利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

5 条记录 (耗时 0.017 秒)

    Processes for the recovery of optically active diacyltartaric acids
    1.
    发明授权
    Processes for the recovery of optically active diacyltartaric acids 有权
    回收光学活性二酰基酒石酸的方法

    公开(公告)号：US07358384B2

    公开(公告)日：2008-04-15

    申请号：US10542498

    申请日：2003-12-22

    申请人： Seiji Morii ,  Toshihiro Fujino ,  Haruyo Sato

    发明人： Seiji Morii ,  Toshihiro Fujino ,  Haruyo Sato

    IPC分类号： C07C69/76 ,  C07C69/66 ,  C07C51/42 ,  C07C59/255

    CPC分类号： C07C67/52 ,  C07B2200/07 ,  Y02P20/582 ,  C07C69/76

    摘要： When a salt of an amine and an optically active diacyltartaric acid, or a diastereomer salt of an optically active amine and an optically active diacyltartaric acid, obtained by optically resolving a racemic amine using the optically active diacyltartaric acid, is salt-exchanged with an acid aqueous solution, the optically active diacyltartaric acid is added in the acid aqueous solution beforehand.Furthermore, a raw material containing a racemic amine and an optically active diacyltartaric acid is optically resolved, and the diastereomer salt of the optically active amine and the optically active diacyltartaric acid respectively of one isomer type, is separated. The obtained diastereomer salt is dissociated using an acid aqueous solution containing the optically active diacyltartaric acid, for recovering the optically active diacyltartaric acid, and the obtained optically active diacyltartaric acid is recycled into an optical resolution step as a raw material of the optical resolution step.

    摘要翻译： 当通过光学拆分外消旋胺使用光学活性的二酰基酒石酸获得的胺和光学活性二酰基酒石酸盐或光学活性胺和光学活性二酰基酒石酸的非对映体盐与酸盐交换时， 水溶液中，将光学活性的二酰基酒石酸预先加入到酸性水溶液中。 此外，含有外消旋胺和光学活性二酰基酒石酸的原料被光学拆分，分离出一种异构体类型的光学活性胺和光学活性二酰基酒石的非对映异构体盐。 使用含有光学活性二酰基酒石酸的酸性水溶液使得到的非对映异构体盐解离，回收光学活性的二酰基酒石酸，将得到的光学活性二酰基酒石再循环至作为光学拆分工序的原料的光学拆分工序。

    Processes for the recovery of optically active diacyltartatic acids
    2.
    发明申请
    Processes for the recovery of optically active diacyltartatic acids 有权
    回收光学活性二酰基鞣酸的方法

    公开(公告)号：US20060058546A1

    公开(公告)日：2006-03-16

    申请号：US10542498

    申请日：2003-12-22

    申请人： Seiji Morii ,  Toshihiro Fujino ,  Haruyo Sato

    发明人： Seiji Morii ,  Toshihiro Fujino ,  Haruyo Sato

    IPC分类号： C07C69/86 ,  C07C69/66

    CPC分类号： C07C67/52 ,  C07B2200/07 ,  Y02P20/582 ,  C07C69/76

    摘要： When a salt of an amine and an optically active diacyltartaric acid, or a diastereomer salt of an optically active amine and an optically active diacyltartaric acid, obtained by optically resolving a racemic amine using the optically active diacyltartaric acid, is salt-exchanged with an acid aqueous solution, the optically active diacyltartaric acid is added in the acid aqueous solution beforehand. Furthermore, a raw material containing a racemic amine and an optically active diacyltartaric acid is optically resolved, and the diastereomer salt of the optically active amine and the optically active diacyltartaric acid respectively of one isomer type, is separated. The obtained diastereomer salt is dissociated using an acid aqueous solution containing the optically active diacyltartaric acid, for recovering the optically active diacyltartaric acid, and the obtained optically active diacyltartaric acid is recycled into an optical resolution step as a raw material of the optical resolution step.

    摘要翻译： 当通过光学拆分外消旋胺使用光学活性的二酰基酒石酸获得的胺和光学活性二酰基酒石酸盐或光学活性胺和光学活性二酰基酒石酸的非对映体盐与酸盐交换时， 水溶液中，将光学活性的二酰基酒石酸预先加入到酸性水溶液中。 此外，含有外消旋胺和光学活性二酰基酒石酸的原料被光学拆分，分离出一种异构体类型的光学活性胺和光学活性二酰基酒石的非对映异构体盐。 使用含有光学活性二酰基酒石酸的酸性水溶液使得到的非对映异构体盐解离，回收光学活性的二酰基酒石酸，将得到的光学活性二酰基酒石再循环至作为光学拆分工序的原料的光学拆分工序。

    Process for producing nitrogenous heterocyclic compound
    3.
    发明申请
    Process for producing nitrogenous heterocyclic compound 审中-公开
    含氮杂环化合物的制备方法

    公开(公告)号：US20060270847A1

    公开(公告)日：2006-11-30

    申请号：US10562405

    申请日：2004-06-22

    申请人： Seiji Morii ,  Takae Ono ,  Haruyo Sato

    发明人： Seiji Morii ,  Takae Ono ,  Haruyo Sato

    IPC分类号： C07D223/12 ,  C07D211/26

    CPC分类号： C07D207/12 ,  B01J23/44

    摘要： A nitrogenous heterocyclic compound such as 3-aminopyrrolidine derivative is produced by hydrogenolysis of an N-substituted nitrogenous heterocyclic compound with normal pressure hydrogen in a water-based solvent in presence of a catalyst. In the case an optically active 1-substituted-3-aminopyrrrolidine derivative is used as a raw material, an optically active 3-aminopyrrolidine derivative can be obtained as a product practically without racemination.

    摘要翻译： 通过在催化剂存在下，在水系溶剂中，用常压氢氢解N-取代的含氮杂环化合物，制得3-氨基吡咯烷衍生物等含氮杂环化合物。 在使用旋光性1-取代-3-氨基吡咯烷衍生物作为原料的情况下，可以获得光学活性的3-氨基吡咯烷衍生物作为产物，实际上没有外消旋化。