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公开(公告)号：US20210130402A1
公开(公告)日：2021-05-06
申请号：US16903566
申请日：2020-06-17
发明人： Liping Liu , Lawrence Gu
IPC分类号： C07K5/11 , C07K5/065 , C07K5/068 , C07K5/087 , C07K5/09 , C07K5/107 , G01N33/50 , G01N33/68 , C07K5/072 , G01N30/02 , H01J49/00 , C07K5/06
摘要： The disclosure provides compositions and methods relating to aromatic-cationic peptides. The methods comprise administering to the subject an effective amount of an aromatic-cationic peptide to subjects in need thereof. For example, the peptides may be administered to subjects in need of a mitochondrial-targeted antioxidant.
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2.发明授权公开(公告)号：US09549963B2
公开(公告)日：2017-01-24
申请号：US14671538
申请日：2015-03-27
发明人： Liping Liu , Shibo Tang , Xiaoling Liang
CPC分类号： A61K38/06 , A61K38/07 , A61K45/06 , A61P27/02 , A61P27/12 , C07K5/0817 , C07K5/1016
摘要： The disclosure generally describes methods of preventing or treating ophthalmic diseases or conditions in a mammalian subject, such as diabetic retinopathy, cataracts, retinitis pigmentosa, glaucoma, macular degeneration, choroidal neovascularization, retinal degeneration, and oxygen-induced retinopathy. The methods comprise administering an effective amount of an aromatic-cationic peptide to subjects in need thereof.
摘要翻译： 本发明总体上描述了预防或治疗哺乳动物受试者的眼科疾病或病症的方法，例如糖尿病性视网膜病变，白内障，色素性视网膜炎，青光眼，黄斑变性，脉络膜新生血管形成，视网膜变性和氧诱导的视网膜病变。 所述方法包括向有需要的受试者施用有效量的芳族阳离子肽。
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公开(公告)号：US20160376309A1
公开(公告)日：2016-12-29
申请号：US15012286
申请日：2016-02-01
发明人： Liping Liu , Lawrence Gu
CPC分类号： C07K5/1019 , A61K38/00 , C07K5/06008 , C07K5/06078 , C07K5/06086 , C07K5/06095 , C07K5/0812 , C07K5/0815 , C07K5/0817 , C07K5/1016 , G01N30/02 , G01N33/5076 , G01N33/5079 , G01N33/6812 , G01N2030/027 , H01J49/0027
摘要： The disclosure provides compositions and methods relating to aromatic-cationic peptides. The methods comprise administering to the subject an effective amount of an aromatic-cationic peptide to subjects in need thereof. For example, the peptides may be administered to subjects in need of a mitochondrial-targeted antioxidant.
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公开(公告)号：US20190106458A1
公开(公告)日：2019-04-11
申请号：US15978259
申请日：2018-05-14
发明人： Liping Liu , Lawrence Gu
IPC分类号： C07K5/11 , G01N33/50 , C07K5/06 , C07K5/09 , H01J49/00 , C07K5/072 , G01N30/02 , G01N33/68 , C07K5/107 , C07K5/087 , C07K5/068 , C07K5/065
摘要： The disclosure provides compositions and methods relating to aromatic-cationic peptides. The methods comprise administering to the subject an effective amount of an aromatic-cationic peptide to subjects in need thereof For example, the peptides may be administered to subjects in need of a mitochondrial-targeted antioxidant.
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公开(公告)号：US20210154259A1
公开(公告)日：2021-05-27
申请号：US16919777
申请日：2020-07-02
发明人： Liping Liu , Shibo Tang , Xiaoling Liang
摘要： The disclosure generally describes methods of preventing or treating ophthalmic diseases or conditions in a mammalian subject, such as diabetic retinopathy, cataracts, retinitis pigmentosa, glaucoma, macular degeneration, choroidal neovascularization, retinal degeneration, and oxygen-induced retinopathy. The methods comprise administering an effective amount of an aromatic-cationic peptide to subjects in need thereof.
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公开(公告)号：US10188692B2
公开(公告)日：2019-01-29
申请号：US15401527
申请日：2017-01-09
发明人： Liping Liu , Shibo Tang , Xiaoling Liang
摘要： The disclosure generally describes methods of preventing or treating ophthalmic diseases or conditions in a mammalian subject, such as diabetic retinopathy, cataracts, retinitis pigmentosa, glaucoma, macular degeneration, choroidal neovascularization, retinal degeneration, and oxygen-induced retinopathy. The methods comprise administering an effective amount of an aromatic-cationic peptide to subjects in need thereof.
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