公开(公告)号：USRE39560E1

公开(公告)日：2007-04-10

申请号：US10766747

申请日：2004-01-28

申请人： Shigeo Morimoto ,  Takashi Adachi ,  Tohru Matsunaga ,  Masato Kashimura ,  Yoshiaki Watanabe ,  Kaoru Sota

发明人： Shigeo Morimoto ,  Takashi Adachi ,  Tohru Matsunaga ,  Masato Kashimura ,  Yoshiaki Watanabe ,  Kaoru Sota

IPC分类号： C07H1/00

CPC分类号： C07H17/08

摘要： Erythromycin A derivatives represented by the general formula wherein R1 is a 2-alkenyl group having 3 to 15 carbon atoms, an arylmethyl group, or an arylmethyl group substituted by 1 to 3 of a halogen atom, an alkoxy group 1 to 4 carbon atoms, a nitro group or an alkoxycarbonyl group having 2 to 6 carbon atoms, R2 is a substituted silyl group and R3 is a hydrogen atom or R2, are disclosed. These compounds are useful as intermediates of the anti-bacterial agents.

摘要翻译： 以一般形式表示的红霉素A衍生物

公开(公告)号：US4990602A

公开(公告)日：1991-02-05

申请号：US283387

申请日：1988-12-12

申请人： Shigeo Morimoto ,  Takashi Adachi ,  Tohru Matsunaga ,  Masato Kashimura ,  Toshifumi Asaka ,  Yoshiaki Watanabe ,  Kaoru Sota ,  Kazuto Sekiuchi

发明人： Shigeo Morimoto ,  Takashi Adachi ,  Tohru Matsunaga ,  Masato Kashimura ,  Toshifumi Asaka ,  Yoshiaki Watanabe ,  Kaoru Sota ,  Kazuto Sekiuchi

IPC分类号： C07H17/08

CPC分类号： C07H17/08

摘要： Erthromycin A derivatives represented by the general formula ##STR1## wherein R.sup.1 is a group of the formula R.sup.7 CH.sub.2 -- (wherein R.sup.7 is a hydrogen group or a lower alkyl group) or a group of the formula R.sup.8 O-- (wherein R.sup.8 is a lower alkyl group), R.sup.2 is R.sup.8, a cycloalkyl group, a phenyl group or an aralkyl group.), or R.sup.2 and R.sup.7 together form an alkylene group, R.sup.3 is a hydrogen atom, a lower alkyl group, a phenyl group or an aralkyl group, or R.sup.3 and R.sup.7 together form an alkylene group, or R.sup.2 and R.sup.3 together form an alkylene group, R.sup.4 is a lower alkyl group, R.sup.5 is a substituted silyl group, and R.sup.6 is a hydrogen atom or R.sup.5, are disclosed. These compounds are useful as intermediates for the synthesis of antibacterial agents.

公开(公告)号：US06342590B1

公开(公告)日：2002-01-29

申请号：US07869111

申请日：1992-04-14

申请人： Shigeo Morimoto ,  Takashi Adachi ,  Tohru Matsunaga ,  Masato Kashimura ,  Yoshiaki Watanabe ,  Kaoru Sota

发明人： Shigeo Morimoto ,  Takashi Adachi ,  Tohru Matsunaga ,  Masato Kashimura ,  Yoshiaki Watanabe ,  Kaoru Sota

IPC分类号： C07H100

CPC分类号： C07H17/08

摘要： Erythromycin A derivatives represented by the general formula wherein R1 is a 2-alkenyl group having 3 to 15 carbon atoms, an arylmethyl group, or an arylmethyl group substituted by 1 to 3 of a halogen atom, an alkoxy group 1 to 4 carbon atoms, a nitro group or an alkoxycarbonyl group having 2 to 6 carbon atoms, R2 is a substituted silyl group and R3 is a hydrogen atom or R2, are disclosed. These compounds are useful as intermediates of the anti-bacterial agents.

摘要翻译： 由通式化合物R1表示的红霉素A衍生物是具有3〜15个碳原子的2-烯基，芳基甲基或被1〜3个卤素原子取代的芳甲基，1〜4个碳原子的烷氧基， 硝基或碳原子数为2〜6的烷氧基羰基，R2为取代甲硅烷基，R3为氢原子或R2。 这些化合物可用作抗细菌剂的中间体。

公开(公告)号：US5852536A

公开(公告)日：1998-12-22

申请号：US818121

申请日：1997-03-14

申请人： Tohru Matsunaga ,  Naoyuki Kaneyama ,  Takehiko Saito ,  Masatoshi Hayakawa

发明人： Tohru Matsunaga ,  Naoyuki Kaneyama ,  Takehiko Saito ,  Masatoshi Hayakawa

IPC分类号： G11B5/133 ,  G11B5/187 ,  G11B5/193 ,  G11B33/08

CPC分类号： G11B5/1878 ,  G11B5/1871 ,  G11B5/193 ,  G11B33/08

摘要： Sliding noise characteristics can be considerably improved without degrading electromagnetic conversion characteristics and abrasion resistance characteristics in a recording/reproducing operation. A depth (H) of a contact width regulating groove (21) is set to be smaller than a contact width (W) of a magnetic recording medium sliding surface (a), and is set to a predetermined value of 25 .mu.m or more and 45 .mu.m or less. A depth (H) of the contact regulating groove is set to a predetermined value of 37.+-.12 .mu.m, the contact width (W) on the magnetic recording medium sliding surface (a) is set to a predetermined value of 55.+-.6 .mu.m, and a value (R) of a corner portion of the contact width regulating groove is set to a predetermined value of 16 .mu.m or less.

摘要翻译： 滑动噪声特性可以显着提高，而不会降低记录/再现操作中的电磁转换特性和耐磨性。 接触宽度调节槽（21）的深度（H）设定为小于磁记录介质滑动面（a）的接触宽度（W），并设定为25μm以上的规定值 45亩以下。 接触调节槽的深度（H）设定为37 +/-12μm的预定值，磁记录介质滑动面（a）上的接触宽度（W）被设定为预定值为55+ /-6μm，接触宽度调节槽的角部的值（R）设定为16μm以下的规定值。

公开(公告)号：US5089654A

公开(公告)日：1992-02-18

申请号：US562602

申请日：1990-08-03

申请人： Sadakazu Yokomori ,  Keiko Saijo ,  Tohru Matsunaga ,  Yoshimoto Nakashima ,  Katsuo Hatayama

发明人： Sadakazu Yokomori ,  Keiko Saijo ,  Tohru Matsunaga ,  Yoshimoto Nakashima ,  Katsuo Hatayama

IPC分类号： A61K31/19 ,  A61K31/12 ,  A61K31/215 ,  A61K31/22 ,  A61P1/04 ,  C07C45/51 ,  C07C45/74 ,  C07C49/82 ,  C07C49/84 ,  C07C59/00 ,  C07C59/90 ,  C07C69/712 ,  C07C69/738

CPC分类号： C07C69/712 ,  C07C45/513 ,  C07C45/74 ,  C07C49/84 ,  C07C59/90

摘要： Chalcone derivatives represented by the formula ##STR1## wherein R.sup.1 is a straight chain, branched chain or cyclic alkyl group having 4 to 15 carbon atoms or an alkenyl group having 3 to 15 carbon atoms, and occurs at the 2- or 4-position, R.sup.2 is a hydrogen atom, a straight or branched chain alkyl group having 1 to 3 carbon atoms, and X is a straight or branched chain alkylene group having 1 to 3 carbon atoms, are disclosed. These compounds have anti-ulcer effect, gastric mucosal protection effect and antisecretory effect.