摘要:
Compounds of the general formula (I) or salts thereof and activators of PPAR&dgr; (peroxisome proliferator activated receptor &dgr;) containing the compounds or the salts as the active ingredient: wherein R1 and R2 each are hydrogen, C1-8 alkyl, an aryl or heterocyclic group which may be substituted, or the like; A is oxygen, sulfur, or the like; X1 and X2 are each a free valency, oxygen, S(O)p (wherein p is an integer of 0 to 2), C(═O), C(═O)NH, NHC(═O), CH═CH, or the like; Y is optionally substituted C1-8 alkylene; Z is oxygen or sulfur; R3 and R4 are each optionally substituted C1-8 alkyl; and R8 is hydrogen or C1-8 alkyl, with the proviso that when X1 is a free valency, X2 is not O or S(O)p, while when X1 is C(═O)NH, X2 is not a free valency.
摘要:
The invention relates to compounds of the following formula (I) or their salts: in which R1 represents OR4 or others, in which R4 is an alkyl group having 1-8 carbon atoms which may have a substituent or the like; R2 is halogen, nitro, cyano, carboxyl, or the like; R3 is hydrogen, halogen, hydroxyl, amino, carboxyl, or the like; X is NR11, oxygen, or sulfur, in which R11 is hydrogen, or an alkyl group having 1-8 carbon atom which may have a substituent; and each of Y and Z is CR12 or nitrogen, in which R12 has the same meaning as R3 above, and a xanthine oxidase inhibitor containing the compound as an active ingredient.
摘要翻译:本发明涉及下式(I)的化合物或其盐:其中R 1表示OR 4或其它,其中R 4 O / >是具有1-8个碳原子的可以具有取代基等的烷基; R 2是卤素,硝基,氰基,羧基等; R 3是氢,卤素,羟基,氨基,羧基等; X是NR 11,其中R 11是氢的氧或硫,或可以具有取代基的具有1-8个碳原子的烷基; Y和Z各自为CR 12或氮,其中R 12具有与上述R 3相同的含义,并且黄嘌呤氧化酶 含有该化合物作为活性成分的抑制剂。
摘要:
The invention relates to compounds of the following formula (I) or their salts: in which R1 represents OR4 or others, in which R4 is an alkyl group having 1-8 carbon atoms which may have a substituent or the like; R2 is halogen, nitro, cyano, carboxyl, or the like; R3 is hydrogen, halogen, hydroxyl, amino, carboxyl, or the like; X is NR11, oxygen, or sulfur, in which R11 is hydrogen, or an alkyl group having 1-8 carbon atom which may have a substituent; and each of Y and Z is CR12 or nitrogen, in which R12 has the same meaning as R3 above, and a xanthine oxidase inhibitor containing the compound as an active ingredient.
摘要翻译:本发明涉及下式(I)的化合物或其盐:其中R 1表示OR 4或其它,其中R 4 O / >是具有1-8个碳原子的可以具有取代基等的烷基; R 2是卤素,硝基,氰基,羧基等; R 3是氢,卤素,羟基,氨基,羧基等; X是NR 11,其中R 11是氢的氧或硫,或可以具有取代基的具有1-8个碳原子的烷基; Y和Z各自为CR 12或氮,其中R 12具有与上述R 3相同的含义,并且黄嘌呤氧化酶 含有该化合物作为活性成分的抑制剂。
摘要:
The invention relates to compounds of the following formula (I) or their salts: in which R1 represents OR4 or others, in which R4 is an alkyl group having 1-8 carbon atoms which may have a substituent or the like; R2 is halogen, nitro, cyano, carboxyl, or the like; R3 is hydrogen, halogen, hydroxyl, amino, carboxyl, or the like; X is NR11, oxygen, or sulfur, in which R11 is hydrogen, or an alkyl group having 1-8 carbon atom which may have a substituent; and each of Y and Z is CR12 or nitrogen, in which R12 has the same meaning as R3 above, and a xanthine oxidase inhibitor containing the compound as an active ingredient.
摘要翻译:本发明涉及下式(I)的化合物或其盐:其中R 1表示OR 4或其它,其中R 4 O / >是具有1-8个碳原子的可以具有取代基等的烷基; R 2是卤素,硝基,氰基,羧基等; R 3是氢,卤素,羟基,氨基,羧基等; X是NR 11,其中R 11是氢的氧或硫,或可以具有取代基的具有1-8个碳原子的烷基; Y和Z各自为CR 12或氮,其中R 12具有与上述R 3相同的含义,并且黄嘌呤氧化酶 含有该化合物作为活性成分的抑制剂。
摘要:
A compound represented by the following formula (I) is used as a xanthine oxidase inhibitor: in which R1 is phenyl or pyridyl each optionally having, as a substituent, C1-8 alkyl, C1-8 haloalkyl, C1-8 alkoxy, carboxyl, halogeno, hydroxyl, nitro, cyano, amino, etc.; R2 is cyano, nitro, etc.; X is oxygen, sulfur, etc.; and Y is sulfur, NH, etc.
摘要:
The invention relates to compounds of the following formula (I) or their salts: in which R1 is a group of phenyl, naphthyl, pyridyl or the like which may have a substituent such as an alkyl group having 1-8 carbon atoms, an alkoxy group having 1-8 carbon atoms, an alkoxycarbonyl group having 2-8 carbon atoms, carboxyl, halogen, hydroxyl, nitro, or cyano; R2 is cyano, nitro, or the like; R3 is hydroxyl or the like; X is oxygen, sulfur, or the like; and Y is oxygen or sulfur, and a xanthine oxidase inhibitor containing the compound.
摘要翻译:本发明涉及下式(I)化合物或其盐:其中R 1是苯基,萘基,吡啶基等可以具有取代基的基团,例如具有 1-8个碳原子,具有1-8个碳原子的烷氧基,具有2-8个碳原子的烷氧基羰基,羧基,卤素,羟基,硝基或氰基; R 2是氰基,硝基等; R 3是羟基等; X是氧,硫等; Y为氧或硫,含有该化合物的黄嘌呤氧化酶抑制剂。
摘要:
The invention relates to compounds of the following formula (I) or their salts: in which R1 is a group of phenyl, naphthyl, pyridyl or the like which may have a substituent such as an alkyl group having 1-8 carbon atoms, an alkoxy group having 1-8 carbon atoms, an alkoxycarbonyl group having 2-8 carbon atoms, carboxyl, halogen, hydroxyl, nitro, or cyano; R2 is cyano, nitro, or the like; R3 is hydroxyl or the like; X is oxygen, sulfur, or the like; and Y is oxygen or sulfur, and a xanthine oxidase inhibitor containing the compound.
摘要:
A touch panel system prevents an incorrect operation caused by an unintended contact of an object with a touch panel while suppressing a decline in sensitivity of detection of presence or absence of a touch on the touch panel. The touch panel system includes a touch invalidating section which, in a case where a specific point of a touch panel is continuously touched for a predetermined period of time, invalidates an instruction that is given, in accordance with the touch, to an electronic device including the touch panel.
摘要:
Live cells of a microorganism in a test sample are detected by the following steps: a) the step of treating the test sample with a topoisomerase poison and/or a DNA gyrase poison, b) the step of extracting DNA from the test sample, and amplifying a target region of the extracted DNA by PCR, and c) the step of analyzing an amplification product.
摘要:
The touch sensor system (1) includes: a touch panel (2) having a two-dimensional region (12) made up of a hand placing region (13) and a remainder region (14); a hand placing region processing section (3) for carrying out a process related to the hand placing region in accordance with a hand placing region touch signal corresponding to a touch to the hand placing region (13); and a plot input processing section (4) for carrying out a plot input process in accordance with a remainder region touch signal corresponding to a touch to the remainder region (14).