公开(公告)号：US20050148841A1

公开(公告)日：2005-07-07

申请号：US10736023

申请日：2003-12-15

申请人： Srijit Kamath ,  Sartaj Sahni ,  Jatinder Palta ,  Sanjay Ranka ,  Jonathan Li

发明人： Srijit Kamath ,  Sartaj Sahni ,  Jatinder Palta ,  Sanjay Ranka ,  Jonathan Li

IPC分类号： A61B5/05 ,  A61N5/10

CPC分类号： A61N5/103 ,  A61N5/1036 ,  A61N5/1042

摘要： A method of delivering radiation treatment using multi-leaf collimation includes the step of providing a radiation fluence map which includes an intensity profile. The fluence map is converted into a preliminary leaf sequence, wherein the preliminary leaf sequence minimizes machine on-time and is generated without leaf movement constraints. The leaf movement constraint is imposed on the preliminary leaf sequence. At least one constraint elimination algorithm is then applied, the algorithm adjusting the preliminary leaf sequence to minimize violations of the constraint while providing the desired fluence map and minimized radiation on-time. The method can be applied to SMLC and DLMC systems, and can include adjustment for the tongue-and-groove effect.

摘要翻译： 使用多叶准直进行放射治疗的方法包括提供包括强度分布的辐射注量图的步骤。 注量图被转换成初步的叶子序列，其中初步叶子序列使机器准时最小化，并且不产生叶片运动限制。 叶片运动约束对初步叶序列施加。 然后应用至少一个约束消除算法，该算法调整初步叶序列以最小化对约束的违反，同时提供期望的通量图和最小化的辐射on-time。 该方法可以应用于SMLC和DLMC系统，并且可以包括对榫槽效应的调整。

公开(公告)号：US20050254623A1

公开(公告)日：2005-11-17

申请号：US11102083

申请日：2005-04-08

申请人： Srijit Kamath ,  Sartaj Sahni ,  Jonathan Li ,  Jatinder Palta ,  Sanjay Ranka

发明人： Srijit Kamath ,  Sartaj Sahni ,  Jonathan Li ,  Jatinder Palta ,  Sanjay Ranka

IPC分类号： A61N5/10

CPC分类号： A61N5/1042 ,  A61N5/1036

摘要： A method of delivering intensity modulated radiation therapy (IMRT) is disclosed. An intensity profile for the treatment of a patient is provided which spans a prescribed field width and includes a discrete profile having intensity values at each of a plurality of sample points bounded by the prescribed width. The prescribed width is compared to a maximum field width provided by the radiation treatment system. The intensity profile is split into a plurality of intensity profile portions, each having respective widths less than the maximum width if the prescribed width is greater than the maximum width. The prescribed field is also divided into a plurality of different profile portion split arrangements. A monitor unit (MU) efficiency is calculated for each of the arrangements. One of the arrangements is selected for delivery by the system using a leaf sequencing method.

摘要翻译： 公开了一种递送强度调制放射治疗（IMRT）的方法。 提供了用于治疗患者的强度分布，其跨越规定的场宽度并且包括在由规定宽度限定的多个采样点中的每一个处具有强度值的离散轮廓。 将规定的宽度与辐射处理系统提供的最大场宽进行比较。 如果规定的宽度大于最大宽度，则强度分布被分成多个强度分布部分，每个强度分布部分各自具有小于最大宽度的宽度。 规定的场也被分成多个不同的轮廓部分割装置。 针对每个布置计算监视器单元（MU）的效率。 选择其中一种安排用于通过系统使用叶片测序方法递送。

公开(公告)号：US07142635B2

公开(公告)日：2006-11-28

申请号：US11102083

申请日：2005-04-08

申请人： Srijit Kamath ,  Sartaj Sahni ,  Jonathan Gang Li ,  Jatinder Palta ,  Sanjay Ranka

发明人： Srijit Kamath ,  Sartaj Sahni ,  Jonathan Gang Li ,  Jatinder Palta ,  Sanjay Ranka

IPC分类号： A61N5/10

CPC分类号： A61N5/1042 ,  A61N5/1036

摘要： A method of delivering intensity modulated radiation therapy (IMRT) is disclosed. An intensity profile for the treatment of a patient is provided which spans a prescribed field width and includes a discrete profile having intensity values at each of a plurality of sample points bounded by the prescribed width. The prescribed width is compared to a maximum field width provided by the radiation treatment system. The intensity profile is split into a plurality of intensity profile portions, each having respective widths less than the maximum width if the prescribed width is greater than the maximum width. The prescribed field is also divided into a plurality of different profile portion split arrangements. A monitor unit (MU) efficiency is calculated for each of the arrangements. One of the arrangements is selected for delivery by the system using a leaf sequencing method.

摘要翻译： 公开了一种递送强度调制放射治疗（IMRT）的方法。 提供了用于治疗患者的强度分布，其跨越规定的场宽度并且包括在由规定宽度限定的多个采样点中的每一个处具有强度值的离散轮廓。 将规定的宽度与辐射处理系统提供的最大场宽进行比较。 如果规定的宽度大于最大宽度，则强度分布被分成多个强度分布部分，每个强度分布部分各自具有小于最大宽度的宽度。 规定的场也被分成多个不同的轮廓部分割装置。 针对每个布置计算监视器单元（MU）的效率。 选择其中一种安排用于通过系统使用叶片测序方法递送。

公开(公告)号：US07573978B2

公开(公告)日：2009-08-11

申请号：US11995303

申请日：2006-07-11

申请人： Srijit Kamath ,  Sartaj Kumar Sahni ,  Jonathan Li ,  Jatinder Palta ,  Sanjay Ranka

发明人： Srijit Kamath ,  Sartaj Kumar Sahni ,  Jonathan Li ,  Jatinder Palta ,  Sanjay Ranka

IPC分类号： A61N5/10

CPC分类号： A61N5/1042 ,  A61N5/1036 ,  G21K1/04

摘要： A method and associated system 300 for delivering intensity-modulated radiation therapy (IMRT) uses variable feathering field splitting for intensity modulated fields of large size. A processor controls a beam-shaping device that splits the radiation beam into a plurality of radiation fields delivered to a patient. The processor in cooperation with the beam-shaping device implements a variable feathering method which includes providing an intensity matrix for the treatment of a patient, the intensity matrix having a plurality of rows and columns for spanning a prescribed radiation field including a prescribed field width. The prescribed width is compared to a maximum field width provided by the radiation treatment system. The intensity matrix is split into a plurality of spatially overlapping intensity submatrices by variably feathering the intensity matrix when the prescribed width exceeds the maximum field width, Radiotherapy is then provided to the patient using a leaf sequencing method to generate the submatrices.

摘要翻译： 用于递送强度调制辐射治疗（IMRT）的方法和相关系统300使用大尺寸强度调制场的可变羽化场分割。 处理器控制将辐射束分成传递给患者的多个辐射场的光束整形装置。 与光束成形装置协作的处理器实现了一种可变羽化方法，其包括提供用于治疗患者的强度矩阵，所述强度矩阵具有多个行和列，用于跨越包括规定场宽的规定辐射场。 将规定的宽度与辐射处理系统提供的最大场宽进行比较。 当规定的宽度超过最大场宽度时，强度矩阵通过可变地羽化强度矩阵而被分割成多个空间上重叠的强度子矩阵，然后使用叶子排序方法向患者提供放射疗法以产生子矩阵。

公开(公告)号：US20080240348A1

公开(公告)日：2008-10-02

申请号：US11995303

申请日：2006-07-11

申请人： Srijit Kamath ,  Sartaj Kumar Sahni ,  Jonathan Li ,  Jatinder Palta ,  Sanjay Ranka

发明人： Srijit Kamath ,  Sartaj Kumar Sahni ,  Jonathan Li ,  Jatinder Palta ,  Sanjay Ranka

IPC分类号： A61N5/10

CPC分类号： A61N5/1042 ,  A61N5/1036 ,  G21K1/04

摘要： A method and associated system 300 for delivering intensity-modulated radiation therapy (IMRT) uses variable feathering field splitting for intensity modulated fields of large size. Processor 112 controls a beam-shaping device 106 so that the beam-shaping device splits the radiation beam into a plurality of radiation fields delivered to the patient 102. Processor 112 in cooperation with beam-shaping device 106 implements a variable feathering method which includes the steps of providing an intensity matrix for the treatment of a patient, the intensity matrix having a plurality of rows and columns for spanning a prescribed radiation field including a prescribed field width. The prescribed width is compared to a maximum field width provided by the radiation treatment system. The intensity matrix is split into a plurality of spatially overlapping intensity submatrices when the prescribed width exceeds the maximum field width, wherein the splitting comprises variably feathering the intensity matrix. Radiotherapy is then provided to the patient 102 using a leaf sequencing method to generate the submatrices.

摘要翻译： 用于递送强度调制辐射治疗（IMRT）的方法和相关系统300使用大尺寸强度调制场的可变羽化场分割。 处理器112控制光束整形装置106，使得光束整形装置将辐射束分成传送到患者102的多个辐射场。 与光束整形装置106协作的处理器112实现可变羽化方法，其包括提供用于治疗患者的强度矩阵的步骤，所述强度矩阵具有多个行和列，用于跨越规定的辐射场，包括规定的 字段宽度。 将规定的宽度与辐射处理系统提供的最大场宽进行比较。 当规定的宽度超过最大场宽时，强度矩阵被分割成多个空间上重叠的强度子矩阵，其中分割包括可变地羽化强度矩阵。 然后使用叶片测序方法向患者102提供放射疗法以产生子矩阵。

公开(公告)号：US07085348B2

公开(公告)日：2006-08-01

申请号：US10736023

申请日：2003-12-15

申请人： Srijit Kamath ,  Sartaj Sahni ,  Jantinder Palta ,  Sanjay Ranka ,  Jonathan G. Li

发明人： Srijit Kamath ,  Sartaj Sahni ,  Jantinder Palta ,  Sanjay Ranka ,  Jonathan G. Li

IPC分类号： A61N5/10

CPC分类号： A61N5/103 ,  A61N5/1036 ,  A61N5/1042

摘要： A method of delivering radiation treatment using multi-leaf collimation includes the step of providing a radiation fluence map which includes an intensity profile. The fluence map is converted into a preliminary leaf sequence, wherein the preliminary leaf sequence minimizes machine on-time and is generated without leaf movement constraints. The leaf movement constraint is imposed on the preliminary leaf sequence. At least one constraint elimination algorithm is then applied, the algorithm adjusting the preliminary leaf sequence to minimize violations of the constraint while providing the desired fluence map and minimized radiation on-time. The method can be applied to SMLC and DLMC systems, and can include adjustment for the tongue-and-groove effect.

摘要翻译： 使用多叶准直进行放射治疗的方法包括提供包括强度分布的辐射注量图的步骤。 注量图被转换成初步的叶子序列，其中初步叶子序列使机器准时最小化，并且不产生叶片运动限制。 叶片运动约束对初步叶序列施加。 然后应用至少一个约束消除算法，该算法调整初步叶序列以最小化对约束的违反，同时提供期望的通量图和最小化的辐射on-time。 该方法可以应用于SMLC和DLMC系统，并且可以包括对榫槽效应的调整。

公开(公告)号：US08144686B2

公开(公告)日：2012-03-27

申请号：US11738464

申请日：2007-04-20

申请人： Sartaj Sahni ,  Nageswara Sirikonda Venkata Rao ,  Sanjay Ranka ,  Yan Li ,  Eun-Sung Jung ,  Narayana Kamath

发明人： Sartaj Sahni ,  Nageswara Sirikonda Venkata Rao ,  Sanjay Ranka ,  Yan Li ,  Eun-Sung Jung ,  Narayana Kamath

IPC分类号： H04L12/28

CPC分类号： H04L41/0896 ,  H04L47/70 ,  H04L47/724 ,  H04L47/781 ,  H04L47/805 ,  H04L47/826

摘要： A connection-oriented network includes a control server. The control server receives requests to establish and utilize dedicated channels in the network. The control server utilizes various scheduling methods and algorithms to determine channels based on the request's requirements and resources of the network. For example, the control server may determine a channel based on: (i) a specified bandwidth in a specified time slot, (ii) highest available bandwidth in a specified time slot, (iii) earliest available time with a specified bandwidth and duration, and (iv) all available time slots with a specified bandwidth and duration.

摘要翻译： 面向连接的网络包括控制服务器。 控制服务器接收到建立和利用网络中的专用信道的请求。 控制服务器利用各种调度方法和算法，根据请求的要求和网络的资源来确定信道。 例如，控制服务器可以基于以下方式确定信道：（i）指定时隙中的指定带宽，（ii）指定时隙中的最高可用带宽，（iii）具有指定带宽和持续时间的最早可用时间， 和（iv）具有指定带宽和持续时间的所有可用时隙。

公开(公告)号：US20080259954A1

公开(公告)日：2008-10-23

申请号：US11738464

申请日：2007-04-20

申请人： Sartaj Sahni ,  Nageswara Sirikonda Venkata Rao ,  Sanjay Ranka ,  Yan Li ,  Eun-Sung Jung ,  Narayana Kamath

发明人： Sartaj Sahni ,  Nageswara Sirikonda Venkata Rao ,  Sanjay Ranka ,  Yan Li ,  Eun-Sung Jung ,  Narayana Kamath

IPC分类号： H04J3/16 ,  H04J3/22

CPC分类号： H04L41/0896 ,  H04L47/70 ,  H04L47/724 ,  H04L47/781 ,  H04L47/805 ,  H04L47/826

摘要： A connection-oriented network includes a control server. The control server receives requests to establish and utilize dedicated channels in the network. The control server utilizes various scheduling methods and algorithms to determine channels based on the request's requirements and resources of the network. For example, the control server may determine a channel based on: (i) a specified bandwidth in a specified time slot, (ii) highest available bandwidth in a specified time slot, (iii) earliest available time with a specified bandwidth and duration, and (iv) all available time slots with a specified bandwidth and duration.

摘要翻译： 面向连接的网络包括控制服务器。 控制服务器接收到建立和利用网络中的专用信道的请求。 控制服务器利用各种调度方法和算法，根据请求的要求和网络的资源来确定信道。 例如，控制服务器可以基于以下方式确定信道：（i）指定时隙中的指定带宽，（ii）指定时隙中的最高可用带宽，（iii）具有指定带宽和持续时间的最早可用时间， 和（iv）具有指定带宽和持续时间的所有可用时隙。

公开(公告)号：US08086485B1

公开(公告)日：2011-12-27

申请号：US12541528

申请日：2009-08-14

申请人： Sanjay Ranka ,  Jason S. Lenderman ,  James R. Weisinger

发明人： Sanjay Ranka ,  Jason S. Lenderman ,  James R. Weisinger

IPC分类号： G06F17/30

CPC分类号： G06Q30/02 ,  G06Q10/06315 ,  G06Q10/0639 ,  G06Q30/0201 ,  G06Q30/0204 ,  G06Q30/0205 ,  G06Q30/0241 ,  G06Q30/0242 ,  G06Q30/0244 ,  G06Q30/0256 ,  G06Q30/0277 ,  G06Q30/0631 ,  G06Q30/0633

摘要： Method, procedure, algorithm, system, and computer program for improving and attempting to optimize the performance of messaging campaigns, particularly to marketing campaigns in which advertisements or other messages are distributed over an interactive measurable medium such as the Internet. A goal is to allocate the message alternatives to the customer population to optimize business objectives. The includes reading prior stage message state data pertaining to a prior stage including a cumulative number of trials and a cumulative number of successes for a particular message. Message performance results representing message trials and message successes from the previous stage based on the prior-stage state are then read, and a current message state is computed. A current message allocation is generated based on the current message state. Desirably the cumulative number of trials and the cumulative number of successes are discounted based on the age of the information. This inventive procedure may be applied to various message types including, for example, web site banner advertisements, electronic advertisements generally, email messages and promotions, and the like. In one embodiment, the messages are internet web site banner ads, trials are impressions of the ads presented to the user, and successes are measured by clickthroughs from the banner ad to the web site associated with the banner ad. Computer system, computer program, and computer program product associated with the inventive method and procedures are also provided.

摘要翻译： 方法，程序，算法，系统和计算机程序，用于改进和尝试优化消息传播活动的性能，特别是在诸如因特网的交互式可测量介质上分发广告或其他消息的营销活动。 目标是为客户群体分配消息替代品，以优化业务目标。 这包括读取与前一阶段相关的前级消息状态数据，其包括累积的试验次数和针对特定消息的累积成功次数。 然后读取表示基于前一级状态的前一级的消息试验和消息成功的消息性能结果，并且计算当前消息状态。 基于当前消息状态生成当前消息分配。 理想的是，根据信息的年龄，累积的试验次数和累积的成功次数将被打折扣。 本发明的过程可以应用于各种消息类型，包括例如网站横幅广告，通常的电子广告，电子邮件消息和促销等。 在一个实施例中，消息是互联网网站横幅广告，试验是向用户呈现的广告的印象，成功通过从横幅广告到与横幅广告相关联的网站的点击来衡量。 还提供了与本发明的方法和程序相关联的计算机系统，计算机程序和计算机程序产品。

公开(公告)号：US20070050204A1

公开(公告)日：2007-03-01

申请号：US11589408

申请日：2006-10-30

申请人： Sanjay Ranka ,  Jason Lenderman ,  James Weisinger

发明人： Sanjay Ranka ,  Jason Lenderman ,  James Weisinger

IPC分类号： G06Q99/00

CPC分类号： G06Q30/02 ,  G06Q10/06315 ,  G06Q10/0639 ,  G06Q30/0201 ,  G06Q30/0204 ,  G06Q30/0205 ,  G06Q30/0241 ,  G06Q30/0242 ,  G06Q30/0244 ,  G06Q30/0256 ,  G06Q30/0277 ,  G06Q30/0631 ,  G06Q30/0633

摘要： Method, procedure, algorithm, system, and computer program for improving and attempting to optimize the performance of messaging campaigns, particularly to marketing campaigns in which advertisements or other messages are distributed over an interactive measurable medium such as the Internet. A goal is to allocate the message alternatives to the customer population to optimize business objectives. The includes reading prior stage message state data pertaining to a prior stage including a cumulative number of trials and a cumulative number of successes for a particular message. Message performance results representing message trials and message successes from the previous stage based on the prior-stage state are then read, and a current message state is computed. A current message allocation is generated based on the current message state. Desirably the cumulative number of trials and the cumulative number of successes are discounted based on the age of the information. This inventive procedure may be applied to various message types including, for example, web site banner advertisements, electronic advertisements generally, email messages and promotions, and the like. In one embodiment, the messages are internet web site banner ads, trials are impressions of the ads presented to the user, and successes are measured by clickthroughs from the banner ad to the web site associated with the banner ad. Computer system, computer program, and computer program product associated with the inventive method and procedures are also provided by the invention.

摘要翻译： 方法，程序，算法，系统和计算机程序，用于改进和尝试优化消息传播活动的性能，特别是在诸如因特网的交互式可测量介质上分发广告或其他消息的营销活动。 目标是为客户群体分配消息替代品，以优化业务目标。 这包括读取与前一阶段相关的前级消息状态数据，其包括累积的试验次数和针对特定消息的累积成功次数。 然后读取表示基于前一级状态的前一级的消息试验和消息成功的消息性能结果，并且计算当前消息状态。 基于当前消息状态生成当前消息分配。 理想的是，根据信息的年龄，累积的试验次数和累积的成功次数将被打折扣。 本发明的过程可以应用于各种消息类型，包括例如网站横幅广告，通常的电子广告，电子邮件消息和促销等。 在一个实施例中，消息是互联网网站横幅广告，试验是向用户呈现的广告的印象，成功通过从横幅广告到与横幅广告相关联的网站的点击来衡量。 本发明还提供了与本发明方法和程序相关联的计算机系统，计算机程序和计算机程序产品。