摘要:
A fragment of lysozyme which contains a minimum nine amino acid sequence with antiviral, anti-tumor and bactericidal activities but lacking muramidase activity is provided. The invention also relates to pharmaceutical compositions containing this fragment and methods for treating HIV infection or for inhibiting tumor growth using this fragment as an active ingredient.
摘要:
Methods described herein relate to mitochondria and their role in Human immunodeficiency virus type 1 (HIV-1) infection and cell-to-cell HIV-1 transmission and compositions and methods for modulating mitochondrial mediated cell-to-cell transmission of HIV-1. Methods for screening to identify inhibitors of mitochondrial mediated cell-to-cell transmission of HIV-1 are also envisioned herein.
摘要:
Methods described herein relate to mitochondria and their role in Human immunodeficiency virus type 1 (HIV-1) infection and cell-to-cell HIV-1 transmission and compositions and methods for modulating mitochondrial mediated cell-to-cell transmission of HIV-1. Methods for screening to identify inhibitors of mitochondrial mediated cell-to-cell transmission of HIV-1 are also envisioned herein.
摘要:
A fragment of lysozyme which contains a minimum nine amino acid sequence with antiviral, anti-tumor and bactericidal activities but lacking muramidase activity is provided. The invention also relates to pharmaceutical compositions containing this fragment and methods for treating HIV infection or for inhibiting tumor growth using this fragment as an active ingredient.
摘要:
A scheme for arbitrating access to a data bus shared among a plurality of competing sources is provided. Each competing source is assigned an adjustable priority weighting value (PWV) which is initially set to an initial value based on the bandwidth requirements of the competing source. During arbitration, the PWVs of those competing sources requesting access to the bus are compared, and the competing source with the smallest PWV is granted access. The PWV of the competing source which was granted access to the bus is reset to its initial value and the PWV of each competing source which requested, but was denied, access is reduced by one for subsequent comparisons. The arbitration scheme of the present invention is further applied to two-level arbitration. Each competing source is classified into a competing source group, and the requests from the grouped competing sources are processed by first level arbitration. First level arbitration passes one competing source for each group to a second level arbiter. The second level arbiter compares the PWVs of the competing sources resulting from first level arbitration to determine the competing source with the smallest PWV, and adjusts the PWVs after access to the bus has been granted.
摘要:
A disposable liner assembly to be placed in a pan for the successive sifting of litter and removal of animal waste, each sheet is arranged above and below one another such that the sifting apertures in the sheet are above and below the solid portions of a sheet below and above it to form an apertures closure. Some embodiments are provided with positioning apertures in each sheet make it easy to properly offset the thin flexible sheets relative to one another. The present invention also includes a shielded liner retainer to be removably placed over the pan to cover and clamp the liners in a fix position.
摘要:
A method for capturing stem cells and/or progenitor cells from circulating body fluids such as blood or lymph in vivo and enabling the cells to colonize a specific, localized site for purposes of tissue regeneration or repair, has been developed. The method consists of selecting a site in need of repair or regeneration. Materials which can be used to provide the growth factors or ligands include polymeric matrices having the growth factor or ligands attached thereto, materials releasing growth factor or ligands (such as hydrogels, polymers, fibrin clots), and cells which release or have bound to their surfaces the growth factors or ligands.
摘要:
A motorcycle mileage counter inductor is constructed to include a magnetic device holder mounted in the outer end of the tubular color of the wheel set of a motorcycle's front wheel, an annular magnetic device mounted on the magnetic device holder, the annular magnetic device having a plurality of magnets alternatively abutted against one another in reversed directions, and a sensor formed of a Hall chip and mounted in a cover shell being affixed to the front fork of the motorcycle around the outer end of the tubular collar and electrically connected to the mileage counter and ABS (anti-locking brake system) of the motorcycle through a signal line for detecting the amount of rotation of the motorcycle's front wheel and providing a signal indicative of the amount of rotation of the motorcycle's front wheel to the mileage counter and ABS of the motorcycle.
摘要:
An implantable magnetic relaxation sensor is provided that comprises superparamagnetic nanoparticies functionalized with one or more agents that bond with a biomarker of interest. The sensor is configured for minimally-invasive implantation into a human or animal, and is configured to indicate the implanted sensor's cumulative exposure to the biomarker of interest by analysis using magnetic resonance relaxometry.
摘要:
A motorcycle stand control mechanism is constructed to include a rotor rotatable with the transmission line of the cable of the mileage meter of the motorcycle in which the motorcycle stand control mechanism is installed, a rotary driven member fixedly fastened to one end of the rotor, the rotary driven member having a plurality of magnets alternatively arranged around the periphery thereof in reversed direction, and a fixedly circuit board provided near one side of the rotary driven member, the circuit board having sensor adapted to act with the magnets and to output a corresponding control signal to turn the motorcycle stand of the motorcycle subject to the status of the rotary driven member.