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公开(公告)号:US20180153170A1
公开(公告)日:2018-06-07
申请号:US15888289
申请日:2018-02-05
Applicant: Syngenta Participations AG
Inventor: Jerome Yves CASSAYRE , Peter RENOLD , Myriem EL QACEMI , Thomas PITTERNA , Julie Clementine TOUEG
IPC: A01N43/80 , C07D413/14 , C07D413/12 , C07D261/02 , C07D327/02 , C07D411/12
CPC classification number: A01N43/80 , C07D261/02 , C07D327/02 , C07D411/12 , C07D413/12 , C07D413/14
Abstract: The present invention provides compounds of formula (I): wherein A1, A2, A3 and A4 are independently of one another C—H, C—R5, or nitrogen; B1-B2-B3-B4 is —CH2—C═N—CH2—, —CH2—N—CH2—CH2—, —CH2—C═CH—O— or —CH═C—CH2—O—; G1 is oxygen or sulfur; L is a single bond or C1-C8alkylene; R1 is hydrogen, C1-C8alkyl, C1-C8alkylcarbonyl-, C1-C8alkoxy, C2-C8alkenyl, C2-C8alkynyl, C1-C8alkoxy-C1-C8alkyl, aryl or aryl substituted by one to three R6, or R1 is heterocyclyl or heterocyclyl substituted by one to three R6 or C1-C8alkoxycarbonyl-; R2 is hydrogen, C1-C8haloalkyl or C1-C8alkyl; R3 is C1-C8haloalkyl; R4 is aryl or aryl substituted by one to three R6, or R4 is heterocyclyl or heterocyclyl substituted by one to three R6; Y1 is CR7R8, C—O or C═S; Y2, Y3 and Y4 are independently CR7R8, C═O, C═S, N—R9, O, S, SO or SO2; wherein at least two adjacent ring atoms in the ring formed by Y1, Y2, Y3 and Y4 are heteroatoms; each R7 and R8 is independently hydrogen, halogen, C1-C8alkyl, or C1-C8haloalkyl; and R5, R6, R7, R8 and R9 are as defined in the claims. The invention also relates to processes and intermediates for preparing these compounds, to insecticidal, acaricidal, nematicidal and molluscicidal compositions comprising these compounds and to methods of using these compounds to control insect, acarine, nematode and mollusc pests.
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2.
公开(公告)号:US20180110226A1
公开(公告)日:2018-04-26
申请号:US15568829
申请日:2016-04-18
Applicant: Syngenta Participations AG
Inventor: Pierre Joseph Marcel JUNG , Andrew EDMUNDS , Michel MUEHLEBACH , Peter RENOLD , Roger Graham HALL , Jerome Yves CASSAYRE
IPC: A01N43/90 , C07D471/04 , C07D409/12 , A01N43/40
CPC classification number: A01N43/90 , A01N43/40 , C07D409/12 , C07D471/04
Abstract: Compounds of formula (I) wherein Q is (Q1) or (Q2); and wherein the other substituents are as defined in claim 1, and the agrochemically acceptable salts, stereoisomers, enantiomers, tautomers and N-oxides of those compounds, can be used as insecticides and can be prepared in a manner known per se.
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公开(公告)号:US20170000133A1
公开(公告)日:2017-01-05
申请号:US15107038
申请日:2014-12-23
Applicant: SYNGENTA PARTICIPATIONS AG
Inventor: Ramya RAJAN , Peter RENOLD , Atul MAHAJAN , Daniel STIERLI , Renaud BEAUDEGNIES
IPC: A01N55/08 , A23L3/3544 , A23B7/154 , C07F5/02
CPC classification number: A01N55/08 , A23B7/154 , A23L3/3544 , A23V2002/00 , C07F5/025
Abstract: Compounds of formula (I) are as defined in the claims, and their use in compositions and methods for the control and/or prevention of microbial infection, particularly fungal infection, in plants and to processes for the preparation of these compounds.
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公开(公告)号:US20190315728A1
公开(公告)日:2019-10-17
申请号:US16389116
申请日:2019-04-19
Applicant: Syngenta Participations AG
Inventor: Jerome Yves CASSAYRE , Peter RENOLD , Thomas PITTERNA , Myriem EL QACEMI
IPC: C07D413/12 , C07D409/12 , A01N43/36 , A01N43/80 , C07D331/04
Abstract: The present invention relates to processes for the preparation of thietane derivatives of the formula IA and thietane derivatives of the formula IB wherein R1, R2, A1, A2, A3, A4, B, and n are as defined in the claims. The invention also relates to intermediates useful in the processes, as well as the compounds of formula IA and IB and their use as pesticides.
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公开(公告)号:US20180000090A1
公开(公告)日:2018-01-04
申请号:US15542695
申请日:2016-01-13
Applicant: SYNGENTA PARTICIPATIONS AG
Inventor: Ramya RAJAN , Daniel STIERLI , Renaud BEAUDEGNIES , Peter RENOLD
Abstract: Compounds of formula (I) are as defined in the claims, and their use in compositions and methods for the control and/or prevention of microbial infection, particularly fungal infection, in plants and to processes for the preparation of these compounds.
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公开(公告)号:US20170071207A1
公开(公告)日:2017-03-16
申请号:US15361838
申请日:2016-11-28
Applicant: Syngenta Participations AG
Inventor: Jerome Yves CASSAYRE , Peter RENOLD , Myriem EL QACEMI , Thomas PITTERNA , Julie Clementine TOUEG
IPC: A01N43/80 , C07D413/14 , C07D413/12
CPC classification number: A01N43/80 , C07D261/02 , C07D327/02 , C07D411/12 , C07D413/12 , C07D413/14
Abstract: The present invention provides compounds of formula (I): wherein A1, A2, A3 and A4 are independently of one another C—H, C—R5, or nitrogen; B1—B2—B3—B4 is —CH2—C═N—CH2—, —CH2—N—CH2—CH2—, —CH2—C═CH—O— or —CH═C—CH2—O—; G1 is oxygen or sulfur; L is a single bond or C1-C8alkylene; R1 is hydrogen, C1-C8alkyl, C1-C8alkylcarbonyl-, C1-C8alkoxy, C2-C8alkenyl, C2-C8alkynyl, C1-C8alkoxy-C1-C8alkyl, aryl or aryl substituted by one to three R6, or R1 is heterocyclyl or heterocyclyl substituted by one to three R6 or C1-C8alkoxycarbonyl-; R2 is hydrogen, C1-C8haloalkyl or C1-C8alkyl; R3 is C1-C8haloalkyl; R4 is aryl or aryl substituted by one to three R6, or R4 is heterocyclyl or heterocyclyl substituted by one to three R6; Y1 is CR7R8, C═O or C═S; Y2, Y3 and Y4 are independently CR7R8, C═O, C═S, N—R9, O, S, SO or SO2; wherein at least two adjacent ring atoms in the ring formed by Y1, Y2, Y3 and Y4 are heteroatoms; each R7 and R8 is independently hydrogen, halogen, C1-C8alkyl, or C1-C8haloalkyl; and R5, R6, R7, R8 and R9 are as defined in the claims. The invention also relates to processes and intermediates for preparing these compounds, to insecticidal, acaricidal, nematicidal and molluscicidal compositions comprising these compounds and to methods of using these compounds to control insect, acarine, nematode and mollusc pests.
Abstract translation: 本发明还涉及制备这些化合物的方法和中间体,包含这些化合物的杀虫,杀螨,杀线虫和杀软体动物的组合物,以及使用这些化合物来控制昆虫,螨虫,线虫和软体动物害虫的方法。
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公开(公告)号:US20170000132A1
公开(公告)日:2017-01-05
申请号:US15107018
申请日:2014-12-23
Applicant: SYNGENTA PARTICIPATIONS AG
Inventor: Ramya RAJAN , Daniel STIERLI , Atul MAHAJAN , Renaud BEAUDEGNIES , Peter RENOLD
CPC classification number: A01N55/08 , A01N25/04 , A23L3/3544 , C07F5/025 , C07F5/027
Abstract: Compounds of formula (I) are as defined in the claims, and their use in compositions and methods for the control and/or prevention of microbial infection, particularly fungal infection, in plants and to processes for the preparation of these compounds.
Abstract translation: 式(I)化合物如权利要求中所定义,以及它们在用于控制和/或预防植物中微生物感染,特别是真菌感染的组合物和方法中的用途以及用于制备这些化合物的方法。
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8.
公开(公告)号:US20160073631A1
公开(公告)日:2016-03-17
申请号:US14945924
申请日:2015-11-19
Applicant: Syngenta Participations AG , Syngenta Limited
Inventor: Myriem EL QACEMI , Helmars SMITS , Jerome Yves CASSAYRE , Nicholas Phillip MULHOLLAND , Peter RENOLD , Edouard GODINEAU , Thomas PITTERNA
IPC: A01N43/36 , C07D207/20 , C07D207/46 , C07C255/41 , C07D207/22 , C07D209/48 , C07D331/04 , C07C255/44 , C07C251/24 , C07C205/54 , C07D249/08
CPC classification number: A01N43/36 , A01N33/20 , A01N37/34 , A01N37/44 , A01N37/46 , A01N43/20 , A01N43/40 , A01N43/653 , C07C205/54 , C07C251/24 , C07C255/41 , C07D207/20 , C07D207/22 , C07D207/46 , C07D209/48 , C07D249/08 , C07D331/04
Abstract: The present invention provides stereoselective processes for the preparation of compounds of formula (I) wherein P is phenyl, naphthyl, a 6-membered heteroaryl group containing one or two nitrogen atoms as ring members, or a 10-membered bicyclic heteroaryl group containing one or two nitrogen atoms as ring members, and wherein the phenyl, naphthyl and heteroaryl groups are optionally substituted; R1 is chlorodifluoromethyl or trifluoromethyl; R2 is optionally substituted aryl or optionally substituted heteroaryl; n is 0 or 1; including the process comprising (a-i) reacting a compound of formula II wherein P, R1 and R2 are as defined for the compound of formula I; with nitromethane in the presence a chiral catalyst to give a compound of formula III wherein P, R1 and R2 are as defined for the compound of formula I; and (a-ii) reductively cyclising the compound of formula III to give the compound of formula I. The invention also provides intermediates useful for processes for the synthesis of compounds of formula (I).
Abstract translation: 本发明提供了制备式(I)化合物的立体选择性方法,其中P是苯基,萘基,含有一个或两个氮原子作为环成员的6元杂芳基或含有一个或多个氮原子的10元双环杂芳基 两个氮原子作为环成员,并且其中苯基,萘基和杂芳基任选被取代; R1是氯二氟甲基或三氟甲基; R2是任选取代的芳基或任选取代的杂芳基; n为0或1; 包括(a-i)使式II化合物与式Ⅰ化合物反应的方法,其中P,R 1和R 2如对式I化合物所定义; 在硝基甲烷中存在手性催化剂,得到式III化合物,其中P,R 1和R 2如式I化合物所定义; 和(a-ii)还原性环化式III化合物以得到式I化合物。本发明还提供了可用于合成式(I)化合物的方法的中间体。
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公开(公告)号:US20200087292A1
公开(公告)日:2020-03-19
申请号:US16471501
申请日:2017-12-18
Applicant: SYNGENTA PARTICIPATIONS AG
Inventor: Myriem EL QACEMI , Jérôme Yves CASSAYRE , Thomas PITTERNA , André Stoller , Peter RENOLD
IPC: C07D413/12 , C07D205/04 , A01N43/80 , A01N43/44
Abstract: Compounds of formula (I) wherein the substituents are as defined in claim 1, and the agrochemically acceptable salts, stereoisomers, enantiomers, tautomers and N-oxides of those compounds, can be used as insecticides and can be prepared in a manner known per se.
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公开(公告)号:US20180244699A1
公开(公告)日:2018-08-30
申请号:US15753460
申请日:2016-08-16
Applicant: Syngenta Participations AG
Inventor: Ramya RAJAN , Peter RENOLD , Daniel STIERLI , Renaud BEAUDEGINES
Abstract: Compounds of formula (I) wherein R1 is fluorine, chlorine, bromine, cyano, nitro, hydroxy, C1-C4alkoxy, C1-C4haloalkoxy; G=OR2, NR3R4R2, R3 and R4 independently are selected H, alkyl, aryl, heteroaryl, cacloalkyl, heterocycloalkyl, wherein the alkyl, aryl, heteroaryl, cacloalkyl, heterocycloalkyl moieties may be further substituted; are useful as a pesticides especially fungicide.
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