公开(公告)号：US20030059896A1

公开(公告)日：2003-03-27

申请号：US10022832

申请日：2001-12-20

申请人： Shire BioChem Inc.

发明人： France Couture ,  Josee Hamel ,  Bernard R. Brodeur ,  Denis Martin ,  Pascal Brassard ,  Frederic Beaudoin ,  Paul Prefontaine

IPC分类号： G01N033/571 ,  C07H021/04 ,  C12P021/02 ,  C12N001/21 ,  C07K014/295 ,  C12N015/74

CPC分类号： C07K14/295 ,  A61K38/00 ,  A61K39/00 ,  C07K2319/00

摘要： Chlamydia pneumoniae polypeptides and polynucleotides encoding them are disclosed. Said polypeptides are antigenic and therefore useful components for the prophylaxis, diagnosis or therapy of Chlamydial infection in animals. Also disclosed are recombinant methods of producing the protein antigens as well as diagnostic assays for detecting Chlamydia bacterial infection, particularly C. pneumoniae.

摘要翻译： 披露肺炎衣原体多肽及编码它们的多核苷酸。 所述多肽是抗原性的，因此用于预防，诊断或治疗动物中衣原体感染的有用成分。 还公开了产生蛋白质抗原的重组方法以及用于检测衣原体细菌感染的诊断测定法，特别是肺炎衣原体。

公开(公告)号：US20030049271A1

公开(公告)日：2003-03-13

申请号：US10078531

申请日：2002-02-21

申请人： Shire BioChem Inc.

发明人： Denis Martin ,  Stephane Rioux ,  Bernard R. Brodeur ,  Josee Hamel ,  Patrick Rheault

IPC分类号： A61K039/02 ,  G01N033/554 ,  G01N033/569 ,  C07K014/315 ,  C07H021/04 ,  C12P021/02 ,  C12N001/21

CPC分类号： C07K14/315 ,  A61K38/00 ,  A61K39/00 ,  C07K2319/00

摘要： The present invention relates to antigens, more particularly antigens of Streptococcus pyogenes (also called group A Streptococcus (GAS)) bacterial pathogen which are useful as vaccine component for prophylaxis, therapy and/or diagnostic.