-
公开(公告)号：US06400992B1
公开(公告)日：2002-06-04
申请号：US09271498
申请日：1999-03-18
申请人： Svenn E. Borgersen , Hans W. Kramer
发明人： Svenn E. Borgersen , Hans W. Kramer
IPC分类号： A61N105
摘要： Medical electrical leads for sensing or electrical stimulation of body organs or tissues, particularly implantable cardiac leads for delivering pacing pulses and cardioversion/defibrillation shocks, and/or sensing the cardiac electrogram (EGM) or other physiologic data and their methods of fabrication are disclosed. A lead body sheath is co-extruded in a co-extrusion process using bio-compatible, electrically insulating, materials of differing durometers in differing axial sections thereof, resulting in a unitary lead body sheath having differing stiffness sections including axial segments or webs or lumen encircling rings or other structures in its cross-section. The lead body sheath is co-extruded to have an outer surface adapted to be exposed to the environment or to be enclosed within an outer sheath and to have a plurality of lead conductor lumens for receiving and enclosing a like plurality of lead conductors of the same or differing types. The lead body sheath can be co-extruded of a plurality of sheath segments containing a lead conductor lumen and formed of a first durometer material or of differing durometer materials. A web of a further durometer material can be co-extruded extending between the adjoining boundaries of the axial sheath segments and bonding the adjacent segments together. The lead body sheath can be tailored to exhibit differing bending stiffnesses away from the lead body sheath axis in selected polar directions around 360° circumference of the sheath body.
摘要翻译： 公开了用于感测或电刺激身体器官或组织的医疗电引线，特别是用于输送起搏脉冲和心律转复/除颤电击的可植入心脏引线和/或感测心电图（EGM）或其他生理数据及其制造方法。 引线体护套在共挤出工艺中共挤出，使用生物相容的，电绝缘的不同硬度的不同的轴向部分的材料，导致整体引线体护套具有不同的刚度部分，其包括轴向段或腹板或内腔 围绕环或其他结构的横截面。 引线体护套被共挤出以具有适于暴露于环境的外表面或被包封在外护套内并且具有多个引线导体流体用于接收和封闭相同的多个引线导体 或不同类型。 引线体护套可以由包含引线导体腔并由第一硬度计材料或不同硬度材料形成的多个鞘段共同挤出。 可以在轴向鞘段的相邻边界之间共同挤出延伸的另一硬度材料的网，并将相邻的段结合在一起。 引线体护套可以被定制成在鞘本体的360°圆周周围的选定的极方向上表现出远离引线主体护套轴线的不同的弯曲刚度。
-
公开(公告)号：US06434430B1
公开(公告)日：2002-08-13
申请号：US09851850
申请日：2001-05-09
申请人： Svenn E. Borgersen , Hans W. Kramer
发明人： Svenn E. Borgersen , Hans W. Kramer
IPC分类号： A61N105
摘要： Medical electrical leads for sensing or electrical stimulation of body organs or tissues, particularly implantable cardiac leads for delivering pacing pulses and cardioversion/defibrillation shocks, and/or sensing the cardiac electrogram (EGM) or other physiologic data and their methods of fabrication are disclosed. A lead body sheath is co-extruded in a co-extrusion process using bio-compatible, electrically insulating, materials of differing durometers in differing axial sections thereof, resulting in a unitary lead body sheath having differing stiffness sections including axial segments or webs or lumen encircling rings or other structures in its cross-section. The lead body sheath is co-extruded to have an outer surface adapted to be exposed to the environment or to be enclosed within an outer sheath and to have a plurality of lead conductor lumens for receiving and enclosing a like plurality of lead conductors of the same or differing types. The lead body sheath can be co-extruded of a plurality of sheath segments containing a lead conductor lumen and formed of a first durometer material or of differing durometer materials. A web of a further durometer material can be co-extruded extending between the adjoining boundaries of the axial sheath segments and bonding the adjacent segments together. The lead body sheath can be tailored to exhibit differing bending stiffnesses away from the lead body sheath axis in selected polar directions around the 360° circumference of the sheath body.
-
3.发明申请Method and device for performing cooling-or cryo-therapies for, e.g., angioplasty with reduced restenosis or pulmonary vein cell necrosis to inhibit atrial fibrillation 有权用于进行冷冻或低温治疗的方法和装置，例如血管成形术，减少再狭窄或肺静脉细胞坏死以抑制心房颤动公开(公告)号：US20080300585A1
公开(公告)日：2008-12-04
申请号：US11978888
申请日：2007-10-30
IPC分类号： A61B18/02
CPC分类号： A61F7/12 , A61B18/02 , A61B2017/22002 , A61B2017/22054 , A61B2018/00023 , A61B2018/0022 , A61B2018/0212 , A61B2018/0262 , A61F2007/126
摘要： The present invention provides an enhanced method and device to inhibit or reduce the rate of restenosis following angioplasty or stent placement. The invention involves placing a balloon tipped catheter in the area treated or opened through balloon angioplasty immediately following angioplasty. The balloon, which can have a dual balloon structure, may be delivered through a guiding catheter and over a guidewire already in place from a balloon angioplasty. A fluid such as a perfluorocarbon may be flowed into the balloon to freeze the tissue adjacent the balloon, this cooling being associated with reduction of restenosis. The catheter may also be used to reduce atrial fibrillation by inserting and inflating the balloon such that an exterior surface of the balloon is in contact with at least a partial circumference of the portion of the pulmonary vein adjacent the left atrium.
摘要翻译： 本发明提供了抑制或降低血管成形术或支架放置后再狭窄发生率的增强方法和装置。 本发明涉及将气囊顶端的导管放置在血管成形术后立即通过球囊血管成形术处理或打开的区域中。 可以具有双气囊结构的气囊可以通过引导导管并且已经从球囊血管成形术已经就位的导线传送。 诸如全氟化碳的流体可以流入气囊中以冷冻邻近球囊的组织，这种冷却与再狭窄的减少有关。 导管还可用于通过插入和充气气囊来减少心房颤动，使得球囊的外表面与邻近左心房的肺静脉部分的至少部分圆周接触。
-
公开(公告)号：US06450987B1
公开(公告)日：2002-09-17
申请号：US09775708
申请日：2001-02-01
申请人： Hans W. Kramer
发明人： Hans W. Kramer
IPC分类号： A61M500
CPC分类号： A61M25/0023 , A61M2025/0025
摘要： A wire guided fluid catheter assembly having a collapsible guidewire lumen. Pressurization of a fluid lumen in the catheter assembly collapses the guidewire lumen, thereby increasing the fluid flow capacity of the catheter assembly.
摘要翻译： 具有可折叠导丝管腔的导线导管组件。 导管组件中的流体腔的加压使导丝管腔塌陷，从而增加导管组件的流体流动能力。
-
5.发明授权Method and device for performing cooling- or cryo-therapies for, e.g., angioplasty with reduced restenosis or pulmonary vein cell necrosis to inhibit atrial fibrillation employing tissue protection 有权用于进行冷冻或低温治疗的方法和装置，例如血管成形术，减少再狭窄或肺静脉细胞坏死，以抑制使用组织保护的心房颤动公开(公告)号：US07288089B2
公开(公告)日：2007-10-30
申请号：US11151488
申请日：2005-06-13
IPC分类号： A61B18/18
CPC分类号： A61F7/12 , A61B18/02 , A61B18/08 , A61B2017/00243 , A61B2017/22002 , A61B2017/22051 , A61B2017/22054 , A61B2018/00023 , A61B2018/00041 , A61B2018/0022 , A61B2018/0212 , A61B2018/0262 , A61F2007/126
摘要： An enhanced method and device are provided to treat atrial fibrillation or inhibit or reduce restenosis following angioplasty or stent placement. A balloon-tipped catheter is disposed in the area treated or opened through balloon angioplasty immediately following angioplasty. The balloon, which can have a dual balloon structure, may be delivered through a guiding catheter and over a guidewire already in place. A fluid such as a perfluorocarbon flows into the balloon to freeze the tissue adjacent the balloon, this cooling being associated with reduction of restenosis. A similar catheter may be used to reduce atrial fibrillation by inserting and inflating the balloon such that an exterior surface of the balloon contacts at least a partial circumference of the portion of the pulmonary vein adjacent the left atrium. In another embodiment, blood perfusion is performed simultaneously. In another embodiment, tissue contacted by the cryoablation catheter, undesired to be ablated, is protected against damage by a separate heating step.
摘要翻译： 提供增强的方法和装置以治疗房颤或抑制或减少血管成形术或支架置入后的再狭窄。 血管成形术后立即将球囊导管放置在通过球囊血管成形术处理或打开的区域中。 可以具有双气囊结构的气囊可以通过引导导管并且已经在已经就位的导丝上传送。 诸如全氟化碳的流体流入气球以冷冻邻近球囊的组织，这种冷却与再狭窄的减少有关。 类似的导管可用于通过插入和充气气囊来减少心房颤动，使得球囊的外表面接触邻近左心房的肺静脉部分的至少部分圆周。 在另一个实施方案中，同时进行血液灌注。 在另一个实施方案中，由冷冻消融导管接触的不希望消融的组织通过单独的加热步骤被保护而不被损坏。
-
公开(公告)号：US5871468A
公开(公告)日：1999-02-16
申请号：US829012
申请日：1997-03-31
申请人： Hans W. Kramer , Show-Mean Wu , Ziyun Chen , Mauricio L. Fugoso
发明人： Hans W. Kramer , Show-Mean Wu , Ziyun Chen , Mauricio L. Fugoso
CPC分类号： A61M25/1027 , A61M25/10
摘要： A balloon for use in a catheter, wherein the balloon is formed from an aromatic polyester, preferably a blend of a major component comprising an aromatic polyester, and a minor component comprising a compatible secondary thermoplastic semicrystalline polymer having a crystallinity less than that of the aromatic polyester of the major component.
摘要翻译： 一种用于导管的球囊，其中所述球囊由芳族聚酯形成，优选由包含芳族聚酯的主要组分的共混物和包含具有小于所述芳族化合物的结晶度的相容的次级热塑性半结晶聚合物的次要组分 聚酯的主要成分。
-
7.发明授权Method and device for performing cooling-or cryo-therapies for, e.g., angioplasty with reduced restenosis or pulmonary vein cell necrosis to inhibit atrial fibrillation 有权用于进行冷冻或低温治疗的方法和装置，例如血管成形术，减少再狭窄或肺静脉细胞坏死以抑制心房颤动公开(公告)号：US08157794B2
公开(公告)日：2012-04-17
申请号：US11978888
申请日：2007-10-30
IPC分类号： A61B18/02
CPC分类号： A61F7/12 , A61B18/02 , A61B2017/22002 , A61B2017/22054 , A61B2018/00023 , A61B2018/0022 , A61B2018/0212 , A61B2018/0262 , A61F2007/126
摘要： The present invention provides an enhanced method and device to inhibit or reduce the rate of restenosis following angioplasty or stent placement. The invention involves placing a balloon tipped catheter in the area treated or opened through balloon angioplasty immediately following angioplasty. The balloon, which can have a dual balloon structure, may be delivered through a guiding catheter and over a guidewire already in place from a balloon angioplasty. A fluid such as a perfluorocarbon may be flowed into the balloon to freeze the tissue adjacent the balloon, this cooling being associated with reduction of restenosis. The catheter may also be used to reduce atrial fibrillation by inserting and inflating the balloon such that an exterior surface of the balloon is in contact with at least a partial circumference of the portion of the pulmonary vein adjacent the left atrium.
摘要翻译： 本发明提供了抑制或降低血管成形术或支架放置后再狭窄发生率的增强方法和装置。 本发明涉及将气囊顶端的导管放置在血管成形术后立即通过球囊血管成形术处理或打开的区域中。 可以具有双气囊结构的气囊可以通过引导导管并且已经从球囊血管成形术已经就位的导线传送。 诸如全氟化碳的流体可以流入气囊中以冷冻邻近球囊的组织，这种冷却与再狭窄的减少有关。 导管还可用于通过插入和充气气囊来减少心房颤动，使得球囊的外表面与邻近左心房的肺静脉部分的至少部分圆周接触。
-
8.发明授权METHOD AND DEVICE FOR PERFORMING COOLING- OR CRYO-THERAPIES FOR, E.G., ANGIOPLASTY WITH REDUCED RESTENOSIS OR PULMONARY VEIN CELL NECROSIS TO INHIBIT ATRIAL FIBRILLATION EMPLOYING MICROPOROUS BALLOON 有权用于对E.G.，具有减少的抑制或肺动脉细胞损伤的放射治疗的冷冻或CRYO治疗方法和装置，以禁止使用微波炉的ATRIAL FIBRILLATION公开(公告)号：US06685732B2
公开(公告)日：2004-02-03
申请号：US09932402
申请日：2001-08-17
申请人： Hans W. Kramer
发明人： Hans W. Kramer
IPC分类号： A61F700
CPC分类号： A61F7/12 , A61B18/02 , A61B18/08 , A61B2017/22002 , A61B2017/22051 , A61B2017/22054 , A61B2018/00023 , A61B2018/00041 , A61B2018/0022 , A61B2018/0212 , A61B2018/0262 , A61F2007/126
摘要： An enhanced method and device are provided to inhibit or reduce restenosis following angioplasty or stent placement. A porous balloon-tipped catheter is disposed in the area treated or opened through balloon angioplasty immediately following angioplasty. The balloon, which can have a dual balloon structure, may be delivered through a guiding catheter and over a guidewire already in place. A fluid such as a perfluorocarbon flows into the balloon to freeze the tissue adjacent the balloon, this cooling being associated with reduction of restenosis. A similar catheter may be used to reduce atrial fibrillation by inserting and inflating the porous balloon such that an exterior surface of the balloon, as well as a portion of the cold working fluid, from the microporosity contacts at least a partial circumference of the portion of the pulmonary vein adjacent the left atrium.
摘要翻译： 提供增强的方法和装置，用于抑制或减少血管成形术或支架置入后的再狭窄。 在血管成形术后立即通过气囊血管成形术将多孔气球导管置于经处理或打开的区域中。 可以具有双气囊结构的气囊可以通过引导导管并且已经在已经就位的导丝上传送。 诸如全氟化碳的流体流入气球以冷冻邻近球囊的组织，这种冷却与再狭窄的减少有关。 类似的导管可以用于通过插入和充气多孔气囊来减少心房颤动，使得球囊的外表面以及一部分冷加工流体从微孔接触至少部分的部分圆周 肺静脉邻近左心房。
-
9.发明授权Method and device for performing cooling- or cryo-therapies for, e.g., angioplasty with reduced restenosis or pulmonary vein cell necrosis to inhibit atrial fibrillation 有权用于进行冷冻或低温治疗的方法和装置，例如血管成形术，减少再狭窄或肺静脉细胞坏死以抑制心房颤动公开(公告)号：US08043283B2
公开(公告)日：2011-10-25
申请号：US11982988
申请日：2007-11-06
IPC分类号： A61B18/02
CPC分类号： A61F7/12 , A61B18/02 , A61B2017/22002 , A61B2017/22054 , A61B2018/00023 , A61B2018/0022 , A61B2018/0212 , A61B2018/0262 , A61F2007/126
摘要： The present invention provides an enhanced method and device to inhibit or reduce the rate of restenosis following angioplasty or stent placement. The invention involves placing a balloon tipped catheter in the area treated or opened through balloon angioplasty immediately following angioplasty. The balloon, which can have a dual balloon structure, may be delivered through a guiding catheter and over a guidewire already in place from a balloon angioplasty. A fluid such as a perfluorocarbon may be flowed into the balloon to freeze the tissue adjacent the balloon, this cooling being associated with reduction of restenosis. The catheter may also be used to reduce atrial fibrillation by inserting and inflating the balloon such that an exterior surface of the balloon is in contact with at least a partial circumference of the portion of the pulmonary vein adjacent the left atrium.
摘要翻译： 本发明提供了抑制或降低血管成形术或支架放置后再狭窄发生率的增强方法和装置。 本发明涉及将气囊顶端的导管放置在血管成形术后立即通过球囊血管成形术处理或打开的区域中。 可以具有双气囊结构的气囊可以通过引导导管并且已经从球囊血管成形术已经就位的导线传送。 诸如全氟化碳的流体可以流入气囊中以冷冻邻近球囊的组织，这种冷却与再狭窄的减少有关。 导管还可用于通过插入和充气气囊来减少心房颤动，使得球囊的外表面与邻近左心房的肺静脉部分的至少部分圆周接触。
-
10.发明授权Method and device for performing cooling- or cryo-therapies for, e.g., angioplasty with reduced restenosis or pulmonary vein cell necrosis to inhibit atrial fibrillation 有权用于进行冷冻或低温治疗的方法和装置，例如血管成形术，减少再狭窄或肺静脉细胞坏死以抑制心房颤动公开(公告)号：US07291144B2
公开(公告)日：2007-11-06
申请号：US10039466
申请日：2002-01-03
IPC分类号： A61B18/02
CPC分类号： A61F7/12 , A61B18/02 , A61B2017/22002 , A61B2017/22054 , A61B2018/00023 , A61B2018/0022 , A61B2018/0212 , A61B2018/0262 , A61F2007/126
摘要： The present invention provides an enhanced method and device to inhibit or reduce the rate of restenosis following angioplasty or stent placement. The invention involves placing a balloon tipped catheter in the area treated or opened through balloon angioplasty immediately following angioplasty. The balloon, which can have a dual balloon structure, may be delivered through a guiding catheter and over a guidewire already in place from a balloon angioplasty. A fluid such as a perfluorocarbon may be flowed into the balloon to freeze the tissue adjacent the balloon, this cooling being associated with reduction of restenosis. The catheter may also be used to reduce atrial fibrillation by inserting and inflating the balloon such that an exterior surface of the balloon is in contact with at least a partial circumference of the portion of the pulmonary vein adjacent the left atrium.
摘要翻译： 本发明提供了抑制或降低血管成形术或支架放置后再狭窄发生率的增强方法和装置。 本发明涉及将气囊顶端的导管放置在血管成形术后立即通过球囊血管成形术处理或打开的区域中。 可以具有双气囊结构的气囊可以通过引导导管并且已经从球囊血管成形术已经就位的导线传送。 诸如全氟化碳的流体可以流入气囊中以冷冻邻近球囊的组织，这种冷却与再狭窄的减少有关。 导管还可用于通过插入和充气气囊来减少心房颤动，使得球囊的外表面与邻近左心房的肺静脉部分的至少部分圆周接触。
-
-
-
-
-
-
-
-
-
搜索结果
16 条记录 (耗时 0.022 秒)
