-
公开(公告)号：US5723969A
公开(公告)日：1998-03-03
申请号：US660259
申请日：1996-06-07
CPC分类号： H02J7/0093
摘要： A high voltage charger operates in a three-phase cycle. In a first phase, the high voltage charger operates at a fixed frequency. In a second phase, the high voltage charger operates at a variable frequency designed to draw a substantially constant average current from a power source. In the third phase, the high voltage charger returns to fixed frequency operation. The variable frequency is the reciprocal of the sum of an on-time and an off-time of the switch. In one embodiment, the on-time is provided by the time required for the switch to reach a predetermined maximum and the off-time is provided by the time over which a magnetic field in a transformer collapses.
摘要翻译： 高压充电器以三相循环工作。 在第一阶段，高压充电器以固定频率工作。 在第二阶段中，高压充电器以设计成从电源绘制基本恒定的平均电流的可变频率工作。 在第三阶段，高压充电器返回固定频率运行。 可变频率是开关的导通时间和关断时间之和的倒数。 在一个实施例中，导通时间由开关达到预定最大值所需的时间提供，并且关断时间由变压器中的磁场塌陷的时间提供。
-
公开(公告)号：US20100331717A1
公开(公告)日：2010-12-30
申请号：US12880138
申请日：2010-09-12
申请人： Benjamin D. Pless , Stephen T. Archer , Craig M. Baysinger , Barbara Gibb , Suresh Gurunathan , Bruce Kirkpatrick , Thomas K. Tcheng
发明人： Benjamin D. Pless , Stephen T. Archer , Craig M. Baysinger , Barbara Gibb , Suresh Gurunathan , Bruce Kirkpatrick , Thomas K. Tcheng
IPC分类号： A61B5/0476
CPC分类号： A61B5/4094 , A61B5/04012 , A61B5/0476 , A61B5/0478 , A61B5/6868 , A61B5/7203 , A61B5/7242 , A61B5/7246 , A61B5/7264 , A61B5/7275
摘要： A system and method for detecting and predicting neurological events with an implantable device uses a relatively low-power central processing unit in connection with signal processing circuitry to identify features (including half waves) and calculate window-based characteristics (including line lengths and areas under the curve of the waveform) in an electrographic signal received from a patient's brain. The features and window-based characteristics are combinable in various ways according to the invention to detect and predict neurological events in real time, enabling responsive action by the implantable device.
摘要翻译： 使用可植入装置检测和预测神经病学的系统和方法使用与信号处理电路相关联的相对低功率的中央处理单元来识别特征（包括半波）并计算基于窗口的特征（包括线路长度和面积 在从患者的大脑接收的电图信号中波形的曲线）。 根据本发明的特征和基于窗口的特征可以以各种方式组合以实时检测和预测神经病学事件，从而能够实现可植入装置的响应动作。
-
公开(公告)号：US07813793B2
公开(公告)日：2010-10-12
申请号：US10973091
申请日：2004-10-25
申请人： Benjamin D. Pless , Stephen T. Archer , Craig M. Baysinger , Barbara Gibb , Suresh Gurunathan , Bruce Kirkpatrick , Thomas K. Tcheng
发明人： Benjamin D. Pless , Stephen T. Archer , Craig M. Baysinger , Barbara Gibb , Suresh Gurunathan , Bruce Kirkpatrick , Thomas K. Tcheng
IPC分类号： A61B5/00
CPC分类号： A61B5/4094 , A61B5/04012 , A61B5/0476 , A61B5/0478 , A61B5/6868 , A61B5/7203 , A61B5/7242 , A61B5/7246 , A61B5/7264 , A61B5/7275 , G06F19/00
摘要： A system and method for detecting and predicting neurological events with an implantable device uses a relatively low-power central processing unit in connection with signal processing circuitry to identify features (including half waves) and calculate window-based characteristics (including line lengths and areas under the curve of the waveform) in an electrographic signal received from a patient's brain. The features and window-based characteristics are combinable in various ways according to the invention to detect and predict neurological events in real time, enabling responsive action by the implantable device.
摘要翻译： 使用可植入装置检测和预测神经病学的系统和方法使用与信号处理电路相关联的相对低功率的中央处理单元来识别特征（包括半波）并计算基于窗口的特征（包括线路长度和面积 在从患者的大脑接收的电图信号中波形的曲线）。 根据本发明的特征和基于窗口的特征可以以各种方式组合以实时检测和预测神经病学事件，从而能够实现可植入装置的响应作用。
-
公开(公告)号：US06810285B2
公开(公告)日：2004-10-26
申请号：US09896092
申请日：2001-06-28
申请人： Benjamin D. Pless , Stephen T. Archer , Craig M. Baysinger , Barbara Gibb , Suresh K. Gurunathan , Bruce Kirkpatrick , Thomas K. Tcheng
发明人： Benjamin D. Pless , Stephen T. Archer , Craig M. Baysinger , Barbara Gibb , Suresh K. Gurunathan , Bruce Kirkpatrick , Thomas K. Tcheng
IPC分类号： A61B50476
CPC分类号： A61B5/4094 , A61B5/04012 , A61B5/0476 , A61B5/0478 , A61B5/6868 , A61B5/7203 , A61B5/7242 , A61B5/7246 , A61B5/7264 , A61B5/7275 , G06F19/00
摘要： A system and method for detecting and predicting neurological events with an implantable device uses a relatively low-power central processing unit in connection with signal processing circuitry to identify features (including half waves) and calculate window-based characteristics (including line lengths and areas under the curve of the waveform) in an electrographic signal received from a patient's brain. The features and window-based characteristics are combinable in various ways according to the invention to detect and predict neurological events in real time, enabling responsive action by the implantable device.
摘要翻译： 使用可植入装置检测和预测神经病学的系统和方法使用与信号处理电路相关联的相对低功率的中央处理单元来识别特征（包括半波）并计算基于窗口的特征（包括线路长度和面积 在从患者的大脑接收的电图信号中波形的曲线）。 根据本发明的特征和基于窗口的特征可以以各种方式组合以实时检测和预测神经病学事件，从而能够实现可植入装置的响应作用。
-
公开(公告)号：US06690974B2
公开(公告)日：2004-02-10
申请号：US09952901
申请日：2001-09-11
IPC分类号： A61N100
CPC分类号： A61N1/36064
摘要： An implantable multimodal neurostimulator having improved efficacy in treating epilepsy and other neurological disorders and processes of using that neurostimulator are described herein. The neurostimulator itself generally has two modes of electrical stimulation. The first involves delivering a non-responsive electrical stimulation signal that is applied to the central nervous system to reduce the likelihood of a seizure or other undesirable neurological even from occurring. Various waveform morphologies are described for non-responsive stimulation signals. A second mode involves delivering a responsive electrical stimulation signal when epileptiform waveforms are impending or extant. The responsive electrical stimulation signal is intended to terminate epileptiform activity, e.g., to desynchronize abnormally synchronous brain electrical activity.
摘要翻译： 本文描述了具有改善的治疗癫痫和其它神经障碍的功效的植入式多模式神经刺激器和使用该神经刺激器的过程。 神经刺激器本身通常具有两种电刺激模式。 第一个涉及提供应用于中枢神经系统的无反应性电刺激信号，以减少甚至发生癫痫发作或其他不希望的神经系统的可能性。 描述了用于无响应刺激信号的各种波形形态。 第二模式涉及当癫痫样波形即将到来或现存时递送响应电刺激信号。 响应性电刺激信号旨在终止癫痫样活动，例如使异常同步的脑电活动失步。
-
公开(公告)号：US06354299B1
公开(公告)日：2002-03-12
申请号：US09609086
申请日：2000-06-30
IPC分类号： A61B1900
CPC分类号： A61N1/37217 , A61N1/36025 , A61N1/36082 , A61N1/36135
摘要： An implantable device incorporating an acoustic transducer allows information and alerts to be communicated from the device to a patient. Sounds, including but not limited to buzzes, tones, sequences of tones, combinations of tones, complex sounds, and segments of reproduced or simulated human speech, are transmitted from an intracranially implanted portion of the device via bone conduction to the patient's ears, particularly the inner ears. In the disclosed embodiment, the acoustic transducer is used in cooperation with an implantable closed-loop system for the treatment of certain neurological disorders such as epilepsy, migraine headaches and Parkinson's disease, to warn the patient of an imminent seizure or other episode, to provide information to the patient on the state of the implantable apparatus, and to provide reminders and other information to the patient.
摘要翻译： 结合声学换能器的可植入装置允许将信息和警报从装置传送到患者。 特别是通过骨传导从设备的颅内植入部分发送声音，包括但不限于嗡嗡声，音调，音调序列，音调的组合，复合声音和再现或模拟人类语言的段 内耳。 在所公开的实施例中，声换能器与用于治疗某些神经障碍如癫痫，偏头痛和帕金森病的可植入闭环系统配合使用，以警告患者即将发作或其他发作，以提供 向患者提供关于植入式装置的状态的信息，并向患者提供提醒和其他信息。
-
公开(公告)号：US5919214A
公开(公告)日：1999-07-06
申请号：US967872
申请日：1997-11-12
CPC分类号： A61N1/37211 , A61N1/37229 , Y10S128/903
摘要： A method for ensuring two-sided telemetry in implantable cardiac therapy devices by making at least one of the following operating parameters selectable (reversible): (1) the direction of current detection of the telemetry circuitry of the implantable cardiac therapy device; (2) the direction of the magnetic field produced by the transmit coil of an external telemetry device (programming wand); (3) the direction of the magnetic field produced by the T/R coil of the implantable cardiac therapy device; and/or (4) the direction of current detection of the telemetry circuitry of the programming wand. In a presently contemplated implementation, when it is desired to read-out data from the implantable cardiac therapy device and/or to re-program the device parameters, a telemetry operation is attempted in the normal manner, i.e., it is initiated by the programming wand. If the communication is unsuccessful, then the direction of the magnetic field produced by the transmit coil of the programming wand is reversed, and the telemetry operation repeated. If the transmission of command data from the programming wand to the implantable cardiac therapy device is successful, but the transmission of read-out data from the device to the programming wand is unsuccessful, then the direction of current detection of the telemetry circuitry of the programming wand is reversed, and the telemetry operation is attempted again; alternatively, the direction of the magnetic field produced by the T/R coil of the implantable cardiac therapy device can be reversed. Thus, no matter what the orientation of the device and external telemetry device, successful two-way telemetry between the device and the programming wand is possible. Thus, the telemetry can be considered "two-sided". In an alternative embodiment, the telemetry operation can be initiated by the implantable cardiac therapy device. In this case, if the communication is unsuccessful, then the direction of the magnetic field produced by the T/R coil of the device is reversed.
-
公开(公告)号：US5609618A
公开(公告)日：1997-03-11
申请号：US568036
申请日：1995-12-06
申请人： Stephen T. Archer
发明人： Stephen T. Archer
CPC分类号： A61N1/3943 , A61N1/385
摘要： A method and apparatus for inducing fibrillation in a patient's heart by delivering an alternating current stimulus to the heart from a DC-to DC converter. The hardware of a conventional implantable cardioverter/defibrillator (ICD) is utilized with a modification to the control algorithms. Particularly, when it is desired to induce fibrillation in a patient's heart, typically during ICD implant defibrillation threshold (DFT) testing, a command is delivered from an external instrument to the ICD to deliver the fibrillation shock. The DC-to-DC converter which is normally used to charge the ICD high voltage capacitors is activated and immediately thereafter a first pair the high voltage output switches of the output stage are closed for about 4 milliseconds. This delivers an initial pulse of one polarity. Following an interval of about 4 milliseconds, a second pair of the high voltage output switches are closed for 4 milliseconds delivering an opposite polarity pulse. The output current from the DC-to-DC converter is provided to the defibrillation electrodes and through the patient's heart. This stimulus of alternating polarity pulses is continued for a predetermined time of between about 30 milliseconds to 5 seconds. At that point all the output switches are opened and the converter is shut off. This stimulus delivered directly to the patient's heart induces fibrillation.
摘要翻译： 一种用于通过从DC到DC转换器向心脏递送交流电刺激来在患者心脏中诱导原纤维颤动的方法和装置。 传统的植入式心律转复除颤器（ICD）的硬件被用于控制算法的修改。 特别地，当期望在患者心脏中诱发纤维颤动时，通常在ICD植入物除颤阈值（DFT）测试期间，将命令从外部仪器传送至ICD以递送原纤维颤动。 通常用于对ICD高电压电容器充电的DC-DC转换器被激活，并且紧接着，第一对输出级的高电压输出开关闭合约4毫秒。 这提供了一个极性的初始脉冲。 在大约4毫秒的间隔之后，第二对高电压输出开关闭合4毫秒，传递相反的极性脉冲。 来自DC-DC转换器的输出电流被提供给除颤电极并通过患者的心脏。 交替极性脉冲的刺激持续约30毫秒至5秒的预定时间。 此时，所有输出开关都打开，转换器关闭。 这种直接传递给患者心脏的刺激会诱发纤维颤动。
-
9.发明申请公开(公告)号：US20130261706A1
公开(公告)日：2013-10-03
申请号：US13444683
申请日：2012-04-11
申请人： Emily A. MIRRO , Stephen T. Archer
发明人： Emily A. MIRRO , Stephen T. Archer
IPC分类号： A61N1/36
CPC分类号： A61N1/36185 , A61N1/36064 , A61N1/36178
摘要： Described herein are methods and systems for delivering a burst of stimulation pulses or pulse segments sequentially to a plurality of stimulation pathways. The stimulation pulses may be generated by a stimulation device, which may comprise an implantable neurostimulator. The stimulation pathways may comprise one or more electrodes electrically connected to the stimulation device. In some variations, the stimulation pathway may comprise a monopolar stimulation pathway and/or a bipolar stimulation pathway.
摘要翻译： 这里描述了用于将刺激脉冲或脉冲段的脉冲序列顺序地递送到多个刺激通路的方法和系统。 刺激脉冲可以由刺激装置产生，刺激装置可以包括可植入的神经刺激器。 刺激途径可以包括电连接到刺激装置的一个或多个电极。 在一些变型中，刺激途径可以包括单极刺激途径和/或双极刺激途径。
-
公开(公告)号：US5431684A
公开(公告)日：1995-07-11
申请号：US172510
申请日：1993-12-22
CPC分类号： A61N1/3931 , A61N1/3912
摘要： A method and apparatus for testing the integrity of biphasic and monophasic defibrillator switches in an implantable defibrillator without delivering a shock to the patient. The test circuitry is integrated with and implantable with the defibrillator and provides for the testing of the defibrillator switches without shocking the patient by charging the capacitive defibrillation voltage source to a predetermined level and discharging it through a resistive network and shunting one of the switches to provide an alternate current path to ground, while isolating the test circuitry from the patient. Switch conditions are capable of ascertainment by measuring residual charge, i.e., voltage, on the capacitive voltage source at selected measurement times.
摘要翻译： 一种用于测试可植入除颤器中的双相和单相除颤器开关的完整性的方法和装置，而不会给患者带来冲击。 测试电路与除颤器集成并可植入，并且提供对除颤器开关的测试，而不会通过将电容式除颤电压源充电到预定水平并将其放电通过电阻网络并分流其中一个开关来提供患者，以提供 将测试电路与患者隔离的地电路径。 开关条件能够通过在所选择的测量时间测量电容性电压源上的剩余电荷即电压来确定。
-
-
-
-
-
-
-
-
-
搜索结果
16 条记录 (耗时 0.042 秒)
