公开(公告)号：US08513271B2

公开(公告)日：2013-08-20

申请号：US12913966

申请日：2010-10-28

Applicant: Steven J. Coats ,  Haiyan Bian ,  Peter J. Connolly ,  Gilles Bignan ,  Chaozhong Cai ,  Scott L. Dax ,  Bart L. DeCorte ,  Shu-Chen Lin ,  Li Liu ,  Mark J. Macielag ,  Philip M. Pitis ,  Yue-Mei Zhang ,  Bin Zhu ,  Wei He

Inventor： Steven J. Coats ,  Haiyan Bian ,  Peter J. Connolly ,  Gilles Bignan ,  Chaozhong Cai ,  Scott L. Dax ,  Bart L. DeCorte ,  Shu-Chen Lin ,  Li Liu ,  Mark J. Macielag ,  Philip M. Pitis ,  Yue-Mei Zhang ,  Bin Zhu ,  Wei He

IPC: A01N43/54

CPC classification number: C07D239/47 ,  C07D401/04 ,  C07D401/12 ,  C07D401/14 ,  C07D403/04 ,  C07D403/12 ,  C07D403/14 ,  C07D405/14 ,  C07D409/14 ,  C07D413/14 ,  C07D417/14

Abstract: Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula I as follows: wherein R1, R2, R3, and L, A, and Ra are defined herein.

Abstract translation: 公开了用于治疗各种疾病，综合征，病症和障碍（包括疼痛）的化合物，组合物和方法。 这样的化合物由式I表示如下：其中R1，R2，R3和L，A和Ra在本文中定义。

公开(公告)号：USD685359S1

公开(公告)日：2013-07-02

申请号：US29409030

申请日：2011-12-20

Applicant: Shan-Yao Chen ,  Shu-Chen Lin ,  Jung-Pin Chen

Designer： Shan-Yao Chen ,  Shu-Chen Lin ,  Jung-Pin Chen

公开(公告)号：US08399454B2

公开(公告)日：2013-03-19

申请号：US12765254

申请日：2010-04-22

Applicant: Haiyan Bian ,  Kristen Chevalier ,  Jose Clemente ,  Pete Connolly ,  Chris Flores ,  Shu-Chen Lin ,  Li Liu ,  John Mabus ,  Mark Macielag ,  Mark McDonnell ,  Philip Pitis ,  Yue-Mei Zhang ,  Sui-Po Zhang ,  Bin Zhu

Inventor： Haiyan Bian ,  Kristen Chevalier ,  Jose Clemente ,  Pete Connolly ,  Chris Flores ,  Shu-Chen Lin ,  Li Liu ,  John Mabus ,  Mark Macielag ,  Mark McDonnell ,  Philip Pitis ,  Yue-Mei Zhang ,  Sui-Po Zhang ,  Bin Zhu

IPC: A61K31/496 ,  A61K31/55 ,  A61K31/5377 ,  C07D205/04 ,  C07D295/12 ,  C07D401/12 ,  C07D403/04 ,  C07D409/06 ,  C07D413/12

CPC classification number: C07D403/10 ,  C07D205/04 ,  C07D401/10 ,  C07D401/12 ,  C07D401/14 ,  C07D403/04 ,  C07D403/06 ,  C07D403/12 ,  C07D403/14 ,  C07D405/12 ,  C07D409/06 ,  C07D409/12 ,  C07D409/14 ,  C07D417/06 ,  C07D417/12 ,  C07D417/14 ,  C07D471/04 ,  C07D491/048 ,  C07D495/04

Abstract: Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula (I) as follows: wherein Y, Z, R1, and s are defined herein.

公开(公告)号：US08293750B2

公开(公告)日：2012-10-23

申请号：US13451652

申请日：2012-04-20

Applicant: Peter J. Connolly ,  Shu-Chen Lin ,  Mark J. Macielag ,  Yue-Mei Zhang

Inventor： Peter J. Connolly ,  Shu-Chen Lin ,  Mark J. Macielag ,  Yue-Mei Zhang

IPC: A61K31/4965

CPC classification number: C07D401/14 ,  C07D403/14

Abstract: Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula I as follows: wherein R1, R2, R3, L, X, and Y are defined herein.

公开(公告)号：US20120062082A1

公开(公告)日：2012-03-15

申请号：US13064083

申请日：2011-03-04

Applicant: Shu-Chen Lin

Inventor： Shu-Chen Lin

IPC: H05K5/02 ,  H05K13/00

CPC classification number: H05K5/0217 ,  B29C45/14311 ,  B29C45/14778 ,  B29C2045/14868 ,  B29K2705/00 ,  B29K2705/02

Abstract: A housing structure of electronic device and a manufacturing method thereof are provided. The housing structure of electronic device comprises a metal member and a plastic member. A surface of the metal member is formed with a plurality of micro anchored apertures. Each micro anchored aperture has an irregular inner wall. The plastic member is integrated on the surface of the metal member, wherein the plastic member extends in the micro anchored apertures and fully abutted and adhered on the irregular inner walls.

Abstract translation: 提供电子设备的壳体结构及其制造方法。 电子装置的壳体结构包括金属构件和塑料构件。 金属构件的表面形成有多个微锚定孔。 每个微型锚定孔具有不规则的内壁。 塑料构件整合在金属构件的表面上，其中塑料构件在微锚定孔中延伸并且完全邻接并粘附在不规则内壁上。

公开(公告)号：US07902227B2

公开(公告)日：2011-03-08

申请号：US12180641

申请日：2008-07-28

Applicant: Mark J. Macielag ,  Michele A. Weidner-Wells ,  Shu-Chen Lin

Inventor： Mark J. Macielag ,  Michele A. Weidner-Wells ,  Shu-Chen Lin

IPC: C07D215/00 ,  A01N43/42 ,  A61K31/47

CPC classification number: C07D498/04 ,  C07D519/00

Abstract: The present invention relates to C-7 isoxazolyl quinoline/naphthyridine derivatives useful as antimicrobial compounds, pharmaceutical compositions comprising said derivatives and the use of said derivatives and pharmaceutical compositions as antimicrobial agents against pathogenic microorganisms, particularly against resistant microbes.

Abstract translation: 本发明涉及可用作抗微生物化合物的C-7异恶唑基喹啉/萘啶衍生物，包含所述衍生物的药物组合物以及所述衍生物和药物组合物作为抗病原微生物，特别是抗性微生物的抗微生物剂的用途。

公开(公告)号：US20110015171A1

公开(公告)日：2011-01-20

申请号：US12765420

申请日：2010-04-22

Applicant: Haiyan BIAN ,  Kristen Chevalier ,  Jose Clemente ,  Pete Connolly ,  Chris Flores ,  Shu-Chen Lin ,  Li Liu ,  John Mabus ,  Mark Macielag ,  Mark McDonnell ,  Philip Pitis ,  Yue-Mei Zhang ,  Sui-Po Zhang ,  Bin Zhu

Inventor： Haiyan BIAN ,  Kristen Chevalier ,  Jose Clemente ,  Pete Connolly ,  Chris Flores ,  Shu-Chen Lin ,  Li Liu ,  John Mabus ,  Mark Macielag ,  Mark McDonnell ,  Philip Pitis ,  Yue-Mei Zhang ,  Sui-Po Zhang ,  Bin Zhu

IPC: A61K31/397 ,  C07D401/14 ,  C07D403/04 ,  C07D417/14 ,  C07D409/14 ,  A61P29/00 ,  A61P25/06 ,  A61P19/00 ,  A61P17/00

CPC classification number: C07D403/10 ,  C07D205/04 ,  C07D401/10 ,  C07D401/12 ,  C07D401/14 ,  C07D403/04 ,  C07D403/06 ,  C07D403/12 ,  C07D403/14 ,  C07D405/12 ,  C07D409/06 ,  C07D409/12 ,  C07D409/14 ,  C07D417/06 ,  C07D417/12 ,  C07D417/14 ,  C07D471/04 ,  C07D491/048 ,  C07D495/04

Abstract: Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula (I) as follows: wherein Y, Z, R1, and s are defined herein.

Abstract translation: 公开了用于治疗各种疾病，综合征，病症和障碍（包括疼痛）的化合物，组合物和方法。 这样的化合物由式（I）表示如下：其中Y，Z，R 1和S在本文中定义。

公开(公告)号：US20110015170A1

公开(公告)日：2011-01-20

申请号：US12765254

申请日：2010-04-22

Applicant: Haiyan BIAN ,  Kristen Chevalier ,  Jose Clemente ,  Pete Connolly ,  Chris Flores ,  Shu-Chen Lin ,  Li Liu ,  John Mabus ,  Mark Macielag ,  Mark McDonnell ,  Philip Pitis ,  Yue-Mei Zhang ,  Sui-Po Zhang ,  Bin Zhu

Inventor： Haiyan BIAN ,  Kristen Chevalier ,  Jose Clemente ,  Pete Connolly ,  Chris Flores ,  Shu-Chen Lin ,  Li Liu ,  John Mabus ,  Mark Macielag ,  Mark McDonnell ,  Philip Pitis ,  Yue-Mei Zhang ,  Sui-Po Zhang ,  Bin Zhu

IPC: A61K31/397 ,  C07D403/04 ,  C07D417/14 ,  C07D403/14 ,  A61P29/00 ,  A61P25/06 ,  A61P19/02 ,  A61P1/00

CPC classification number: C07D403/10 ,  C07D205/04 ,  C07D401/10 ,  C07D401/12 ,  C07D401/14 ,  C07D403/04 ,  C07D403/06 ,  C07D403/12 ,  C07D403/14 ,  C07D405/12 ,  C07D409/06 ,  C07D409/12 ,  C07D409/14 ,  C07D417/06 ,  C07D417/12 ,  C07D417/14 ,  C07D471/04 ,  C07D491/048 ,  C07D495/04

Abstract: Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula (I) as follows: wherein Y, Z, R1, and s are defined herein.

公开(公告)号：US20100324014A1

公开(公告)日：2010-12-23

申请号：US12765103

申请日：2010-04-22

Applicant: Haiyan BIAN ,  Kristen Chevalier ,  Jose Clemente ,  Pete Connolly ,  Chris Flores ,  Shu-Chen Lin ,  Li Liu ,  John Mabus ,  Mark Macielag ,  Mark McDonnell ,  Philip Pitis ,  Yue-Mei Zhang ,  Sui-Po Zhang ,  Bin Zhu

Inventor： Haiyan BIAN ,  Kristen Chevalier ,  Jose Clemente ,  Pete Connolly ,  Chris Flores ,  Shu-Chen Lin ,  Li Liu ,  John Mabus ,  Mark Macielag ,  Mark McDonnell ,  Philip Pitis ,  Yue-Mei Zhang ,  Sui-Po Zhang ,  Bin Zhu

IPC: A61K31/496 ,  C07D403/04 ,  C07D417/14 ,  A61K31/541 ,  A61P29/00

CPC classification number: C07D403/10 ,  C07D205/04 ,  C07D401/10 ,  C07D401/12 ,  C07D401/14 ,  C07D403/04 ,  C07D403/06 ,  C07D403/12 ,  C07D403/14 ,  C07D405/12 ,  C07D409/06 ,  C07D409/12 ,  C07D409/14 ,  C07D417/06 ,  C07D417/12 ,  C07D417/14 ,  C07D471/04 ,  C07D491/048 ,  C07D495/04

Abstract: Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula (I) as follows: wherein Y, Z, R1, and s are defined herein.

公开(公告)号：US20100324011A1

公开(公告)日：2010-12-23

申请号：US12765018

申请日：2010-04-22

Applicant: Haiyan Bian ,  Kristen Chevalier ,  Jose Clemente ,  Pete Connolly ,  Chris Flores ,  Shu-Chen Lin ,  Li Liu ,  John Mabus ,  Mark Macielag ,  Mark McDonnell ,  Philip Pitis ,  Yue-Mei Zhang ,  Sui-Po Zhang ,  Bin Zhu

Inventor： Haiyan Bian ,  Kristen Chevalier ,  Jose Clemente ,  Pete Connolly ,  Chris Flores ,  Shu-Chen Lin ,  Li Liu ,  John Mabus ,  Mark Macielag ,  Mark McDonnell ,  Philip Pitis ,  Yue-Mei Zhang ,  Sui-Po Zhang ,  Bin Zhu

IPC: A61K31/496 ,  C07D403/04 ,  C07D417/14 ,  C07D409/14 ,  C07D401/14 ,  C07D403/14 ,  A61P29/00

CPC classification number: C07D403/10 ,  C07D205/04 ,  C07D401/10 ,  C07D401/12 ,  C07D401/14 ,  C07D403/04 ,  C07D403/06 ,  C07D403/12 ,  C07D403/14 ,  C07D405/12 ,  C07D409/06 ,  C07D409/12 ,  C07D409/14 ,  C07D417/06 ,  C07D417/12 ,  C07D417/14 ,  C07D471/04 ,  C07D491/048 ,  C07D495/04

Abstract: Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula (I) as follows: wherein Y, Z, R1, and s are defined herein.