公开(公告)号：US5556862A

公开(公告)日：1996-09-17

申请号：US360630

申请日：1994-12-21

申请人： Shoichi Imai ,  Ken-ichi Mabuchi ,  Minoru Kawamura

发明人： Shoichi Imai ,  Ken-ichi Mabuchi ,  Minoru Kawamura

IPC分类号： C07D217/02 ,  A61K31/47 ,  A61K31/472 ,  A61K31/52 ,  A61K31/522 ,  A61P1/16 ,  A61P7/10 ,  A61P11/00 ,  A61P25/00 ,  A61P25/20 ,  A61P25/24 ,  A61P25/26 ,  A61P25/28 ,  A61P29/00 ,  A61P37/08 ,  A61P43/00 ,  C07D217/20 ,  C07D473/08

CPC分类号： A61K31/52 ,  A61K31/47

摘要： Pharmaceutical compositions containing an isoquinoline derivative exhibit an excellent inhibitory action to an isozyme of phosphodiesterase of the type IV (PDEIV). The active component of the pharmaceutical composition is an isoquinoline derivative which is represented by the general formula: ##STR1## wherein R is an ethoxy group, or which is a pharmaceutically-acceptable salt of a compound represented by said formula. The isoquinoline derivatives have an excellent inhibitory action which is highly specific to PDEIV. They are highly useful as pharmaceuticals such as antidepressive agents, tranquilizers, antidemential agents, antiinflammatory agents, antiallergic agents, antiasthmatic agents, liver-protecting agents, and diuretic agents.

摘要翻译： 含有异喹啉衍生物的药物组合物对IV型（PDEIV）的磷酸二酯酶的同功酶表现出优异的抑制作用。 药物组合物的活性成分是异喹啉衍生物，其由以下通式表示：其中R是乙氧基，或其是由所述式表示的化合物的药学上可接受的盐。 异喹啉衍生物具有优异的抑制作用，对PDEIV具有高度的特异性。 它们作为药物如抗抑郁药，镇静剂，抗抑郁剂，抗炎剂，抗过敏剂，止喘剂，肝保护剂和利尿剂是非常有用的。

公开(公告)号：US4921751A

公开(公告)日：1990-05-01

申请号：US41779

申请日：1987-04-23

申请人： Hideki Wakahara ,  Yoshihiro Matsuo ,  Minoru Kawamura

发明人： Hideki Wakahara ,  Yoshihiro Matsuo ,  Minoru Kawamura

IPC分类号： B32B27/18 ,  B32B5/02 ,  B32B5/08 ,  B32B27/04 ,  B32B27/12 ,  D02G1/18 ,  D03D15/04 ,  D04B1/14 ,  D04B1/20 ,  D04H11/04 ,  H05K9/00

CPC分类号： D04B1/20 ,  B32B27/12 ,  D02G1/18 ,  D04H11/04 ,  D10B2401/16 ,  Y10S428/922 ,  Y10T442/3065 ,  Y10T442/3854 ,  Y10T442/3862 ,  Y10T442/387 ,  Y10T442/3894 ,  Y10T442/3984 ,  Y10T442/438

摘要： A conductive fabric comprising conductive fibers and thermoplastic fibers with a higher heat shrinkage than that of said conductive fibers, said conductive fibers being crimped by heat shrinkage of said thermoplastic fibers. This invention also provides a conductive sheet or film comprising the conductive fabric and a base on which said conductive fabric is disposed, said conductive fabric and said base that are laminated together being fused into one piece by being heated at a temperature above the melting point of the thermoplastic fibers and melting said thermoplastic fibers.

摘要翻译： 一种包含导电纤维和热塑性纤维的导电织物，其热收缩率高于所述导电纤维，所述导电纤维通过所述热塑性纤维的热收缩而卷曲。 本发明还提供了一种导电片或薄膜，其包括导电织物和基底，所述导电织物设置在该基底上，层压在一起的所述导电织物和所述基底通过在高于熔点 热塑性纤维并熔化所述热塑性纤维。

公开(公告)号：US20090149658A1

公开(公告)日：2009-06-11

申请号：US12087591

申请日：2007-01-23

申请人： Ko Nakamura ,  Yoshitaka Nakazawa ,  Minoru Kawamura ,  Kunihiko Higashiura ,  Tomoshi Miura

发明人： Ko Nakamura ,  Yoshitaka Nakazawa ,  Minoru Kawamura ,  Kunihiko Higashiura ,  Tomoshi Miura

IPC分类号： C07D233/64

CPC分类号： C07D233/64 ,  A61K31/4172

摘要： The present invention is to provide a novel compound which is useful as an excellent analgesic agent. The present invention is to provide the novel histidine derivative having an excellent analgesic action and the like. The compound of the present invention is very useful as a pharmaceutical agent such as analgesics for the treatment of various kinds of acute or chronic pain diseases and of neuropathic pain diseases.

摘要翻译： 本发明提供一种作为优异止痛剂有用的新型化合物。 本发明提供具有优异止痛作用的新型组氨酸衍生物等。 本发明的化合物作为治疗各种急性或慢性疼痛疾病和神经性疼痛疾病的止​​痛剂等药剂是非常有用的。

公开(公告)号：US4817466A

公开(公告)日：1989-04-04

申请号：US930716

申请日：1986-11-13

申请人： Minoru Kawamura ,  Seiji Inoue

发明人： Minoru Kawamura ,  Seiji Inoue

IPC分类号： B60W10/04 ,  B60W10/06 ,  B60W10/10 ,  B63H21/21 ,  B63H21/22 ,  F02D11/10 ,  F02D29/02 ,  B60K41/06

CPC分类号： B63H21/213 ,  Y10T477/656 ,  Y10T477/675 ,  Y10T477/6805 ,  Y10T477/6934

摘要： A remote control system for a watercraft having a remotely positioned control device and a plurality of control device for operating the engine speed, transmission control and starter. The means for transmitting the signal from the control device to the controlled devices includes a computer that is programmed for moving the throttle of the engine to neutral when a shift is being made and for limiting the speed of the engine in reverse. In addition, and emergency deceleration device is provided for rapidly closing the throttle and shifting the transmission into the opposite direction for emergency deceleration. An improved starter arrangement is incorporated wherein the transmission is moved to neutral upon initiation of a starting sequence and the started is cranked for only a predetermined time interval to prevent overheating.

摘要翻译： 一种用于具有远程定位的控制装置的船舶遥控系统和用于操作发动机速度，变速器控制和起动器的多个控制装置。 用于将信号从控制装置传送到受控装置的装置包括一个计算机，该计算机被编程用于当发生换档时将发动机的节气门移动到空档并且相反地限制发动机的速度。 此外，还提供了紧急减速装置，用于快速关闭节气门并将变速器向相反方向移动以进行紧急减速。 引入了一种改进的起动器装置，其中在起动顺序开始时变速器被移动到空挡，并且起动仅在预定的时间间隔内被起动以防止过热。

公开(公告)号：US4747796A

公开(公告)日：1988-05-31

申请号：US919604

申请日：1986-10-14

申请人： Tomio Iwai ,  Minoru Kawamura

发明人： Tomio Iwai ,  Minoru Kawamura

IPC分类号： B63H20/14 ,  B63H23/04 ,  F16F15/12 ,  B63H21/28

CPC分类号： B63H23/04 ,  B63H21/28 ,  Y10T464/50

摘要： Several embodiments of coupling devices for marine outboard drives for providing a coupling between an engine output shaft and the outboard drive, drive shaft. Each embodiment employs as the coupling a first portion that provides a relatively resilient driving connection for absorbing low speed torque vibrations and a second more rigid driving connection for providing a more positive power transmission at high speeds and high loads. In some embodiments, the more resilient connection is provided by a spring which may comprise either a torsional spring or a torsional coil spring. In other embodiments, elastomeric elements provide the driving connection.

摘要翻译： 用于船用舷外驱动器的联接装置的几个实施例，用于在发动机输出轴和外侧驱动器，驱动轴之间提供联接。 每个实施例采用作为联接的第一部分，其提供用于吸收低速扭矩振动的相对弹性的驱动连接和用于在高速和高负载下提供更多正的动力传递的第二更刚性的驱动连接。 在一些实施例中，弹性连接由弹簧提供，该弹簧可包括扭转弹簧或扭转螺旋弹簧。 在其它实施例中，弹性元件提供驱动连接。

公开(公告)号：US08236844B2

公开(公告)日：2012-08-07

申请号：US12087591

申请日：2007-01-23

申请人： Ko Nakamura ,  Yoshitaka Nakazawa ,  Minoru Kawamura ,  Kunihiko Higashiura ,  Tomoshi Miura

发明人： Ko Nakamura ,  Yoshitaka Nakazawa ,  Minoru Kawamura ,  Kunihiko Higashiura ,  Tomoshi Miura

IPC分类号： C07D233/64 ,  A61K31/4172

CPC分类号： C07D233/64 ,  A61K31/4172

摘要： A novel histidine derivative represented by the following formula (I), and a pharmaceutically acceptable salt and hydrate thereof, useful as a pharmaceutical agent such as analgesics for the treatment of various kinds of acute or chronic pain diseases and of neuropathic pain diseases: wherein, R1 is hydrogen, alkyl having 1 to 6 carbon(s) or benzyl which may be substituted with alkyl having 1 to 4 carbon(s) or halogen; R2 is hydrogen or alkyl having 1 to 4 carbon(s); R3 and R4 are same or different and each is hydrogen, alkyl having 1 to 4 carbon(s) or phenyl which may be substituted with any one or two of alkyl having 1 to 6 carbon(s), alkoxy having 1 to 6 carbon(s), halogen, trifluoromethyl, nitro and cyano; and R5 is hydrogen or an alkyl group having 1 to 4 carbon(s).

摘要翻译： 由下式（I）表示的新型组氨酸衍生物及其药学上可接受的盐和水合物，可用作治疗各种急性或慢性疼痛疾病和神经性疼痛疾病的止​​痛药等药剂，其中， R1是氢，具有1至6个碳原子的烷基或可被具有1至4个碳原子的烷基或卤素取代的苄基; R2是氢或具有1至4个碳的烷基; R3和R4相同或不同，各自为氢，可具有1至4个碳的烷基或可被具有1至6个碳的烷基的任何一个或两个的烷基取代的苯基，具有1至6个碳的烷氧基（ s），卤素，三氟甲基，硝基和氰基; 并且R 5是氢或具有1至4个碳的烷基。

公开(公告)号：US4810216A

公开(公告)日：1989-03-07

申请号：US129851

申请日：1987-12-07

申请人： Minoru Kawamura

发明人： Minoru Kawamura

IPC分类号： B63H21/21 ,  B63H21/22

CPC分类号： B63H21/22

摘要： A remote control device for an outboard motor including a remotely positioned controller device that operates control devices carried by the outboard motor through optical fiber transmitted signals. The optical fibers are detachably connected to the controllers so as to permit removal of the controller. In addition, the controller is detachably supported within the associated watercraft so that it may be conveniently removed.

摘要翻译： 一种用于舷外马达的遥控装置，包括远程定位的控制器装置，其通过光纤传输信号操作由舷外马达承载的控制装置。 光纤可拆卸地连接到控制器，以便允许去除控制器。 此外，控制器可拆卸地支撑在相关联的船舶内，使得其可以方便地移除。