TEMPERATURE-, PH- OR SALT CONCENTRATION-SENSITIVE SEPARATION MATERIAL AND USE THEREOF
    3.
    发明申请
    TEMPERATURE-, PH- OR SALT CONCENTRATION-SENSITIVE SEPARATION MATERIAL AND USE THEREOF 有权
    温度,pH或盐浓度敏感性分离材料及其用途

    公开(公告)号:US20130012597A1

    公开(公告)日:2013-01-10

    申请号:US13636436

    申请日:2011-03-22

    摘要: The present invention provides a UCST-type thermoresponsive polymer compound which responds to a temperature under physiological conditions and has biofunctionality, and various uses thereof as a thermoresponsive material. Specifically, the invention provides a thermoresponsive material containing, as an active ingredient, a polymer compound represented by Formula (I) below or an addition salt thereof, the thermoresponsive material having an upper critical solution temperature in the range of 5 to 50° C. in an aqueous solution with a salt concentration of at least 1 mM and a pH in the range of 3 to 10.5: wherein m represents an integer of 10 or more; n represents a number satisfying 0.4≦n≦1; R1 represents hydrogen or succinyl; and R2 represents carbamoyl.

    摘要翻译: 本发明提供一种在生理条件下对温度有响应并具有生物功能性的UCST型热反应性高分子化合物及其各种用途作为热反应性材料。 具体地说,本发明提供一种热反应性材料,该材料含有作为有效成分的下式(Ⅰ)表示的高分子化合物或其加成盐,该热敏材料具有上限临界溶解温度在5〜50℃的范围内。 在盐浓度为至少1mM,pH在3至10.5范围内的水溶液中:其中m表示10或更大的整数; n表示满足0.4≦̸ n≦̸ 1; R1代表氢或琥珀酰基; R2代表氨基甲酰基。