公开(公告)号：US20240156878A1

公开(公告)日：2024-05-16

申请号：US18535722

申请日：2023-12-11

Applicant: Seed Health, Inc.

Inventor： Tye Jensen ,  Joseph E. Kovarik ,  Raja Dhir

IPC: A61K35/74 ,  A61K31/58 ,  A61K31/715 ,  A61K38/17

CPC classification number: A61K35/74 ,  A61K31/58 ,  A61K31/715 ,  A61K38/1709 ,  A61K38/1758 ,  A61K2035/11

Abstract: Compositions, systems and methods of improving the health of the microbiome of an individual's skin relate to the provision of skin contacting formulations containing beneficial bacteria and other microbe components to foster the growth and maintenance of a healthy skin microbiome. Embodiments include methods for treating an individual suffering from acne valgaris by topically administering a composition that includes live bacteria selected from the group consisting of L reuteri, L johnsonii, L crispatus, C. acnes, and Nitrosomonas eutropha, that have been modified by using a using a clustered regularly interspaced short palindromic repeats (CRISPR) CRISPR associated protein (Cas) system or a CRISPR from Prevotella and Francisella 1 (Cpf1) system to reduce the production of a virulence factor of the bacteria.

公开(公告)号：US12150967B2

公开(公告)日：2024-11-26

申请号：US17269135

申请日：2019-08-19

Applicant: SEED HEALTH, INC.

Inventor： Gregor Reid ,  Brendan Daisley ,  Raja Dhir

IPC: A61K35/747 ,  A23K10/18 ,  A23K10/38 ,  A23K20/163 ,  A23K50/90 ,  A61K9/00 ,  A61K35/00 ,  A61P31/00

Abstract: The present disclosure relates to compositions, methods and systems for the prophylaxis and treatment of honey bees (e.g. Apis mellifera) to protect and/or treat certain diseases, disorders and conditions, e.g., Colony Collapse Disorder and American foulbrood. The present disclosure comprises probiotic compositions, and methods of use thereof, for administration to honey bees for the purposes of treating or preventing disease.

公开(公告)号：US12246043B2

公开(公告)日：2025-03-11

申请号：US18535722

申请日：2023-12-11

Applicant: Seed Health, Inc.

Inventor： Tye Jensen ,  Joseph E. Kovarik ,  Raja Dhir

IPC: A61K35/74 ,  A61K31/58 ,  A61K31/715 ,  A61K35/00 ,  A61K35/741 ,  A61K35/745 ,  A61K35/747 ,  A61K38/17 ,  C12N1/20

Abstract: Compositions, systems and methods of improving the health of the microbiome of an individual's skin relate to the provision of skin contacting formulations containing beneficial bacteria and other microbe components to foster the growth and maintenance of a healthy skin microbiome. Embodiments include methods for treating an individual suffering from acne valgaris by topically administering a composition that includes live bacteria selected from the group consisting of L. reuteri, L. johnsonii, L. crispatus, C. acnes, and Nitrosomonas eutropha, that have been modified by using a using a clustered regularly interspaced short palindromic repeats (CRISPR) CRISPR associated protein (Cas) system or a CRISPR from Prevotella and Francisella 1 (Cpf1) system to reduce the production of a virulence factor of the bacteria.

公开(公告)号：US11998574B2

公开(公告)日：2024-06-04

申请号：US18235686

申请日：2023-08-18

Applicant: Seed Health, Inc.

Inventor： Sheri Simmons ,  Tye Jensen ,  Raja Dhir ,  Joseph E. Kovarik

IPC: A61K35/74 ,  A61K31/58 ,  A61K31/715 ,  A61K35/00 ,  A61K38/17

CPC classification number: A61K35/74 ,  A61K31/58 ,  A61K31/715 ,  A61K38/1709 ,  A61K38/1758 ,  A61K2035/11

Abstract: Compositions, systems and methods of improving the health of the microbiome of an individual's skin relate to the provision of skin contacting formulations containing beneficial bacteria, postbiotics, metabolites and other microbe components to foster the growth and maintenance of a healthy skin microbiome. One embodiment includes a topical application of Lactobacillus crispatus to ameliorate skin barrier damage and inflammation using unique combinations of probiotics, prebiotics, postbiotics, and other skin-beneficial ingredients, effectively treating inflammatory skin diseases, such as atopic dermatitis, psoriasis and acne, through the production of tryptophan metabolites that act as AHR agonists.

公开(公告)号：USD1023764S1

公开(公告)日：2024-04-23

申请号：US29831918

申请日：2022-03-23

Applicant: Seed Health Inc.

Designer： Ara Katz ,  Raja Dhir ,  Yuji Sakuma ,  Chelsea Beloff

Abstract: FIG. 1 is a front perspective view of embodiment one, of a container, showing our new design;
FIG. 2 is a front elevation view thereof;
FIG. 3 is a rear elevation thereof;
FIG. 4 is a right side elevation view thereof;
FIG. 5 is a left side elevation view thereof;
FIG. 6 is a top plan view thereof;
FIG. 7 is a bottom plan view thereof;
FIG. 8 is a cross-sectional side view thereof taken along line 8-8 shown in FIG. 6;
FIG. 9 is an exploded side view thereof;
FIG. 10 is an exploded and cross-sectional side view thereof taken along line 10-10 shown in FIG. 6;
FIG. 11 is an exploded perspective view thereof;
FIG. 12 is a front perspective view of embodiment two, of a container, showing our new design;
FIG. 13 is a front elevation view of the container of FIG. 12;
FIG. 14 is a rear elevation view of the container of FIG. 12;
FIG. 15 is a right side elevation view of the container of FIG. 12;
FIG. 16 is a left side elevation view of the container of FIG. 12;
FIG. 17 is a top plan view of the container of FIG. 12;
FIG. 18 is a bottom plan view of the container of FIG. 12;
FIG. 19 is a cross-sectional side view of the container of FIG. 12 taken along line 19-19 shown in FIG. 17;
FIG. 20 is an exploded side view of the container of FIG. 12;
FIG. 21 is an exploded and cross-sectional side view of the container of FIG. 12 taken along line 21-21 shown in FIG. 17;
FIG. 22 is an exploded perspective view of the container of FIG. 12;
FIG. 23 is a front perspective view of embodiment three, of a container, showing our new design;
FIG. 24 is a front elevation view of the container of FIG. 23;
FIG. 25 is a rear elevation view of the container of FIG. 23;
FIG. 26 is a right side elevation view of the container of FIG. 23;
FIG. 27 is a left side elevation view of the container of FIG. 23;
FIG. 28 is a top plan view of the container of FIG. 23;
FIG. 29 is a bottom plan view of the container of FIG. 23;
FIG. 30 is a cross-sectional side view of the container of FIG. 23 taken along line 30-30 shown in FIG. 28;
FIG. 31 is an exploded side view of the container of FIG. 23;
FIG. 32 is an exploded and cross-sectional side view of the container of FIG. 23 taken along line 32-32 shown in FIG. 28; and,
FIG. 33 is an exploded perspective view of the container of FIG. 23.
The broken lines show portions of the container which form no part of the claimed design.