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公开(公告)号：US6110685A
公开(公告)日：2000-08-29
申请号：US283763
申请日：1999-04-01
申请人： Sanjoy Biswas , James Raymond Brown , Martin Karl Russel Burnham , Alison Francis Chalker , Richard Lloyd Warren , Magdalena Zalacain , Chi Young So , Christopher M Traini , David John Holmes , Karen Anne Ingraham , Thomas B Mathie
发明人： Sanjoy Biswas , James Raymond Brown , Martin Karl Russel Burnham , Alison Francis Chalker , Richard Lloyd Warren , Magdalena Zalacain , Chi Young So , Christopher M Traini , David John Holmes , Karen Anne Ingraham , Thomas B Mathie
CPC分类号： C07K14/3156 , A61K38/00 , A61K39/00 , A61K48/00 , Y10S435/885
摘要： The invention provides infB polypeptides and polynucleotides encoding in polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing infB polypeptides to screen for antibacterial compounds.
摘要翻译： 本发明提供了在多肽中编码的infB多肽和多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用infB多肽筛选抗菌化合物的方法。
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2.发明授权Polynucleotides encoding tRNA methyl transferases from Streptococcus pneumoniae 有权编码来自肺炎链球菌的tRNA甲基转移酶的多核苷酸
公开(公告)号：US6165764A
公开(公告)日：2000-12-26
申请号：US274825
申请日：1999-03-23
申请人： David John Holmes , Karen Anne Ingraham , Thomas B Mathie , Richard Lloyd Warren , Magdalena Zalacain , Sanjoy Biswas , James Raymond Brown , Chi Young So , Alison Francis Chalker
发明人： David John Holmes , Karen Anne Ingraham , Thomas B Mathie , Richard Lloyd Warren , Magdalena Zalacain , Sanjoy Biswas , James Raymond Brown , Chi Young So , Alison Francis Chalker
CPC分类号： C12N9/1007 , A61K38/00 , A61K39/00 , A61K48/00
摘要： The invention provides tRNA methyl transferase (trmD) polypeptides and polynucleotides encoding trmD polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing trmD polypeptides to screen for antibacterial compounds.
摘要翻译： 本发明提供tRNA甲基转移酶（trmD）多肽和编码trmD多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用trmD多肽筛选抗菌化合物的方法。
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公开(公告)号：US06399343B1
公开(公告)日：2002-06-04
申请号：US09574912
申请日：2000-05-19
申请人： Sanjoy Biswas , James Raymond Brown , Martin Karl Russel Burnham , Alison Francis Chalker , Richard Lloyd Warren , Magdalena Zalacain , Chi Young So , Christopher M Traini , David John Holmes , Karen Anne Ingraham , Thomas B Mathie
发明人： Sanjoy Biswas , James Raymond Brown , Martin Karl Russel Burnham , Alison Francis Chalker , Richard Lloyd Warren , Magdalena Zalacain , Chi Young So , Christopher M Traini , David John Holmes , Karen Anne Ingraham , Thomas B Mathie
IPC分类号： C12N900
CPC分类号： C07K14/3156 , A61K38/00 , A61K39/00 , A61K48/00 , Y10S435/885
摘要： The invention provides infB polypeptides and polynucleotides encoding infB polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing in polypeptides to screen for antibacterial compounds.
摘要翻译： 本发明提供编码infB多肽的infB多肽和多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了在多肽中利用筛选抗菌化合物的方法。
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公开(公告)号：US06350600B1
公开(公告)日：2002-02-26
申请号：US09627769
申请日：2000-07-28
申请人： Sanjoy Biswas , James Raymond Brown , Chi Young So , Alison Francis Chalker , David John Holmes , Karen Anne Ingraham , Thomas B Mathie , Richard Lloyd Warren , Magdalena Zalacain
发明人： Sanjoy Biswas , James Raymond Brown , Chi Young So , Alison Francis Chalker , David John Holmes , Karen Anne Ingraham , Thomas B Mathie , Richard Lloyd Warren , Magdalena Zalacain
IPC分类号： C12N900
CPC分类号： C12N9/1007 , A61K38/00 , A61K39/00 , A61K48/00
摘要： The invention provides trmA methyl transferase (trmD) polypeptides and polynucleotides encoding trmD polypeptides and methods for producing such polypeptides by recominant techniques from strepococcus pneumoniae. Also provided are methods for utilizing polypepides to screen for antibacterial compounds.
摘要翻译： 本发明提供trmA甲基转移酶（trmD）多肽和编码trmD多肽的多核苷酸以及通过来自肺炎链球菌的重组技术产生此类多肽的方法。 还提供了利用多肽来筛选抗菌化合物的方法。
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公开(公告)号：US06225457B1
公开(公告)日：2001-05-01
申请号：US09305001
申请日：1999-05-04
申请人： Sanjoy Biswas , James Raymond Brown , Martin K R Burnham , Alison Francis Chalker , David John Holmes , Karen Anne Ingraham , Thomas B Mathie , Richard Lloyd Warren , Magdalena Zalacain
发明人： Sanjoy Biswas , James Raymond Brown , Martin K R Burnham , Alison Francis Chalker , David John Holmes , Karen Anne Ingraham , Thomas B Mathie , Richard Lloyd Warren , Magdalena Zalacain
IPC分类号： C07H2104
CPC分类号： C07K14/3156 , A61K38/00 , A61K48/00 , C07K2319/00
摘要： The invention provides murF2 polypeptides and polynucleotides encoding murF2 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing murF2 polypeptides to screen for antibacterial compounds.
摘要翻译： 本发明提供了编码murF2多肽的murF2多肽和多核苷酸以及通过重组技术产生这种多肽的方法。 还提供了利用murF2多肽筛选抗菌化合物的方法。
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公开(公告)号：US06268177B1
公开(公告)日：2001-07-31
申请号：US09285576
申请日：1999-04-02
申请人： Sanjoy Biswas , James Raymond Brown , Martin Karl Russel Burnham , Alison Francis Chalker , David John Holmes , Karen Anne Ingraham , Thomas B Mathie , Richard Lloyd Warren , Magdalena Zalacain
发明人： Sanjoy Biswas , James Raymond Brown , Martin Karl Russel Burnham , Alison Francis Chalker , David John Holmes , Karen Anne Ingraham , Thomas B Mathie , Richard Lloyd Warren , Magdalena Zalacain
IPC分类号： C12N1500
CPC分类号： C12N9/1077
摘要： The invention provides ndp polypeptides and polynucleotides encoding ndp polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ndp polypeptides to screen for antibacterial compounds.
摘要翻译： 本发明提供了ndp多肽和编码ndp多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用ndp多肽筛选抗菌化合物的方法。
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公开(公告)号：US6117662A
公开(公告)日：2000-09-12
申请号：US310293
申请日：1999-05-12
IPC分类号： C12N15/09 , A61K38/00 , A61K39/08 , A61K39/395 , A61K45/00 , A61P31/04 , C07K14/31 , C07K16/14 , C12N9/06 , C12N15/53 , C12P21/00 , C12Q1/68 , C12N9/02 , C12N15/03 , C12N15/62
CPC分类号： C12N9/0044
摘要： The invention provides respiratory nitrate reductase alpha subunit polypeptides and polynucleotides encoding respiratory nitrate reductase alpha subunit polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing respiratory nitrate reductase alpha subunit polypeptides to screen for antibacterial compounds.
摘要翻译： 本发明提供了呼吸性硝酸还原酶α亚基多肽和编码呼吸性硝酸还原酶α亚单位多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用呼吸性硝酸还原酶α亚基多肽筛选抗菌化合物的方法。
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公开(公告)号：US06316237B1
公开(公告)日：2001-11-13
申请号：US09579376
申请日：2000-05-26
IPC分类号： C12N900
CPC分类号： C12N9/0044
摘要： The invention provides respiratory nitrate reductase alpha subunit polypeptides and polynucleotides encoding respiratory nitrate reductase alpha subunit polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing respiratory nitrate reductase alpha subunit polypeptides to screen for antibacterial compounds.
摘要翻译： 本发明提供了呼吸性硝酸还原酶α亚基多肽和编码呼吸性硝酸还原酶α亚单位多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用呼吸性硝酸还原酶α亚基多肽筛选抗菌化合物的方法。
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