公开(公告)号：US4951097A

公开(公告)日：1990-08-21

申请号：US165058

申请日：1988-03-07

申请人： Shigeki Oguchi ,  Yasuhiro Uotani ,  Yoshio Hirano

发明人： Shigeki Oguchi ,  Yasuhiro Uotani ,  Yoshio Hirano

IPC分类号： A61B10/00 ,  A61B6/00 ,  G01J3/12 ,  G01J3/28 ,  G01N15/14 ,  G06T5/50

CPC分类号： G06T5/50 ,  G01J2003/1213 ,  G01J3/2823 ,  G01N2021/6439

摘要： A method for bone histomorphometry by using a non-decalcified bone specimen, comprising the steps of: (a) obtaining two pictures A and B by recording different chromatic light transmitted through a same region of said non-decalcified bone specimen or by recording different chromatic fluorescence from the region of said non-decalcified bone specimen; (b) detecting the strength (brightness) L.sub.An and L.sub.Bn of the corresponding image elements (pixels) An and Bn of said two pictures A and B; (c) determining the ratio L.sub.An /L.sub.Bn ; (d) performing the steps (b) and (c) on all corresponding image elements of said two pictures A and B; and (e) with regard to the ratio L.sub.An /L.sub.Bn, calculating and expressing areas of three components of bone, said three components of bone being a calcified bone area, an osteoid area, and a bone marrow area, in said non-decalcified bone specimen.

公开(公告)号：US4903203A

公开(公告)日：1990-02-20

申请号：US929308

申请日：1986-11-12

申请人： Gentaro Yamashita ,  Yasuhiro Uotani ,  Yoshio Hirano

发明人： Gentaro Yamashita ,  Yasuhiro Uotani ,  Yoshio Hirano

IPC分类号： G01N23/04

CPC分类号： G01N23/04

摘要： A method for evaluating cancellous bone from a density pattern of the cancellous bone obtained by irradiating the cancellous bone with a radiation wherein trabeculae of the cancellous bone are analyzed based on a power spectrum obtained by a Fourier transformation of the density pattern is provided.Furthermore, a method for evaluating cancellous bone from the density pattern of the cancellous bone obtained by irradiating the cancellous bone with radiation, wherein the density pattern is determined by irradiating the radiation substantially vertically against the main trabecula of the cancellous bone and the degree of the bone atrophy of the cancellous bone is evaluated by using the area (.SIGMA.GS) of the density pattern and/or the value (.SIGMA.GS/D) obtained by dividing the area (.SIGMA.GS) by the bone width (D) of the cancellous bone.

摘要翻译： 提供了一种基于通过密度图案的傅里叶变换获得的功率谱，从通过用放射线照射松质骨获得的松质骨的密度模式来评估松质骨的方法，其中松质骨的小梁被分析。 此外，从通过用放射线照射松质骨获得的松质骨的密度图案来评估松质骨的方法，其中所述密度图案通过基本上垂直于所述松质骨的主小梁照射所述辐射而确定， 通过使用密度图案的面积（SIGMA GS）和/或通过将面积（SIGMA GS）除以松质骨的骨宽度（D）而获得的值（SIGMA GS / D）来评估松质骨的骨萎缩 骨。

公开(公告)号：US4721112A

公开(公告)日：1988-01-26

申请号：US793387

申请日：1985-10-31

申请人： Yoshio Hirano ,  Yasuhiro Uotani

发明人： Yoshio Hirano ,  Yasuhiro Uotani

IPC分类号： G01N23/04 ,  A61B6/00 ,  A61B10/00 ,  G06T7/00

CPC分类号： A61B6/505 ,  G06T7/00

摘要： A method for evaluating bone comprising the steps of: (a) determining a bone pattern (i) by measuring the photodensity of an X-ray photograph from the long bone of a limb or (ii) by photon absorptiometry from the long bone of a limb; (b) smoothing and symmetrizing the bone pattern to modify the same; (c) determining at least one index selected from the group consisting of an index of the bone cortical width (MCI), a bone width (D), a maximum bone density (GSmax), a minimum bone density (GSmin), a bone mineral content (.SIGMA.GS), and an average bone density (.SIGMA.GS/D or .SIGMA.GS/D.sup.2); and (d) evaluating the bone based on the at least one index. The bone evaluation also can be carried out by determining a bone density distribution, from the modified bone pattern obtained above, by setting a bone model having an elliptic bone cross-sectional external shape, a zonate bone cortex, and a bone density decreasing portion in the inside of the bone cortex. The bone evaluation can further be carried out by first obtaining modified patterns in a plurality of portions of the bone at a constant distance and, then, by determining a bone density distribution in each portion from the modified bone pattern in each portion by setting the above-mentioned bone model in each portion. The bone density distribution in each portion is classified, by color, based on the density values, and the X-ray image or photon absorptiometry image is converted to the image of the bone density distribution.

摘要翻译： 一种用于评估骨骼的方法，包括以下步骤：（a）通过测量来自肢体的长骨的X射线照片的光密度来确定骨图（i），或（ii）通过光子吸收测定法从 肢; （b）平滑和对称骨骼图案以修改其骨骼图案; （c）确定选自骨皮质宽度（MCI）的指数，骨宽度（D），最大骨密度（GSmax），最小骨密度（GSmin），骨骼 矿物质含量（SIGMA GS）和平均骨密度（SIGMA GS / D或SIGMA GS / D2）; 和（d）基于所述至少一个指标来评估骨骼。 骨骼评价也可以通过根据上述获得的修改后的骨骼图来确定骨密度分布，通过将具有椭圆形骨横截面外形，骨骼骨皮质和骨密度降低部分的骨模型设定为 骨皮质的内部。 骨骼评价可以进一步通过首先在一定距离的骨骼的多个部分中获得改变的图案，然后通过设定上述方法从每个部分中通过修改的骨骼图案确定每个部分的骨密度分布 在每个部分中提到的骨骼模型。 通过颜色对每个部分的骨密度分布进行分类，基于密度值，并将X射线图像或光子吸收测定图像转换为骨密度分布的图像。

公开(公告)号：US5224035A

公开(公告)日：1993-06-29

申请号：US873900

申请日：1992-04-24

申请人： Gentaro Yamashita ,  Yasuhiro Uotani ,  Choju Aoki

发明人： Gentaro Yamashita ,  Yasuhiro Uotani ,  Choju Aoki

IPC分类号： A61B5/107 ,  G06F19/00

CPC分类号： A61B5/107 ,  A61B5/7264 ,  G06F19/321 ,  G06F19/3487

摘要： A method for judging deformation of a vertebral body includes the steps of measuring a central length (a), rear brim length (c), and front brim length (d) from a profile X-ray image of a vertebral body to be judged, determining ratios of c/d, a/c and a/d, and classifying deformation of the vertebral body to be judged by using indices, c, d, c/d, a/c and a/d. Furthermore, a method for judging deformation of a vertebral body, which comprises obtaining at least two indices by measuring a central length (a), vertebral body width (b), rear brim length (c), and front brim length (d) from a profile X-ray image of a vertebral body, analyzing these indices by a discriminant function, and classifying a deformation of the vertebral body from results of the analysis.

摘要翻译： 一种用于判断椎体变形的方法，包括以下步骤：从要判断的椎体的轮廓X射线图像测量中心长度（a），后缘长度（c）和前缘长度（d） 确定c / d，a / c和a / d的比例，并通过使用指标c，d，c / d，a / c和a / d来判断椎体的变形。 此外，一种用于判断椎体变形的方法，包括通过测量中心长度（a），椎体宽度（b），后边缘长度（c）和前缘长度（d）来获得至少两个指数，所述方法来自 椎体的轮廓X射线图像，通过判别函数分析这些指标，并根据分析结果对椎体的变形进行分类。