunger driving part are fitted to each other, the pump head part is positioned where the center axis of the plunger and the center axis of the pump chamber are substantially aligned. By fixing the pump head part to the pump body with the fixing member at this location, it is possible to assemble a plunger pump with the center axis of the plunger and the center axis substantially aligned.

    PRESSURE SENSOR
    3.
    发明公开
    PRESSURE SENSOR 审中-公开

    公开(公告)号:US20240085259A1

    公开(公告)日:2024-03-14

    申请号:US18241674

    申请日:2023-09-01

    CPC classification number: G01L9/0041 G01N30/32 G01N2030/027 G01N2030/326

    Abstract: A sheet-like diaphragm made from a non-metallic material, a main body block made from a non-metallic material, having a diaphragm facing surface facing a main plane of the diaphragm, disposed in a manner that the diaphragm facing surface is covered by the diaphragm, and provided with a fluid outlet and a fluid inlet facing the diaphragm side, a sensor head that has a recess for accommodating pressure transmission liquid, is disposed on a side opposite to the main body block across the diaphragm such that an opening of the recess is closed by the diaphragm, and is configured to detect pressure of fluid flowing between the diaphragm and the diaphragm facing surface by a deformation amount of the diaphragm are included. The fluid inlet and the fluid outlet are provided in a manner separated from the diaphragm further than the diaphragm facing surface.

    LIQUID FEEDING DEVICE
    4.
    发明申请

    公开(公告)号:US20210156376A1

    公开(公告)日:2021-05-27

    申请号:US16612380

    申请日:2017-07-03

    Abstract: A liquid feeding device includes a primary plunger pump; a secondary plunger pump connected downstream; a check valve provided between the primary plunger pump and the secondary plunger pump; a primary pressure sensor that detects a pressure in the pump chamber of the primary plunger pump; a liquid feeding control part configured to control operations of the primary plunger pump and the secondary plunger pump; and a liquid leakage detector configured to detect liquid leakage in the check valve based on a change in an output value of the primary pressure sensor during the waiting time. The liquid feeding control part is configured to control the operation of the primary plunger pump so that a waiting time, where the primary plunger pump stops without operating, is present while a discharge operation by the secondary plunger pump is performed after a suction by the primary plunger pump is completed.

    LIQUID FEEDING DEVICE AND FLUID CHROMATOGRAPH

    公开(公告)号:US20200278329A1

    公开(公告)日:2020-09-03

    申请号:US16648077

    申请日:2017-10-23

    Abstract: The liquid feeding device includes a discharge speed calculation part configured to calculate a discharge speed v of the plunger pump so that a converted value LATM under an atmospheric pressure of a flow rate LPRE of the mobile phase discharged to the discharge channel from the pump part becomes a set flow rate LSET using a volume V of the mobile phase in the pump chamber of the closing pump immediately before the precompression process is started, a volume ΔV reduced due to the precompression process of the mobile phase in the pump chamber of the closing pump, and a feeding pressure P; and a discharge operation controller configured to control a discharge speed of the plunger pump to a discharge speed v calculated by the discharge speed calculation part.

    BACKUP RING AND LIQUID FEEDING PUMP USING BACKUP RING

    公开(公告)号:US20200149636A1

    公开(公告)日:2020-05-14

    申请号:US16183806

    申请日:2018-11-08

    Abstract: A backup ring is for contacting with and supporting a plunger seal which is for sealing a pump chamber provided in a pump head of a plunger type liquid feeding pump. The backup ring includes a maximum outer diameter portion of a cylindrical shape and a smaller outer diameter portion. The maximum outer diameter portion includes a maximum outer diameter in a plunger seal supporting surface side that makes contact with a rear surface of the plunger seal. The smaller outer diameter portion includes a smaller outer diameter than the maximum outer diameter portion in at least one part of a portion other than the maximum outer diameter portion.

    LIQUID CHROMATOGRAPHIC SYSTEM
    7.
    发明申请

    公开(公告)号:US20220146473A1

    公开(公告)日:2022-05-12

    申请号:US17438418

    申请日:2019-03-13

    Abstract: A liquid chromatographic system (1) includes an analysis flow path (12) to which at least one liquid sending pump (14) is connected and through which liquid that is sent by the liquid sending pump (14) flows, a sample injector (4) that injects a sample into the analysis flow path (12), a separation column (6) that is provided on the analysis flow path (12) and is to separate a sample that has been injected into the analysis flow path (12) into components, a detector (8) that is provided on the analysis flow path (12) and is to detect sample components obtained by separation in the separation column (6), a system configuration specifier (26) that specifies a count and a connection structure of the liquid sending pumps (14) connected to the analysis flow path (12) as a system configuration, a condition holder (18) holding a condition that is for detection of a liquid sending failure of the liquid sending pump (14) and is preset in regard to each type of the system configuration, a condition determiner (20) that is configured to determine the condition corresponding to a system configuration specified by the system configuration specifier (26) from among conditions held by the condition holder (18), and a liquid sending failure detector (22) configured to detect a liquid sending failure of the liquid sending pump (14) using the condition determined by the condition determiner (20).

    LIQUID SENDING DEVICE
    8.
    发明申请

    公开(公告)号:US20210172437A1

    公开(公告)日:2021-06-10

    申请号:US16768660

    申请日:2018-06-20

    Abstract: A liquid sending device includes a plunger pump, which performs an intake operation of liquid to and a discharge operation of liquid from a pump chamber and in which pressure in the pump chamber in a case where the intake operation is performed is lower compared to a case where the discharge operation is performed, a check valve that is provided at an inlet port, has a spherical valve element and a valve seat, and passively operates according to the pressure in the pump chamber in such a direction that the valve element is seated on or detached, a pressure sensor that detects the pressure, and an attachment detector that compares the pressure with a preset threshold value and detect attachment of the valve element to the valve seat in a case where the pressure in the pump chamber is equal to or lower than the threshold value.

    LIQUID DELIVERY DEVICE
    10.
    发明申请

    公开(公告)号:US20180245581A1

    公开(公告)日:2018-08-30

    申请号:US15756746

    申请日:2015-12-01

    Inventor: Shinya IMAMURA

    Abstract: A liquid feeding apparatus has a primary side pump and a secondary side pump, and an outlet part of the primary side pump and an inlet part of the secondary side pump are connected to each other via a check valve. A temporary side pump pressure sensor for detecting the pressure inside the pump chamber of the primary side pump and a secondary side pressure sensor for detecting the pressure inside the pump chamber of the secondary side pump are provided. The signal of the primary side pressure sensor and the signal of the secondary side pressure sensor are acquired after the suction operation of the primary side pump is terminated and before the discharge operation of the secondary side pump is terminated.

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