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公开(公告)号：US20220025337A1
公开(公告)日：2022-01-27
申请号：US17298446
申请日：2019-11-29
Applicant: Shiseido Company, Ltd.
Inventor： Shoko YAMADA , Sayaka KOIDE , Masaya TAKAGI , Tsutomu SOMA , Kenta FUKUMURA
Abstract: The present invention provides a pigmentation skin model that comprises: a first cell group containing fibroblasts damaged by light irradiation, said first cell group being seeded on a first cell culture substratum; and a second cell group containing melanocytes and keratinocytes, said second cell group being applied onto the first cell group. The present invention also provides a method for producing the pigmentation skin model, and a method for evaluating a factor for treating or preventing pigmentation of the skin, said method comprising using the pigmentation skin model.
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Patent Agency Ranking
公开(公告)号：US20230364006A1
公开(公告)日：2023-11-16
申请号：US18225377
申请日：2023-07-24
Applicant: Shiseido Company, Ltd.
Inventor： Sayaka KOIDE , Masaya TAKAGI , Shoko YAMADA , Ritsuro IDETA , Takashi SATOH
Abstract: The present invention provides a composition for treating or preventing skin pigmentation, which contains fibroblasts as an active ingredient, wherein the fibroblasts are those fibroblasts which are less damaged than fibroblasts localized in a site where the skin pigmentation occurs, and the composition is characterized by being intended to be applied to a site where the pigmentation occurs or a dermis tissue around the site.
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公开(公告)号：US20220023197A1
公开(公告)日：2022-01-27
申请号：US17298440
申请日：2019-11-29
Applicant: Shiseido Company, Ltd.
Inventor： Sayaka KOIDE , Masaya TAKAGI , Shoko YAMADA , Ritsuro IDETA , Takashi SATOH
Abstract: The present invention provides a composition for treating or preventing skin pigmentation, which contains fibroblasts as an active ingredient, wherein the fibroblasts are those fibroblasts which are less damaged than fibroblasts localized in a site where the skin pigmentation occurs, and the composition is characterized by being intended to be applied to a site where the pigmentation occurs or a dermis tissue around the site.
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公开(公告)号：US20230172837A1
公开(公告)日：2023-06-08
申请号：US17919954
申请日：2021-04-19
Applicant: SHISEIDO COMPANY, LTD.
Inventor： Satoshi HORIBA , Junichi HOSOI , Daigo INOUE , Kentaro KAJIYA , Masaya TAKAGI , Yuko MATSUURA , Masato IINO
IPC: A61K8/9761 , A61Q19/02 , A61Q19/08 , A45D44/22
CPC classification number: A61K8/9761 , A61Q19/02 , A61Q19/08 , A45D44/22
Abstract: The present invention provides an agent for preventing and/or improving photoaging and/or dermal pigmentation comprising Thujae Semen extract as an active ingredient. The present invention also provides a cosmetic method which includes a step for applying the agent for preventing and/or improving photoaging and/or dermal pigmentation to skin to be treated, and a cosmetic device to be applied in said method.
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公开(公告)号：US20210179905A1
公开(公告)日：2021-06-17
申请号：US17055310
申请日：2019-05-14
Applicant: Shiseido Company, Ltd.
Inventor： Chika TANAKA , Tomoko ONODERA , Masaya TAKAGI , Chieko MIZUMOTO , Daisuke KUBOTA , Masahiko YANO
Abstract: A stratum corneum-collecting adhesive composition includes a hydrophobic component having adhesiveness, and a hydrophilic component that is present in a dispersed state in the hydrophobic component.
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公开(公告)号：US20190079080A1
公开(公告)日：2019-03-14
申请号：US16136929
申请日：2018-09-20
Applicant: Shiseido Company, Ltd.
Inventor： Toshihiko HIBINO , Mami YAMAMOTO , Masaya TAKAGI , Junichi SAKABE , Yoshiki TOKURA
Abstract: The present invention provides an antibody specific to a C-terminal domain of a human profilaggrin gene, wherein the C-terminal domain is a peptide comprising the amino acid sequence set forth in SEQ ID NO:1 or a variant thereof, a method for detecting a filaggrin gene mutation using the antibody, and a kit for the detection.
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