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    Compositions and methods for personal care
    1.
    发明申请
    Compositions and methods for personal care 审中-公开
    个人护理的组成和方法

    公开(公告)号：US20090246155A1

    公开(公告)日：2009-10-01

    申请号：US12455628

    申请日：2009-06-04

    申请人： Steven P. Bitler ,  Qiang Zheng ,  David Taft

    发明人： Steven P. Bitler ,  Qiang Zheng ,  David Taft

    IPC分类号： A61Q17/04 ,  A61K8/00 ,  A61Q15/00 ,  A61Q1/06 ,  A61Q1/00 ,  A61Q5/00 ,  A61Q3/00 ,  C11D3/00

    CPC分类号： A61Q19/00 ,  A61K8/85 ,  A61K2800/413 ,  A61K2800/54 ,  A61Q1/02 ,  A61Q1/06 ,  A61Q1/14 ,  A61Q5/06 ,  B82Y5/00

    摘要： Systems and methods for delivering personal care materials. Crystalline polymeric systems, referred to as CYC carriers, are associated with the cosmetic materials, through chemical bonding or through physical association. The crystallinity of the CYC carriers results from the presence of crystallizable side chains, for example long chain n-alkyl moieties, which results in relatively low and sharp melting temperatures. One class of CYC carriers, referred to as CYSC polymers, have a majority of the crystallizable side chains pendant from the polymer backbone. Another class of CYC carriers, referred to as ECC polymers, have a majority of the crystallizable side chains attached to terminal units of the polymer backbone. The ECC polymers can for example be obtained by modification of PLGA polymers. The CYC carriers in another class are non-polymeric. Some CYC carriers, referred to as CYC assemblies, have enhanced crystallinity as a result of the physical association of crystallizable moieties which are present in different types of molecule, for example between a polymer containing crystallizable moieties and a monomer containing crystallizable moieties. Preferably the CYC carrier is bioerodable.

    摘要翻译： 提供个人护理材料的系统和方法。 称为CYC载体的结晶聚合体系通过化学键合或通过物理缔合与化妆品材料相关联。 CYC载体的结晶度来自可结晶侧链的存在，例如长链正烷基部分，这导致相对低的和尖锐的熔融温度。 称为CYSC聚合物的一类CYC载体具有从聚合物主链悬挂的大部分可结晶侧链。 称为ECC聚合物的另一类CYC载体具有连接至聚合物主链末端单元的大部分可结晶侧链。 ECC聚合物可以例如通过改性PLGA聚合物来获得。 另一类的CYC载体是非聚合物。 一些称为CYC组件的CYC载体由于存在于不同类型分子中的可结晶部分的物理结合而具有增强的结晶度，例如在含可结晶部分的聚合物和含可结晶部分的单体之间。 CYC载体优选是可生物侵蚀的。

    Compositions and Methods for Delivery of Materials
    2.
    发明申请
    Compositions and Methods for Delivery of Materials 审中-公开
    材料交付的组成和方法

    公开(公告)号：US20120088659A1

    公开(公告)日：2012-04-12

    申请号：US13376191

    申请日：2010-06-04

    申请人： David Taft ,  Steven Bitler ,  Qiang Zheng ,  Natarajan Balanchander ,  Damian Hadjuk

    发明人： David Taft ,  Steven Bitler ,  Qiang Zheng ,  Natarajan Balanchander ,  Damian Hadjuk

    IPC分类号： A61K47/32 ,  A01N25/10 ,  A61K8/02 ,  A01N25/26 ,  A61K8/81 ,  A61K9/00 ,  B82Y30/00 ,  B82Y5/00

    CPC分类号： A01N25/28 ,  A01N25/10 ,  A01N25/12 ,  A01N51/00

    摘要： Compositions for the controlled delivery of active ingredients, for example, drugs, cosmetic materials, and agricultural materials. The compositions include a multiplicity of particles, each of the particles comprising (1) a microstructure comprising a semicrystalline polymer which has a peak melting temperature, Tp, of at least 20° C., and (2) the active ingredient. The microstructure comprises (i) crystalline domains of the semicrystalline polymer, the crystalline domains being separate from each other, and (ii) amorphous domains of the semicrystalline polymer, the amorphous domains providing a multiplicity of tortuous paths between the crystalline domains. At least part of the active ingredient is present in the amorphous domains. One of many valuable uses for the compositions is to provide a coating on a seed, for example a coating containing one or more of an insecticide, a fungicide, a nutrient, a biotic, a growth regulator and an herbicide.

    摘要翻译： 用于控制递送活性成分的组合物，例如药物，化妆品材料和农业材料。 组合物包括多个颗粒，每个颗粒包含（1）包含半结晶聚合物的微结构，其具有至少20℃的峰值熔融温度Tp，和（2）活性成分。 微结构包括（i）半结晶聚合物的结晶域，结晶域彼此分离，和（ii）半结晶聚合物的无定形区域，非晶畴在晶畴之间提供多个曲折的路径。 至少部分活性成分存在于无定形区域中。 组合物的许多有价值的用途之一是在种子上提供涂层，例如包含杀虫剂，杀真菌剂，营养物，生物，生长调节剂和除草剂中的一种或多种的涂层。

    Systems and methods for delivery of drugs
    3.
    发明申请
    Systems and methods for delivery of drugs 审中-公开
    用于输送药物的系统和方法

    公开(公告)号：US20090263346A1

    公开(公告)日：2009-10-22

    申请号：US12315876

    申请日：2008-12-04

    申请人： David Taft ,  Steven Bitler ,  Qiang Zheng ,  Stelios Tzannis ,  Adam Bell ,  Wei-Guo Dai ,  Sandra Ottensmann

    发明人： David Taft ,  Steven Bitler ,  Qiang Zheng ,  Stelios Tzannis ,  Adam Bell ,  Wei-Guo Dai ,  Sandra Ottensmann

    IPC分类号： A61K47/48 ,  A61P25/18

    CPC分类号： A61K9/146 ,  A61K9/0019 ,  A61K9/0024

    摘要： Systems and methods for delivering drugs. Crystalline polymeric systems, referred to as CYC carriers, are associated with the drugs, through chemical bonding or through physical association. The crystallinity of the CYC carriers results from the presence of crystallizable side chains, for example long chain n-alkyl moieties, which results in relatively low and sharp melting temperatures. One class of CYC carriers, referred to as CYSC polymers, have a majority of the crystallizable side chains pendant from the polymer backbone. Another class of CYC carriers, referred to as ECC polymers, have a majority of the crystallizable side chains attached to terminal units of the polymer backbone. The ECC polymers can for example be obtained by modification of PLGA polymers. The CYC carriers in another class are non-polymeric. Some CYC carriers, referred to as CYC assemblies, have enhanced crystallinity as a result of the physical association of crystallizable moieties which are present in different types of molecule, for example between a polymer containing crystallizable moieties and a monomer containing crystallizable moieties. Preferably the CYC carrier is bioerodable.

    摘要翻译： 递送药物的系统和方法。 称为CYC载体的结晶聚合体系通过化学键合或通过物理缔合与药物相关联。 CYC载体的结晶度来自可结晶侧链的存在，例如长链正烷基部分，这导致相对低的和尖锐的熔融温度。 称为CYSC聚合物的一类CYC载体具有从聚合物主链悬挂的大部分可结晶侧链。 称为ECC聚合物的另一类CYC载体具有连接至聚合物主链末端单元的大部分可结晶侧链。 ECC聚合物可以例如通过改性PLGA聚合物获得。 另一类的CYC载体是非聚合物。 一些称为CYC组件的CYC载体由于存在于不同类型分子中的可结晶部分的物理结合而具有增强的结晶度，例如在含可结晶部分的聚合物和含可结晶部分的单体之间。 CYC载体优选是可生物侵蚀的。

    SYSTEMS AND METHODS FOR DELIVERY OF MATERIALS
    8.
    发明申请
    SYSTEMS AND METHODS FOR DELIVERY OF MATERIALS 有权
    用于输送材料的系统和方法

    公开(公告)号：US20110009571A1

    公开(公告)日：2011-01-13

    申请号：US12746178

    申请日：2008-12-03

    申请人： David Taft ,  Steven Bitler ,  Qiang Zheng ,  Stelios Tzannis ,  Adam Bell ,  Wei-Guo Dai ,  Sandra N. Ottensmann ,  Natarajan Balachander

    发明人： David Taft ,  Steven Bitler ,  Qiang Zheng ,  Stelios Tzannis ,  Adam Bell ,  Wei-Guo Dai ,  Sandra N. Ottensmann ,  Natarajan Balachander

    IPC分类号： C08G63/06

    CPC分类号： A61K9/0024 ,  A61K9/0019 ,  A61K9/146

    摘要： Systems and methods for delivering release materials, for example drugs and other bioactive materials. Crystalline polymeric systems, referred to as CYC carriers, are associated with the release materials, through chemical bonding or through physical association. The crystallinity of the CYC carriers results from the presence of crystallizable side chains, for example long chain n-alkyl moieties, which results in relatively low and sharp melting temperatures. One class of CYC carriers, referred to as CYSC polymers, have a majority of the crystallizable side chains pendant from the polymer backbone. Another class of CYC carriers referred to as ECC polymers, have a majority of the crystallizable side chains attached to terminal units of the polymer backbone. The ECC polymers can for example be obtained by modification of PLGA polymers. The CYC carriers in another class of non-polymeric. Some CYC carriers, referred to as CYC assemblies, have enhanced crystallinity as a result of the physical association of crystallizable moieties which are present in different types of molecule, for example between a polymer containing crystallizable moieties and a monomer containing crystallizable moieties. For some uses, particularly the delivery of drugs, a bioerodable CYC carrier is preferably used.

    摘要翻译： 用于输送释放材料的系统和方法，例如药物和其他生物活性材料。 称为CYC载体的结晶聚合物体系通过化学键合或通过物理缔合与释放材料相关联。 CYC载体的结晶度来自可结晶侧链的存在，例如长链正烷基部分，这导致相对低的和尖锐的熔融温度。 称为CYSC聚合物的一类CYC载体具有从聚合物主链悬挂的大部分可结晶侧链。 称为ECC聚合物的另一类CYC载体具有连接至聚合物主链末端单元的大部分可结晶侧链。 ECC聚合物可以例如通过改性PLGA聚合物获得。 CYC载体在另一类非聚合物中。 一些称为CYC组件的CYC载体由于存在于不同类型分子中的可结晶部分的物理结合而具有增强的结晶度，例如在含可结晶部分的聚合物和含可结晶部分的单体之间。 对于一些用途，特别是药物的递送，优选使用生物侵蚀性CYC载体。