公开(公告)号：US20080019914A1

公开(公告)日：2008-01-24

申请号：US11775663

申请日：2007-07-10

申请人： Scott Bintrim ,  Scott Bevan ,  Baolong Zhu ,  Donald Merlo

发明人： Scott Bintrim ,  Scott Bevan ,  Baolong Zhu ,  Donald Merlo

IPC分类号： A01N63/00 ,  A01P7/04 ,  C07H21/04 ,  C07K14/00 ,  C07K14/32 ,  C12N1/20 ,  C12N1/21 ,  C12N5/04

CPC分类号： C12P19/34 ,  C07K14/195 ,  C12P21/02 ,  C12Q1/689 ,  C12Q2600/142

摘要： The subject invention provides unique biological alternatives for pest control. More specifically, the present invention relates to novel pesticidal proteins, novel sources of pesticidal proteins, polynucleotides that encode such toxins, and to methods of using these toxins to control insects and other plant pests. The subject invention relates to the surprising discovery that Paenibacillus species, and proteins therefrom, have toxicity to lepidopterans. There have been no known reports of a Paenibacillus species, strain, or protein having toxicity to lepidopterans. This is also the first known example of a Paenibacillus Cry protein that is toxic to lepidopterans. Furthermore, this is the first known report of a Paenibacillus having toxin complex (TC)-like proteins. The DAS1529 isolate disclosed here is also the first known example of a natural bacterium that produces both a Cry toxin and TC proteins. The subject invention also relates to new classes of Cry and TC proteins that are pesticidally active.

摘要翻译： 本发明提供了用于病虫害防治的独特的生物学替代物。 更具体地，本发明涉及新型杀虫蛋白，杀虫蛋白的新来源，编码这种毒素的多核苷酸，以及使用这些毒素来控制昆虫和其它植物害虫的方法。 本发明涉及令​​人惊奇的发现：Paenibacillus物种及其蛋白质对鳞翅目病毒具有毒性。 没有已知的具有对鳞翅目昆虫具有毒性的Paenibacillus物种，菌株或蛋白质的报道。 这也是对鳞翅目昆虫具有毒性的第一个已知的Paenibacillus Cry蛋白的例子。 此外，这是具有毒素复合物（TC）样蛋白质的Paenibacillus的第一个已知报告。 此处公开的DAS1529分离物也是产生Cry毒素和TC蛋白质的天然细菌的第一已知实例。 本发明还涉及具有杀虫活性的新类型的Cry和TC蛋白。

公开(公告)号：US20060156434A1

公开(公告)日：2006-07-13

申请号：US11375551

申请日：2006-03-14

申请人： Scott Bintrim ,  Jon Mitchell ,  Ignacio Larrinua ,  Patricia Apel-Birkhold ,  Susan Green ,  Barry Schafer ,  Scott Bevan ,  Scott Young ,  Lining Guo

发明人： Scott Bintrim ,  Jon Mitchell ,  Ignacio Larrinua ,  Patricia Apel-Birkhold ,  Susan Green ,  Barry Schafer ,  Scott Bevan ,  Scott Young ,  Lining Guo

IPC分类号： A01H1/00 ,  C07H21/04 ,  C12N15/82 ,  C12N5/04 ,  C07K14/195 ,  C07K14/415

CPC分类号： C12N15/8286 ,  Y02A40/162

摘要： The subject invention relates to novel Xenorhabdus toxin complex (TC) proteins and genes that encode these proteins. More specifically, the subject invention relates to TC genes and proteins obtainable from Xenorhabdus strain Xwi. The subject invention also provides an exochitinase obtainable from the Xwi strain. This exochitinase can be used to control insects using methods known in the art.