公开(公告)号：US12054506B2

公开(公告)日：2024-08-06

申请号：US17698283

申请日：2022-03-18

Applicant: Singular Genomics Systems, Inc.

Inventor： Ronald Graham ,  Zachary Terranova

IPC: C07F9/6521

CPC classification number: C07F9/6521

Abstract: Disclosed herein, inter alia, are novel reducing agents having the general formula




and methods of use thereof.

公开(公告)号：US11851687B2

公开(公告)日：2023-12-26

申请号：US17207387

申请日：2021-03-19

Applicant: Singular Genomics Systems, Inc.

Inventor： Souad Naji ,  Eli N. Glezer ,  Youngjin Cho ,  Zachary Terranova ,  Abrehet Abdu

IPC: C12N9/12 ,  C12N15/63 ,  C12Q1/68 ,  C12Q1/6874

CPC classification number: C12N9/1252 ,  C12N15/63 ,  C12Q1/6874 ,  C12Y207/07007

Abstract: Provided herein are modified Archaeal family B polymerases derived from species of the Archaeal microorganism Pyrococcus that exhibit improved incorporation of nucleotide analogues utilized in DNA sequencing.

公开(公告)号：US20240294887A1

公开(公告)日：2024-09-05

申请号：US18659585

申请日：2024-05-09

Applicant: Singular Genomics Systems, Inc.

Inventor： Souad Naji ,  Alexander Sevy ,  Jason Cellitti ,  Eli N. Glezer ,  Bruna Krebs Kutche ,  Zachary Terranova ,  Sumit Handa

IPC: C12N9/12 ,  C12Q1/6844

CPC classification number: C12N9/1252 ,  C12Q1/6844 ,  C12Y207/07007

Abstract: Disclosed herein, inter alia, are mutant enzymes, kits, and methods of use thereof.

公开(公告)号：US20230119408A1

公开(公告)日：2023-04-20

申请号：US17887289

申请日：2022-08-12

Applicant: Singular Genomics Systems, Inc.

Inventor： Ronald Graham ,  Surya Adhikari ,  Ada Tong ,  Zachary Terranova

IPC: C12Q1/6874 ,  C07H19/10

Abstract: Disclosed herein, inter alia, are compounds, modified nucleotides, compositions, and methods of using the same.

公开(公告)号：US20230002436A1

公开(公告)日：2023-01-05

申请号：US17365361

申请日：2021-07-01

Applicant: Singular Genomics Systems, Inc.

Inventor： Ronald Graham ,  Surya Adhikari ,  Rodrigo Rodriguez ,  Zachary Terranova

IPC: C07H19/10 ,  C07H19/14 ,  C12Q1/6869 ,  C12N9/12

Abstract: Disclosed herein, inter alia, are compounds, modified nucleotides, compositions, and methods of using the same.

公开(公告)号：US12227774B2

公开(公告)日：2025-02-18

申请号：US18659585

申请日：2024-05-09

Applicant: Singular Genomics Systems, Inc.

Inventor： Souad Naji ,  Alexander Sevy ,  Jason Cellitti ,  Eli N. Glezer ,  Bruna Krebs Kutche ,  Zachary Terranova ,  Sumit Handa

IPC: C12N9/12 ,  C12Q1/6844

Abstract: Disclosed herein, inter alia, are mutant enzymes, kits, and methods of use thereof.

公开(公告)号：US11891633B2

公开(公告)日：2024-02-06

申请号：US17209043

申请日：2021-03-22

Applicant: Singular Genomics Systems, Inc.

Inventor： Souad Naji ,  Eli N. Glezer ,  Youngjin Cho ,  Zachary Terranova ,  Abrehet Abdu

IPC: C12N9/12 ,  C12N15/63 ,  C12Q1/68 ,  C12Q1/6874

CPC classification number: C12N9/1252 ,  C12N15/63 ,  C12Q1/6874 ,  C12Y207/07007

Abstract: Provided herein are modified Archaeal family B polymerases derived from species of the Archaeal microorganism Pyrococcus that exhibit improved incorporation of nucleotide analogues utilized in DNA sequencing.

公开(公告)号：US20220161251A1

公开(公告)日：2022-05-26

申请号：US17531488

申请日：2021-11-19

Applicant: Singular Genomics Systems, Inc.

Inventor： Andrew Spaventa ,  Christian Berrios ,  Eli N. Glezer ,  Zachary Terranova

IPC: B01L3/00 ,  G01N33/483 ,  G01N33/487 ,  G01N33/53 ,  B64C39/02

Abstract: Disclosed herein, inter alfa, are systems and methods for contactless evaluation of a biological sample.

公开(公告)号：US11174281B1

公开(公告)日：2021-11-16

申请号：US17238922

申请日：2021-04-23

Applicant: Singular Genomics Systems, Inc.

Inventor： Ronald Graham ,  Surya Adhikari ,  Rodrigo Rodriguez ,  Zachary Terranova

IPC: C07H19/10 ,  C07H19/14 ,  C12N9/12 ,  C12Q1/6869

Abstract: Disclosed herein, inter alia, are compounds, modified nucleotides, compositions, and methods of using the same.

公开(公告)号：US20240368202A1

公开(公告)日：2024-11-07

申请号：US18752325

申请日：2024-06-24

Applicant: Singular Genomics Systems, Inc.

Inventor： Ronald Graham ,  Zachary Terranova

IPC: C07F9/6521

Abstract: Disclosed herein, inter alia, are reducing agents and methods of use thereof.