摘要:
The present invention relates to an oral composition comprising a soluble fluoride ion source, tetrasodium pyrophosphate, calcium peroxide, one or more nonionic surfactants and/or amphoteric surfactants, and one or more aqueous carriers; wherein the oral composition has a neat pH of from about 9.0 to about 10.5 and a total water content of from about 5% to about 20%. The invention may also include polyethylene glycol, an alkali metal bicarbonate salt, and xylitol.
摘要:
The present invention relates to a method of manufacturing predominately undissolved pyrophosphate and calcium peroxide compositions comprising the steps of: (a) preparing a mixture of a soluble fluoride ion source and one or more aqueous carrier materials; (b) adding tetrasodium pyrophosphate and calcium peroxide, all at once or in portions, under conditions wherein less than about 20% of the total pyrophosphate and calcium peroxide are dissolved in the mixture, and wherein any further remaining aqueous carrier materials not added to the mixtures during step (a) are added in whole or in part in step (b) or thereafter, either by themselves or with any remaining amount of the tetrasodium pyrophosphate or calcium peroxide under conditions such that less then about 20% of the total pyrophosphate and calcium peroxide are dissolved in the mixture; and (c) heating the mixture.
摘要:
The present invention relates to an oral compositions comprising a soluble fluoride ion source, tetrasodium pyrophosphate, calcium peroxide, and one or more aqueous carriers, wherein the oral composition has a neat pH of from about 9.0 to about 10.5 and a total water content of from about 9.1% to about 20%. The invention may also include an alkali metal bicarbonate salt and xylitol.
摘要:
The method of manufacturing comprises the steps of: (a) preparing a mixture of a favor system, one or more humectants, and one or more aqueous carrier materials; (b) adding tetrasodium pyrophosphate and calcium peroxide, all at once or in portions, under conditions wherein less than about 20% of the total pyrophosphate and calcium peroxide are dissolved in the mixture; and wherein further any remaining aqueous carrier materials not added to the mixture during step (a) are added in whole or in part in step (b) or thereafter, either by themselves or with any remaining amount of the tetrasodium pyrophosphate or calcium peroxide, under conditions such that less than about 20% of the total pyrophosphate and calcium peroxide are dissolved in the mixture; (c) heating the mixture to a temperature range of from about 38.degree. C. (100.degree. F.) to about 71.degree. C. (160.degree. F.) and preferably to a temperature range of from about 52.degree. C. (125.degree. F.) to about 57.degree. C. (135.degree. F.), and (d) homogenizing the mixture in the temperature range for about 15 minutes to about 60 minutes. The tetrasodium pyrophosphate salt and peroxide are two of the last components to be added to the mixture, preferably after all or much of the other sodium-containing salts present in the composition have been added to the process mixture. By these methods, the dissolved tetrasodium pyrophosphate salt is less likely to recrystalize in the form of glass-like crystal particles of tetrasodium pyrophosphate decahydrate.
摘要:
Stable topical oral compositions comprising at least a minimally effective amount of chlorite ion are disclosed, wherein the pH of the final composition is greater than 7, the composition is essentially free of chlorine dioxide, and the composition is stable against loss of chlorite for a period of at least one year under normal storage conditions at about 25° C. or for a period of 3 months under accelerated storage conditions at about 40° C. Preferably the compositions further comprise a flavor system, which is stable against degradation by chlorite. The compositions are formulated as therapeutic rinses, especially mouth rinses, as well as toothpastes, gels, tooth powders, chewing gums, mouth sprays, lozenges (including breath mints), dental implements (such as dental floss and tape), and pet care products.
摘要:
Disclosed is a composition for delivering an oral care substance to the oral cavity, comprising: (a) an organosiloxane resin; (b) a volatile carrier capable of solubilizing the organosiloxane resin; (c) a rheology modifier; and (d) at least one oral care substance. The present invention is also directed to such compositions comprising: (a) an organosiloxane resin; (b) a fluid diorganopolysiloxane polymer; (c) a volatile carrier capable of solubilizing the organosiloxane resin and the fluid diorganopolysiloxane polymer; (d) a rheology modifier; and (e) at least one oral care substance. Further disclosed is a method of using these compositions
摘要:
Disclosed are oral compositions comprising a nonionic surfactant and/or amphoteric surfactant, an anionic surfactant, free pyrophosphate ions or tetrasodium pyrophosphate, free fluoride ions, and one or more aqueous carriers. The compositions may also contain an alkali metal bicarbonate salt and xylitol.
摘要:
Topical compositions containing from about 40% to about 77% by weight of the composition of a humectant component, said component containing from about 0.25% to about 7% of a structuring humectant selected from polyethylene glycols having an average molecular weight of from about 3,000 to about 8,000, and mixtures thereof; and at least one secondary humectant; the topical composition further comprises abrasive from about 5% to about 35%; from about 0% to about 1.5% of a viscosity modifier; a total solids content of 50% or less; water from about 5% to about 12%; and wherein the structuring humectant is added to the composition in solution with solvent or is added in a controlled manner as a molten material to the composition at a temperature less than about 35° C. and with turbulent mixing or vigorous agitation.
摘要:
Topical compositions containing from about 40% to about 77% by weight of the composition of a humectant component, said component containing from about 0.25% to about 7% of a structuring humectant selected from polyethylene glycols having an average molecular weight of from about 3,000 to about 8,000, and mixtures thereof; and at least one secondary humectant; the topical composition further comprises abrasive from about 5% to about 35%; from about 0% to about 1.5% of a viscosity modifier; a total solids content of 50% or less; water from about 5% to about 12%; and wherein the structuring humectant is added to the composition in solution with solvent or is added in a controlled manner as a molten material to the composition at a temperature less than about 35° C. and with turbulent mixing or vigorous agitation.
摘要:
Disclosed is a composition for delivering an oral care substance to the oral cavity, comprising: (a) an organosiloxane resin; (b) a volatile carrier capable of solubilizing the organosiloxane resin; (c) a rheology modifier; and (d) at least one oral care substance. The present invention is also directed to such compositions comprising: (a) an organosiloxane resin; (b) a fluid diorganopolysiloxane polymer; (c) a volatile carrier capable of solubilizing the organosiloxane resin and the fluid diorganopolysiloxane polymer; (d) a rheology modifier; and (e) at least one oral care substance. Further disclosed is a method of using these compositions.