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公开(公告)号：US07226928B2
公开(公告)日：2007-06-05
申请号：US10479109
申请日：2002-06-14
IPC分类号： A61K31/535 , A61K31/44
CPC分类号： A61K9/0063 , A61K9/006 , A61K31/00 , A61K31/4745 , A61K45/06 , A61K2300/00
摘要： The disclosure provides methods for the treatment and prevention of periodontal disease. In preferred embodiments, the invention provides for local treatment of periodontal tissues with a pharmaceutical composition including an immune response modifier (IRM) selected from the group of immune response modifiers comprising imidazoquinoline amines, imidazopyridine amines, 6,7-fused cycloalkylimidazopyridine amines, imidazonaphtyridine amines, oxazoloquinoline amines, thiazoloquinoline amines and 1,2-bridged imidazopyridine amines.
摘要翻译： 本公开提供了治疗和预防牙周病的方法。 在优选实施方案中，本发明提供了用包含免疫应答调节剂（IRM）的药物组合物局部治疗牙周组织，所述免疫应答调节剂选自包含咪唑并喹啉胺，咪唑并吡啶胺，6,7-稠合的环烷基咪唑并吡啶胺，咪唑并吡啶胺 ，恶唑啉喹啉胺，噻唑并喹啉胺和1,2-桥连的咪唑并吡啶胺。
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公开(公告)号：US06596403B2
公开(公告)日：2003-07-22
申请号：US09977187
申请日：2001-10-12
IPC分类号： B32B2738
CPC分类号： A61K8/895 , A61Q11/00 , Y10T428/31612 , Y10T428/31663 , A61K6/0017 , C08L51/085
摘要： Coatings for hard tissue and surfaces of the oral environment are provided that reduce adhesion of bacteria and proteinaceous substances to these surfaces. Methods of reducing adhesion of these materials to such surfaces, and polymers for incorporation into such coatings are also provided.
摘要翻译： 提供用于硬组织和口腔环境表面的涂层，其减少细菌和蛋白质物质对这些表面的粘附。 还提供了将这些材料粘附到这些表面上的方法以及用于掺入这种涂层的聚合物。
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公开(公告)号：US5607663A
公开(公告)日：1997-03-04
申请号：US348048
申请日：1994-12-01
CPC分类号： A61K6/0017
摘要： Coatings for hard tissue and surfaces of the oral environment are provided that reduce adhesion of bacteria and proteinaceous substances to these surfaces. Methods of reducing adhesion of these materials to such surfaces, and polymers for incorporation into such coatings are also provided.
摘要翻译： 提供用于硬组织和口腔环境表面的涂层，其减少细菌和蛋白质物质对这些表面的粘附。 还提供了将这些材料粘附到这些表面上的方法以及用于掺入这种涂层的聚合物。
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公开(公告)号：US5888491A
公开(公告)日：1999-03-30
申请号：US347861
申请日：1994-12-01
IPC分类号： A61K9/70 , A61K6/02 , A61K6/083 , A61K6/093 , A61K8/00 , A61K8/34 , A61K8/35 , A61K8/36 , A61K8/368 , A61K8/37 , A61K8/46 , A61K8/49 , A61K8/58 , A61K8/89 , A61K8/891 , A61K8/892 , A61K8/895 , A61K8/91 , A61L27/34 , A61Q11/00 , C08L83/08 , A61K31/74
CPC分类号： A61K8/895 , A61K6/0017 , A61Q11/00
摘要： Coatings for hard tissue and surfaces of the oral environment are provided that reduce adhesion of bacteria and proteinaceous substances to these surfaces. Methods of reducing adhesion of these materials to such surfaces, and polymers for incorporation into such coatings are also provided.
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公开(公告)号：US06312668B2
公开(公告)日：2001-11-06
申请号：US09237870
申请日：1999-01-27
IPC分类号： A61K716
CPC分类号： A61K8/895 , A61Q11/00 , Y10T428/31612 , Y10T428/31663 , A61K6/0017 , C08L51/085
摘要： Coatings for hard tissue and surfaces of the oral environment are provided that reduce adhesion of bacteria and proteinaceous substances to these surfaces. Methods of reducing adhesion of these materials to such surfaces, and polymers for incorporation into such coatings are also provided.
摘要翻译： 提供用于硬组织和口腔环境表面的涂层，其减少细菌和蛋白质物质对这些表面的粘附。 还提供了将这些材料粘附到这些表面上的方法以及用于掺入这种涂层的聚合物。
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公开(公告)号：US5866630A
公开(公告)日：1999-02-02
申请号：US472000
申请日：1995-06-06
IPC分类号： A61K9/70 , A61K6/02 , A61K6/083 , A61K6/093 , A61K8/00 , A61K8/34 , A61K8/35 , A61K8/36 , A61K8/368 , A61K8/37 , A61K8/46 , A61K8/49 , A61K8/58 , A61K8/89 , A61K8/891 , A61K8/892 , A61K8/895 , A61K8/91 , A61L27/34 , A61Q11/00 , C08L83/08 , A61K6/00 , C08F30/08
CPC分类号： A61K8/895 , A61K6/0017 , A61Q11/00
摘要： Coatings for hard tissue and surfaces of the oral environment are provided that reduce adhesion of bacteria and proteinaceous substances to these surfaces. Methods of reducing adhesion of these materials to such surfaces, and polymers for incorporation into such coatings are also provided.
摘要翻译： 提供用于硬组织和口腔环境表面的涂层，其减少细菌和蛋白质物质对这些表面的粘附。 还提供了将这些材料粘附到这些表面上的方法以及用于掺入这种涂层的聚合物。
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公开(公告)号：US5662887A
公开(公告)日：1997-09-02
申请号：US347717
申请日：1994-12-01
CPC分类号： A23G4/06 , A61K6/0017 , A61K6/0029 , A61K6/0205 , A61K6/05 , A61K6/083 , A61K6/0835 , A61K8/8152 , A61Q11/00
摘要： Coatings for hard tissue and surfaces of the oral environment are provided that reduce adhesion of bacteria and proteinaceous substances to these surfaces. Methods of reducing adhesion of these materials to such surfaces, and polymers for incorporation into such coatings are also provided.
摘要翻译： 提供用于硬组织和口腔环境表面的涂层，其减少细菌和蛋白质物质对这些表面的粘附。 还提供了将这些材料粘附到这些表面上的方法以及用于掺入这种涂层的聚合物。
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公开(公告)号：US10137061B2
公开(公告)日：2018-11-27
申请号：US11719469
申请日：2005-11-07
摘要： The present application provides dental fillers, and methods of making and using dental fillers that include a treated surface that includes a phosphate salt. Dental compositions including such dental fillers can be useful for delivering ions to the oral environment. Dental compositions, and methods of using dental compositions that include a phosphate salt and a hardenable resin or a water-dispersible, polymeric film former are also provided.
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公开(公告)号：US08979536B2
公开(公告)日：2015-03-17
申请号：US13121956
申请日：2009-11-17
申请人： Todd D. Jones , Sumita B. Mitra , Gerald S. Deeb , Yufeng Liu , Jie Yang , Naimul Karim , Dwight W. Jacobs
发明人： Todd D. Jones , Sumita B. Mitra , Gerald S. Deeb , Yufeng Liu , Jie Yang , Naimul Karim , Dwight W. Jacobs
IPC分类号： A61C5/08 , A61C13/087 , A61C5/00 , A61C5/10 , A61C13/08 , A61C13/20 , A61C13/107
CPC分类号： A61C13/087 , A61C5/00 , A61C5/73 , A61C5/77 , A61C13/0001 , A61C13/081 , A61C13/20 , A61C2201/00 , A61C2202/00
摘要： A hardenable dental article including a base and at least one outer surface extending from the base, wherein at least the base and the at least one outer surface of the hardenable dental article includes a hardenable dental material; and a multi-layer polymeric film conformable release liner in contact with at least a portion of the at least one outer surface.
摘要翻译： 一种可硬化牙科制品，其包括基部和从所述基部延伸的至少一个外表面，其中至少所述可硬化牙科制品的所述基底和所述至少一个外表面包括可硬化的牙科材料; 以及与所述至少一个外表面的至少一部分接触的多层聚合物膜贴合隔离衬垫。
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公开(公告)号：US08900556B2
公开(公告)日：2014-12-02
申请号：US11745212
申请日：2007-05-07
申请人： Joel D. Oxman , Mai T. Nguyen , Sumita B. Mitra , Hoa T. Bui , Jingwen Ma , Jie J. Liu , Mahfuza B. Ali
发明人： Joel D. Oxman , Mai T. Nguyen , Sumita B. Mitra , Hoa T. Bui , Jingwen Ma , Jie J. Liu , Mahfuza B. Ali
IPC分类号： A61K6/00 , A61K6/083 , A61K31/765 , A61K6/087
CPC分类号： A61K6/083 , A61K6/0835 , A61K6/087 , A61K31/765 , C08L33/00 , C08L59/00
摘要： Thermally responsive compositions that include a thermally responsive viscosity modifier, a polymerizable component, and water are provided. The compositions, which optionally may be hardened, are useful for application to a surface of a body.
摘要翻译： 提供了包括热敏粘度调节剂，可聚合组分和水的热响应组合物。 任选地可以硬化的组合物可用于施用于身体的表面。
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