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1.发明申请公开(公告)号：US20230053597A1
公开(公告)日：2023-02-23
申请号：US17982094
申请日：2022-11-07
摘要： To provide a technology of optimizing a suction condition of a microparticle.
The present technology provides an optimizing method of a suction condition of a microparticle including: a particle number counting step of detecting a time point when a microparticle passes through a predetermined position on a main flow path through which liquid containing the microparticle flows, sucking the microparticle from the main flow path to a microparticle suction flow path by the microparticle suction flow path with a predetermined suction force, and counting the number of microparticles sucked into the microparticle suction flow path; and a step of determining an elapsed time from passage through the predetermined position with which the suction by the microparticle suction flow path should be performed on the basis of a time from the time point when the microparticle passes through the predetermined position on the main flow path until the suction is performed and the number of counted microparticles.-
公开(公告)号：US11305318B2
公开(公告)日：2022-04-19
申请号：US17240390
申请日：2021-04-26
发明人： Tatsumi Ito
摘要： A particle sorting apparatus is provided. The particle sorting apparatus includes a first detector of a first scatter channel to detect a first light scatter generated by a particle flowing in a flow channel of a fluid sample and passing through a first laser beam, and a second detector of a second scatter channel to detect a second light scatter generated by the particle flowing in the flow channel of the fluid sample and passing through a second laser beam. The particle sorting apparatus also includes circuitry configured to output a first scatter pulse information and a first detection time of the first light scatter channel, a second scatter pulse information and a second detection time of the second light scatter channel. The first laser beam and the second laser beam are irradiated to the particle in different positions of the flow channel.
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公开(公告)号：US20240142369A1
公开(公告)日：2024-05-02
申请号：US18278067
申请日：2022-02-22
发明人： Taiki Uno , Tatsumi Ito
CPC分类号： G01N15/1484 , B01L3/502761 , G01N2015/1028
摘要： There is provided a particle sorting kit including a filter unit, which has a small amount of particle loss at a connection portion between a tube through which a sample liquid flows and the filter unit and functions even at a low flow rate.
There is provided a particle sorting kit including a sample accommodation unit for accommodating a sample liquid containing particles, a sample flow path through which the sample liquid flows, a detection region in which a target particle is detected from the sample liquid, and a filter unit including a filter and a fitting portion that fits to an outer diameter of a tube for connection with the sample accommodation unit and/or the sample flow path, in which the fitting portion includes a protrusion that protrudes in the tube direction.-
公开(公告)号：US20220412870A1
公开(公告)日：2022-12-29
申请号：US17776983
申请日：2020-11-13
发明人： Naohisa Sakamoto , Tatsumi Ito , Shinji Tashiro , Nobuhiko Nishiki , Naohide Miyamoto , Kentaro Kuriyama , Kazuya Takahashi , Yoichi Katsumoto , Atsushi Nakamura
IPC分类号： G01N15/14
摘要： To provide a microchip that is easily handled.
Provided is a microchip having a plate shape and including: a sample liquid inlet into which a sample liquid is introduced; a main flow path through which the sample liquid introduced from the sample liquid inlet flows; and a sorting flow path into which a target sample is sorted from the sample liquid, in which the sample liquid inlet and a terminal end of the sorting flow path are formed on a same side surface. Furthermore, a sample sorting kit including the microchip is also provided. Moreover, a microparticle sorting device on which the microchip is mounted is also provided.-
公开(公告)号：US20220396757A1
公开(公告)日：2022-12-15
申请号：US17771418
申请日：2020-07-20
发明人： Masahiro Matsumoto , Tatsumi Ito
摘要： Provided is a new method for more efficiently generating emulsion particles each containing one fine particle.
The present technology provides a method of collecting fine particles, in which in a fine particle sorting mechanism having a channel structure including a main channel through which the fine particles flow, a collection channel into which particles to be collected are collected from among the fine particles, a connection channel that connects the main channel and the collection channel, and a liquid supply channel connected to the connection channel so as to supply a liquid, the method includes: a flow step of causing a first liquid containing the fine particles to flow through the main channel; a determination step of determining whether or not the fine particles flowing through the main channel are the particles to be collected; and a collection step of collecting the particles to be collected into the collection channel, and, in the collection step, the particles to be collected are collected into a second liquid that is immiscible with the first liquid in the collection channel while being contained in the first liquid.-
公开(公告)号：US11666946B2
公开(公告)日：2023-06-06
申请号：US17469335
申请日：2021-09-08
发明人： Tatsumi Ito
CPC分类号： B07C5/3416 , B01L3/502776 , B07C5/342 , F16K99/0001 , G01N15/1459 , G01N15/1484 , B01L3/502761 , B01L2200/0652 , B01L2300/0816 , B01L2300/0819 , B01L2300/0861 , B01L2400/0487 , F16K99/0028 , G01N2015/1006 , G01N2015/149
摘要： There is provided a microparticle sorting method including a procedure of collecting a microparticle in a fluid that flows through a main channel in a branch channel that is in communication with the main channel by generating a negative pressure in the branch channel. In the procedure, a flow of a fluid is formed that flows toward a side of the main channel from a side of the branch channel at a communication opening between the main channel and the branch channel.
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7.发明授权公开(公告)号：US11927524B2
公开(公告)日：2024-03-12
申请号：US17982094
申请日：2022-11-07
CPC分类号： G01N15/1484 , B01L3/502761 , G01N15/1436 , B01L2200/0652 , G01N2015/149
摘要： To provide a technology of optimizing a suction condition of a microparticle.
The present technology provides
an optimizing method of a suction condition of a microparticle including:
a particle number counting step of detecting a time point when a microparticle passes through a predetermined position on a main flow path through which liquid containing the microparticle flows, sucking the microparticle from the main flow path to a microparticle suction flow path by the microparticle suction flow path with a predetermined suction force, and counting the number of microparticles sucked into the microparticle suction flow path; and a step of determining an elapsed time from passage through the predetermined position with which the suction by the microparticle suction flow path should be performed
on the basis of a time from the time point when the microparticle passes through the predetermined position on the main flow path until the suction is performed and the number of counted microparticles.
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