公开(公告)号：US5203329A

公开(公告)日：1993-04-20

申请号：US805003

申请日：1991-12-11

申请人： Setsuo Takatani ,  Jonathan P. Jaeb ,  Ronald L. Branstetter ,  Hiroshi Sakai

发明人： Setsuo Takatani ,  Jonathan P. Jaeb ,  Ronald L. Branstetter ,  Hiroshi Sakai

IPC分类号： A61B5/00

CPC分类号： A61B5/14552

摘要： A noninvasive oximeter sensor for controlling and optimizing the minimum detection depth in the tissue of a patient is disclosed. In general, a minimum detection depth of 0.35 mm in the skin is considered optimum. The reflectance oximeter sensor component configuration of the present invention achieves the minimum detection depth. The present invention offers a more accurate indication of blood oxygen saturation in a patient's arterial blood than was available from previous reflectance oximeter sensors.

摘要翻译： 公开了一种用于控制和优化患者组织中的最小检测深度的无创血氧计传感器。 通常，皮肤中最小检测深度为0.35mm被认为是最佳的。 本发明的反射式血氧计传感器部件结构达到最小检测深度。 本发明提供了比先前的反射式血氧计传感器可获得的患者动脉血中血氧饱和度更准确的指示。

公开(公告)号：US5094239A

公开(公告)日：1992-03-10

申请号：US417320

申请日：1989-10-05

申请人： Jonathan P. Jaeb ,  Ronald L. Branstetter

发明人： Jonathan P. Jaeb ,  Ronald L. Branstetter

IPC分类号： A61B5/00

CPC分类号： A61B5/14551

摘要： An oximeter system for measuring blood oxygen saturation using a noninvasive optical technique is disclosed. A patient's arterial blood is illuminated with light at two different wavelengths and the intensity of the light which is transmitted through or reflected by said arterial blood is correlated with the blood oxygen saturation of the tissue. The system provides a manner in which filtering artifacts are avoided in the oximeter signal using a high resolution analog-to-digital converter of 14 bits or more, such that, it is unnecessary to separate the DC and pulsatile components of the oximeter signal prior to processing within the microprocessor.

摘要翻译： 公开了一种使用无创光学技术测量血氧饱和度的血氧计系统。 用两个不同波长的光照射患者的动脉血，并且通过所述动脉血液透过或反射的光的强度与组织的血氧饱和度相关。 该系统提供了使用14位或更多的高分辨率模拟 - 数字转换器在血氧计信号中避免过滤伪影的方式，使得不必在之前分离血氧计信号的DC和脉动分量 在微处理器内进行处理。

公开(公告)号：US5007423A

公开(公告)日：1991-04-16

申请号：US417209

申请日：1989-10-04

申请人： Ronald L. Branstetter ,  Jonathan P. Jaeb ,  Jeffrey M. Gabelmann

发明人： Ronald L. Branstetter ,  Jonathan P. Jaeb ,  Jeffrey M. Gabelmann

IPC分类号： A61B5/00

CPC分类号： A61B5/14551 ,  A61B5/1491

摘要： A system for measuring blood oxygen saturation uses a noninvasive optical technique. A patient's arterial blood is illuminated with light at two different wavelengths and the intensity of the reflected light is correlated with an oxygen saturation reference curve to determine the oxygen saturation of the patient's blood. The optical sensor includes one or more controlled heat sources which are used to maintain the patient's tissue at a predetermined temperature. Safety circuits are also provided in order to prevent thermal burns to a patient in the event of a system failure.

摘要翻译： 用于测量血氧饱和度的系统使用无创光学技术。 用两个不同波长的光照射患者的动脉血，并且反射光的强度与氧饱和度参考曲线相关联，以确定患者血液的氧饱和度。 光学传感器包括用于将患者组织保持在预定温度的一个或多个受控热源。 还提供了安全电路，以便在发生系统故障的情况下防止对患者的热灼伤。

公开(公告)号：US4880304A

公开(公告)日：1989-11-14

申请号：US33406

申请日：1987-04-01

申请人： Jonathan P. Jaeb ,  Dennis W. Gilstad ,  Ronald L. Branstetter

发明人： Jonathan P. Jaeb ,  Dennis W. Gilstad ,  Ronald L. Branstetter

IPC分类号： G01N21/27 ,  A61B5/00 ,  A61B5/145 ,  A61B5/1455 ,  G01N21/31 ,  G01N21/35

CPC分类号： A61B5/14552 ,  G01N21/3151 ,  G01N2021/3181

摘要： An improved optical sensor which has increased sensitivity and which is resistant to the effects of ambient light. In one embodiment of the invention, the sensor housing has a flat lower face with a central protrusion in which a plurality of light emitting diodes and an optical sensor are mounted. When the sensor is placed on the patient's tissue, the portion of the sensor face containing the LEDs and detector protrudes slightly into the tissue to provide improved optical coupling of the sensor to the skin. A light absorbing compliant material is attached to the perimeter of the sensor to reduce the effects of ambient light and to provide a cushion to minimize discomfort to the patient. In an alternate embodiment of the sensor, the LEDs and detector are mounted in a horizontal configuration substantially parallel to the surface of the tissue. The light produced by the LEDs is projected into a central chamber of the housing where the respective beams are combined and directed toward the tissue. In this emodiment, the desired combining of the beams can be achieved through the use of a set of mirrors or a prism. Various combinations of the improvements provided by each of the embodiments described above can be incorporated into either a transmission or backscatter optical sensor to provide a compact, sensitive optical sensor which is resistant to interference caused by ambient light.

摘要翻译： 一种改进的光学传感器，其具有增加的灵敏度并且抵抗环境光的影响。 在本发明的一个实施例中，传感器壳体具有平坦的下表面，其中安装有多个发光二极管和光学传感器。 当传感器放置在患者的组织上时，包含LED和检测器的传感器面的部分略微突出到组织中，以提供传感器与皮肤的改进的光耦合。 光吸收顺应性材料附着到传感器的周边以减少环境光的影响并提供缓冲垫以最小化对患者的不适。 在传感器的替代实施例中，LED和检测器以基本上平行于组织表面的水平配置安装。 由LED产生的光被投射到壳体的中心室中，其中各个光束被组合并指向组织。 在这种情况下，可以通过使用一组反射镜或棱镜来实现光束的期望组合。 上述每个实施例提供的改进的各种组合可以被并入传输或反向散射光学传感器中，以提供抵抗由环境光引起的干扰的紧凑的，灵敏的光学传感器。

公开(公告)号：US08075503B2

公开(公告)日：2011-12-13

申请号：US11656630

申请日：2007-01-23

申请人： Jonathan P. Jaeb

发明人： Jonathan P. Jaeb

IPC分类号： A61M35/00

CPC分类号： A61N7/00 ,  A61B17/320068 ,  A61F13/00068 ,  A61H23/0245 ,  A61M1/0058 ,  A61M1/0088 ,  A61M2205/058

摘要： A wound treatment system includes a distribution manifold, a reduced pressure source, a fluid delivery source, and an ultrasonic energy transducer. Reduced pressure and fluid delivery may be applied to the wound through the distribution manifold. The ultrasonic energy transducer is configured to deliver ultrasonic energy to the wound to debride the wound. The ultrasonic energy transducer may be either a piezoelectric transducer or a surface acoustic wave device. The ultrasonic energy transducer may be placed adjacent to the distribution manifold to deliver ultrasonic energy directly to the wound or may be coupled to an acoustically-conducting membrane positioned between the distribution manifold and the wound.

摘要翻译： 伤口治疗系统包括分配歧管，减压源，流体输送源和超声能量换能器。 减压和流体输送可以通过分配歧管施加到伤口。 超声能量换能器被配置为向伤口递送超声能量以清除伤口。 超声能量换能器可以是压电换能器或表面声波装置。 超声波能量换能器可以放置在分配歧管附近，以将超声波能量直接传递到伤口，或者可以连接到位于分配歧管和伤口之间的导电膜。

公开(公告)号：US20070239078A1

公开(公告)日：2007-10-11

申请号：US11656630

申请日：2007-01-23

申请人： Jonathan P. Jaeb

发明人： Jonathan P. Jaeb

IPC分类号： A61H1/00

CPC分类号： A61N7/00 ,  A61B17/320068 ,  A61F13/00068 ,  A61H23/0245 ,  A61M1/0058 ,  A61M1/0088 ,  A61M2205/058

摘要： A wound treatment system includes a distribution manifold, a reduced pressure source, a fluid delivery source, and an ultrasonic energy transducer. Reduced pressure and fluid delivery may be applied to the wound through the distribution manifold. The ultrasonic energy transducer is configured to deliver ultrasonic energy to the wound to debride the wound. The ultrasonic energy transducer may be either a piezoelectric transducer or a surface acoustic wave device. The ultrasonic energy transducer may be placed adjacent to the distribution manifold to deliver ultrasonic energy directly to the wound or may be coupled to an acoustically-conducting membrane positioned between the distribution manifold and the wound.

摘要翻译： 伤口治疗系统包括分配歧管，减压源，流体输送源和超声能量换能器。 减压和流体输送可以通过分配歧管施加到伤口。 超声能量换能器被配置为向伤口递送超声能量以清除伤口。 超声能量换能器可以是压电换能器或表面声波装置。 超声波能量换能器可以放置在分配歧管附近，以将超声波能量直接传递到伤口，或者可以连接到位于分配歧管和伤口之间的导电膜。

公开(公告)号：US4899760A

公开(公告)日：1990-02-13

申请号：US062781

申请日：1987-06-15

申请人： Jonathan P. Jaeb ,  Merle E. Converse

发明人： Jonathan P. Jaeb ,  Merle E. Converse

IPC分类号： A61B5/022 ,  A61B5/00 ,  A61B5/0428 ,  A61B5/145 ,  A61B5/1477

CPC分类号： A61B5/14551 ,  A61B5/0428 ,  Y10S128/901 ,  Y10S128/902

摘要： An improved biological signal detector which is extremely sensitive, yet resistant to the effects of high frequency noise. A multiplexed signal representation of a plurality biological signals is demultiplexed by a detector circuit comprising a plurality of switches each of which controls an individual storage network. A switch logic control circuit synchronizes the various switches to close during the time intervals corresponding to the pulse amplitudes representing the particular signal of interest. The amplitude of the alternating component of each of the biological signals is stored in one of the respective storage networks over a number of pulse time intervals. In the preferred embodiment, the storage networks of the detector each have a time constant which is purposely chosen to be substantially longer than the time interval of the pulses. The long time constant of the storage networks allows the detector circuit to track changes in amplitude which manifest themselves over a relatively large number of time intervals, but prevents the detection of high frequency noise signals which may be present during the sampling intervals.

摘要翻译： 一种改进的生物信号检测器，其极度敏感，但耐高频噪声的影响。 多个生物信号的复用信号表示由包括多个开关的检测器电路解复用，每个开关控制各个存储网络。 开关逻辑控制电路使各种开关在对应于表示感兴趣的特定信号的脉冲幅度的时间间隔期间同步闭合。 每个生物信号的交替分量的振幅通过多个脉冲时间间隔存储在相应的存储网络之一中。 在优选实施例中，检测器的存储网络各自具有时间常数，该时间常数被有意地选择为比脉冲的时间间隔更长。 存储网络的长时间常数允许检测器电路跟踪在相对较大数量的时间间隔上表现出来的幅度变化，但是防止在采样间隔期间可能存在的高频噪声信号的检测。