METHODS AND APPARATUS FOR RENAL NEUROMODULATION VIA STEREOTACTIC RADIOTHERAPY
    10.
    发明申请
    METHODS AND APPARATUS FOR RENAL NEUROMODULATION VIA STEREOTACTIC RADIOTHERAPY 审中-公开
    通过立体放射治疗进行肾神经调节的方法和装置

    公开(公告)号:US20110200171A1

    公开(公告)日:2011-08-18

    申请号:US13009748

    申请日:2011-01-19

    IPC分类号: A61N5/10

    摘要: The present disclosure describes methods and apparatus for renal neuromodulation via stereotactic radiotherapy for the treatment of hypertension, heart failure, chronic kidney disease, diabetes, insulin resistance, metabolic disorder or other ailments. Renal neuromodulation may be achieved by locating renal nerves and then utilizing stereotactic radiotherapy to expose the renal nerves to a radiation dose sufficient to reduce neural activity. A neural location element may be provided for locating target renal nerves, and a stereotactic radiotherapy system may be provided for exposing the located renal nerves to a radiation dose sufficient to reduce the neural activity, with reduced or minimized radiation exposure in adjacent tissue. Renal nerves may be located and targeted at the level of the ganglion and/or at postganglionic positions, as well as at pre-ganglionic positions.

    摘要翻译: 本公开描述了通过立体定向放射治疗高血压,心力衰竭,慢性肾脏疾病,糖尿病,胰岛素抵抗,代谢紊乱或其它疾病的肾神经调节的方法和装置。 肾神经调节可以通过定位肾神经,然后利用立体定向放射治疗来将肾神经暴露于足以减少神经活动的辐射剂量来实现。 可以提供用于定位目标肾神经的神经定位元件,并且可以提供立体定向放射治疗系统,用于将位于所述肾神经的辐射剂量暴露于足以减少或最小化相邻组织中的辐射暴露的神经活动的辐射剂量。 肾神经可能位于神经节水平和/或神经节后位置以及神经节前位置。