公开(公告)号：US20080221582A1

公开(公告)日：2008-09-11

申请号：US12041827

申请日：2008-03-04

申请人： Son Gia ,  Ajit Nair ,  Andrew Huffmaster ,  Jeffrey Lee

发明人： Son Gia ,  Ajit Nair ,  Andrew Huffmaster ,  Jeffrey Lee

IPC分类号： A61B17/58

CPC分类号： A61B17/221 ,  A61B2017/00349 ,  A61B2017/00809 ,  A61B2017/22034 ,  A61B2017/22035 ,  A61F2002/9528

摘要： A removal tool for an implanted device, including pulmonary stents, occlusive devices, valved devices, and flow-restrictive devices, is provided. The removal tool includes an elongate tube having a central passage, a slideable inner member within the passage, and a coupling member disposed on the distal end of the inner member. The coupling member of the removal tool includes a distal tip configured to pierce a membrane of the implanted device. The coupling member also includes a coil or a hook configured to engage a support element of the implanted device. A method of removing implanted devices is also provided. A removal tool is placed adjacent to the device, the distal end of the tool is moved to pierce its membrane, a portion of the tool engages the support member, and the distal end of the tool is retracted along with the implanted device.

摘要翻译： 提供了用于植入装置的移除工具，包括肺支架，闭塞装置，带瓣装置和流动限制装置。 移除工具包括细长管，其具有中心通道，通道内的可滑动内部构件以及设置在内部构件的远端上的联接构件。 去除工具的联接构件包括构造成刺穿植入装置的膜的远侧末端。 联接构件还包括构造成接合植入装置的支撑元件的线圈或钩。 还提供了一种去除植入装置的方法。 移除工具邻近装置放置，工具的远端移动以刺穿其膜，工具的一部分与支撑构件接合，并且工具的远端与植入装置一起缩回。

公开(公告)号：US20080221703A1

公开(公告)日：2008-09-11

申请号：US12043404

申请日：2008-03-06

申请人： LIKE QUE ,  Hoang Nguyen ,  Son Gia ,  Ajitkumar Nair ,  Roger Farnholtz ,  George Surjan ,  Andrew Huffmaster ,  Jeffrey Lee

发明人： LIKE QUE ,  Hoang Nguyen ,  Son Gia ,  Ajitkumar Nair ,  Roger Farnholtz ,  George Surjan ,  Andrew Huffmaster ,  Jeffrey Lee

IPC分类号： A61F2/04 ,  B65D81/18

CPC分类号： A61B17/12022 ,  A61B17/12104 ,  A61B17/12172 ,  A61B50/30 ,  A61B2017/0053 ,  A61B2017/00809 ,  A61B2017/00867 ,  A61B2017/12054 ,  A61F2/04 ,  A61F2/2436 ,  A61F2002/043 ,  A61F2002/9522

摘要： Devices for loading a collapsible implant onto a delivery catheter. In one aspect, a loading device comprises an outer tubular structure and an inner tubular structure. The outer tubular structure comprises a narrowing passage configured to receive a catheter at one end and a collapsible implant at another end. The inner tubular structure is configured to move slidably and co-axially within the outer tubular structure. The inner tubular structure comprises a carrier pin configured to move within the narrowing passage as the inner tubular structure slides into the outer tubular structure. The sliding of the inner tubular structure into the outer tubular structure causes an implant mounted on the carrier pin to collapse as the implant moves through the narrowing passage and into the distal end of a catheter. In an optional aspect, the outer tubular structure further comprises a grasper to stabilize the catheter for receipt of the collapsible implant, and the internal diameter of the inner tubular structure varies to cause the grasper to first contract and stabilize the catheter, and then expand and release the catheter, as the grasper moves into the inner tubular structure.

摘要翻译： 用于将可折叠植入物装载到输送导管上的装置。 在一个方面，装载装置包括外部管状结构和内部管状结构。 外部管状结构包括被配置为在一端接收导管并在另一端容纳可折叠植入物的狭窄通道。 内部管状结构构造成在外部管状结构内可滑动地和同轴地移动。 内部管状结构包括承载销，其构造成随着内部管状结构滑入外部管状结构而在变窄的通道内移动。 内部管状结构滑动到外部管状结构中，当植入物移动通过变窄的通道并进入导管的远端时，安装在承载销上的植入物塌陷。 在可选方面，外部管状结构还包括抓紧器，用于稳定导管以接收可折叠植入物，并且内部管状结构的内径变化，使得抓紧器首先收缩和稳定导管，然后膨胀和 释放导管，因为抓紧器移动到内部管状结构中。

公开(公告)号：US08100959B2

公开(公告)日：2012-01-24

申请号：US12043404

申请日：2008-03-06

申请人： Like Que ,  Hoang Nguyen ,  Son Gia ,  Ajitkumar Nair ,  Roger Farnholtz ,  George Surjan ,  Andrew Huffmaster ,  Jeffrey Lee

发明人： Like Que ,  Hoang Nguyen ,  Son Gia ,  Ajitkumar Nair ,  Roger Farnholtz ,  George Surjan ,  Andrew Huffmaster ,  Jeffrey Lee

IPC分类号： A61F2/06

CPC分类号： A61B17/12022 ,  A61B17/12104 ,  A61B17/12172 ,  A61B50/30 ,  A61B2017/0053 ,  A61B2017/00809 ,  A61B2017/00867 ,  A61B2017/12054 ,  A61F2/04 ,  A61F2/2436 ,  A61F2002/043 ,  A61F2002/9522

摘要： Devices for loading a collapsible implant onto a delivery catheter. In one aspect, a loading device comprises an outer tubular structure and an inner tubular structure. The outer tubular structure comprises a narrowing passage configured to receive a catheter at one end and a collapsible implant at another end. The inner tubular structure is configured to move slidably and co-axially within the outer tubular structure. The inner tubular structure comprises a carrier pin configured to move within the narrowing passage as the inner tubular structure slides into the outer tubular structure. The sliding of the inner tubular structure into the outer tubular structure causes an implant mounted on the carrier pin to collapse as the implant moves through the narrowing passage and into the distal end of a catheter. In an optional aspect, the outer tubular structure further comprises a grasper to stabilize the catheter for receipt of the collapsible implant, and the internal diameter of the inner tubular structure varies to cause the grasper to first contract and stabilize the catheter, and then expand and release the catheter, as the grasper moves into the inner tubular structure.

摘要翻译： 用于将可折叠植入物装载到输送导管上的装置。 在一个方面，装载装置包括外部管状结构和内部管状结构。 外部管状结构包括被配置为在一端接收导管并在另一端容纳可折叠植入物的狭窄通道。 内部管状结构构造成在外部管状结构内可滑动地和同轴地移动。 内部管状结构包括承载销，其构造成随着内部管状结构滑入外部管状结构而在变窄的通道内移动。 内部管状结构滑动到外部管状结构中，当植入物移动通过变窄的通道并进入导管的远端时，安装在承载销上的植入物塌陷。 在可选方面，外部管状结构还包括抓紧器，用于稳定导管以接收可折叠植入物，并且内部管状结构的内径变化，使得抓紧器首先收缩和稳定导管，然后膨胀和 释放导管，因为抓紧器移动到内部管状结构中。

公开(公告)号：US08967136B2

公开(公告)日：2015-03-03

申请号：US12904714

申请日：2010-10-14

申请人： Jeffrey Lee

发明人： Jeffrey Lee

IPC分类号： F24J2/30 ,  F24J2/32 ,  F24J2/05 ,  F28D15/02

CPC分类号： F24S10/90 ,  F24S10/30 ,  F24S10/45 ,  F28D15/0266 ,  F28D15/0275 ,  Y02E10/44

摘要： A solar energy collecting system comprises a manifold defining a closed fluid passage between a condensation point and a heating point. The manifold includes a plurality of heat exchange members configured to be in heat exchange relationship with the fluid passage at the heating point, and a heat sink at the condensation point. A plurality of solar energy collector members extend from and operably connect to the heat exchange members of the manifold. The solar energy collector members collect solar energy and transform it into heat energy. Heat energy is transferred from the solar energy collector members to the heat exchange members and to a fluid in the passage in the manifold at the heating point so as to heat the fluid into a vapor. The fluid is circulated in heat exchange relationship to the condensation point where heat energy is transferred to the heat sink so as to cool the fluid to a liquid. The fluid repeatedly cycles between a vaporized state at the heat exchange members and a liquefied state at the condensation point.

摘要翻译： 太阳能收集系统包括限定在冷凝点和加热点之间的封闭流体通道的歧管。 歧管包括构造成与加热点处的流体通道处于热交换关系的多个热交换构件，以及在冷凝点处的散热器。 多个太阳能收集器构件从歧管的热交换构件延伸并且可操作地连接到歧管的热交换构件。 太阳能收集器收集太阳能并将其转化为热能。 热能从太阳能收集器构件传递到热交换构件，并且在加热点处的歧管中的通道中的流体被转移，以将流体加热成蒸气。 流体以热能传递到散热器的冷凝点与热交换关系循环，以将流体冷却至液体。 流体在热交换构件的蒸发状态和冷凝点处的液化状态之间重复循环。

公开(公告)号：US20100316990A1

公开(公告)日：2010-12-16

申请号：US12745404

申请日：2009-01-16

申请人： William Dynan ,  Hilal Arnouk ,  Mark Merkley ,  Jeffrey Lee ,  Daron Ferris ,  Hubert Stoppler ,  Robert H. Podolsky

发明人： William Dynan ,  Hilal Arnouk ,  Mark Merkley ,  Jeffrey Lee ,  Daron Ferris ,  Hubert Stoppler ,  Robert H. Podolsky

IPC分类号： C12Q1/70 ,  C12Q1/02 ,  C12Q1/26

CPC分类号： G01N33/57411

摘要： Biomarkers that correlate with progression to neoplasia in human papillomavirus (HPV) induced cancer, for example cervical cancer have been identified. These biomarkers can be used to diagnosis or assist in the diagnosis of HPV-induced cancer. They can also be used to increase the positive predictive value of current screening modalities. In addition, they can provide insights into the biology of HPV-induced cancer and thus provide leads for the development of nonsurgical therapies. Exemplary biomarkers include cornulin, PA28 β, DJ-1, actin, transthyretin, HSPB1, CV intracellular channel 1, cytokeratin 8, transferrin, Hsρβ6 (HSP20), aflatoxin reductase, α2 type I collagen, creatine kinase B, cytokeratin 13 GST π, PA28 α, Manganese SOD, lamin A/C, serpin B1 (elastase inhibitor), serpin B3 (SCAA1), cytokeratin 10, cytokeratin 6A, and trp-tRNA synthetase. Preferred biomarkers for HPV-induced cancer include cornulin, DJ-1, PA28 α, and PA28 β, trp-tRNA synthetase, HSPβ6, creatine kinase B, aflatoxin reductase, GST π, transthyretin, transferrin, α2-type 1 collagen, and combinations thereof.

摘要翻译： 与人乳头状瘤病毒（HPV）诱导的癌症（例如宫颈癌）发展相关的生物标志物已被鉴定。 这些生物标志物可用于诊断或协助HPV诱导的癌症的诊断。 它们也可用于增加当前筛选模式的阳性预测值。 此外，他们可以深入了解HPV诱导的癌症的生物学，从而为非手术疗法的发展提供依据。 示例性生物标志物包括玉米蛋白，PA28和bgr，DJ-1，肌动蛋白，转甲状腺素蛋白，HSPB1，CV细胞内通道1，细胞角蛋白8，转铁蛋白，Hs＆rgr; 6（HSP20），黄曲霉毒素还原酶，α2I型胶原，肌酸激酶B， 细胞角蛋白13 GST＆pgr;PA28α，锰SOD，lamin A / C，丝氨酸蛋白酶B1（弹性蛋白酶抑制剂），丝氨酸蛋白酶B3（SCAA1），细胞角蛋白10，细胞角蛋白6A和trp-tRNA合成酶。 HPV诱导的癌症的优选生物标志物包括玉米蛋白，DJ-1，PA28α和PA28＆bgr; trp-tRNA合成酶，HSP＆bgr; 6，肌酸激酶B，黄曲霉毒素还原酶，GST＆pgr;转甲状腺素蛋白，转铁蛋白，α2型1 胶原及其组合。

公开(公告)号：US20080052894A1

公开(公告)日：2008-03-06

申请号：US11936146

申请日：2007-11-07

申请人： Travis Thompson ,  Jeffrey Lee ,  Stephen Doubler ,  Robert Giuliani ,  James McGregor

发明人： Travis Thompson ,  Jeffrey Lee ,  Stephen Doubler ,  Robert Giuliani ,  James McGregor

IPC分类号： B23P13/04

CPC分类号： B23D41/06 ,  B23D37/10 ,  B23Q17/225 ,  Y10T29/49995 ,  Y10T29/49996 ,  Y10T29/5176 ,  Y10T408/5584 ,  Y10T409/400175 ,  Y10T409/402275 ,  Y10T409/405775 ,  Y10T409/40595 ,  Y10T409/406125 ,  Y10T409/4063 ,  Y10T409/4077

摘要： A device for centering a work piece with respect to a centerline of a tool includes a radially-stationary component rigidly secured with respect to the tool such that the radially-stationary component and the tool are concentric. A biasing mechanism is biased away from the radially-stationary component to apply substantially equally-distributed radial force at a periphery of the work piece to thereby center the work piece with respect to the tool. A method of broaching a work piece having an inner and an outer diameter includes machining the outer diameter and then applying circumferentially-distributed radial force to the inner diameter or the outer diameter to thereby center the work piece with respect to a broach tool. After the applying step, the method includes broaching the inner diameter of the work piece using the broach tool.

摘要翻译： 用于使工件相对于工具的中心线定心的装置包括相对于工具刚性地固定的径向固定部件，使得径向静止部件和工具是同心的。 偏置机构被偏压远离径向静止部件，以在工件的周边施加基本相等分布的径向力，从而使工件相对于工具居中。 拉削具有内径和外径的工件的方法包括加工外径，然后对内径或外径施加周向分布的径向力，从而使工件相对于拉刀工具居中。 在施加步骤之后，该方法包括使用拉刀工具拉削工件的内径。

公开(公告)号：US07295569B1

公开(公告)日：2007-11-13

申请号：US10383381

申请日：2003-03-07

申请人： Brian A. Arnold ,  Kaartik Viswanath ,  Jeffrey Lee ,  Pritesh N. Patel ,  Bruce B. Weller ,  Floyd H. Gerhardt ,  Snigdhendu S. Mukhopadhyay

发明人： Brian A. Arnold ,  Kaartik Viswanath ,  Jeffrey Lee ,  Pritesh N. Patel ,  Bruce B. Weller ,  Floyd H. Gerhardt ,  Snigdhendu S. Mukhopadhyay

IPC分类号： H04J3/16

CPC分类号： H04L67/303 ,  H04M3/007

摘要： Selecting a profile for an interface of a network device includes accessing profile sequences, where each profile sequence corresponds to an interface. Each profile sequence includes profiles that provide parameters for communicating data. The following are repeated for a profile sequence for an interface until a link satisfies a sequence criterion or until a last profile of the profile sequence is reached to select a profile for the interface. A current profile is accessed, and a link for the interface is initiated according to the current profile. Whether the link for the interface satisfies the sequence criterion in accordance with the margin set is determined. A next profile of the profile sequence is accessed if the link does not satisfy the sequence criterion in accordance with the margin set, and the current profile is selected if the link satisfies the sequence criterion. Data is communicated according to the selected profile.

摘要翻译： 选择网络设备的接口的配置文件包括访问配置文件序列，其中每个配置文件序列对应于接口。 每个配置文件序列包括提供用于传送数据的参数的配置文件。 对于接口的配置文件序列重复以下操作，直到链路满足序列标准或直到达到配置文件序列的最后一个配置文件以选择接口的配置文件为止。 访问当前配置文件，并根据当前配置文件启动该接口的链路。 确定接口的链路是否满足符合边距集的序列标准。 如果链路不符合符合边距集合的序列标准，则访问轮廓序列的下一轮廓，并且如果链路满足序列标准，则选择当前轮廓。 数据根据所选配置文件进行通信。

公开(公告)号：US20060097108A1

公开(公告)日：2006-05-11

申请号：US10965441

申请日：2004-10-13

申请人： Ketao Liu ,  Yeong-Wei Wu ,  Jeffrey Lee

发明人： Ketao Liu ,  Yeong-Wei Wu ,  Jeffrey Lee

IPC分类号： B64C17/06

CPC分类号： G01D5/208 ,  G01D3/02

摘要： In accordance with an embodiment of the present invention, a resolver system has at least one resolver and at least one amplifier in electrical communication with each resolver. A reference circuit is in electrical communication with the amplifiers. The reference circuit provides reference signals to the amplifiers. A non-linearity calibration and compensation circuit in communication with each amplifier uses the amplified reference signals to provide scale factors, so as to enhance a precision of the resolver system.

公开(公告)号：US06476799B1

公开(公告)日：2002-11-05

申请号：US09439222

申请日：1999-11-12

申请人： Jeffrey Lee ,  Po-Hsun Hsien ,  Kenny Chien

发明人： Jeffrey Lee ,  Po-Hsun Hsien ,  Kenny Chien

IPC分类号： G09G500

CPC分类号： G06F3/046

摘要： An apparatus is provided for the wireless capture of coordinate-shift information. The apparatus includes a pulse generator that generates a pulse signal and simultaneously distributes the pulse signal into a first signal along the first path and a second signal along the second path. The apparatus further includes a working area defined by a plurality of crossing X-axis signal lines and Y-axis signal lines, and at least one coil surrounding the working area for generating a magnetic field. The apparatus also includes a scanning circuit coupled to the working area, and a synchronic determination circuit coupled to the pulse generator and the scanning circuit for receiving the first and second signals, and for determining the time delay between the receipt of the first and second signals. The apparatus further includes a signal processing circuit coupled to the scanning circuit and the synchronic determination circuit. The first signal passes through the working area and the scanning circuit to the synchronic determination circuit, and contains coordinate shift information. The position indicator can include a resonance circuit that receives signals from the magnetic field, and then re-transmits resonance signals having different pulse widths to the working area.

摘要翻译： 提供了一种用于无线捕获坐标移位信息的装置。 该装置包括脉冲发生器，其产生脉冲信号并同时将脉冲信号沿第一路径分配成第一信号，沿着第二路径分配第二信号。 该装置还包括由多个交叉的X轴信号线和Y轴信号线限定的工作区域和围绕工作区域的至少一个线圈，用于产生磁场。 该装置还包括耦合到工作区域的扫描电路，以及耦合到脉冲发生器和扫描电路的同步确定电路，用于接收第一和第二信号，并确定接收第一和第二信号之间的时间延迟 。 该装置还包括耦合到扫描电路和同步确定电路的信号处理电路。 第一信号通过工作区域和扫描电路到同步确定电路，并包含坐标移位信息。 位置指示器可以包括从磁场接收信号的谐振电路，然后将具有不同脉冲宽度的谐振信号重新发送到工作区域。

公开(公告)号：US20120218747A1

公开(公告)日：2012-08-30

申请号：US13035705

申请日：2011-02-25

申请人： Jeffrey Lee

发明人： Jeffrey Lee

IPC分类号： F21V9/00

CPC分类号： F21V9/00 ,  G02B27/46 ,  Y10S362/80

摘要： One embodiment of the invention is directed to a light mixing illuminator for illuminating an object, comprising an array of light emitting elements wherein at least some of the elements emit light of different wavelengths. An optical device is employed that focuses the light from the elements to a Fourier plane of the device, wherein the light emitting elements are arranged so that at least the zero spatial frequency components of light of the different wavelengths from the elements substantially overlap in a region at the Fourier plane. An objective is used to project the region onto the object. A mask is used that selectively blocks some of spatial frequency components of light from the elements without blocking the zero spatial frequency components of light from reaching the object.

摘要翻译： 本发明的一个实施例涉及一种用于照亮物体的光混合照明器，包括一组发光元件，其中至少一些元件发射不同波长的光。 使用将来自元件的光聚焦到装置的傅立叶平面的光学装置，其中发光元件被布置成使得至少来自元件的不同波长的光的零空间频率分量在区域中基本上重叠 在傅里叶平面。 一个目标用于将该区域投影到对象上。 使用掩模，其选择性地阻挡来自元件的光的一些空间频率分量，而不阻挡光的零空间频率分量到达对象。