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公开(公告)号:US07273605B2
公开(公告)日:2007-09-25
申请号:US10856118
申请日:2004-05-27
IPC分类号: A61K48/00 , A61K39/02 , A61K39/12 , A61K39/275 , A61K39/015 , A01N63/00 , C12N15/863 , C12N15/00 , C12N15/09
CPC分类号: C12N15/86 , A61K39/0011 , A61K39/015 , A61K39/04 , A61K39/12 , A61K39/275 , A61K2039/523 , A61K2039/5254 , A61K2039/5256 , A61K2039/53 , A61K2039/545 , A61K2039/57 , A61K2039/58 , A61K2039/585 , C12N7/00 , C12N2710/24043 , C12N2770/24143 , Y02A50/41 , Y02A50/412
摘要: The present invention relates to a fowlpox virus genome which has modifications in one or more wild-type FPV genes. The present invention also relates to a viral particle comprising such a genome and its use to deliver a nucleotide of interest (NOI) to a target cell. The present invention also relates to vaccination methods, particularly a method which comprises administering a priming composition (which comprises a first non-replicating viral vector) and a boosting composition (which comprises a second non-replicating viral vector) to a subject to treat and/or prevent a disease.
摘要翻译: 本发明涉及在一种或多种野生型FPV基因中具有修饰的禽痘病毒基因组。 本发明还涉及包含这种基因组的病毒颗粒及其将目标核苷酸(NOI)递送至靶细胞的用途。 本发明还涉及疫苗接种方法,特别是一种方法,其包括给受治疗者施用引发组合物(其包含第一非复制型病毒载体)和加强组合物(其包含第二非复制型病毒载体)和 /或预防疾病。
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公开(公告)号:US20050025747A1
公开(公告)日:2005-02-03
申请号:US10856118
申请日:2004-05-27
申请人: Stephen Laidlaw , Mike Skinner , Adrian Hill , Sarah Gilbert , Richard Anderson
发明人: Stephen Laidlaw , Mike Skinner , Adrian Hill , Sarah Gilbert , Richard Anderson
IPC分类号: C12N15/09 , A61K35/76 , A61K39/00 , A61K39/015 , A61K39/04 , A61K39/275 , A61K39/295 , A61P31/06 , A61P33/06 , C12N7/00 , C12N15/863 , A61K48/00
CPC分类号: C12N15/86 , A61K39/0011 , A61K39/015 , A61K39/04 , A61K39/12 , A61K39/275 , A61K2039/523 , A61K2039/5254 , A61K2039/5256 , A61K2039/53 , A61K2039/545 , A61K2039/57 , A61K2039/58 , A61K2039/585 , C12N7/00 , C12N2710/24043 , C12N2770/24143 , Y02A50/41 , Y02A50/412
摘要: The present invention relates to a fowlpox virus genome which has modifications in one or more wild-type FPV genes. The present invention also relates to a viral particle comprising such a genome and its use to deliver a nucleotide of interest (NOI) to a target cell. The present invention also relates to vaccination methods, particularly a method which comprises administering a priming composition (which comprises a first non-replicating viral vector) and a boosting composition (which comprises a second non-replicating viral vector) to a subject to treat and/or prevent a disease.
摘要翻译: 本发明涉及在一种或多种野生型FPV基因中具有修饰的禽痘病毒基因组。 本发明还涉及包含这种基因组的病毒颗粒及其将目标核苷酸(NOI)递送至靶细胞的用途。 本发明还涉及疫苗接种方法,特别是一种方法,其包括给受治疗者施用引发组合物(其包含第一非复制型病毒载体)和加强组合物(其包含第二非复制型病毒载体)和 /或预防疾病。
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