公开(公告)号：US07099513B2

公开(公告)日：2006-08-29

申请号：US10175510

申请日：2002-06-18

申请人： Schuyler Cullen ,  Edward R. Ratner ,  Rasmus Larsen ,  David B. Kita

发明人： Schuyler Cullen ,  Edward R. Ratner ,  Rasmus Larsen ,  David B. Kita

IPC分类号： G06K9/36

CPC分类号： G06T9/005 ,  H04N19/147 ,  H04N19/61 ,  H04N19/63

摘要： A process and apparatus for allocating bits between the stages of a multi-stage digital image compression scheme with quantizer feedback is disclosed. The process selects a quantization schedule (from a finite number of possibilities) for all stages that minimizes an estimate of total distortion while keeping total bit demand below a constraint; uses said schedule to actually quantize one stage of the compression scheme; selects a new quantization schedule for the remaining stages using estimates for distortion and bit demand that are updated to reflect the quantization of the previous stage; actually quantizes the next stage according to the new quantization schedule; and continues recursively until it has chosen an actual quantization scale for every stage of the compression scheme.

公开(公告)号：US07358083B1

公开(公告)日：2008-04-15

申请号：US09673617

申请日：1999-04-14

申请人： Kim Sorensen ,  Rasmus Larsen ,  Eric Johansen

发明人： Kim Sorensen ,  Rasmus Larsen ,  Eric Johansen

IPC分类号： C12N15/74 ,  C12N1/21 ,  C12N15/68 ,  A23C9/123

CPC分类号： C12N15/746 ,  A23C9/123 ,  A23C2220/202

摘要： Novel food-grade cloning vectors comprising a nonsense mutation suppressor-encoding gene, which vector, when it is present in a lactic acid bacterial strain, permits such a strain to have an industrially appropriate growth rate and metabolic activity. The cloning vectors are useful when present in lactic acid bacteria used as starter cultures in the preparation of food or feed products, or a dairy flavor.

摘要翻译： 包含无义突变抑制子编码基因的新型食品级克隆载体，当该载体存在于乳酸菌株中时，该载体允许这种菌株具有工业上合适的生长速率和代谢活性。 当存在于用作食品或饲料产品或乳制品风味剂的起始培养物的乳酸菌中时，克隆载体是有用的。

公开(公告)号：US20060063146A1

公开(公告)日：2006-03-23

申请号：US10533324

申请日：2003-10-31

申请人： Rasmus Larsen ,  Frans Ejner Hansen

发明人： Rasmus Larsen ,  Frans Ejner Hansen

IPC分类号： C12Q1/70 ,  C12Q1/68 ,  G01N33/53 ,  G01N33/567

CPC分类号： G01N33/54313

摘要： The invention relates to imaging methods for assessing quality or quantity parameters of particles in a sample, wherein the particles contain less than 106 analyte detectable positions. The method comprises 1) mixing the sample with a targeting species capable of binding an analyte position and a labelling agent, 2) arranging the sample in an exposing domain, allowing electromagnetic signals from the sample to pass to the exterior, 3) exposing a representation of said signals onto an array of detection elements, wherein the representation is subject to a linear enlargement, so that the ratio of the image of a linear dimension on the array of detection elements to the original linear dimension in the exposing domain is smaller than 20:1, 4) detecting the representation as intensities by said detection elements, 5) processing the intensities to identify the particles, and 6) obtaining the quality or quantity parameter.

摘要翻译： 本发明涉及用于评估样品中颗粒的质量或数量参数的成像方法，其中所述颗粒含有小于10 6个分析物的可检测位置。 该方法包括：1）将样品与能够结合分析物位置的靶向物质和标记试剂混合，2）将样品置于曝光区域，允许来自样品的电磁信号传递到外部，3） 的所述信号传送到检测元件的阵列上，其中所述表示经历线性放大，使得检测元件阵列上的线性尺寸的图像与曝光区域中的原始线性尺寸的比率小于20 ：1,4）通过所述检测元件检测所述表示为强度，5）处理所述强度以识别所述粒子，以及6）获得所述质量或数量参数。

公开(公告)号：US20050148085A1

公开(公告)日：2005-07-07

申请号：US10489930

申请日：2002-09-16

申请人： Rasmus Larsen

发明人： Rasmus Larsen

IPC分类号： G01N15/02 ,  G01N15/14 ,  G01N33/52 ,  G01N33/569 ,  G01N33/48

CPC分类号： G01N15/02 ,  G01N15/14 ,  G01N33/52 ,  G01N33/56911 ,  G01N33/56966 ,  G01N33/56972

摘要： The invention relates to the field of detecting and optionally collecting and isolating rare event particles. The method according to the invention is based on relatively simple optical equipment, which requires a few and uncomplicated decisions for the user of the system. The method is based on the acquisition of an image of relatively low resolution and magnification of a large volume of sample and detecting the presence or absence of the rare event particle. The method is then repeated with at least one further volume of sample. The method is particularly adapted for detection of white blood cells in leuko-depleted blood.

摘要翻译： 本发明涉及检测和任选地收集和分离稀有事件颗粒的领域。 根据本发明的方法是基于相对简单的光学设备，其需要对系统的用户的几个且不复杂的决定。 该方法基于获取大体积样本的相对低分辨率和放大倍率的图像，并且检测稀有事件粒子的存在或不存在。 然后用至少一个另外的体积的样品重复该方法。 该方法特别适用于白细胞贫血血液中白细胞的检测。