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1.发明授权Method for predicting response to epidermal growth factor receptor-directed therapy 有权预测表皮生长因子受体导向治疗反应的方法公开(公告)号：US07771958B2
公开(公告)日：2010-08-10
申请号：US11548386
申请日：2006-10-11
IPC分类号： G01N33/574 , G01N33/567 , G01N33/577
CPC分类号： A61K38/1808 , A61K2039/505 , C07K16/2863
摘要： This invention provides methods for determining or predicting response to cancer therapy in an individual.
摘要翻译： 本发明提供了确定或预测个体对癌症治疗反应的方法。
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2.发明申请Method for Predicting Response to Epidermal Growth Factor Receptor-Directed Therapy 有权预测表皮生长因子受体定向治疗反应的方法公开(公告)号：US20070134252A1
公开(公告)日：2007-06-14
申请号：US11548386
申请日：2006-10-11
申请人： Sarah Bacus , David Lynch , Pamela Lockbaum , Gisela Schwab , Xiao-dong Yang
发明人： Sarah Bacus , David Lynch , Pamela Lockbaum , Gisela Schwab , Xiao-dong Yang
IPC分类号： A61K39/395 , G01N33/574
CPC分类号： A61K38/1808 , A61K2039/505 , C07K16/2863
摘要： This invention provides methods for determining or predicting response to cancer therapy in an individual.
摘要翻译： 本发明提供了确定或预测个体对癌症治疗反应的方法。
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公开(公告)号：US20060293506A1
公开(公告)日：2006-12-28
申请号：US11109181
申请日：2005-04-18
申请人： Jose Corvalan , Xiao-Chi Jia , Xiao Feng , Xiao-dong Yang , Francine Chen , Gadi Gazit , Richard Weber , Binyam Bezabeh
发明人： Jose Corvalan , Xiao-Chi Jia , Xiao Feng , Xiao-dong Yang , Francine Chen , Gadi Gazit , Richard Weber , Binyam Bezabeh
IPC分类号： C07K16/22
CPC分类号： C07K16/22 , C07K2317/21 , C07K2317/56
摘要： The present invention is related to antibodies directed to the antigen PDGFD and uses of such antibodies. In particular, in accordance with the present invention, there are provided fully human monoclonal antibodies directed to the antigen PDGFD. Nucelotide sequences encoding, and amino acid sequences comprising, heavy and light chain immunoglobulin molecules, particularly sequences corresponding to contiguous heavy and light chain sequences spanning the framework regions and/or complementarity determining regions (CDR's), specifically from FR1 through FR4 or CDR1 through CDR3, are provided. Hybridomas or other cell lines expressing such immunoglobulin molecules and monoclonal antibodies are also provided.
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公开(公告)号：US07135174B2
公开(公告)日：2006-11-14
申请号：US10041860
申请日：2002-01-07
申请人： Jose R. F. Corvalan , Xiao-Chi Jia , Xiao Feng , Xiao-dong Yang , Francine Chen , Gadi Gazit , Richard Weber , Binyam Bezabeh
发明人： Jose R. F. Corvalan , Xiao-Chi Jia , Xiao Feng , Xiao-dong Yang , Francine Chen , Gadi Gazit , Richard Weber , Binyam Bezabeh
IPC分类号： A61K39/395 , C07K16/22
CPC分类号： C07K16/22 , C07K2317/21 , C07K2317/56
摘要： The present invention is related to antibodies directed to the antigen PDGFD and uses of such antibodies. In particular, in accordance with the present invention, there are provided fully human monoclonal antibodies directed to the antigen PDGFD. Nucelotide sequences encoding, and amino acid sequences comprising, heavy and light chain immunoglobulin molecules, particularly sequences corresponding to contiguous heavy and light chain sequences spanning the framework regions and/or complementarity determining regions (CDR's), specifically from FR1 through FR4 or CDR1 through CDR3, are provided. Hybridomas or other cell lines expressing such immunoglobulin molecules and monoclonal antibodies are also provided.
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