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    Method and system for instant biopsy specimen analysis
    1.
    发明授权
    Method and system for instant biopsy specimen analysis 失效
    即时活检标本分析方法和系统

    公开(公告)号：US07018333B2

    公开(公告)日：2006-03-28

    申请号：US10466568

    申请日：2001-11-20

    申请人： Shih-Ping Wang ,  Tommy Earl Cupples ,  Xiangyong Cheng

    发明人： Shih-Ping Wang ,  Tommy Earl Cupples ,  Xiangyong Cheng

    IPC分类号： A61B8/00

    CPC分类号： G01S15/8993 ,  A61B8/0833 ,  A61B10/0096 ,  A61B2090/378 ,  G01N29/0609 ,  G01N29/223 ,  G01N29/28 ,  G01N2291/02466 ,  G01S7/52017

    摘要： An apparatus and related methods for ultrasound-assisted surgical removal of a tumor or other biological object from a patient, the tumor requiring complete removal such that no portion thereof remains inside the patient, is described. According to a preferred embodiment, a specimen containing the tumor is extracted from the patient and suspended in a container holding an acoustically conductive fluid. An ultrasound probe is brought into acoustic communication with the fluid and scans the specimen, preferably at an acoustic power setting higher than a maximum ultrasonic power permitted on live human tissue. Resulting two-dimensional and/or three-dimensional ultrasound images of the specimen, which have a higher quality due to the increased acoustic power of the scan, are viewed on an output display for examining whether any portion of the tumor comes into contact with a surface of the specimen. Preferably, the ultrasound images are segmented and processed by the ultrasound system in a manner that further assists in the determination of whether the specimen contains the entire tumor.

    摘要翻译： 描述了用于从患者超声辅助手术切除肿瘤或其他生物体的装置和相关方法，所述肿瘤需要完全去除，使得其中没有部分残留在患者体内。 根据优选实施方案，从患者中提取含有肿瘤的样本，并将其悬浮在容纳声导电液体的容器中。 将超声波探头与流体进行声学连通，并扫描样本，优选地在高于活体组织允许的最大超声功率的声功率设定。 在输出显示器上观察由于扫描增加的声功率而具有较高质量的样本的所得到的二维和/或三维超声图像，用于检查肿瘤的任何部分是否与 试样表面。 优选地，超声图像被分段和超声系统处理，以进一步有助于确定样本是否包含整个肿瘤的方式。

    THICK-SLICE ULTRASOUND IMAGES DERIVED FROM ULTRASONIC SCANS OF A CHESTWARDLY-COMPRESSED BREAST OF A SUPINE PATIENT
    2.
    发明申请
    THICK-SLICE ULTRASOUND IMAGES DERIVED FROM ULTRASONIC SCANS OF A CHESTWARDLY-COMPRESSED BREAST OF A SUPINE PATIENT 有权
    超声波超声波超声波扫描的厚度超大的超声波扫描仪

    公开(公告)号：US20110098566A1

    公开(公告)日：2011-04-28

    申请号：US12890374

    申请日：2010-09-24

    申请人： Wei ZHANG ,  Shih-Ping Wang ,  Jiayu Chen ,  Zengpin Yu ,  Tommy Earl Cupples ,  Thomas P. Neff ,  Michael E. Reed

    发明人： Wei ZHANG ,  Shih-Ping Wang ,  Jiayu Chen ,  Zengpin Yu ,  Tommy Earl Cupples ,  Thomas P. Neff ,  Michael E. Reed

    IPC分类号： A61B8/14 ,  G06T15/20

    CPC分类号： A61B8/5238 ,  A61B6/463 ,  A61B6/502 ,  A61B6/5247 ,  A61B6/563 ,  A61B8/0825 ,  A61B8/13 ,  A61B8/406 ,  A61B8/4281 ,  A61B8/4405 ,  A61B8/462 ,  A61B8/463 ,  A61B8/465 ,  A61B8/466 ,  A61B8/467 ,  A61B8/565

    摘要： Displaying breast ultrasound information on an interactive user interface is described, the user interface being useful in adjunctive ultrasound mammography environments and/or ultrasound-only mammography environments. Bilateral comparison is facilitated by a pairwise display of thick-slice images corresponding to analogous slab-like subvolumes in the left and right breasts. Coronal thick-slice imaging and convenient navigation on and among coronal thick-slice images is described. In one preferred embodiment, a nipple marker is displayed the coronal thick-slice image representing a projection of a nipple location thereupon. A convenient breast icon is also displayed including a cursor position indicator variably disposed thereon in a manner that reflects a relative position between the cursor and the nipple marker. Preferably, the breast icon is configured to at least roughly resemble a clock face, the center of the clock face representing the nipple marker location. Bookmark-centric and CAD-marker-centric navigation within and among thick-slice images is also described.

    摘要翻译： 描述了在交互式用户界面上显示乳房超声信息，用户界面在辅助超声乳腺X线照相术环境和/或仅超声乳腺X线照相术环境中有用。 通过成对显示对应于左乳房和右乳房中类似的板状子体积的双层比较来促进双边比较。 描述了冠状厚片成像和冠状厚片图像之间和之间方便的导航。 在一个优选实施例中，乳头标记被显示为表示其上的乳头位置的投影的冠状厚片图像。 还显示方便的胸部图标，包括以反映光标和乳头标记之间的相对位置的方式可变地设置在其上的光标位置指示器。 优选地，乳房图标被配置为至少大致类似于时钟面，时钟面的中心表示乳头标记位置。 还描述了厚片图像内和书签中心和CAD标记为中心的导航。

    Thick-slice ultrasound images derived from ultrasonic scans of a chestwardly-compressed breast of a supine patient
    3.
    发明授权
    Thick-slice ultrasound images derived from ultrasonic scans of a chestwardly-compressed breast of a supine patient 有权
    来自仰卧患者胸部压缩乳房超声扫描的厚片超声图像

    公开(公告)号：US08162833B2

    公开(公告)日：2012-04-24

    申请号：US12890374

    申请日：2010-09-24

    申请人： Wei Zhang ,  Shih-Ping Wang ,  Jiayu Chen ,  Zengpin Yu ,  Tommy Earl Cupples ,  Thomas P. Neff ,  Michael E. Reed

    发明人： Wei Zhang ,  Shih-Ping Wang ,  Jiayu Chen ,  Zengpin Yu ,  Tommy Earl Cupples ,  Thomas P. Neff ,  Michael E. Reed

    IPC分类号： A61B8/00

    CPC分类号： A61B8/5238 ,  A61B6/463 ,  A61B6/502 ,  A61B6/5247 ,  A61B6/563 ,  A61B8/0825 ,  A61B8/13 ,  A61B8/406 ,  A61B8/4281 ,  A61B8/4405 ,  A61B8/462 ,  A61B8/463 ,  A61B8/465 ,  A61B8/466 ,  A61B8/467 ,  A61B8/565

    摘要： Displaying breast ultrasound information on an interactive user interface is described, the user interface being useful in adjunctive ultrasound mammography environments and/or ultrasound-only mammography environments. Bilateral comparison is facilitated by a pairwise display of thick-slice images corresponding to analogous slab-like subvolumes in the left and right breasts. Coronal thick-slice imaging and convenient navigation on and among coronal thick-slice images is described. In one preferred embodiment, a nipple marker is displayed the coronal thick-slice image representing a projection of a nipple location thereupon. A convenient breast icon is also displayed including a cursor position indicator variably disposed thereon in a manner that reflects a relative position between the cursor and the nipple marker. Preferably, the breast icon is configured to at least roughly resemble a clock face, the center of the clock face representing the nipple marker location. Bookmark-centric and CAD-marker-centric navigation within and among thick-slice images is also described.

    摘要翻译： 描述了在交互式用户界面上显示乳房超声信息，用户界面在辅助超声乳腺X线照相术环境和/或仅超声乳腺X线照相术环境中有用。 通过成对显示对应于左乳房和右乳房中类似的板状子体积的双层比较来促进双边比较。 描述了冠状厚片成像和冠状厚片图像之间和之间方便的导航。 在一个优选实施例中，乳头标记被显示为表示其上的乳头位置的投影的冠状厚片图像。 还显示方便的胸部图标，包括以反映光标和乳头标记之间的相对位置的方式可变地设置在其上的光标位置指示器。 优选地，乳房图标被配置为至少大致类似于时钟面，时钟面的中心表示乳头标记位置。 还描述了厚片图像内和书签中心和CAD标记为中心的导航。

    Coronal and axial thick-slice ultrasound images derived from ultrasonic scans of a chestwardly-compressed breast
    4.
    发明授权
    Coronal and axial thick-slice ultrasound images derived from ultrasonic scans of a chestwardly-compressed breast 有权
    冠状和轴向厚片超声图像来自胸部压缩乳房的超声波扫描

    公开(公告)号：US07828733B2

    公开(公告)日：2010-11-09

    申请号：US12545201

    申请日：2009-08-21

    申请人： Wei Zhang ,  Shih-Ping Wang ,  Jiayu Chen ,  Zengpin Yu ,  Tommy Earl Cupples ,  Thomas P. Neff ,  Michael E. Reed

    发明人： Wei Zhang ,  Shih-Ping Wang ,  Jiayu Chen ,  Zengpin Yu ,  Tommy Earl Cupples ,  Thomas P. Neff ,  Michael E. Reed

    IPC分类号： A61B8/00

    CPC分类号： A61B8/5238 ,  A61B6/463 ,  A61B6/502 ,  A61B6/5247 ,  A61B6/563 ,  A61B8/0825 ,  A61B8/13 ,  A61B8/406 ,  A61B8/4281 ,  A61B8/4405 ,  A61B8/462 ,  A61B8/463 ,  A61B8/465 ,  A61B8/466 ,  A61B8/467 ,  A61B8/565

    摘要： Displaying breast ultrasound information on an interactive user interface is described, the user interface being useful in adjunctive ultrasound mammography environments and/or ultrasound-only mammography environments. Bilateral comparison is facilitated by a pairwise display of thick-slice images corresponding to analogous slab-like subvolumes in the left and right breasts. Coronal thick-slice imaging and convenient navigation on and among coronal thick-slice images is described. In one preferred embodiment, a nipple marker is displayed the coronal thick-slice image representing a projection of a nipple location thereupon. A convenient breast icon is also displayed including a cursor position indicator variably disposed thereon in a manner that reflects a relative position between the cursor and the nipple marker. Preferably, the breast icon is configured to at least roughly resemble a clock face, the center of the clock face representing the nipple marker location. Bookmark-centric and CAD-marker-centric navigation within and among thick-slice images is also described.

    摘要翻译： 描述了在交互式用户界面上显示乳房超声信息，用户界面在辅助超声乳腺X线照相术环境和/或仅超声乳腺X线照相术环境中有用。 通过成对显示对应于左乳房和右乳房中类似的板状子体积的双层比较来促进双边比较。 描述了冠状厚片成像和冠状厚片图像之间和之间方便的导航。 在一个优选实施例中，乳头标记被显示为表示其上的乳头位置的投影的冠状厚片图像。 还显示方便的胸部图标，包括以反映光标和乳头标记之间的相对位置的方式可变地设置在其上的光标位置指示器。 优选地，乳房图标被配置为至少大致类似于时钟面，时钟面的中心表示乳头标记位置。 还描述了厚片图像内和书签中心和CAD标记为中心的导航。

    Processing and displaying breast ultrasound information
    7.
    发明授权
    Processing and displaying breast ultrasound information 有权
    处理和显示乳房超声信息

    公开(公告)号：US07615008B2

    公开(公告)日：2009-11-10

    申请号：US10997293

    申请日：2004-11-23

    申请人： Wei Zhang ,  Shih-Ping Wang ,  Jiayu Chen ,  Zengpin Yu ,  Tommy Earl Cupples ,  Thomas P. Neff ,  Michael E. Reed

    发明人： Wei Zhang ,  Shih-Ping Wang ,  Jiayu Chen ,  Zengpin Yu ,  Tommy Earl Cupples ,  Thomas P. Neff ,  Michael E. Reed

    IPC分类号： A61B8/00

    CPC分类号： A61B8/5238 ,  A61B6/463 ,  A61B6/502 ,  A61B6/5247 ,  A61B6/563 ,  A61B8/0825 ,  A61B8/13 ,  A61B8/406 ,  A61B8/4281 ,  A61B8/4405 ,  A61B8/462 ,  A61B8/463 ,  A61B8/465 ,  A61B8/466 ,  A61B8/467 ,  A61B8/565

    摘要： Displaying breast ultrasound information on an interactive user interface is described, the user interface being useful in adjunctive ultrasound mammography environments and/or ultrasound-only mammography environments. Bilateral comparison is facilitated by a pairwise display of thick-slice images corresponding to analogous slab-like subvolumes in the left and right breasts. Coronal thick-slice imaging and convenient navigation on and among coronal thick-slice images is described. In one preferred embodiment, a nipple marker is displayed the coronal thick-slice image representing a projection of a nipple location thereupon. A convenient breast icon is also displayed including a cursor position indicator variably disposed thereon in a manner that reflects a relative position between the cursor and the nipple marker. Preferably, the breast icon is configured to at least roughly resemble a clock face, the center of the clock face representing the nipple marker location. Bookmark-centric and CAD-marker-centric navigation within and among thick-slice images is also described.

    摘要翻译： 描述了在交互式用户界面上显示乳房超声信息，用户界面在辅助超声乳腺X线照相术环境和/或仅超声乳腺X线照相术环境中有用。 通过成对显示对应于左乳房和右乳房中类似的板状子体积的双层比较来促进双边比较。 描述了冠状厚片成像和冠状厚片图像之间和之间方便的导航。 在一个优选实施例中，乳头标记被显示为表示其上的乳头位置的投影的冠状厚片图像。 还显示方便的胸部图标，包括以反映光标和乳头标记之间的相对位置的方式可变地设置在其上的光标位置指示器。 优选地，乳房图标配置为至少大致类似于时钟面，时钟面的中心表示乳头标记位置。 还描述了厚片图像内和书签中心和CAD标记为中心的导航。

    Full-field breast ultrasound system and architecture
    9.
    发明授权
    Full-field breast ultrasound system and architecture 有权
    全场乳房超声系统和体系结构

    公开(公告)号：US08317702B2

    公开(公告)日：2012-11-27

    申请号：US10560200

    申请日：2004-06-18

    申请人： Zengpin Yu ,  Danhua Zhao ,  Thomas P. Neff ,  Wei Zhang ,  Shih-Ping Wang

    发明人： Zengpin Yu ,  Danhua Zhao ,  Thomas P. Neff ,  Wei Zhang ,  Shih-Ping Wang

    IPC分类号： A61B8/00

    CPC分类号： A61B8/4477 ,  A61B8/0825 ,  A61B8/4281 ,  A61B8/4405 ,  A61B8/5238 ,  Y10T29/49005

    摘要： A modular, flexible architecture for offering full-field breast ultrasound (FFBU) functionality and general-purpose ultrasound functionality in a single system is described. A conventional, general-purpose ultrasound system (202) is modified with an FFBU toolkit to create a dual-capability ultrasound system (200), the dual-capability ultrasound system (200) being able to accommodate both general-purpose ultrasound functionality and FFBU functionality, using a single ultrasound engine (112). Among other advantages, real-world clinical environments may enjoy cost savings for initial system procurement, space savings on clinic floors, easier and less expensive system upgrades, and the ability to use a single system and user interface for both FFBU screening and for follow-up diagnosis, biopsy, etc. Among other advantages from an ultrasound manufacturer's perspective are the ability to quickly and/or more easily come to market with an FFBU-related offering by modifying their existing general-purpose ultrasound systems (202) with FFBU toolkits to quickly create dual-capability ultrasound systems (200).

    摘要翻译： 描述了在单个系统中提供全场乳房超声（FFBU）功能和通用超声功能的模块化，灵活的架构。 传统的通用超声系统（202）用FFBU工具包修改以创建双能力超声系统（200），双能力超声系统（200）能够容纳通用超声功能和FFBU 功能，使用单个超声引擎（112）。 除了其他优点之外，现实世界的临床环境可以节省初始系统采购成本，临床楼层节省空间，更便宜和更便宜的系统升级，以及使用单个系统和用户界面进行FFBU筛选和跟踪的功能， 诊断，活检等。超声波制造商的观点还有其他优点，即通过使用FFBU工具包修改现有的通用超声波系统（202），通过与FFBU相关的产品快速和/或更容易上市。 快速创建双功能超声系统（200）。

    BREAST ULTRASOUND SCANNING TEMPLATE
    10.
    发明申请
    BREAST ULTRASOUND SCANNING TEMPLATE 有权
    乳腺超声扫描模板

    公开(公告)号：US20120089026A1

    公开(公告)日：2012-04-12

    申请号：US13296023

    申请日：2011-11-14

    申请人： Shih-Ping Wang ,  Jiayu Chen ,  Douglas G. Summers

    发明人： Shih-Ping Wang ,  Jiayu Chen ,  Douglas G. Summers

    IPC分类号： A61B8/14

    CPC分类号： A61B8/0825 ,  A61B8/4218 ,  A61B8/4281 ,  A61B8/44 ,  A61B8/4405 ,  A61B8/4444 ,  A61B8/462 ,  A61B8/483 ,  A61B8/54

    摘要： Apparatus and related methods for facilitating volumetric ultrasonic scanning of a breast are described. In one preferred embodiment, a generally cone-shaped radial scanning template having a vertex and a wide opening angle is provided, the radial scanning template having a slot-like opening extending outward from the vertex through which an ultrasound transducer scans the breast as the radial scanning template is rotated. In another preferred embodiment, a flexible membrane for compressing a skin surface of the breast is provided, the flexible membrane being mounted on a mechanical assembly such as a roller assembly to form a slot-like opening through which an ultrasound transducer directly contacts the skin surface, the flexible membrane rising and falling relative to the skin surface but not moving laterally as the slot-like opening and ultrasound transducer move laterally across the compressed breast, whereby stabilization of the breast and direct transducer-skin contact are concurrently achieved.

    摘要翻译： 描述了用于促进乳房体积超声扫描的装置和相关方法。 在一个优选实施例中，提供了具有顶点和宽开口角度的大致锥形的径向扫描模板，该径向扫描模板具有从顶点向外延伸的狭缝状开口，超声波换能器通过该顶点径向扫描模具 扫描模板旋转。 在另一个优选实施例中，提供了用于压缩乳房皮肤表面的柔性膜，柔性膜被安装在诸如辊组件的机械组件上以形成狭缝状开口，超声波换能器通过该槽开口直接接触皮肤表面 ，柔性膜相对于皮肤表面上升和下降，但是当狭缝状开口和超声换能器横向压缩的乳房移动时横向移动，从而同时实现乳房的稳定和直接的换能器 - 皮肤接触。