公开(公告)号：US07437139B2

公开(公告)日：2008-10-14

申请号：US11258701

申请日：2005-10-26

申请人： Steve Lo ,  Isaac Sever ,  Thai Nguyen ,  Ssu-Pin Ma

发明人： Steve Lo ,  Isaac Sever ,  Thai Nguyen ,  Ssu-Pin Ma

IPC分类号： H04B1/16

CPC分类号： H04B1/1027

摘要： A method and apparatus of calibrating filtering of receive and transmit signals is disclosed. The method of calibrating filtering of a received signal includes injecting an LO signal. The injected LO signal is filtered by a tunable filter. The filtered signal is frequency down-converted with an equivalent LO signal. The frequency down-converted signal is sampled while tuning the filtering. A desired filter tuning is determined based upon the samples and a frequency of the LO signal. The method of calibrating filtering of a transmit signal includes injecting an LO signal to a transmitter. The LO signal is filtered by a tunable filter. The filtered signal is frequency down-converted with an equivalent LO signal. The frequency down-converted signal is sampled while tuning the filter. A desired filter tuning is determined based upon the samples and a frequency of the LO signal.

摘要翻译： 公开了一种校准接收和发送信号的滤波的方法和装置。 对接收信号进行校准滤波的方法包括：注入LO信号。 注入的LO信号被可调滤波器滤波。 滤波后的信号用等效的LO信号进行降频转换。 在对滤波进行调谐的同时对降频转换信号进行采样。 基于样本和LO信号的频率来确定期望的滤波器调谐。 校准发射信号的滤波的方法包括将LO信号注射到发射机。 LO信号由可调谐滤波器滤波。 滤波后的信号用等效的LO信号进行降频转换。 在对滤波器进行调谐的同时采样降频转换信号。 基于样本和LO信号的频率来确定期望的滤波器调谐。

公开(公告)号：US20070093224A1

公开(公告)日：2007-04-26

申请号：US11258701

申请日：2005-10-26

申请人： Steve Lo ,  Isaac Sever ,  Thai Nguyen ,  Ssu-Pin Ma

发明人： Steve Lo ,  Isaac Sever ,  Thai Nguyen ,  Ssu-Pin Ma

IPC分类号： H04B1/06

CPC分类号： H04B1/1027

摘要： A method and apparatus of calibrating filtering of receive and transmit signals is disclosed. The method of calibrating filtering of a received signal includes injecting an LO signal. The injected LO signal is filtered by a tunable filter. The filtered signal is frequency down-converted with an equivalent LO signal. The frequency down-converted signal is sampled while tuning the filtering. A desired filter tuning is determined based upon the samples and a frequency of the LO signal. The method of calibrating filtering of a transmit signal includes injecting an LO signal to a transmitter. The LO signal is filtered by a tunable filter. The filtered signal is frequency down-converted with an equivalent LO signal. The frequency down-converted signal is sampled while tuning the filter. A desired filter tuning is determined based upon the samples and a frequency of the LO signal.

摘要翻译： 公开了一种校准接收和发送信号的滤波的方法和装置。 对接收信号进行校准滤波的方法包括：注入LO信号。 注入的LO信号被可调滤波器滤波。 滤波后的信号用等效的LO信号进行降频转换。 在对滤波进行调谐的同时对降频转换信号进行采样。 基于样本和LO信号的频率来确定期望的滤波器调谐。 校准发射信号的滤波的方法包括将LO信号注射到发射机。 LO信号由可调谐滤波器滤波。 滤波后的信号用等效的LO信号进行降频转换。 在对滤波器进行调谐的同时采样降频转换信号。 基于样本和LO信号的频率来确定期望的滤波器调谐。

公开(公告)号：US20090253389A1

公开(公告)日：2009-10-08

申请号：US12061491

申请日：2008-04-02

申请人： Ssu-Pin Ma ,  Thai Nguyen ,  Feipeng Wang

发明人： Ssu-Pin Ma ,  Thai Nguyen ,  Feipeng Wang

IPC分类号： H04B1/04

CPC分类号： H04B1/0483 ,  H03F1/02 ,  H03F1/0222 ,  H03F1/0288 ,  H03F1/3241 ,  H03F1/565 ,  H03F3/24 ,  H04B2001/045

摘要： A technique for efficient power amplification includes providing multiple baseband signals to an amplifier. The signals may be converted to RF and combined through one or more impedance inverters.

摘要翻译： 用于高效功率放大的技术包括向放大器提供多个基带信号。 信号可以转换成RF并通过一个或多个阻抗逆变器组合。

公开(公告)号：US08180304B2

公开(公告)日：2012-05-15

申请号：US12061491

申请日：2008-04-02

申请人： Ssu-Pin Ma ,  Thai Nguyen ,  Feipeng Wang

发明人： Ssu-Pin Ma ,  Thai Nguyen ,  Feipeng Wang

IPC分类号： H04B1/04

CPC分类号： H04B1/0483 ,  H03F1/02 ,  H03F1/0222 ,  H03F1/0288 ,  H03F1/3241 ,  H03F1/565 ,  H03F3/24 ,  H04B2001/045

摘要： A technique for efficient power amplification includes providing multiple baseband signals to an amplifier. The signals may be converted to RF and combined through one or more impedance inverters.

摘要翻译： 用于高效功率放大的技术包括向放大器提供多个基带信号。 信号可以转换成RF并通过一个或多个阻抗逆变器组合。

公开(公告)号：US07524849B2

公开(公告)日：2009-04-28

申请号：US10950375

申请日：2004-09-24

申请人： Nan Zhang ,  Semiramis Ayral-Kaloustian ,  Thai Nguyen

发明人： Nan Zhang ,  Semiramis Ayral-Kaloustian ,  Thai Nguyen

IPC分类号： C07D239/42 ,  C07D239/48 ,  A61K31/505

CPC分类号： C07D239/42 ,  A61K31/505 ,  A61K31/506 ,  C07D239/48 ,  C07D401/04 ,  C07D403/04 ,  C07D405/04 ,  C07D409/04

摘要： This invention relates to certain 5-arylpyrimidine compounds or a pharmaceutically acceptable salt thereof, and compositions containing said compounds or a pharmaceutically acceptable salt thereof, wherein said compounds are anti-cancer agents useful for the treatment of cancer in mammals. This invention further relates to a method of treating or inhibiting the growth of cancerous tumor cells and associated diseases in a mammal and further provides a method for the treatment or prevention of cancerous tumors that express multiple drug resistance (MDR) or are resistant because of MDR, in a mammal in need thereof which method comprises administering to said mammal an effective amount of said compounds or a pharmaceutically acceptable salt thereof.More specifically, the present invention relates to a method of treating or inhibiting the growth of cancerous tumor cells and associated diseases in a mammal in need thereof by promotion of microtubule polymerization which comprises administering to said mammal an effective amount of said compounds and pharmaceutically acceptable salts thereof.

摘要翻译： 本发明涉及某些5-芳基嘧啶化合物或其药学上可接受的盐，以及含有所述化合物或其药学上可接受的盐的组合物，其中所述化合物是可用于治疗哺乳动物癌症的抗癌剂。 本发明还涉及治疗或抑制哺乳动物中癌性肿瘤细胞和相关疾病的生长的方法，并进一步提供了治疗或预防表达多重耐药性（MDR）或耐多药耐药性的癌性肿瘤的方法 在需要的哺乳动物中，所述方法包括向所述哺乳动物施用有效量的所述化合物或其药学上可接受的盐。 更具体地，本发明涉及通过促进微管聚合来治疗或抑制有需要的哺乳动物中癌性肿瘤细胞和相关疾病的生长的方法，其包括向所述哺乳动物施用有效量的所述化合物和药学上可接受的盐 其中。

公开(公告)号：US07350101B1

公开(公告)日：2008-03-25

申请号：US10329222

申请日：2002-12-23

申请人： Thai Nguyen ,  Charles A. Milligan ,  Michael L. Leonhardt ,  Stephen S. Selkirk ,  Gerald O'Nions ,  James P. Hughes

发明人： Thai Nguyen ,  Charles A. Milligan ,  Michael L. Leonhardt ,  Stephen S. Selkirk ,  Gerald O'Nions ,  James P. Hughes

IPC分类号： G06F11/00

CPC分类号： G06F11/1084 ,  G06F2211/108

摘要： A method, computer program product, and data processing system for continuously writing new data to a redundant array of independent storage devices without interrupting the writing of new data to the array to reconstruct missing data from a failed device or failed media is disclosed. A fault-tolerance scheme using multiple independent parity values is used to record data to the array. In the event that one of the volumes in the array fails, the remaining volumes continue being written to, but with fewer data or parity values being employed. The failed volume can then be reconstructed following the completion of writing the media set currently being written.

摘要翻译： 公开了一种方法，计算机程序产品和数据处理系统，用于将新数据连续地写入独立存储设备的冗余阵列，而不会中断将数据写入阵列以从故障设备或故障介质重新构建丢失的数据。 使用多个独立奇偶校验值的容错方案用于将数据记录到阵列。 如果阵列中的一个卷失败，剩余的卷将继续写入，但采用的数据或奇偶校验值较少。 完成写入当前正在写入的媒体集之后，可以重构失败的音量。

公开(公告)号：US20050075357A1

公开(公告)日：2005-04-07

申请号：US10950375

申请日：2004-09-24

申请人： Nan Zhang ,  Semiramis Ayral-Kaloustian ,  Thai Nguyen

发明人： Nan Zhang ,  Semiramis Ayral-Kaloustian ,  Thai Nguyen

IPC分类号： A61K31/505 ,  A61K31/506 ,  A61P35/00 ,  C07D239/42 ,  C07D239/48 ,  C07D401/04 ,  C07D403/04 ,  C07D405/04 ,  C07D409/04 ,  A61K31/513 ,  C07D43/02

CPC分类号： C07D239/42 ,  A61K31/505 ,  A61K31/506 ,  C07D239/48 ,  C07D401/04 ,  C07D403/04 ,  C07D405/04 ,  C07D409/04

摘要： This invention relates to certain 5-arylpyrimidine compounds or a pharmaceutically acceptable salt thereof, and compositions containing said compounds or a pharmaceutically acceptable salt thereof, wherein said compounds are anti-cancer agents useful for the treatment of cancer in mammals. This invention further relates to a method of treating or inhibiting the growth of cancerous tumor cells and associated diseases in a mammal and further provides a method for the treatment or prevention of cancerous tumors that express multiple drug resistance (MDR) or are resistant because of MDR, in a mammal in need thereof which method comprises administering to said mammal an effective amount of said compounds or a pharmaceutically acceptable salt thereof. More specifically, the present invention relates to a method of treating or inhibiting the growth of cancerous tumor cells and associated diseases in a mammal in need thereof by promotion of microtubule polymerization which comprises administering to said mammal an effective amount of said compounds and pharmaceutically acceptable salts thereof.

摘要翻译： 本发明涉及某些5-芳基嘧啶化合物或其药学上可接受的盐，以及含有所述化合物或其药学上可接受的盐的组合物，其中所述化合物是可用于治疗哺乳动物癌症的抗癌剂。 本发明还涉及治疗或抑制哺乳动物中癌性肿瘤细胞和相关疾病的生长的方法，并进一步提供了治疗或预防表达多重耐药性（MDR）或耐多药耐药性的癌性肿瘤的方法 在需要的哺乳动物中，所述方法包括向所述哺乳动物施用有效量的所述化合物或其药学上可接受的盐。 更具体地，本发明涉及通过促进微管聚合来治疗或抑制有需要的哺乳动物中癌性肿瘤细胞和相关疾病的生长的方法，其包括向所述哺乳动物施用有效量的所述化合物和药学上可接受的盐 其中。

公开(公告)号：US06658526B2

公开(公告)日：2003-12-02

申请号：US09421916

申请日：1999-10-20

申请人： Thai Nguyen ,  Robert M. Raymond ,  Michael L. Leonhardt

发明人： Thai Nguyen ,  Robert M. Raymond ,  Michael L. Leonhardt

IPC分类号： G06F1200

CPC分类号： G06F3/0613 ,  G06F3/0664 ,  G06F3/067 ,  G06F3/0686

摘要： This data storage subsystem creates multiple virtual storage devices on demand, which are available to any and all of the system's host data processors. The subsystem utilizes a plurality of tape devices and automated tape libraries with the tape devices connected to a plurality of data processors via a high-speed network. A set of software components, the Network Storage Manager (NSM) controls all system operations. Depending upon the requested storage performance, one or more tape devices are assigned to a virtual device. Data stripping across multiple tape devices allows the storage bandwidth of a virtual device to be changed on demand. The overall capacity and performance of the subsystem is scalable by adding or removing storage devices. The NSM system controller contains a plurality of software elements including: Resource Allocation, Resource Configuration, Resource Management, and Security Management modules. The use of a networked storage manager enables the storage devices to be managed as a pool and yet be attached directly to the network as individual resources. The NSM also provides the mechanism for the enterprise management to control tape device allocation and configuration as well as other functions, such as tape cartridge movement, data migration and data security.

摘要翻译： 该数据存储子系统根据需要创建多个虚拟存储设备，可用于任何和所有系统的主机数据处理器。 子系统利用多个磁带设备和自动磁带库，磁带设备经由高速网络连接到多个数据处理器。 一组软件组件，网络存储管理器（NSM）控制所有系统操作。 根据请求的存储性能，将一个或多个磁带设备分配给虚拟设备。 跨多个磁带设备的数据剥离允许虚拟设备的存储带宽根据需求进行更改。 通过添加或删除存储设备可以扩展子系统的整体容量和性能。 NSM系统控制器包含多个软件元素，包括：资源分配，资源配置，资源管理和安全管理模块。 使用网络存储管理器可以将存储设备作为池进行管理，并将其作为个别资源直接连接到网络。 NSM还提供了企业管理控制磁带设备分配和配置以及其他功能（如磁带盒移动，数据迁移和数据安全性）的机制。

公开(公告)号：US06529996B1

公开(公告)日：2003-03-04

申请号：US09343512

申请日：1999-06-30

申请人： Thai Nguyen ,  Robert Michael Raymond ,  Michael Lawrence Leonhardt

发明人： Thai Nguyen ,  Robert Michael Raymond ,  Michael Lawrence Leonhardt

IPC分类号： G06F1200

CPC分类号： G11B15/68 ,  G06F3/0626 ,  G06F3/0664 ,  G06F3/067

摘要： The network attached virtual tape storage subsystem interconnects a plurality of tape devices with a plurality of data processors via a high bandwidth switching network to implement a virtual, distributed tape data storage subsystem. The virtual, distributed tape data storage system realizes multiple virtual devices, which are available to any of the data processors and the bandwidth of the system is scalable and can be changed on demand. The virtual tape storage subsystem is managed by a system controller which contains a plurality of software elements including: resource allocation, resource configuration, and resource management. The use of a networked storage manager enables the tape devices to be managed as a pool and yet attach the tape devices directly to the network as individual resources. The networked storage manager must provide the mechanism for the enterprise management to control tape device allocation and configuration as well as other functions, such as tape cartridge movement and data migration.

摘要翻译： 网络连接的虚拟磁带存储子系统通过高带宽交换网络将多个磁带设备与多个数据处理器互连，以实现虚拟的分布式磁带数据存储子系统。 虚拟分布式磁带数据存储系统实现多个虚拟设备，这些虚拟设备可用于任何数据处理器，并且系统的带宽是可扩展的，可以根据需要进行更改。 虚拟磁带存储子系统由包含多个软件元素的系统控制器管理，包括：资源分配，资源配置和资源管理。 使用网络存储管理器可以将磁带设备作为池进行管理，并将磁带设备作为个别资源直接附加到网络。 网络存储管理器必须提供企业管理机制来控制磁带设备分配和配置以及其他功能，如磁带盒移动和数据迁移。

公开(公告)号：US06310342B1

公开(公告)日：2001-10-30

申请号：US09128885

申请日：1998-08-04

申请人： David Braunstein ,  Michael Kirk ,  Quoc Ly ,  Thai Nguyen

发明人： David Braunstein ,  Michael Kirk ,  Quoc Ly ,  Thai Nguyen

IPC分类号： H01J3720

CPC分类号： G01Q10/04 ,  G01Q30/025 ,  Y10S977/849 ,  Y10S977/86 ,  Y10S977/868 ,  Y10S977/869 ,  Y10S977/87 ,  Y10S977/872 ,  Y10S977/873

摘要： Scanning probe microscopes and scanning probe heads are provided having improved optical visualization and sample manipulation capabilities. The SPMs and SPM heads include at least one flexure stage for scanning in the x, y and/or z directions. In a preferred embodiment, the SPMs or SPM heads include flexure stages for scanning in the x, y and z directions. The z scanning stage is preferably positioned outside the lateral footprint of the x-y flexure stage so that a probe extending from the z scanning stage is outside the lateral footprint of the instrument. The SPMs and SPM heads are configured to provide top down and bottom up optical views of the sample and/or the probe and enable simultaneous scanning probe microscopy and optical imaging of a sample to be performed. The SPMs and SPM heads are designed to be readily combinable with existing upright and inverted optical microscopes currently available from various major manufacturers.

摘要翻译： 提供扫描探针显微镜和扫描探头，具有改进的光学可视化和样品操作能力。 SPM和SPM头包括用于在x，y和/或z方向扫描的至少一个弯曲台。 在优选实施例中，SPM或SPM头包括用于在x，y和z方向扫描的挠曲台。 z扫描台优选地定位在x-y弯曲台的横向覆盖区的外侧，使得从z扫描台延伸的探针位于仪器的横向覆盖区之外。 SPM和SPM头被配置为提供样品和/或探针的自顶向下和从底部的光学视图，并且能够执行样品的同时扫描探针显微镜和光学成像。 SPM和SPM头设计为可以与现有的各种主要制造商现有的直立和倒置光学显微镜组合。