摘要:
The present invention is an immortalized B-cell line which produces a human monoclonal antibody IgG-Kk which specifically binds to the envelope antigen of human T-cell leukemia virus Type 1 (HTLV-I). This monoclonal antibody is useful as a diagnostic reagent by binding to the antigen specifically expressed on the surface of HTLV producing cells. Furthermore, this monoclonal antibody is useful as a therapeutic reagent, in combination with complement, for the lysis of HTLV-1 producing cells.
摘要:
An auto-focusing system includes a focus condition detector which detects focus condition based on the infrared light. A data producer is provided for producing a deflection signal indicating a difference between an image forming distance for the infrared light and that for the visible light, due to aberration. In accordance with the detected focus condition and deflection signal, an objective lens is shifted to a position for properly focusing an image of visible light on an image forming plane.
摘要:
An active focus detecting device for use in a camera is provided and includes emitting light that is polarized, and collimated so that the light forms a light bundle which will pass near the optical axis of the objective lens, and then will be projected in a diverging light path after having been focused by the objective lens towards the object. A polarization component is provided for receiving the returning light and directing a component of that light towards a detector for determining a focusing condition.
摘要:
In an interchangeable lens including an optical system adjustable for focusing and adapted to be detachably mounted on a camera body which is provided with focus detection means for detecting an amount of defocus of an object image formed by the optical system, and drive means for driving the optical system for the focus adjustment thereof in accordance with the detected amount of defocus. The interchangeable lens comprises, inter alia, a code plate for producing a plurality of digital photographic distance signals representing given discrete photographic distances of the optical system in accordance with the adjustment of the optical system for focusing. Circuit means output a predetermined one of a plurality of inputs, the plurality of outputs including a plurality of conversion coefficients needed for converting the detected amount of defocus into the amount of drive to be effected by the driving means, the conversion coefficients being intrinsic to the interchangeable lens and having values depending upon the discrete photographic distances of the optical system represented by the digital photographic distance signals, respectively.The digital photographic distance signals are applied to the circuit means as the predetermined input to cause the circuit means to output one of the conversion coefficients as the predetermined output, the value of which depends upon the photographic distance of the optical system represented by the one digital photographic distance signal being produced. The output conversion coefficient are transmitted to the camera body.
摘要:
A camera in which a plurality of photographic data are input by manual key operations is made easily operable with less possibility of erroneous data input by inadvertent key operations. The data to be input are classified into first and second groups in accordance with the relevancy of the respective data or the frequency of changing of the respective data during photographing operations. In one embodiment, first and second photographic data setting sections are separately provided at different positions and input keys included in the first data setting section are used for the input of the first group data whereas input keys included in the second data setting section are used for the input of the second group data. In another embodiment, input keys common to the first and second group data setting are included in a single photographic data setting section. The data input by the input keys are those of the first group with a setting data-indicating plate being at a closed position but changed-over to those of the second group with the setting data-indicating plate being moved to an opened position. A flat-type indication device for indication of the input data is provided on a flat oblique surface of the camera descending from the front to the rear of the camera to facilitate its observation.
摘要:
The present invention provides a monoclonal antibody that recognizes the V3 loop of the envelope glycoprotein gp120 of AIDS virus, which is any one selected from the following antibodies: (a) an antibody having the amino acid sequence shown in SEQ ID NO: 1 as the amino acid sequence of a H chain variable region (VH), and having the amino acid sequence shown in SEQ ID NO: 2 as the amino acid sequence of a L chain variable region (VL); and (b) an antibody having the amino acid sequence shown in SEQ ID NO: 3 as the amino acid sequence of a H chain variable region (VH), and having the amino acid sequence shown in SEQ ID NO: 4 as the amino acid sequence of a L chain variable region (VL).
摘要翻译:本发明提供识别AIDS病毒的包膜糖蛋白gp120的V3环的单克隆抗体,其是选自以下抗体中的任一种:(a)具有SEQ ID NO:1所示的氨基酸序列的抗体作为 具有H链可变区(VH)的氨基酸序列,并且具有SEQ ID NO:2所示的氨基酸序列作为L链可变区(VL)的氨基酸序列; 和(b)具有SEQ ID NO:3所示的氨基酸序列的抗体作为H链可变区(VH)的氨基酸序列,并且具有SEQ ID NO:4所示的氨基酸序列作为氨基酸 L链可变区(VL)的序列。
摘要:
The present invention is directed to an antibody or fragment thereof, modified with a toxic substance capable of substantially inhibiting the growth of human cells infected with viruses, which is prepared by conjugating a substance capable of chemically and/or physically inducing cytotoxicity against human cells infected with HIV with an antibody or fragment thereof capable of specifically reacting with at least one antigen of said viruses, by using a pharmacologically inert substance as a carrier. The antibodies according to the present invention may be used, for example, in the diagnosis, prevention and curing of chronic disorders induced by viral infections, e.g. AIDS and leukemia, since they are not only capable of inhibiting the growth of the virus-producing cells and capable of killing such cells but also are capable of neutralizing the viruses without inhibiting the growth of uninfected cells.
摘要:
An auto-focusing system includes a focus condition detector which detects the focus condition based on infrared light. A data producer is provided for producing a deflection signal indicating the difference between an image forming distance for infrared light and that for visible light, due to aberration. In accordance with the detected focus condition and deflection signal, an objective lens is shifted to a position for properly focusing an image of visible light on an image forming plane.
摘要:
Disclosed are exchangeable lenses for use in single lens reflex cameras which include a diaphragm setting ring having an indicia for automatic aperture control and an aperture scale for manual aperture setting thereon, the scale extending from a mininum f-number to a maximum f-number of the respective lenses. The diaphragm setting ring is able to set to a desired f-number position within the scale or set to the indicia. The diaphragm setting ring is provided with a single information transmitting member whose position relative to the aperture scale is such that the member may transmit information as to the step-difference between a desired set f-number and the minimum f-number, by coupling with an information receiving member on a camera body, to an exposure indicating and/or control mechanisms in the camera body when the ring is set to any one of the manual aperture setting positions, and in such a position relative to the indicia that the member may also transmit information as to the minimum f-number of the lens through the same coupling to the camera body mechanism when the ring is set to an automatic aperture control position. Without any other information transmitting and receiving members, the cameras utilizing these lenses are capable of receiving information as to the minimum f-number of the lens mounted on their body upon automatic diaphragm control and thus the cameras may indicate an f-number corresponding to aperture to be automatically controlled before commencement of a stopping-down operation.
摘要:
The present invention relates to monoclonal antibody 0.5.beta. which binds to an epitope located within the region of amino acids 308-331 of HTLVIIIB gp120 and is capable of substantially neutralising the activity of human immunodeficiency viruses, to a hybridoma which produces the 0.5.beta. antibody, to processes for preparing them and to compositions containing an effective amount of the antibody.