公开(公告)号：US10130564B2

公开(公告)日：2018-11-20

申请号：US15300696

申请日：2015-03-31

Applicant: MITSUI CHEMICALS, INC. ,  SHOFU INC. ,  SUN MEDICAL CO., LTD.

Inventor： Kazuhiko Yoshinaga ,  Hiroshi Naruse ,  Mitsuji Teramae ,  Kiyomi Fuchigami ,  Hidefumi Fujimura ,  Masuji Tsuchikawa ,  Hirofumi Imai

IPC: A61K6/083 ,  C07C271/20 ,  A61K6/00

Abstract: Provided are dental polymerizable monomers that can give cured products having high toughness and high rigidity, dental polymerizable monomer compositions containing the polymerizable monomers, and dental compositions containing the dental polymerizable monomer compositions, and cured products thereof having high mechanical properties. The dental polymerizable monomer (A) which includes a urethane acrylate obtained from an appropriately rigid diisocyanate and an appropriately flexible hydroxyacrylate is used to prepare a dental polymerizable monomer composition containing the dental polymerizable monomer, and a dental composition containing the dental polymerizable monomer composition.

公开(公告)号：US11559471B2

公开(公告)日：2023-01-24

申请号：US16059446

申请日：2018-08-09

Applicant: SHOFU INC.

Inventor： Daisuke Hara ,  Yuji Sadakane ,  Katsura Ishikawa ,  Hidefumi Fujimura ,  Shuji Sakamoto ,  Akihiro Nagafuji ,  Toshiyuki Nakatsuka

IPC: A61K6/00 ,  A61K8/26 ,  A61Q11/00 ,  A61K8/21 ,  A61K8/19 ,  A61K8/25 ,  A61K8/81 ,  C08L33/06 ,  A61K6/70 ,  A61K6/20 ,  A61K6/77

Abstract: To provide a dental composition wherein the acid buffering capacity can be attained and the acid resistance of the tooth substance can be improved while maintaining very high foul breath inhibition capacity. A dental composition including: ion sustained-release glass; and a carrier for supporting the ion sustained-release glass, wherein the ion sustained-release glass is fluoroaluminoborosilicate glass having a composition range of: 15% to 35% by mass SiO2; 15% to 30% by mass Al2O3; 5% to 20% by mass B2O3; 20% to 45% by mass SrO; 5% to 15% by mass F; and 0% to 10% by mass Na2O.

公开(公告)号：US11744781B2

公开(公告)日：2023-09-05

申请号：US17001853

申请日：2020-08-25

Applicant: SHOFU INC.

Inventor： Mamoru Hosokawa ,  Hidefumi Fujimura

IPC: A61K6/887 ,  B33Y80/00 ,  A61K6/76 ,  A61K6/62 ,  B33Y70/10 ,  A61K6/17

CPC classification number: A61K6/887 ,  A61K6/17 ,  A61K6/62 ,  A61K6/76 ,  B33Y70/10 ,  B33Y80/00

Abstract: To provide a dental photopolymerizable composition which can prepare a dental restoration with excellent aesthetic and mechanical properties by optical three-dimensional modeling method (stereolithography). The dental photopolymerizable composition for 3D printer of the present invention comprises: a (a) (meth)acrylate-based polymerizable monomer consisting of a (a1) (meth)acrylate-based polymerizable monomer containing a urethane structure and a (a2) (meth)acrylate-based polymerizable monomer not containing a urethane structure, a (b) cohesive inorganic filler, and a (c) photopolymerization initiator, wherein; a ratio of the (a1) (meth)acrylate-based polymerizable monomer containing a urethane structure and the (a2) (meth)acrylate-based polymerizable monomer not containing a urethane structure in the (a) (meth)acrylate-based polymerizable monomer is 51 to 80: 49 to 20 pts.wt., a ratio of the (a) (meth)acrylate-based polymerizable monomer and the (b) cohesive inorganic filler is 50 to 91: 50 to 9 pts.wt., and the dental photopolymerizable composition for 3D printer contains 0.1 to 5 pts.wt. of the (c) photopolymerization initiator based on 100 pts.wt. of the (a) (meth)acrylate-based polymerizable monomer.

公开(公告)号：US11759299B2

公开(公告)日：2023-09-19

申请号：US16829212

申请日：2020-03-25

Applicant: SHOFU INC.

Inventor： Namiki Niwa ,  Hidefumi Fujimura

IPC: A61C13/00 ,  C08F2/50 ,  C08F20/16 ,  C08F20/20 ,  C08F22/12 ,  B33Y10/00 ,  B33Y70/00 ,  B33Y80/00 ,  B33Y40/20

CPC classification number: A61C13/0019 ,  A61C13/0013 ,  C08F2/50 ,  C08F20/16 ,  C08F20/20 ,  C08F22/12 ,  B33Y10/00 ,  B33Y40/20 ,  B33Y70/00 ,  B33Y80/00

Abstract: To provide a dental stereolithography-type three-dimensional printing material in which the total preparing time required from modeling with using a 3D printer to a final curing is short, work efficiency is excellent, temporal shrinkage deformation of a dental three-dimensional modeled object is suppressed and a dimensional accuracy is excellent. The dental stereolithography-type three-dimensional printing material of the present invention comprises at least one or more (a) monofunctional acrylate monomer having an aromatic ring and (b) photopolymerization initiator, wherein an electronegativity difference between adjacent atoms which are bonded by covalent bond in all atoms constituting the (a) monofunctional acrylate monomer having an aromatic ring is less than 1.0.

公开(公告)号：US11648184B2

公开(公告)日：2023-05-16

申请号：US14593103

申请日：2015-01-09

Applicant: SHOFU INC.

Inventor： Daisuke Hara ,  Yuji Sadakane ,  Katsura Ishikawa ,  Hidefumi Fujimura ,  Shuji Sakamoto ,  Akihiro Nagafuji ,  Toshiyuki Nakatsuka

IPC: A61K6/00 ,  A61Q11/00 ,  A61K8/19 ,  A61K8/21 ,  A61K8/25 ,  A61K8/26 ,  A61K6/70 ,  A61K8/81 ,  A61K6/20 ,  A61K6/77

CPC classification number: A61K6/70 ,  A61K6/20 ,  A61K6/77 ,  A61K8/19 ,  A61K8/21 ,  A61K8/25 ,  A61K8/26 ,  A61K8/8152 ,  A61Q11/00 ,  A61K2800/56 ,  A61K2800/81 ,  A61K2800/882 ,  A61K2800/95 ,  A61K6/20 ,  C08L33/06

Abstract: To provide a dental composition wherein the acid buffering capacity can be attained and the acid resistance of the tooth substance can be improved while maintaining very high foul breath inhibition capacity. A dental composition including: ion sustained-release glass; and a carrier for supporting the ion sustained-release glass, wherein the ion sustained-release glass is fluoroaluminoborosilicate glass having a composition range of: 15% to 35% by mass SiO2; 15% to 30% by mass Al2O3; 5% to 20% by mass B2O3; 20% to 45% by mass SrO; 5% to 15% by mass F; and 0% to 10% by mass Na2O.

公开(公告)号：US11033465B2

公开(公告)日：2021-06-15

申请号：US16357377

申请日：2019-03-19

Applicant: SHOFU INC.

Inventor： Shunsuke Miyata ,  Hidefumi Fujimura

IPC: A61K6/30 ,  A61K6/71 ,  A61K6/62

Abstract: To provide a one paste type dental adhesive composition which has mechanical characteristics and aesthetic property required in the restoration material, is superior in durable adhesive strength to the tooth substance, and is hard to be affected by the polymerization shrinkage stress and exhibits excellent durable adhesive strength even if the composition of the present invention is collectively filled and cured.
To provide a dental adhesive composition comprising: (a) an acidic group-non-containing polymerizable monomer, (b) an acidic group-containing polymerizable monomer, (c) a filler, (d) a photo polymerization initiator, and (e) a chain transfer agent, wherein the chain transfer agent (e) contains α-alkylstyrene compound.

公开(公告)号：US10130563B2

公开(公告)日：2018-11-20

申请号：US15300669

申请日：2015-03-31

Applicant: MITSUI CHEMICALS, INC. ,  SHOFU INC. ,  SUN MEDICAL CO., LTD.

Inventor： Kazuhiko Yoshinaga ,  Hiroshi Naruse ,  Mitsuji Teramae ,  Kiyomi Fuchigami ,  Hidefumi Fujimura ,  Masuji Tsuchikawa ,  Hirofumi Imai

IPC: A61K6/083 ,  A61K6/00 ,  C07C271/20

Abstract: Provided are dental polymerizable monomer compositions that can give cured products having high toughness and high rigidity, and dental compositions containing such dental polymerizable monomer compositions and cured products thereof having high mechanical properties. The dental polymerizable monomer composition includes a urethane acrylate compound (A) and a polymerizable compound (B) having at least one polymerizable group selected from methacryloyl groups and acryloyl groups, the urethane acrylate compound (A) being obtained by reacting a specific hydroxyacrylate (a1) with a diisocyanate (a2) having two isocyanate groups bonded to a divalent C6-9 aromatic hydrocarbon group or a divalent C6-9 bridged cyclic hydrocarbon group via a methylene group optionally substituted with a hydrocarbon group in place of a hydrogen atom, the proportion of the number of acryloyl groups present in the urethane acrylate compound (A) being 10% to less than 90% relative to the total number of (meth)acryloyl groups in the monomer composition.