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公开(公告)号：US5989818A
公开(公告)日：1999-11-23
申请号：US941262
申请日：1997-09-30
CPC分类号： C07K14/47
摘要： The invention provides a human rSec6 related vesicle transport protein (HSEC6) and polynucleotides which identify and encode HSEC6. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of HSEC6.
摘要翻译： 本发明提供了一种人类rSec6相关囊泡转运蛋白（HSEC6）和识别和编码HSEC6的多核苷酸。 本发明还提供表达载体，宿主细胞，激动剂，抗体和拮抗剂。 本发明还提供了治疗与HSEC6表达相关的疾病的方法。
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公开(公告)号：US20140147863A1
公开(公告)日：2014-05-29
申请号：US13697978
申请日：2011-05-13
申请人： Sidney E O'Bryant , Robert Clinton Barber , Ramon Diaz-Arrastia , Guanghua Xiao , Peirrie Milton Adams , Joan Snavely Reisch , Rachelle Smith Doody , Thomas John Fairchild , Ralph L. McDade , Samuel T. Labrie
发明人： Sidney E O'Bryant , Robert Clinton Barber , Ramon Diaz-Arrastia , Guanghua Xiao , Peirrie Milton Adams , Joan Snavely Reisch , Rachelle Smith Doody , Thomas John Fairchild , Ralph L. McDade , Samuel T. Labrie
IPC分类号： G01N33/543
CPC分类号： G01N33/54306 , C12Q1/6883 , C12Q2600/156 , G01N33/6896
摘要： Methods and devices for predicting, diagnosing, monitoring, or determining Alzheimer's disease in a human are described. In particular, methods and devices for predicting diagnosing, monitoring, or determining AD using measured concentrations of a combination of three or more analytes in a test sample taken from the human are described.
摘要翻译： 描述了用于人类中预测，诊断，监测或测定阿尔茨海默病的方法和装置。 具体地，描述了使用来自人的测试样品中三种或更多种分析物的组合的测量浓度来预测诊断，监测或确定AD的方法和装置。
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公开(公告)号：US20110177959A1
公开(公告)日：2011-07-21
申请号：US12852322
申请日：2010-08-06
申请人： Michael D. Spain , James P. Mapes , Samuel T. Labrie , Ralph L. McDade , Dominic P. Eisinger , Karri L. Ballard , Daniel R. Salomon , Michael Abecassis
发明人： Michael D. Spain , James P. Mapes , Samuel T. Labrie , Ralph L. McDade , Dominic P. Eisinger , Karri L. Ballard , Daniel R. Salomon , Michael Abecassis
IPC分类号： C40B30/02
CPC分类号： G01N33/6893 , G01N33/5302 , G01N33/566 , G01N2333/47 , G01N2333/4703 , G01N2333/4706 , G01N2333/4725 , G01N2333/4727 , G01N2333/475 , G01N2333/52 , G01N2333/70503 , G01N2333/70539 , G01N2333/765 , G01N2333/775 , G01N2333/8139 , G01N2333/8146 , G01N2333/82 , G01N2333/91177 , G01N2800/34 , G01N2800/347 , G01N2800/52 , G01N2800/56 , G01N2800/60 , Y10T436/147777
摘要： Methods and devices for diagnosing, monitoring, or determining kidney transplant rejection or an associated disorder in a mammal are described. In particular, methods and devices for diagnosing, monitoring, or determining kidney transplant rejection or an associated disorder using measured concentrations of a combination of three or more analytes in a test sample taken from the mammal are described.
摘要翻译： 描述了用于诊断，监测或确定哺乳动物的肾移植排斥或相关病症的方法和装置。 具体地，描述了使用从哺乳动物获取的测试样品中测量浓度的三种或更多种分析物的组合来诊断，监测或确定肾移植排斥或相关疾病的方法和装置。
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4.发明申请Methods and Devices for Detecting Diabetic Nephropathy and Associated Disorders 审中-公开检测糖尿病肾病和相关疾病的方法和装置公开(公告)号：US20110065598A1
公开(公告)日：2011-03-17
申请号：US12852282
申请日：2010-08-06
IPC分类号： C40B30/04
CPC分类号： G01N33/6893 , G01N33/5302 , G01N33/566 , G01N2333/47 , G01N2333/4703 , G01N2333/4706 , G01N2333/4725 , G01N2333/4727 , G01N2333/475 , G01N2333/52 , G01N2333/70503 , G01N2333/70539 , G01N2333/765 , G01N2333/775 , G01N2333/8139 , G01N2333/8146 , G01N2333/82 , G01N2333/91177 , G01N2800/34 , G01N2800/347 , G01N2800/52 , G01N2800/56 , G01N2800/60 , Y10T436/147777
摘要： Methods and devices for diagnosing, monitoring, or determining diabetic nephropathy or an associated disorder in a mammal are described. In particular, methods and devices for diagnosing, monitoring, or determining diabetic nephropathy or an associated disorder using measured concentrations of a combination of three or more analytes in a test sample taken from the mammal are described.
摘要翻译： 描述了用于诊断，监测或确定哺乳动物中的糖尿病性肾病或相关疾病的方法和装置。 具体地，描述了使用从哺乳动物获取的测试样品中测量的三种或更多种分析物的组合的测量浓度来诊断，监测或确定糖尿病性肾病或相关疾病的方法和装置。
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公开(公告)号：US06204372B1
公开(公告)日：2001-03-20
申请号：US08812824
申请日：1997-03-06
申请人： Samuel T. Labrie , Preeti Lal , Lynn E. Murry
发明人： Samuel T. Labrie , Preeti Lal , Lynn E. Murry
IPC分类号： C12N1500
CPC分类号： C07K14/5759 , A61K38/00
摘要： The present invention provides a novel human tubby homolog (NHT) and polynucleotides which identify and encode NHT. The invention also provides expression vectors, host cells, agonists, antibodies, or antagonists. The invention also provides methods for treating disorders associated with appetite and eating.
摘要翻译： 本发明提供了一种新型人类卵母细胞同源物（NHT）和识别和编码NHT的多核苷酸。 本发明还提供表达载体，宿主细胞，激动剂，抗体或拮抗剂。 本发明还提供了治疗与食欲和饮食相关的疾病的方法。
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6.发明授权Methods and devices for detecting obstructive uropathy and associated disorders 有权用于检测阻塞性病变和相关疾病的方法和装置公开(公告)号：US08735080B2
公开(公告)日：2014-05-27
申请号：US12852236
申请日：2010-08-06
申请人： Samuel T. Labrie , James P. Mapes , Ralph L. McDade , Dominic Eisinger , Karri L. Ballard , Michael D. Spain
发明人： Samuel T. Labrie , James P. Mapes , Ralph L. McDade , Dominic Eisinger , Karri L. Ballard , Michael D. Spain
IPC分类号： G01N33/53
CPC分类号： G01N33/6893 , G01N33/5302 , G01N33/566 , G01N2333/47 , G01N2333/4703 , G01N2333/4706 , G01N2333/4725 , G01N2333/4727 , G01N2333/475 , G01N2333/52 , G01N2333/70503 , G01N2333/70539 , G01N2333/765 , G01N2333/775 , G01N2333/8139 , G01N2333/8146 , G01N2333/82 , G01N2333/91177 , G01N2800/34 , G01N2800/347 , G01N2800/52 , G01N2800/56 , G01N2800/60 , Y10T436/147777
摘要： Methods and devices for diagnosing, monitoring, or determining obstructive uropathy or an associated disorder in a mammal are described. In particular, methods and devices for diagnosing, monitoring, or determining obstructive uropathy or an associated disorder using measured concentrations of a combination of three or more analytes in a test sample taken from the mammal are described.
摘要翻译： 描述了用于诊断，监测或确定哺乳动物中的阻塞性尿病或相关疾病的方法和装置。 具体地，描述了使用从哺乳动物取得的测试样品中测量浓度的三种或更多种分析物的组合来诊断，监测或确定阻塞性尿病或相关疾病的方法和装置。
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公开(公告)号：US20110065593A1
公开(公告)日：2011-03-17
申请号：US12852202
申请日：2010-08-06
申请人： Samuel T. Labrie , James P. Mapes , Ralph L. McDade , Dominic Eisinger , Karri L. Ballard , Michael D. Spain
发明人： Samuel T. Labrie , James P. Mapes , Ralph L. McDade , Dominic Eisinger , Karri L. Ballard , Michael D. Spain
CPC分类号： G01N33/6893 , G01N33/5302 , G01N33/566 , G01N2333/47 , G01N2333/4703 , G01N2333/4706 , G01N2333/4725 , G01N2333/4727 , G01N2333/475 , G01N2333/52 , G01N2333/70503 , G01N2333/70539 , G01N2333/765 , G01N2333/775 , G01N2333/8139 , G01N2333/8146 , G01N2333/82 , G01N2333/91177 , G01N2800/34 , G01N2800/347 , G01N2800/52 , G01N2800/56 , G01N2800/60 , Y10T436/147777
摘要： Methods and devices for diagnosing, monitoring, or determining a renal disorder in a mammal are described. In particular, methods and devices for diagnosing, monitoring, or determining a renal disorder using measured concentrations of a combination of three or more analytes in a test sample taken from the mammal are described.
摘要翻译： 描述了用于诊断，监测或确定哺乳动物肾脏疾病的方法和装置。 具体地，描述了使用从哺乳动物取得的测试样品中使用测量浓度的三种或更多种分析物的组合来诊断，监测或确定肾脏疾病的方法和装置。
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8.发明申请Methods and Devices for Detecting Glomerulonephritis and Associated Disorders 审中-公开检测肾小球肾炎和相关疾病的方法和装置公开(公告)号：US20110065136A1
公开(公告)日：2011-03-17
申请号：US12852152
申请日：2010-08-06
申请人： Samuel T. Labrie , James P. Mapes , Ralph L. McDade , Dominic P. Eisinger , Karri L. Ballard , Michael D. Spain
发明人： Samuel T. Labrie , James P. Mapes , Ralph L. McDade , Dominic P. Eisinger , Karri L. Ballard , Michael D. Spain
CPC分类号： G01N33/6893 , G01N33/5302 , G01N33/566 , G01N2333/47 , G01N2333/4703 , G01N2333/4706 , G01N2333/4725 , G01N2333/4727 , G01N2333/475 , G01N2333/52 , G01N2333/70503 , G01N2333/70539 , G01N2333/765 , G01N2333/775 , G01N2333/8139 , G01N2333/8146 , G01N2333/82 , G01N2333/91177 , G01N2800/34 , G01N2800/347 , G01N2800/52 , G01N2800/56 , G01N2800/60 , Y10T436/147777
摘要： Methods and devices for diagnosing, monitoring, or determining glomerulonephritis or an associated disorder in a mammal are described. In particular, methods and devices for diagnosing, monitoring, or determining glomerulonephritis or an associated disorder using measured concentrations of a combination of three or more analytes in a test sample taken from the mammal are described.
摘要翻译： 描述了用于诊断，监测或测定哺乳动物中的肾小球性肾炎或相关病症的方法和装置。 具体地说，描述了从哺乳动物取得的测试样品中使用测量浓度的三种或更多种分析物的组合来诊断，监测或测定肾小球肾炎或相关疾病的方法和装置。
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