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公开(公告)号：US10029122B2
公开(公告)日：2018-07-24
申请号：US15176025
申请日：2016-06-07
摘要： The invention comprises a system for controlling a charged particle beam shape and direction relative to a controlled and dynamically positioned patient and/or an imaging surface, such as a scintillation plate of a tomography system and/or a first two-dimensional imaging system coupled to a second two-dimensional imaging system. Multiple interlinked beam/patient/imaging control stations allow safe zone operation and clear interaction with the charged particle beam system and the patient. Both treatment and imaging are facilitated using automated sequences controlled with a work-flow control system.
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2.发明申请CHARGED PARTICLE - PATIENT MOTION CONTROL SYSTEM APPARATUS AND METHOD OF USE THEREOF 审中-公开充电颗粒 - 患者运动控制系统装置及其使用方法公开(公告)号：US20160287907A1
公开(公告)日：2016-10-06
申请号：US15176025
申请日：2016-06-07
IPC分类号： A61N5/10
CPC分类号： A61N5/1049 , A61B6/032 , A61B6/4258 , A61B6/5205 , A61N5/1044 , A61N5/1067 , A61N5/107 , A61N5/1082 , A61N2005/105 , A61N2005/1054 , A61N2005/1087 , A61N2005/1095 , A61N2005/1097 , G21K1/08 , G21K5/04
摘要： The invention comprises a system for controlling a charged particle beam shape and direction relative to a controlled and dynamically positioned patient and/or an imaging surface, such as a scintillation plate of a tomography system and/or a first two-dimensional imaging system coupled to a second two-dimensional imaging system. Multiple interlinked beam/patient/imaging control stations allow safe zone operation and clear interaction with the charged particle beam system and the patient. Both treatment and imaging are facilitated using automated sequences controlled with a work-flow control system.
摘要翻译： 本发明包括一种用于控制带电粒子束形状和相对于被控和动态定位的患者和/或成像表面的方向的系统，诸如层析成像系统的闪烁板和/或第一二维成像系统 第二个二维成像系统。 多个相互连接的束/患者/成像控制站允许安全区域操作和与带电粒子束系统和患者的清晰的相互作用。 使用通过工作流控制系统控制的自动化序列便于治疗和成像。
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3.发明申请COUPLED TOMOGRAPHIC IMAGING SYSTEM AND CHARGED PARTICLE STATE DETERMINATION APPARATUS AND METHOD OF USE THEREOF 审中-公开联合图像成像系统和充电颗粒状态测定装置及其使用方法公开(公告)号：US20160279443A1
公开(公告)日：2016-09-29
申请号：US15174757
申请日：2016-06-06
IPC分类号： A61N5/10
CPC分类号： A61N5/1049 , A61B6/032 , A61N5/1039 , A61N5/1048 , A61N5/1067 , A61N5/107 , A61N5/1077 , A61N5/1081 , A61N5/1082 , A61N2005/1054 , A61N2005/1059 , A61N2005/1087 , A61N2005/1095 , A61N2005/1097 , G21K1/08 , G21K5/04
摘要： The invention comprises a system for using common injector, accelerator, beam transport, and/or imaging system elements for both imaging, such as tomographic imaging, and positively charged particle cancer therapy. For example, a common output nozzle of both a tomographic imaging system and the charged particle cancer therapy system is maintained on an opposite side of the patient from an imaging surface, such as a detection plate and/or a scintillation plate, where the imaging surface is used in tomographic imaging and/or during cancer treatment with the positively charged particles to confirm position and/or orientation of the tumor. Common beam state determination systems, such as charged particle position, direction, energy, and/or intensity determination systems are used to enhance both the imaging and cancer treatment system.
摘要翻译： 本发明包括一种用于使用共同的注射器，加速器，束输送和/或成像系统元件的系统，用于成像，例如断层摄影和带正电的粒子癌治疗。 例如，断层成像系统和带电粒子癌症治疗系统的共同输出喷嘴保持在与成像表面（例如检测板和/或闪烁板）相对的患者的相对侧，其中成像表面 用于断层成像和/或在带正电荷的颗粒的癌症治疗期间以确认肿瘤的位置和/或取向。 使用诸如带电粒子位置，方向，能量和/或强度确定系统的共同束状态确定系统来增强成像和癌症治疗系统。
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公开(公告)号：US10070831B2
公开(公告)日：2018-09-11
申请号：US15182507
申请日：2016-06-14
CPC分类号： A61B6/4085 , A61B6/032 , A61B6/4014 , A61B6/4258 , A61B6/487 , A61B6/5205 , A61N5/1044 , A61N5/1067 , A61N5/1069 , A61N5/107 , A61N5/1082 , A61N2005/105 , A61N2005/1054 , A61N2005/1061 , A61N2005/1087 , A61N2005/1095 , A61N2005/1097 , G21K1/08 , G21K5/04
摘要： The invention comprises a positively charged particle based cancer therapy system integrated with at least one off-axis imaging system, where elements of the off-axis imaging system and the cancer therapy system are co-positioned/co-rotated with a gantry. The imaging apparatus optionally functions with a tomography system using the positively charged particles of the cancer therapy system for enhanced patient/tumor imaging at and/or prior to a time of treatment.
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5.发明申请公开(公告)号：US20160287908A1
公开(公告)日：2016-10-06
申请号：US15182507
申请日：2016-06-14
CPC分类号： A61B6/4085 , A61B6/032 , A61B6/4014 , A61B6/4258 , A61B6/487 , A61B6/5205 , A61N5/1044 , A61N5/1067 , A61N5/1069 , A61N5/107 , A61N5/1082 , A61N2005/105 , A61N2005/1054 , A61N2005/1061 , A61N2005/1087 , A61N2005/1095 , A61N2005/1097 , G21K1/08 , G21K5/04
摘要： The invention comprises a positively charged particle based cancer therapy system integrated with at least one off-axis imaging system, where elements of the off-axis imaging system and the cancer therapy system are co-positioned/co-rotated with a gantry. The imaging apparatus optionally functions with a tomography system using the positively charged particles of the cancer therapy system for enhanced patient/tumor imaging at and/or prior to a time of treatment.
摘要翻译： 本发明包括与至少一个离轴成像系统集成的带正电粒子的癌症治疗系统，其中离轴成像系统的元件和癌症治疗系统与台架共同定位/共转动。 成像设备可选地与使用癌症治疗系统的带正电颗粒的断层摄影系统一起起作用，以在治疗时和/或之前进行增强的患者/肿瘤成像。
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公开(公告)号：US10307617B2
公开(公告)日：2019-06-04
申请号：US15860122
申请日：2018-01-02
摘要： The invention comprises a system for controlling a charged particle beam shape and direction relative to a controlled and dynamically positioned patient and/or an imaging surface, such as a scintillation plate of a tomography system and/or a first two-dimensional imaging system coupled to a second two-dimensional imaging system. Multiple interlinked beam/patient/imaging control stations allow safe zone operation and clear interaction with the charged particle beam system and the patient. Both treatment and imaging are facilitated using automated sequences controlled with a work-flow control system.
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公开(公告)号：US20180140870A1
公开(公告)日：2018-05-24
申请号：US15860122
申请日：2018-01-02
CPC分类号： A61N5/1049 , A61B6/032 , A61B6/4258 , A61B6/5205 , A61N5/1044 , A61N5/1067 , A61N5/107 , A61N5/1082 , A61N2005/105 , A61N2005/1054 , A61N2005/1087 , A61N2005/1095 , A61N2005/1097 , G21K1/08 , G21K5/04
摘要： The invention comprises a system for controlling a charged particle beam shape and direction relative to a controlled and dynamically positioned patient and/or an imaging surface, such as a scintillation plate of a tomography system and/or a first two-dimensional imaging system coupled to a second two-dimensional imaging system. Multiple interlinked beam/patient/imaging control stations allow safe zone operation and clear interaction with the charged particle beam system and the patient. Both treatment and imaging are facilitated using automated sequences controlled with a work-flow control system.
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8.发明申请公开(公告)号：US20160271424A1
公开(公告)日：2016-09-22
申请号：US15167617
申请日：2016-05-27
IPC分类号： A61N5/10
CPC分类号： A61N5/1069 , A61B6/032 , A61B6/4258 , A61B6/5205 , A61N5/1037 , A61N5/1044 , A61N5/1067 , A61N5/107 , A61N5/1077 , A61N5/1082 , A61N2005/105 , A61N2005/1054 , A61N2005/1087 , A61N2005/1095 , A61N2005/1097 , G21K1/08 , G21K5/04
摘要： The invention comprises a system for determining the state of a charged particle beam, such as beam position, intensity, and/or energy. For example, the charged particle beam state is determined at or about a patient undergoing charged particle cancer therapy using one or more film layers designed to emit photons upon passage of a charged particle beam, which yields information on position and/or intensity of the charged particle beam. The emitted photons are used to calculate position of the treatment beam in imaging and/or during tumor treatment. Optionally and preferably, updating a tomography map uses the same hardware with the same alignment used for cancer therapy at proximately the same time.
摘要翻译： 本发明包括用于确定带电粒子束的状态的系统，例如光束位置，强度和/或能量。 例如，带电粒子束状态是在使用一个或多个设计成在带电粒子束通过时发射光子的一个或多个膜层进行带电粒子癌治疗的患者或周围确定的，其产生关于带电粒子束的位置和/或强度的信息 粒子束。 发射的光子用于计算成像和/或肿瘤治疗期间治疗束的位置。 任选且优选地，更新断层摄影图使用与大致相同的时间使用与癌症治疗相同的比对的相同的硬件。
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公开(公告)号：US09737733B2
公开(公告)日：2017-08-22
申请号：US15167617
申请日：2016-05-27
CPC分类号： A61N5/1069 , A61B6/032 , A61B6/4258 , A61B6/5205 , A61N5/1037 , A61N5/1044 , A61N5/1067 , A61N5/107 , A61N5/1077 , A61N5/1082 , A61N2005/105 , A61N2005/1054 , A61N2005/1087 , A61N2005/1095 , A61N2005/1097 , G21K1/08 , G21K5/04
摘要： The invention comprises a system for determining the state of a charged particle beam, such as beam position, intensity, and/or energy. For example, the charged particle beam state is determined at or about a patient undergoing charged particle cancer therapy using one or more film layers designed to emit photons upon passage of a charged particle beam, which yields information on position and/or intensity of the charged particle beam. The emitted photons are used to calculate position of the treatment beam in imaging and/or during tumor treatment. Optionally and preferably, updating a tomography map uses the same hardware with the same alignment used for cancer therapy at proximately the same time.
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公开(公告)号：US09974978B2
公开(公告)日：2018-05-22
申请号：US15239773
申请日：2016-08-17
CPC分类号： A61N5/1069 , A61B6/03 , A61B6/032 , A61B6/0457 , A61B6/4014 , A61B6/4092 , A61B6/4258 , A61B6/4266 , A61B6/4417 , A61B6/4435 , A61B6/5205 , A61B6/5247 , A61N5/1037 , A61N5/1039 , A61N5/1067 , A61N5/107 , A61N5/1077 , A61N5/1082 , A61N2005/105 , A61N2005/1054 , A61N2005/1061 , A61N2005/1087 , A61N2005/1095 , A61N2005/1097 , G01N23/046 , G01N2223/107 , G01N2223/203 , G21K1/093 , G21K5/04
摘要： A scintillation material is longitudinally packaged in a circumferentially surrounding sheath, where the sheath has a lower index of refraction than the scintillation material, to form a scintillation optic or scintillation fiber optic. The scintillation material yields secondary photons upon passage of a charged particle beam, such as a positively charged residual particle beam having transmitted through a sample. The internally generated secondary photons within the sheath are guided to a detector element by the difference in index of refraction. Multiple scintillation optics are assembled to form a two-dimensional scintillation array coupled to a two-dimensional detector array, such as for use in determination of state of the residual charged particle beam, determination of an exit point of the particle beam from the sample, path of the treatment beam, and/or tomographic imaging.
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