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公开(公告)号：US10792353B2
公开(公告)日：2020-10-06
申请号：US16213297
申请日：2018-12-07
发明人： Thomas S. Vedvick , Bryan Steadman , Charles Richardson , Thomas R. Foubert , Charles R. Petrie
IPC分类号： A61K39/12 , C12N7/00 , C07K1/18 , C07K14/005
摘要： Methods for purifying human Calciviruses are disclosed, including Noroviruses and Sapoviruses.
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公开(公告)号：US10512682B2
公开(公告)日：2019-12-24
申请号：US15994887
申请日：2018-05-31
摘要： The present invention relates to antigenic and vaccine compositions comprising Norovirus antigens and adjuvants, in particular, mixtures of monovalent VLPs and mixtures of multivalent VLPs, and to a process for the production of both monovalent and multivalent VLPs, the VLPs comprising capsid proteins from one or more Norovirus genogroups.
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公开(公告)号：US10172930B2
公开(公告)日：2019-01-08
申请号：US15144265
申请日：2016-05-02
发明人： Thomas S. Vedvick , Bryan Steadman , Charles Richardson , Thomas R. Foubert , Charles R. Petrie
IPC分类号： A61K39/125 , A61K39/12 , C12N7/00 , C07K1/18 , C07K14/005
摘要： Methods for purifying human Calciviruses are disclosed, including Noroviruses and Sapoviruses.
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公开(公告)号：US11040097B2
公开(公告)日：2021-06-22
申请号：US16870020
申请日：2020-05-08
IPC分类号： A61K39/12 , A61K39/125 , A61K39/00 , C12N7/00 , A61K39/39
摘要： The present invention relates to vaccine compositions comprising Norovirus antigens and adjuvants, in particular, mixtures of monovalent VLPs and mixtures of multivalent VLPs, and to methods of conferring protective immunity to Norovirus infections in a human subject.
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公开(公告)号：US20190381164A1
公开(公告)日：2019-12-19
申请号：US16429580
申请日：2019-06-03
摘要： The present invention relates to vaccine compositions comprising Norovirus antigens and adjuvants, in particular, mixtures of monovalent VLPs and mixtures of multivalent VLPs, and to methods of conferring protective immunity to Norovirus infections in a human subject.
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公开(公告)号：US09821049B2
公开(公告)日：2017-11-21
申请号：US13837389
申请日：2013-03-15
IPC分类号： A61K39/125 , A61K39/12 , A61K39/00
CPC分类号： A61K39/12 , A61K39/125 , A61K2039/5258 , A61K2039/543 , A61K2039/55572 , A61K2039/57 , C12N2770/16034
摘要： The present invention relates to vaccine compositions comprising Norovirus antigens and adjuvants, in particular, mixtures of monovalent VLPs and mixtures of multivalent VLPs, and to methods of conferring protective immunity to Norovirus infections in a human subject.
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公开(公告)号：US09272028B2
公开(公告)日：2016-03-01
申请号：US13837885
申请日：2013-03-15
IPC分类号： A61K39/125 , A61K39/12 , C07K16/10 , A61K39/00
CPC分类号： A61K39/12 , A61K39/125 , A61K39/39 , A61K2039/5258 , A61K2039/54 , A61K2039/543 , A61K2039/55572 , A61K2039/70 , C07K16/10 , C12N7/00 , C12N2770/16023 , C12N2770/16034
摘要： The present invention relates to antigenic and vaccine compositions comprising Norovirus antigens and adjuvants, in particular, mixtures of monovalent VLPs and mixtures of multivalent VLPs, and to a process for the production of both monovalent and multivalent VLPs, the VLPs comprising capsid proteins from one or more Norovirus genogroups.
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公开(公告)号：US09359410B2
公开(公告)日：2016-06-07
申请号：US13914331
申请日：2013-06-10
发明人： Thomas S. Vedvick , Bryan Steadman , Charles Richardson , Thomas R. Foubert , Charles R. Petrie
IPC分类号： C07K1/18 , C07K14/005 , C12N7/00
CPC分类号： A61K39/12 , C07K1/18 , C07K14/005 , C12N7/00 , C12N2770/16023 , C12N2770/16034 , C12N2770/16051
摘要： Methods for purifying human Calciviruses are disclosed, including Noroviruses and Sapoviruses.
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公开(公告)号：US10688174B2
公开(公告)日：2020-06-23
申请号：US16429580
申请日：2019-06-03
IPC分类号： A61K39/12 , A61K39/00 , A61K39/125 , C12N7/00 , A61K39/39
摘要： The present invention relates to vaccine compositions comprising Norovirus antigens and adjuvants, in particular, mixtures of monovalent VLPs and mixtures of multivalent VLPs, and to methods of conferring protective immunity to Norovirus infections in a human subject.
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公开(公告)号：US20190282686A1
公开(公告)日：2019-09-19
申请号：US16213297
申请日：2018-12-07
发明人： Thomas S. Vedvick , Bryan Steadman , Charles Richardson , Thomas R. Foubert , Charles R. Petrie
IPC分类号： A61K39/12 , C07K1/18 , C12N7/00 , C07K14/005
摘要： Methods for purifying human Calciviruses are disclosed, including Noroviruses and Sapoviruses.
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