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    Optically active thiazolidinone derivative
    5.
    发明授权
    Optically active thiazolidinone derivative 失效
    光学活性噻唑烷酮衍生物

    公开(公告)号：US5925658A

    公开(公告)日：1999-07-20

    申请号：US923745

    申请日：1997-09-02

    申请人： Sadao Ishihara ,  Fujio Saito ,  Yasuo Ohhata ,  Shigeki Miyake ,  Ryosuke Yorikane ,  Norio Fukuda

    发明人： Sadao Ishihara ,  Fujio Saito ,  Yasuo Ohhata ,  Shigeki Miyake ,  Ryosuke Yorikane ,  Norio Fukuda

    IPC分类号： C07D277/14 ,  A61K31/425

    CPC分类号： C07D277/14

    摘要： An optically active thiazolidinone derivative having the general formula: ##STR1## wherein: R.sup.1 represents a hydrogen atom, a C.sub.1 -C.sub.4 alkyl group, a phenyl group, a substituted phenyl group (said substituent represents C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy or halogen), a phenyl-C.sub.1 -C.sub.2 alkyl group or a substituted phenyl-C.sub.3 -C.sub.2 alkyl group (the substituent of said phenyl represents C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy or halogen); R.sup.2 represents a C.sub.1 -C.sub.6 alkyl group; and n represents 1 or 2!.EffectThe optically active thiazolidinone derivative of the present invention has excellent anti-angina pectoris action and is useful as a preventive agent or a therapeutic agent for angina pectoris.

    摘要翻译： 具有以下通式的光学活性噻唑烷酮衍生物：其中：R1表示氢原子，C1-C4烷基，苯基，取代苯基（所述取代基表示C1-C4烷基，C1-C4烷氧基或卤素）， 苯基-C 1 -C 2烷基或取代的苯基-C 3 -C 2烷基（所述苯基的取代基代表C1-C4烷基，C1-C4烷氧基或卤素）; R2表示C1-C6烷基; n表示1或2]。 效果本发明的光学活性噻唑烷酮衍生物具有优异的抗心绞痛作用，可用作心绞痛的预防剂或治疗剂。

    1,2,4-triazinone derivatives, their preparation and use
    9.
    发明授权
    1,2,4-triazinone derivatives, their preparation and use 失效
    1,2,4-三嗪酮衍生物，其制备和用途

    公开(公告)号：US4898862A

    公开(公告)日：1990-02-06

    申请号：US26290

    申请日：1987-03-16

    申请人： Yasuhiro Morisawa ,  Mitsuru Kataoka ,  Mitsuo Sugiyama ,  Fujio Saito ,  Hiroyuki Koike ,  Takeshi Oshima ,  Yasuo Simoji ,  Hitoshi Nagahori

    发明人： Yasuhiro Morisawa ,  Mitsuru Kataoka ,  Mitsuo Sugiyama ,  Fujio Saito ,  Hiroyuki Koike ,  Takeshi Oshima ,  Yasuo Simoji ,  Hitoshi Nagahori

    IPC分类号： C07D253/06 ,  C07D401/12 ,  C07D403/12

    CPC分类号： C07D253/06 ,  C07D401/12 ,  C07D403/12

    摘要： Compounds of formula (I): ##STR1## (in which: R.sup.1 is hydrogen or alkl; R.sup.2 is a variety of groups or atoms; R.sup.3 is optionally substituted hydroxy or --(NH).sub.n --NR.sup.5 R.sup.6, wherein R.sup.5 and R.sup.6 are a variety of groups or atoms, preferably alkyl substituted by heterocyclic, and n is 0 or 1; Q is oxygen or sulfur; and A is a C.sub.1 -C.sub.6 alkylene group) have valuable cardiotionic activity and may be used for the treatment of cardiac disorders. They may be prepared from corresponding compounds containing a benzene ring with a group --QH at the 1-position and a group --CO--CHR.sup.1 --NH--COOR.sup.7 at the 4-position by ring closure and introduction of the group of formula --A--CO--R.sup.3 in any order.

    摘要翻译： 式（I）化合物：其中：R 1是氢或烷基; R 2是各种基团或基团; R 3是任选取代的羟基或 - （NH）n -NR 5 R 6，其中R 5和R 6 是各种基团或原子，优选被杂环取代的烷基，n为0或1; Q为氧或硫; A为C1-C6亚烷基）具有有价值的心血管活性，可用于治疗心脏 疾病 它们可以由相应的化合物制备，所述化合物含有1-环基团-QH的苯环和通过闭环在4-位上的-CO-CHR1-NH-COOR7基团，并引入式-A- CO-R3以任何顺序。

    Client-server type network
    10.
    发明授权
    Client-server type network 失效
    客户端 - 服务器类型网络

    公开(公告)号：US5708834A

    公开(公告)日：1998-01-13

    申请号：US410710

    申请日：1995-03-27

    申请人： Kenichi Sasaki ,  Akibumi Mochizuki ,  Makoto Kawachi ,  Shigeyuki Hayashi ,  Yasuyoshi Katsuragawa ,  Fujio Saito ,  Mina Suzuki ,  Kazuhiko Ashizawa

    发明人： Kenichi Sasaki ,  Akibumi Mochizuki ,  Makoto Kawachi ,  Shigeyuki Hayashi ,  Yasuyoshi Katsuragawa ,  Fujio Saito ,  Mina Suzuki ,  Kazuhiko Ashizawa

    IPC分类号： G06F13/00 ,  H04L29/06 ,  G06F7/00

    CPC分类号： H04L29/06 ,  H04L67/42

    摘要： A client-server type network having at least two clients which execute the same kind of operation. The server and the clients are improved in order to realize addition or reduction in the number of clients. When the client is started, the fact that the client in under operation is recorded in the data base of the server. Since the addition of a client is automatically recorded in the server, the addition is easily facilitated. The server is provided with a client managing device for judging whether or not the client is under operation by polling. If the client is stopped due to a problem or the like, the fact is automatically recorded in the data base of the server. Therefore, it is also easy to eliminate the client from the data base of the server.

    摘要翻译： 具有至少两个执行相同操作类型的客户端的客户端 - 服务器类型网络。 改进了服务器和客户端，以实现客户数量的增加或减少。 当客户端启动时，正在运行的客户端被记录在服务器的数据库中。 由于客户端的添加被自动记录在服务器中，所以添加容易。 该服务器设置有用于通过轮询来判断客户端是否正在运行的客户端管理装置。 如果客户端由于问题等而被停止，则该事实被自动记录在服务器的数据库中。 因此，从服务器的数据库中消除客户端也很容易。