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公开(公告)号：US11701038B2
公开(公告)日：2023-07-18
申请号：US16709225
申请日：2019-12-10
发明人： Ravi Rastogi , James Masciotti , Xiaoxiao Chen
IPC分类号： A61B5/145 , A61B5/1495 , A61B5/07
CPC分类号： A61B5/1495 , A61B5/076 , A61B5/14503 , A61B5/14532 , A61B2560/0271 , A61B2560/0276
摘要： An analyte monitoring system and method. The analyte monitoring system may include an analyte sensor and a transceiver. The analyte sensor may include an analyte indicator that exhibits one or more detectable properties based on an amount or concentration of an analyte in proximity to the indicator. The transceiver may be configured to receive one or more measurements from the sensor. The transceiver may be configured to assess in real time a performance of the sensor based on at least the one or more measurements. The transceiver may be configured to determine whether the performance of the sensor is deficient based at least on the assessed performance of the sensor. The transceiver may be configured to calculate an analyte level based on at least the one or more sensor measurements. The transceiver may be configured to determine whether the calculated analyte level is a spike.
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公开(公告)号：US11185264B2
公开(公告)日：2021-11-30
申请号：US16142744
申请日：2018-09-26
发明人： Xiaoxiao Chen , Ravi Rastogi , Andrew DeHennis , Patricia Sanchez
IPC分类号： A61B5/1495 , A61B5/145 , A61B5/1459 , A61B5/00 , G01N33/66
摘要： Disclosed are analyte monitoring systems and methods for calibrating an analyte sensor using one or more reference measurements. These systems and methods may include using a conversion function and first sensor data to calculate a first sensor analyte level, weighting a first reference analyte measurement (RM1) and one or more previous reference analyte measurements according to a weighted average cost function, updating the conversion function using the weighted RM1 and the one or more weighted previous reference analyte measurements as calibration points, and using the updated conversion function and second sensor data to calculate a second sensor analyte level. In some aspects, the systems and methods may include updating one or more of lag parameters used to calculate the sensor analyte levels.
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公开(公告)号：US10772503B2
公开(公告)日：2020-09-15
申请号：US15167559
申请日：2016-05-27
发明人： Barkha Raisoni , David Lerner , Christina Long , Xiaoxiao Chen , Todd Whitehurst , Ravi Rastogi , Andrew Dehennis
IPC分类号： A61B5/00 , G16H40/67 , A61B5/145 , A61B5/1455 , A61B5/1495 , A61M5/172 , A61M5/142
摘要： A computing device receives analyte data produced by an analyte monitoring sensor over a communications link from at least one first device. Health data, comprising at least part of the analyte data, may be communicated over a communications link to at least one second device in response to a request. The first device may be positioned over the analyte monitoring sensor using signal strength and location information. External analyte data may be employed to calibrate the analyte monitoring sensor.
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公开(公告)号：US20200178855A1
公开(公告)日：2020-06-11
申请号：US16704275
申请日：2019-12-05
发明人： Xiaoxiao Chen , Ravi Rastogi
IPC分类号： A61B5/1473 , A61B5/00 , A61B5/145
摘要： Analyte monitoring systems and methods may include calculating an analyte level and an analyte level rate of change using at least measurement information conveyed by an analyte sensor, displaying the analyte level, determining whether the analyte level is lower than a first lower analyte level threshold, determining whether the analyte level is lower than a second lower analyte level threshold, comparing the analyte level rate of change to an analyte level rate of change threshold, and displaying one or more of a low analyte level alert and a rate of change alert. The low analyte level alert may be displayed if the analyte level is lower than the first lower analyte threshold, and the rate of change alert may be displayed if the analyte level is lower than the second lower analyte level threshold and the analyte level is changing faster than the analyte level rate of change threshold.
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公开(公告)号：US10674945B2
公开(公告)日：2020-06-09
申请号：US15715535
申请日：2017-09-26
发明人： Xiaoxiao Chen , Andrew Dehennis
摘要： An analyte monitoring system and method. The analyte monitoring system may include an analyte sensor and a transceiver. The analyte sensor may include an indicator element that exhibits one or more detectable properties based on a concentration of an analyte in proximity to the indicator element. The transceiver may be configured to (i) receive measurement information from the analyte sensor, (ii) calculate the concentration of the analyte in proximity to the indicator element based on at least the received measurement information, and (iii) calculate a blood analyte concentration based on the calculated concentration of the analyte in proximity to the indicator element by (1) incorporating the calculated concentration of the analyte in proximity to the indicator element into a governing equation that models analyte transport over an interval, and (2) solving the governing equation. In some embodiments, the governing equation includes no more than two discrete boundary conditions.
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公开(公告)号：US20190094231A1
公开(公告)日：2019-03-28
申请号：US16142664
申请日：2018-09-26
发明人： Xiaoxiao Chen , Ravi Rastogi , Andrew DeHennis , Patty Sanchez
IPC分类号： G01N33/66
摘要： Disclosed are analyte monitoring systems and methods for calibrating an analyte sensor using one or more reference measurements. These systems and methods may include using a conversion function and first sensor data to calculate a first sensor analyte level, weighting a first reference analyte measurement (RM1) and one or more previous reference analyte measurements according to a weighted average cost function, updating the conversion function using the weighted RM1 and the one or more weighted previous reference analyte measurements as calibration points, and using the updated conversion function and second sensor data to calculate a second sensor analyte level. In some aspects, the systems and methods may include updating one or more of lag parameters used to calculate the sensor analyte levels.
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7.发明公开公开(公告)号：US20240041368A1
公开(公告)日：2024-02-08
申请号：US18449623
申请日：2023-08-14
IPC分类号： A61B5/1495 , A61B5/00 , A61B5/145 , G01N33/66 , G01N33/96 , A61B5/15 , A61B5/1459
CPC分类号： A61B5/1495 , A61B5/0031 , A61B5/14532 , A61B5/742 , A61B5/14503 , G01N33/66 , G01N33/96 , A61B5/150022 , A61B5/1459 , A61B5/686 , A61B2560/0223 , A61B5/0004 , A61B5/15142
摘要： A method and transceiver for calibrating an analyte sensor using one or more reference measurements. In some embodiments, the method may include receiving a first reference analyte measurement (RM1) and determining whether the RM1 is unexpected. In some embodiments, the method may include, if the RM1 was determined to be unexpected, receiving a second reference analyte measurement (RM2). In some embodiments, the method may include determining whether one or more of the RM1 and the RM2 are acceptable as calibration points. In some embodiments, the method may include, if one or more of the RM1 and the RM2 are determined to be acceptable as calibration points, accepting one or more of the RM1 and the RM2 as calibration points. In some embodiments, the method may include calibrating the analyte sensor using at least one or more of the RM1 and the RM2 as calibration points.
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公开(公告)号：US20200178856A1
公开(公告)日：2020-06-11
申请号：US16709225
申请日：2019-12-10
发明人： Ravi Rastogi , James Masciotti , Xiaoxiao Chen
IPC分类号： A61B5/1495 , A61B5/07 , A61B5/145
摘要： An analyte monitoring system and method. The analyte monitoring system may include an analyte sensor and a transceiver. The analyte sensor may include an analyte indicator that exhibits one or more detectable properties based on an amount or concentration of an analyte in proximity to the indicator. The transceiver may be configured to receive one or more measurements from the sensor. The transceiver may be configured to assess in real time a performance of the sensor based on at least the one or more measurements. The transceiver may be configured to determine whether the performance of the sensor is deficient based at least on the assessed performance of the sensor. The transceiver may be configured to calculate an analyte level based on at least the one or more sensor measurements. The transceiver may be configured to determine whether the calculated analyte level is a spike.
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公开(公告)号：US20180279923A1
公开(公告)日：2018-10-04
申请号：US15939683
申请日：2018-03-29
发明人： Xiaoxiao Chen , Andrew Dehennis
IPC分类号： A61B5/145 , A61B5/1459 , A61B5/00
摘要： A system, transceiver, and method for calculating and correcting levels (e.g., analyte levels) in a first medium (e.g., blood) using measurements from a second medium (e.g., interstitial fluid). In some embodiments, a transceiver may calculate an initial second medium level. The transceiver may calculate an initial second medium level rate of change (“ROC”) using at least the initial second medium level and past second medium level(s). The transceiver may calculate a first medium level using at least the initial second medium level and the initial second medium level ROC. The transceiver may calculate a subsequent second medium level. The transceiver may calculate an updated second medium level ROC using at least the initial second medium level, the subsequent second medium level, and past second medium level(s). The transceiver may calculate a corrected first medium level using at least the initial second medium level and the updated second medium level ROC.
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10.发明申请公开(公告)号：US20180103879A1
公开(公告)日：2018-04-19
申请号：US15786954
申请日：2017-10-18
IPC分类号： A61B5/1495 , A61B5/00 , A61M5/172
CPC分类号： A61B5/1495 , A61B5/0024 , A61B5/0031 , A61B5/0062 , A61B5/0075 , A61B5/14532 , A61B2560/0223 , A61B2560/0247 , A61B2560/0271 , A61B2560/0276 , A61B2560/028 , A61M5/14244 , A61M5/1723 , A61M2205/3576 , A61M2205/50
摘要： An analyte monitoring system and method. The analyte monitoring system may include an analyte sensor and a transmitter. The analyte sensor may include an indicator element that exhibits one or more detectable properties based on an amount or concentration of an analyte in proximity to the indicator element. The transmitter may be configured to receive measurement information from the analyte sensor. The transmitter may be configured to assess in real time a performance of the analyte sensor based on at least the measurement information. The transmitter may be configured to determine whether the performance of the analyte sensor is deficient based at least on the assessed performance of the analyte sensor. The transmitter may be configured to predict an amount of time remaining before the performance of the analyte sensor becomes deficient based on at least the assessed performance of the analyte sensor.
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