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公开(公告)号:US20080153770A1
公开(公告)日:2008-06-26
申请号:US11870361
申请日:2007-10-10
申请人: Sunyoung KIM , Sujeong KIM , Jun-Tae LEE
发明人: Sunyoung KIM , Sujeong KIM , Jun-Tae LEE
CPC分类号: C12N15/86 , C12N2740/13043 , C12N2830/00
摘要: The present invention relates to the use of internal promoters in mammalian expression vectors including plasmid vectors and enhancer-deleted retroviral vectors. The retroviral vectors have improved safety and optimal levels of transgene expression and vector titers.
摘要翻译: 本发明涉及内源启动子在哺乳动物表达载体中的应用,包括质粒载体和增强子缺失的逆转录病毒载体。 逆转录病毒载体改善了转基因表达和载体滴度的安全性和最佳水平。
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公开(公告)号:US20100285526A1
公开(公告)日:2010-11-11
申请号:US12431687
申请日:2009-04-28
申请人: Sujeong KIM , Jong-Mook Kim , Song Shan Xu
发明人: Sujeong KIM , Jong-Mook Kim , Song Shan Xu
IPC分类号: C12P21/06 , C12P1/00 , C07H21/04 , C12N15/63 , C12N5/10 , C07K14/00 , C07K14/52 , C07K16/00 , C07K14/54 , C07K14/545 , C07K14/55 , C07K14/555 , C07K14/56 , C07K14/565 , C07K14/57 , C07K14/475 , C07K14/525 , C07K14/53 , C12N9/96
CPC分类号: C12N15/62 , C07K7/06 , C07K7/08 , C07K14/5412 , C07K14/5431 , C07K14/57581 , C07K14/705 , C07K2319/00 , C07K2319/01
摘要: The present invention relates to compositions and methods for fusion protein separation utilizing a peptide linker comprising a novel thrombin cleavage site.
摘要翻译: 本发明涉及使用包含新型凝血酶切割位点的肽接头的融合蛋白分离的组合物和方法。
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