公开(公告)号：US09186249B2

公开(公告)日：2015-11-17

申请号：US13962789

申请日：2013-08-08

Applicant: Sorin Group Italia S.r.l.

Inventor： Giovanni Rolando ,  Paolo Gaschino ,  Laura Ghione ,  Andrea Marchisio ,  Monica Achiluzzi

IPC: A61F2/24

CPC classification number: A61F2/2412 ,  A61F2/2418 ,  A61F2/2436 ,  A61F2220/0075

Abstract: Described is a valve prosthesis comprising: an annular structure, and a plurality of valve leaflets, and a plurality of anchoring members attached around the annular structure, the anchoring members including: a web portion coupled to the annular structure and extending axially thereto, and two end portions at axially opposed sides of the web portion, the end portions having: an insertion condition for insertion of the prosthesis, wherein the end portions are aligned to the web portion and extend axially with respect to the annular structure; and an anchoring condition for anchoring the prosthesis, wherein the end portions extend at an angle to the web portion radially outwardly of the annular structure to provide anchoring of the prosthesis proximally and distally, respectively, of the annulus, and wherein one end portion forms an obtuse angle with the web portion.

Abstract translation: 描述了一种阀门假体，其包括：环形结构，以及多个瓣叶，以及围绕环形结构附接的多个锚固构件，所述锚定构件包括：腹板部分，其联接到所述环形结构并且轴向延伸， 所述端部具有用于插入所述假体的插入状态，其中所述端部与所述腹板部分对准并且相对于所述环形结构轴向延伸; 以及用于锚定假体的锚固条件，其中端部部分以与环形结构的径向外侧的腹板部分成一定角度延伸，以分别使瓣膜近端和远端锚固假体，并且其中一个端部形成 与网部分呈钝角。

公开(公告)号：US20140046434A1

公开(公告)日：2014-02-13

申请号：US13962789

申请日：2013-08-08

Applicant: Sorin Group Italia S.r.l.

Inventor： Giovanni Rolando ,  Paolo Gaschino ,  Laura Ghione ,  Andrea Marchisio ,  Monica Achiluzzi

IPC: A61F2/24

CPC classification number: A61F2/2412 ,  A61F2/2418 ,  A61F2/2436 ,  A61F2220/0075

Abstract: Described is a valve prosthesis comprising: an annular structure, and a plurality of valve leaflets, and a plurality of anchoring members attached around the annular structure, the anchoring members including: a web portion coupled to the annular structure and extending axially thereto, and two end portions at axially opposed sides of the web portion, the end portions having: an insertion condition for insertion of the prosthesis, wherein the end portions are aligned to the web portion and extend axially with respect to the annular structure; and an anchoring condition for anchoring the prosthesis, wherein the end portions extend at an angle to the web portion radially outwardly of the annular structure to provide anchoring of the prosthesis proximally and distally, respectively, of the annulus, and wherein one end portion forms an obtuse angle with the web portion.

Abstract translation: 描述了一种阀门假体，其包括：环形结构，以及多个瓣叶，以及围绕环形结构附接的多个锚固构件，所述锚定构件包括：腹板部分，其联接到所述环形结构并且轴向延伸， 所述端部具有用于插入所述假体的插入状态，其中所述端部与所述腹板部分对准并且相对于所述环形结构轴向延伸; 以及用于锚定假体的锚固条件，其中端部部分以与环形结构的径向外侧的腹板部分成一定角度延伸，以分别使瓣膜近端和远端锚固假体，并且其中一个端部形成 与网部分呈钝角。

公开(公告)号：US09895225B2

公开(公告)日：2018-02-20

申请号：US13835508

申请日：2013-03-15

Applicant: Sorin Group Italia S.r.l.

Inventor： Giovanni Rolando ,  Paolo Gaschino ,  Antonella Orecchia ,  Monica Achiluzzi ,  Massimiliano Ares

IPC: A61F2/24

CPC classification number: A61F2/2445 ,  A61F2/2409 ,  A61F2/2418 ,  A61F2/2433 ,  A61F2/2436 ,  A61F2220/0016 ,  A61F2230/005 ,  A61F2230/0054 ,  A61F2230/0067 ,  A61F2230/0078 ,  A61F2230/008 ,  A61F2250/0029 ,  A61F2250/0048

Abstract: A collapsible valve prosthesis includes an armature and a set of prosthetic valve leaflets supported by the armature. The armature is expandable from a contracted condition to an expanded condition for anchoring at an annulus of a natural valve site, and includes a tubular intra-annular portion defining a blood flow lumen having an inflow side and an outflow side. The tubular intra-annular portion supports the prosthetic valve leaflets in the blood flow lumen and is provided with outward formations for coupling with the natural valve site. The armature includes an over-annular portion linked to the intra-annular portion to extend collar-like over the annulus of the natural valve site at the inflow side of the blood flow lumen. The armature may also include an under-annular portion to extend collar-like at the outflow side of the blood flow lumen. The prosthesis may permit mitral valve replacement (MVR) without removing the native valve leaflets and the chordae tendineae.

公开(公告)号：US08685084B2

公开(公告)日：2014-04-01

申请号：US13729636

申请日：2012-12-28

Applicant: Sorin Group Italia S.r.l.

Inventor： Giovanni Rolando ,  Paolo Gaschino ,  Monica Achiluzzi ,  Felice Giuseppe Carlino

IPC: A61F2/24

CPC classification number: A61F2/243 ,  A61F2/06 ,  A61F2/064 ,  A61F2/2409 ,  A61F2/2427 ,  A61F2/2436 ,  A61F2002/9522 ,  Y10T29/49412

Abstract: A kit for implanting a prosthetic vascular conduit includes a prosthetic vascular conduit for coupling to a prosthetic valve having an annular portion. The conduit includes a terminal collar member for receiving the valve. The kit further includes a holder including a shaft and a hub including a receiving portion configured for housing a prosthetic valve. The conduit is fitted on the holder so that at least a portion of the conduit wraps over the receiving portion of the hub. A sleeve member fitted onto the conduit in a position corresponding to the receiving portion of the hub, and a portion of the collar member is wrapped or folded over the sleeve member. The sleeve member is slidable away from the hub to unwrap the collar member such that it is disposed around the annular portion of a prosthetic valve.

Abstract translation: 用于植入假体血管导管的套件包括用于联接到具有环形部分的假体瓣膜的假体血管导管。 导管包括用于接收阀的端子套环构件。 套件还包括保持器，其包括轴和毂，包括构造成容纳人造瓣膜的接收部分。 导管安装在保持器上，使得至少一部分导管缠绕在毂的接收部分上。 套筒构件在对应于轮毂的接收部分的位置中安装到导管上，并且套环构件的一部分被卷绕或折叠在套筒构件上。 套筒构件可以从轮毂滑动以展开套环构件，使得其围绕假肢瓣膜的环形部分设置。

公开(公告)号：US20150374495A1

公开(公告)日：2015-12-31

申请号：US14846853

申请日：2015-09-07

Applicant: Sorin Group Italia S.r.l.

Inventor： Xavier Ruyra Baliarda ,  Monica Achiluzzi ,  Laura Ghione

IPC: A61F2/24

CPC classification number: A61F2/2457 ,  A61F2/2412 ,  A61F2/2445 ,  A61F2/2448 ,  A61F2/2466

Abstract: Described is a prosthetic device and methods for repairing a mitral valve having an annulus, leaflets, and chordae tendinae. The device comprises an elongate band including a plurality of reference elements that are located along the elongate band and protrude inwardly with respect thereto towards a center of the annulus, the plurality of reference elements being adapted to receive a corresponding plurality of artificial cords that are tied onto the reference elements and the plurality of reference elements adapted to be cut or removed in order to release the tied artificial cords.

Abstract translation: 描述了一种修复装置和修复具有环状，小叶和腱索的二尖瓣的方法。 该装置包括细长带，其包括沿着细长带定位并相对于其朝向环的中心向内突出的多个参考元件，多个参考元件适于接收相应的多个被连接的人造绳 到参考元件和适于被切割或移除的多个参考元件以便释放被连接的人造绳。

公开(公告)号：US09138314B2

公开(公告)日：2015-09-22

申请号：US14176533

申请日：2014-02-10

Applicant: Sorin Group Italia S.r.l.

Inventor： Giovanni Rolando ,  Paolo Gaschino ,  Monica Achiluzzi ,  Felice Giuseppe Carlino

IPC: A61F2/24 ,  A61F2/06 ,  A61F2/95

CPC classification number: A61F2/243 ,  A61F2/06 ,  A61F2/064 ,  A61F2/2409 ,  A61F2/2427 ,  A61F2/2436 ,  A61F2002/9522 ,  Y10T29/49412

Abstract: A kit for implanting a prosthetic vascular conduit includes a prosthetic vascular conduit for coupling to a prosthetic valve having an annular portion. The conduit includes a terminal collar member for receiving the valve. The kit further includes a holder including a shaft and a hub including a receiving portion configured for housing a prosthetic valve. The conduit is fitted on the holder so that at least a portion of the conduit wraps over the receiving portion of the hub. A sleeve member fitted onto the conduit in a position corresponding to the receiving portion of the hub, and a portion of the collar member is wrapped or folded over the sleeve member. The sleeve member is slidable away from the hub to unwrap the collar member such that it is disposed around the annular portion of a prosthetic valve.

Abstract translation: 用于植入假体血管导管的套件包括用于联接到具有环形部分的假体瓣膜的假体血管导管。 导管包括用于接收阀的端子套环构件。 套件还包括保持器，其包括轴和毂，包括构造成容纳人造瓣膜的接收部分。 导管安装在保持器上，使得至少一部分导管缠绕在毂的接收部分上。 套筒构件在对应于轮毂的接收部分的位置中安装到导管上，并且套环构件的一部分被卷绕或折叠在套筒构件上。 套筒构件可以从轮毂滑动以展开套环构件，使得其围绕假肢瓣膜的环形部分设置。

公开(公告)号：US09700413B2

公开(公告)日：2017-07-11

申请号：US14846853

申请日：2015-09-07

Applicant: Sorin Group Italia S.r.l.

Inventor： Xavier Ruyra Baliarda ,  Monica Achiluzzi ,  Laura Ghione

IPC: A61F2/24

CPC classification number: A61F2/2457 ,  A61F2/2412 ,  A61F2/2445 ,  A61F2/2448 ,  A61F2/2466

Abstract: Described is a prosthetic device and methods for repairing a mitral valve having an annulus, leaflets, and chordae tendinae. The device comprises an elongate band including a plurality of reference elements that are located along the elongate band and protrude inwardly with respect thereto towards a center of the annulus, the plurality of reference elements being adapted to receive a corresponding plurality of artificial cords that are tied onto the reference elements and the plurality of reference elements adapted to be cut or removed in order to release the tied artificial cords.

公开(公告)号：US20130253643A1

公开(公告)日：2013-09-26

申请号：US13835508

申请日：2013-03-15

Applicant: SORIN GROUP ITALIA S.R.L.

Inventor： Giovanni Rolando ,  Paolo Gaschino ,  Antonella Orecchia ,  Monica Achiluzzi ,  Massimiliano Ares

IPC: A61F2/24

CPC classification number: A61F2/2445 ,  A61F2/2409 ,  A61F2/2418 ,  A61F2/2433 ,  A61F2/2436 ,  A61F2220/0016 ,  A61F2230/005 ,  A61F2230/0054 ,  A61F2230/0067 ,  A61F2230/0078 ,  A61F2230/008 ,  A61F2250/0029 ,  A61F2250/0048

Abstract: A collapsible valve prosthesis includes an armature and a set of prosthetic valve leaflets supported by the armature. The armature is expandable from a contracted condition to an expanded condition for anchoring at an annulus of a natural valve site, and includes a tubular intra-annular portion defining a blood flow lumen having an inflow side and an outflow side. The tubular intra-annular portion supports the prosthetic valve leaflets in the blood flow lumen and is provided with outward formations for coupling with the natural valve site. The armature includes an over-annular portion linked to the intra-annular portion to extend collar-like over the annulus of the natural valve site at the inflow side of the blood flow lumen. The armature may also include an under-annular portion to extend collar-like at the outflow side of the blood flow lumen. The prosthesis may permit mitral valve replacement (MVR) without removing the native valve leaflets and the chordae tendineae.

Abstract translation: 可折叠瓣膜假体包括电枢和由电枢支撑的一组假体瓣膜小叶。 电枢从收缩状态膨胀到膨胀状态，用于锚定在自然阀位的环状部，并且包括限定具有流入侧和流出侧的血流腔的管状环状内部。 管状环形内部部分支撑血流腔中的假体瓣膜小叶，并且设置有用于与天然瓣膜部位联接的向外构造。 电枢包括连接到内环形部分的过环形部分，以在血流腔的流入侧处在自然瓣膜部位的环上延伸颈圈状。 电枢还可以包括在血流腔的流出侧处延伸环状的下环形部分。 假体可以允许二尖瓣置换（MVR），而不需要去除天然瓣叶和腱索。

公开(公告)号：US20130172991A1

公开(公告)日：2013-07-04

申请号：US13729636

申请日：2012-12-28

Applicant: Sorin Group Italia S.r.l.

Inventor： Giovanni Rolando ,  Paolo Gaschino ,  Monica Achiluzzi ,  Felice Giuseppe Carlino

IPC: A61F2/24

CPC classification number: A61F2/243 ,  A61F2/06 ,  A61F2/064 ,  A61F2/2409 ,  A61F2/2427 ,  A61F2/2436 ,  A61F2002/9522 ,  Y10T29/49412

Abstract: A kit for implanting a prosthetic vascular conduit includes a prosthetic vascular conduit for coupling to a prosthetic valve having an annular portion. The conduit includes a terminal collar member for receiving the valve. The kit further includes a holder including a shaft and a hub including a receiving portion configured for housing a prosthetic valve. The conduit is fitted on the holder so that at least a portion of the conduit wraps over the receiving portion of the hub. A sleeve member fitted onto the conduit in a position corresponding to the receiving portion of the hub, and a portion of the collar member is wrapped or folded over the sleeve member. The sleeve member is slidable away from the hub to unwrap the collar member such that it is disposed around the annular portion of a prosthetic valve.

Abstract translation: 用于植入假体血管导管的套件包括用于联接到具有环形部分的假体瓣膜的假体血管导管。 导管包括用于接收阀的端子套环构件。 套件还包括保持器，其包括轴和毂，包括构造成容纳人造瓣膜的接收部分。 导管安装在保持器上，使得至少一部分导管缠绕在毂的接收部分上。 套筒构件在对应于轮毂的接收部分的位置中安装到导管上，并且套环构件的一部分被卷绕或折叠在套筒构件上。 套筒构件可以从轮毂滑动以展开套环构件，使得其围绕假肢瓣膜的环形部分设置。