公开(公告)号：US10661037B2

公开(公告)日：2020-05-26

申请号：US15023290

申请日：2014-06-25

Applicant: SOCPRA SCIENCES ET GENIE S.E.C.

Inventor： Mathieu Nadeau ,  Philippe Micheau ,  Raymond Robert ,  Herve Walti ,  Olivier Avoine ,  Jean-Paul Praud

IPC: A61M16/00 ,  A61M16/04 ,  A61B5/01 ,  A61B5/087 ,  A61B5/08 ,  A61M16/08 ,  A61M16/14 ,  A61M16/10 ,  A61F7/12 ,  A61F7/00

Abstract: A method, connector and system for obtaining an indirect measurement of a parameter in a patient with a total liquid ventilation (TLV) system. At least one parameter measurement is obtained of a liquid taken in the TLV system comprising an endotracheal tube having a distal end inserted in a patient's trachea. At least one flow measurement is obtained of a liquid taken in the TLV system. Considering a fluid model of the TLV system, the at least one parameter measurement and the least one flow measurement are processed into the indirect measurement of the parameter in the patient. The indirect measurement may be a temperature or pressure. The temperature can be a lung temperature, a blood temperature or an organ temperature. The pressure may be a tracheal pressure or an alveolar pressure.

公开(公告)号：US12083271B2

公开(公告)日：2024-09-10

申请号：US17048263

申请日：2019-04-12

Applicant: SOCPRA SCIENCES ET GENIE S.E.C. ,  ECOLE NATIONALE VETERINAIRE D'ALFORT ,  INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE ,  UNIVERSITE PARIS EST CRETEIL VAL DE MARNE

Inventor： Philippe Micheau ,  Renaud Tissier ,  Matthias Kohlhauer ,  Julien Mousseau ,  Mathieu Nadeau ,  Jonathan Vandamme

IPC: A61M16/00 ,  A61F7/00 ,  A61F7/12 ,  A61M16/08 ,  A61M16/10 ,  A61M16/20

CPC classification number: A61M16/0054 ,  A61F7/0085 ,  A61F7/12 ,  A61M16/0003 ,  A61M16/024 ,  A61M16/1005 ,  A61M16/1075 ,  A61F2007/0064 ,  A61F2007/0086 ,  A61F2007/126 ,  A61M2016/0027 ,  A61M2016/0036 ,  A61M16/0051 ,  A61M16/0833 ,  A61M16/208 ,  A61M2202/02 ,  A61M2202/0476 ,  A61M2205/3368 ,  A61M2205/3606 ,  A61M2205/366 ,  A61M2230/46

Abstract: Liquid ventilator and methods integrating the concept of total liquid ventilation (TLV) using liquid volumes below functional residual capacity (FRC) of mammal's lungs are disclosed. Beyond the automatization of the whole process, the technology has been up-scaled to confirm that TLV at residual volumes below FRC can provide a safe procedure while enabling the full potential of TLV in a mammal such as humans or adult-sized animals. Such tidal liquid ventilation strongly differs from the previously known TLV approach, opening promising perspectives for a safer clinical translation. Also disclosed are apparatus and method for safe and fast induction of hypothermia during liquid ventilation of a mammal.