Method of making a tartar control dentifrice containing fluoride and
peroxide
    2.
    发明授权
    Method of making a tartar control dentifrice containing fluoride and peroxide 失效
    制造含有氟化物和过氧化物的牙垢控制洁齿剂的方法

    公开(公告)号:US5776437A

    公开(公告)日:1998-07-07

    申请号:US756995

    申请日:1996-11-26

    CPC分类号: A61Q11/00 A61K8/22 A61K8/24

    摘要: The present invention relates to a method of manufacturing predominately undissolved pyrophosphate and calcium peroxide compositions comprising the steps of: (a) preparing a mixture of a soluble fluoride ion source and one or more aqueous carrier materials; (b) adding tetrasodium pyrophosphate and calcium peroxide, all at once or in portions, under conditions wherein less than about 20% of the total pyrophosphate and calcium peroxide are dissolved in the mixture, and wherein any further remaining aqueous carrier materials not added to the mixtures during step (a) are added in whole or in part in step (b) or thereafter, either by themselves or with any remaining amount of the tetrasodium pyrophosphate or calcium peroxide under conditions such that less then about 20% of the total pyrophosphate and calcium peroxide are dissolved in the mixture; and (c) heating the mixture.

    摘要翻译: 本发明涉及主要生产未溶解的焦磷酸盐和过氧化钙组合物的方法,包括以下步骤:(a)制备可溶性氟离子源和一种或多种含水载体材料的混合物; (b)在其中少于约20%的焦磷酸钙和过氧化钙溶解在混合物中的条件下,一次或分批加入焦磷酸四钠和过氧化钙,并且其中任何进一步的剩余的水性载体材料未加入到 在步骤(a)中的混合物在步骤(b)或之后全部或部分地加入,或者在其自身或任何剩余量的焦磷酸四钠或过氧化钙的条件下加入,使得少于总焦磷酸盐的约20% 过氧化钙溶解在混合物中; 和(c)加热混合物。

    Process for increased flavor impact in oral care products
    4.
    发明授权
    Process for increased flavor impact in oral care products 失效
    在口腔护理产品中增加风味影响的方法

    公开(公告)号:US5811080A

    公开(公告)日:1998-09-22

    申请号:US756450

    申请日:1996-11-26

    摘要: The method of manufacturing comprises the steps of: (a) preparing a mixture of a favor system, one or more humectants, and one or more aqueous carrier materials; (b) adding tetrasodium pyrophosphate and calcium peroxide, all at once or in portions, under conditions wherein less than about 20% of the total pyrophosphate and calcium peroxide are dissolved in the mixture; and wherein further any remaining aqueous carrier materials not added to the mixture during step (a) are added in whole or in part in step (b) or thereafter, either by themselves or with any remaining amount of the tetrasodium pyrophosphate or calcium peroxide, under conditions such that less than about 20% of the total pyrophosphate and calcium peroxide are dissolved in the mixture; (c) heating the mixture to a temperature range of from about 38.degree. C. (100.degree. F.) to about 71.degree. C. (160.degree. F.) and preferably to a temperature range of from about 52.degree. C. (125.degree. F.) to about 57.degree. C. (135.degree. F.), and (d) homogenizing the mixture in the temperature range for about 15 minutes to about 60 minutes. The tetrasodium pyrophosphate salt and peroxide are two of the last components to be added to the mixture, preferably after all or much of the other sodium-containing salts present in the composition have been added to the process mixture. By these methods, the dissolved tetrasodium pyrophosphate salt is less likely to recrystalize in the form of glass-like crystal particles of tetrasodium pyrophosphate decahydrate.

    摘要翻译: 制造方法包括以下步骤:(a)制备有利系统,一种或多种湿润剂和一种或多种含水载体材料的混合物; (b)在其中少于约20%的焦磷酸钙和过氧化钙溶解在混合物中的条件下,一次或分批加入焦磷酸四钠和过氧化钙, 并且其中在步骤(a)中没有添加到混合物中的任何剩余的水性载体材料在步骤(b)或之后全部或部分地加入,或者单独或任何剩余量的焦磷酸四钠或过氧化钙在下面 条件使得少于约20%的焦磷酸钙和过氧化钙溶解在混合物中; (c)将混合物加热至约38℃(100°F)至约71℃(160°F)的温度范围,优选至约52℃的温度范围(125 DEG)至约57℃(135°F),和(d)在约15分钟至约60分钟的温度范围内使混合物均化。 焦磷酸四钠盐和过氧化物是添加到混合物中的最后一种组分中的两种,优选在组合物中存在的所有或大部分其它含钠盐已经加入到工艺混合物中之后。 通过这些方法,溶解的焦磷酸四钠盐不太可能以焦磷酸四钠十水合物的玻璃状结晶颗粒的形式重结晶。

    Stable oral care compositions comprising chlorite
    5.
    发明授权
    Stable oral care compositions comprising chlorite 失效
    包含亚氯酸盐的稳定的口腔护理组合物

    公开(公告)号:US06696047B2

    公开(公告)日:2004-02-24

    申请号:US10218771

    申请日:2002-08-14

    IPC分类号: A61K716

    摘要: Stable topical oral compositions comprising at least a minimally effective amount of chlorite ion are disclosed, wherein the pH of the final composition is greater than 7, the composition is essentially free of chlorine dioxide, and the composition is stable against loss of chlorite for a period of at least one year under normal storage conditions at about 25° C. or for a period of 3 months under accelerated storage conditions at about 40° C. Preferably the compositions further comprise a flavor system, which is stable against degradation by chlorite. The compositions are formulated as therapeutic rinses, especially mouth rinses, as well as toothpastes, gels, tooth powders, chewing gums, mouth sprays, lozenges (including breath mints), dental implements (such as dental floss and tape), and pet care products.

    摘要翻译: 公开了包含至少最低有效量的亚氯酸根离子的稳定的局部口服组合物,其中最终组合物的pH大于7,组合物基本上不含二氧化氯,并且组合物对于亚氯酸盐的损失是稳定的 在约25℃的正常储存条件下至少一年,或在加速储存条件下在约40℃下持续3个月。优选地,组合物还包含风味系统,其对于亚氯酸盐降解是稳定的。 将组合物配制成治疗性漂洗剂,特别是漱口剂,以及牙膏,凝胶,牙粉,口香糖,口腔喷雾剂,锭剂(包括呼吸薄荷),牙科用具(例如牙线和胶带)和宠物护理产品 。

    Oral care compositions with improved rheology
    8.
    发明授权
    Oral care compositions with improved rheology 有权
    具有改善流变性的口腔护理组合物

    公开(公告)号:US08956593B2

    公开(公告)日:2015-02-17

    申请号:US13596719

    申请日:2012-08-28

    摘要: Topical compositions containing from about 40% to about 77% by weight of the composition of a humectant component, said component containing from about 0.25% to about 7% of a structuring humectant selected from polyethylene glycols having an average molecular weight of from about 3,000 to about 8,000, and mixtures thereof; and at least one secondary humectant; the topical composition further comprises abrasive from about 5% to about 35%; from about 0% to about 1.5% of a viscosity modifier; a total solids content of 50% or less; water from about 5% to about 12%; and wherein the structuring humectant is added to the composition in solution with solvent or is added in a controlled manner as a molten material to the composition at a temperature less than about 35° C. and with turbulent mixing or vigorous agitation.

    摘要翻译: 含有约40%至约77%重量的组合物湿润组分的局部组合物,所述组分含有约0.25%至约7%的结构化保湿剂,其选自平均分子量为约3,000至 约8,000,及其混合物; 和至少一个二次保湿剂; 局部组合物还包含约5%至约35%的磨料; 约0%至约1.5%的粘度改性剂; 总固体含量为50%以下; 约5%至约12%的水; 并且其中将结构化湿润剂在溶剂中用溶剂加入到组合物中,或者以受控的方式作为熔融材料加入到组合物中,在低于约35℃的温度下并且在湍流混合或剧烈搅拌下。

    ORAL CARE COMPOSITIONS WITH IMPROVED RHEOLOGY
    9.
    发明申请
    ORAL CARE COMPOSITIONS WITH IMPROVED RHEOLOGY 有权
    口腔护理组合物与改善的流变学

    公开(公告)号:US20130280182A1

    公开(公告)日:2013-10-24

    申请号:US13596719

    申请日:2012-08-28

    摘要: Topical compositions containing from about 40% to about 77% by weight of the composition of a humectant component, said component containing from about 0.25% to about 7% of a structuring humectant selected from polyethylene glycols having an average molecular weight of from about 3,000 to about 8,000, and mixtures thereof; and at least one secondary humectant; the topical composition further comprises abrasive from about 5% to about 35%; from about 0% to about 1.5% of a viscosity modifier; a total solids content of 50% or less; water from about 5% to about 12%; and wherein the structuring humectant is added to the composition in solution with solvent or is added in a controlled manner as a molten material to the composition at a temperature less than about 35° C. and with turbulent mixing or vigorous agitation.

    摘要翻译: 含有约40%至约77%重量的组合物湿润组分的局部组合物,所述组分含有约0.25%至约7%的结构化保湿剂,其选自平均分子量为约3,000至 约8,000,及其混合物; 和至少一个二次保湿剂; 局部组合物还包含约5%至约35%的磨料; 约0%至约1.5%的粘度改性剂; 总固体含量为50%以下; 约5%至约12%的水; 并且其中将结构化湿润剂在溶剂中用溶剂加入到组合物中,或者以受控的方式作为熔融材料加入到组合物中,在低于约35℃的温度下并且在湍流混合或剧烈搅拌下。

    Compositions comprising organosiloxane resins for delivering oral care substances
    10.
    发明授权
    Compositions comprising organosiloxane resins for delivering oral care substances 失效
    包含用于递送口腔护理物质的有机硅氧烷树脂的组合物

    公开(公告)号:US06589512B1

    公开(公告)日:2003-07-08

    申请号:US10019029

    申请日:2001-12-20

    IPC分类号: A61K716

    摘要: Disclosed is a composition for delivering an oral care substance to the oral cavity, comprising: (a) an organosiloxane resin; (b) a volatile carrier capable of solubilizing the organosiloxane resin; (c) a rheology modifier; and (d) at least one oral care substance. The present invention is also directed to such compositions comprising: (a) an organosiloxane resin; (b) a fluid diorganopolysiloxane polymer; (c) a volatile carrier capable of solubilizing the organosiloxane resin and the fluid diorganopolysiloxane polymer; (d) a rheology modifier; and (e) at least one oral care substance. Further disclosed is a method of using these compositions.

    摘要翻译: 公开了一种用于将口腔护理物质输送到口腔的组合物,其包含:(a)有机硅氧烷树脂; (b)能溶解有机硅氧烷树脂的挥发性载体; (c)流变改性剂; 和(d)至少一种口腔护理物质。 本发明还涉及这样的组合物,其包含:(a)有机硅氧烷树脂; (b)流体二有机聚硅氧烷聚合物; (c)能够溶解有机硅氧烷树脂和流体二有机聚硅氧烷聚合物的挥发性载体; (d)流变改性剂; 和(e)至少一种口腔护理物质。 进一步公开的是使用这些组合物的方法。