公开(公告)号：US5725836A

公开(公告)日：1998-03-10

申请号：US457522

申请日：1995-06-01

申请人： Stephane Fabrice Rouanet ,  William Edward McGovern ,  Wanging Cao ,  John M. Moses ,  Angel L. Carrillo ,  Irving M. Klotz

发明人： Stephane Fabrice Rouanet ,  William Edward McGovern ,  Wanging Cao ,  John M. Moses ,  Angel L. Carrillo ,  Irving M. Klotz

IPC分类号： A61K8/00 ,  A61K8/02 ,  A61K8/20 ,  A61K8/23 ,  A61K8/26 ,  A61K8/27 ,  A61K8/28 ,  A61K8/33 ,  A61K8/36 ,  A61K8/49 ,  A61Q15/00 ,  B01D9/00 ,  B01J2/00 ,  B01J13/00 ,  C01F7/00 ,  C01F7/48 ,  C01F7/56 ,  C01G25/00 ,  A61K7/34 ,  A61K7/56

CPC分类号： A61Q15/00 ,  A61K8/042 ,  A61K8/26 ,  B01J13/0091

摘要： A method for providing aerogels, and aerogels produced according to the method, is described. As one aspect, antiperspirant compounds that are in aerogel form, and antiperspirant and deodorant compositions including such salts, are described. The method involves contacting a solution containing material to be processed with a species selected to precipitate the material and selected so as to be miscible with the solvent system of the solution. After the material is precipitated, the material may be washed with the precipitating species until it is substantially free of solvent system. Then, the precipitating species containing the material precipitate is taken above its critical point, and the supercritical fluid is exhausted above its critical temperature. Alternately, a separate isolating species is introduced to displace the precipitating species, or the precipitating species/solvent system mixture. The isolating species then is taken above its critical point, and exhausted above its critical temperature. The invention provides for batch or continuous processes.

摘要翻译： 描述了一种提供气凝胶和根据该方法生产的气凝胶的方法。 一方面，描述了气凝胶形式的止汗化合物，以及包含这些盐的止汗剂和除臭剂组合物。 该方法包括将待处理材料的溶液与选择的物质接触以沉淀材料并选择以便与溶液的溶剂体系混溶。 材料沉淀后，材料可以用沉淀物质洗涤，直到其基本上不含溶剂体系。 然后，将含有物质沉淀物的沉淀物质高于其临界点，超临界流体在其临界温度以上耗尽。 或者，引入单独的隔离物质以置换沉淀物质或沉淀物质/溶剂体系混合物。 然后将隔离物质置于其临界点以上，并在其临界温度以上耗尽。 本发明提供批量或连续方法。

公开(公告)号：US5864923A

公开(公告)日：1999-02-02

申请号：US920287

申请日：1997-08-26

申请人： Stephane Fabrice Rouanet ,  William Edward McGovern ,  Wanqing Cao ,  John M. Moses ,  Angel L. Carrillo ,  Irving M. Klotz

发明人： Stephane Fabrice Rouanet ,  William Edward McGovern ,  Wanqing Cao ,  John M. Moses ,  Angel L. Carrillo ,  Irving M. Klotz

IPC分类号： A61K8/00 ,  A61K8/02 ,  A61K8/20 ,  A61K8/23 ,  A61K8/26 ,  A61K8/27 ,  A61K8/28 ,  A61K8/33 ,  A61K8/36 ,  A61K8/49 ,  A61Q15/00 ,  B01D9/00 ,  B01J2/00 ,  B01J13/00 ,  C01F7/00 ,  C01F7/48 ,  C01F7/56 ,  C01G25/00 ,  B01D17/00 ,  C07C7/10

CPC分类号： A61Q15/00 ,  A61K8/042 ,  A61K8/26 ,  B01J13/0091

摘要： A method for providing aerogels, and aerogels produced according to the method, is described. As one aspect, antiperspirant compounds that are in aerogel form, and antiperspirant and deodorant compositions including such salts, are described. The method involves contacting a solution containing material to be processed with a species selected to precipitate the material and selected so as to be miscible with the solvent system of the solution. After the material is precipitated, the material may be washed with the precipitating species until it is substantially free of solvent system. Then, the precipitating species containing the material precipitate is taken above its critical point, and the supercritical fluid is exhausted above its critical temperature. Alternately, a separate isolating species is introduced to displace the precipitating species, or the precipitating species/solvent system mixture. The isolating species then is taken above its critical point, and exhausted above its critical temperature. The invention provides for batch or continuous processes.

摘要翻译： 描述了一种提供气凝胶和根据该方法生产的气凝胶的方法。 一方面，描述了气凝胶形式的止汗化合物，以及包含这些盐的止汗剂和除臭剂组合物。 该方法包括将待处理材料的溶液与选择的物质接触以沉淀材料并选择以便与溶液的溶剂体系混溶。 材料沉淀后，材料可以用沉淀物质洗涤，直到其基本上不含溶剂体系。 然后，将含有物质沉淀物的沉淀物质高于其临界点，超临界流体在其临界温度以上耗尽。 或者，引入单独的隔离物质以置换沉淀物质或沉淀物质/溶剂体系混合物。 然后将隔离物质置于其临界点以上，并在其临界温度以上耗尽。 本发明提供批量或连续方法。

公开(公告)号：US4719176A

公开(公告)日：1988-01-12

申请号：US547232

申请日：1983-10-31

申请人： Irving M. Klotz

发明人： Irving M. Klotz

IPC分类号： C12Q1/68 ,  G01N33/532 ,  G01N33/542 ,  G01N33/58 ,  G01N33/53 ,  G01N33/566

CPC分类号： C12Q1/68 ,  G01N33/532 ,  G01N33/542 ,  G01N33/58 ,  G01N33/581 ,  Y10S435/81 ,  Y10S436/808

摘要： An enzyme-free diagnostic reagent, methods of its use and diagnostic systems containing that reagent are disclosed. The enzyme-free diagnostic reagent comprises an enzyme-free catalyst coupled by a linking group to a first binding agent, binds in aqueous medium to a second binding moiety to form a binding complex, and indicates the amount of second binding moiety present in the complex by means of its catalytic reactivity with co-reactant molecules.

摘要翻译： 公开了一种无酶诊断试剂，其使用方法和含该试剂的诊断系统。 无酶诊断试剂包括通过连接基团与第一结合剂偶联的无酶催化剂，在水性介质中结合到第二结合部分以形成结合复合物，并且指示存在于复合物中的第二结合部分的量 通过其与共反应物分子的催化反应性。