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1.发明申请PEPTIDE FOR INHIBITION OF BINDING BETWEEN ANGIOPOIETIN-2 AND INTEGRIN AND USE THEREOF 审中-公开用于抑制血管平滑肌蛋白-2与整合素之间的结合的肽及其用途公开(公告)号：US20160101154A1
公开(公告)日：2016-04-14
申请号：US14919386
申请日：2015-10-21
Applicant: Samsung Electronics Co., Ltd.
Inventor： Sang Yeul Han , Chung Ho Kim , Kyung Eun Kim , Hyung-Chan Kim , Kwang-Hoon Lee , Hyo Seon Lee
IPC: A61K38/18 , C07K14/515
CPC classification number: A61K38/1891 , A61K38/00 , C07K14/00 , C07K14/001 , C07K14/515 , C07K2319/30 , C07K2319/70
Abstract: Angiopoietin-2 (Ang2) derived peptides, polypeptides, and peptide complexes, and a method for inhibition of binding between Ang2 and integrin and prevention and/or treatment of a disease caused by the activation of Ang2 or the binding between Ang2 and integrin using the peptide, polypeptides, and peptide complexes.
Abstract translation: 促血管生成素-2（Ang2）来源的肽，多肽和肽复合物，以及用于抑制Ang2与整联蛋白之间的结合的方法，以及预防和/或治疗由Ang2的活化引起的疾病或Ang2和整联蛋白之间的结合 肽，多肽和肽复合物。
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Patent Agency Ranking
公开(公告)号：US09527910B2
公开(公告)日：2016-12-27
申请号：US14322343
申请日：2014-07-02
Applicant: Samsung Electronics Co., Ltd.
Inventor： Yoon Sook Lee , Chung Ho Kim , Kyung Eun Kim , Hyung-Chan Kim , Kwang Hoon Lee , Hyo Seon Lee , Sang Yeul Han
CPC classification number: C07K16/22 , C07K2317/34 , C07K2317/76 , C07K2317/92 , G01N33/74 , G01N2333/515 , G01N2800/7014
Abstract: Provided are an anti-Ang-2 antibody or antigen-binding fragment thereof that specifically binds to an angiogenesis-inducing factor Angiopoietin-2 (Ang-2), related compositions and pharmaceutical compositions, and methods for using such compositions and pharmaceutical compositions.
Abstract translation: 提供特异性结合血管发生诱导因子促血管生成素-2（Ang-2），相关组合物和药物组合物的抗Ang-2抗体或其抗原结合片段，以及使用这些组合物和药物组合物的方法。
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3.发明授权Peptide for inhibition of binding between angiopoietin-2 and integrin and use thereof 有权抑制血管生成素-2与整联蛋白结合的肽及其用途公开(公告)号：US09193768B2
公开(公告)日：2015-11-24
申请号：US14058069
申请日：2013-10-18
Applicant: Samsung Electronics Co., Ltd.
Inventor： Sang Yeul Han , Chung Ho Kim , Kyung Eun Kim , Hyung-Chan Kim , Kwang-Hoon Lee , Hyo Seon Lee
IPC: C07K14/00 , C07K14/515 , A61K38/00
CPC classification number: A61K38/1891 , A61K38/00 , C07K14/00 , C07K14/001 , C07K14/515 , C07K2319/30 , C07K2319/70
Abstract: There are provided an angiopoietin-2 (Ang2) derived peptides, polypeptides, and peptide complexes, and a method for inhibition of binding between Ang2 and integrin and prevention and/or treatment of a disease caused by the activation of Ang2 or the binding between Ang2 and integrin using the peptide, polypeptides, and peptide complexes.
Abstract translation: 提供了血管生成素-2（Ang2）衍生的肽，多肽和肽复合物，以及抑制Ang2和整联蛋白之间结合的方法，以及预防和/或治疗Ang2的激活或Ang2的结合引起的疾病 和使用肽，多肽和肽复合物的整联蛋白。
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公开(公告)号：US20150037343A1
公开(公告)日：2015-02-05
申请号：US14447242
申请日：2014-07-30
Applicant: Samsung Electronics Co., Ltd.
Inventor： Seok Kyun KIM , Sang Yeul Han , Kwang Hoon Lee , Kyung Eun Kim , Chung Ho Kim , Yong In Kim , Hyung-Chan Kim , Yoon Sook Lee , Hyo Seon Lee
CPC classification number: C07K16/22 , A61K2039/505 , C07K2317/21 , C07K2317/34 , C07K2317/622 , C07K2317/76 , C07K2317/92 , G01N2500/04 , Y02A50/412
Abstract: An Ang2 specific antibody, a method of inhibiting angiogenesis or a method of treating a disease related to the activation and/or overproduction of Ang2 using the antibody, and a composition for diagnosing a disease related to the activation and/or overproduction of Ang2 including the antibody.
Abstract translation: Ang2特异性抗体，抑制血管生成的方法或使用该抗体治疗与Ang2的活化和/或过量产生有关的疾病的方法，以及用于诊断与Ang2的活化和/或过量产生有关的疾病的组合物，包括 抗体。
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公开(公告)号：US10047154B2
公开(公告)日：2018-08-14
申请号：US14447242
申请日：2014-07-30
Applicant: Samsung Electronics Co., Ltd.
Inventor： Seok Kyun Kim , Sang Yeul Han , Kwang Hoon Lee , Kyung Eun Kim , Chung Ho Kim , Yong In Kim , Hyung-Chan Kim , Yoon Sook Lee , Hyo Seon Lee
IPC: A61K39/395 , A61K39/00 , C07K16/00 , C07K16/22
Abstract: An Ang2 specific antibody, a method of inhibiting angiogenesis or a method of treating a disease related to the activation and/or overproduction of Ang2 using the antibody, and a composition for diagnosing a disease related to the activation and/or overproduction of Ang2 including the antibody.
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公开(公告)号：US20150010572A1
公开(公告)日：2015-01-08
申请号：US14322343
申请日：2014-07-02
Applicant: Samsung Electronics Co., Ltd.
Inventor： Yoon Sook LEE , Chung Ho Kim , Kyung Eun Kim , Hyung-Chan Kim , Kwang Hoon Lee , Hyo Seon Lee , Sang Yeul Han
CPC classification number: C07K16/22 , C07K2317/34 , C07K2317/76 , C07K2317/92 , G01N33/74 , G01N2333/515 , G01N2800/7014
Abstract: Provided are an anti-Ang-2 antibody or antigen-binding fragment thereof that specifically binds to an angiogenesis-inducing factor Angiopoietin-2 (Ang-2), related compositions and pharmaceutical compositions, and methods for using such compositions and pharmaceutical compositions.
Abstract translation: 提供特异性结合血管发生诱导因子促血管生成素-2（Ang-2），相关组合物和药物组合物的抗Ang-2抗体或其抗原结合片段，以及使用这些组合物和药物组合物的方法。
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