公开(公告)号：US20180074013A1

公开(公告)日：2018-03-15

申请号：US15818428

申请日：2017-11-20

Applicant: TECAN TRADING AG

Inventor： TRAVIS LEE ,  Michael Benjamin Franklin ,  Kailiang Wang ,  Anne R. Kopf-Sill

IPC: G01N27/447

CPC classification number: G01N27/44791 ,  B01L3/502715 ,  B01L3/502738 ,  B01L3/502792 ,  B01L3/5029 ,  B01L3/523 ,  B01L3/527 ,  B01L7/52 ,  B01L2200/025 ,  B01L2200/027 ,  B01L2200/04 ,  B01L2200/0647 ,  B01L2200/141 ,  B01L2300/044 ,  B01L2300/0672 ,  B01L2300/0681 ,  B01L2300/0829 ,  B01L2300/0864 ,  B01L2300/0867 ,  B01L2300/0887 ,  B01L2300/089 ,  B01L2300/161 ,  B01L2400/0427 ,  B01L2400/043 ,  B01L2400/0478 ,  B01L2400/0683

Abstract: A liquid droplet manipulation system has a substrate with at least one electrode array and a central control unit for controlling selection of individual electrodes of the electrode array and for providing the electrodes with individual voltage pulses for manipulating liquid droplets by electrowetting. A working film is placed on top of the electrodes for manipulating samples in liquid droplets with the electrode array. At least one selected individual electrode of the electrode array is configured to be penetrated by light of an optical detection system for the optical inspection or analysis of samples in liquid droplets that are located on the working film. Also disclosed is working film that is to be placed on the electrode array and a cartridge that includes such a working film for manipulating samples in liquid droplets.

公开(公告)号：US09857332B2

公开(公告)日：2018-01-02

申请号：US13737360

申请日：2013-01-09

Applicant: Tecan Trading AG

Inventor： Travis Lee ,  Michael Benjamin Franklin ,  Kailiang Wang ,  Anne R. Kopf-Sill

IPC: G01N27/447 ,  B01L3/00 ,  B01L7/00

CPC classification number: G01N27/44791 ,  B01L3/502715 ,  B01L3/502738 ,  B01L3/502792 ,  B01L3/5029 ,  B01L3/523 ,  B01L3/527 ,  B01L7/52 ,  B01L2200/025 ,  B01L2200/027 ,  B01L2200/04 ,  B01L2200/0647 ,  B01L2200/141 ,  B01L2300/044 ,  B01L2300/0672 ,  B01L2300/0681 ,  B01L2300/0829 ,  B01L2300/0864 ,  B01L2300/0867 ,  B01L2300/0887 ,  B01L2300/089 ,  B01L2300/161 ,  B01L2400/0427 ,  B01L2400/043 ,  B01L2400/0478 ,  B01L2400/0683

Abstract: A liquid droplet manipulation system has a substrate with at least one electrode array and a central control unit for controlling selection of individual electrodes of the electrode array and for providing the electrodes with individual voltage pulses for manipulating liquid droplets by electrowetting. A working film is placed on top of the electrodes for manipulating samples in liquid droplets with the electrode array. At least one selected individual electrode of the electrode array is configured to be penetrated by light of an optical detection system for the optical inspection or analysis of samples in liquid droplets that are located on the working film. Also disclosed is working film that is to be placed on the electrode array and a cartridge that includes such a working film for manipulating samples in liquid droplets.

公开(公告)号：US11543383B2

公开(公告)日：2023-01-03

申请号：US15818428

申请日：2017-11-20

Applicant: TECAN TRADING AG

Inventor： Travis Lee ,  Michael Benjamin Franklin ,  Kailiang Wang ,  Anne R. Kopf-Sill

IPC: B01L3/00 ,  G01N27/447 ,  B01L7/00

Abstract: A liquid droplet manipulation system has a substrate with at least one electrode array and a central control unit for controlling selection of individual electrodes of the electrode array and for providing the electrodes with individual voltage pulses for manipulating liquid droplets by electrowetting. A working film is placed on top of the electrodes for manipulating samples in liquid droplets with the electrode array. At least one selected individual electrode of the electrode array is configured to be penetrated by light of an optical detection system for the optical inspection or analysis of samples in liquid droplets that are located on the working film. Also disclosed is working film that is to be placed on the electrode array and a cartridge that includes such a working film for manipulating samples in liquid droplets.

公开(公告)号：US20130126358A1

公开(公告)日：2013-05-23

申请号：US13737360

申请日：2013-01-09

Applicant: TECAN TRADING AG

Inventor： Travis Lee ,  Michael Benjamin Franklin ,  Kailiang Wang

IPC: G01N27/447

CPC classification number: G01N27/44791 ,  B01L3/502715 ,  B01L3/502738 ,  B01L3/502792 ,  B01L3/5029 ,  B01L3/523 ,  B01L3/527 ,  B01L7/52 ,  B01L2200/025 ,  B01L2200/027 ,  B01L2200/04 ,  B01L2200/0647 ,  B01L2200/141 ,  B01L2300/044 ,  B01L2300/0672 ,  B01L2300/0681 ,  B01L2300/0829 ,  B01L2300/0864 ,  B01L2300/0867 ,  B01L2300/0887 ,  B01L2300/089 ,  B01L2300/161 ,  B01L2400/0427 ,  B01L2400/043 ,  B01L2400/0478 ,  B01L2400/0683

Abstract: A liquid droplet manipulation system has a substrate with at least one electrode array and a central control unit for controlling selection of individual electrodes of the electrode array and for providing the electrodes with individual voltage pulses for manipulating liquid droplets by electrowetting. A working film is placed on top of the electrodes for manipulating samples in liquid droplets with the electrode array. At least one selected individual electrode of the electrode array is configured to be penetrated by light of an optical detection system for the optical inspection or analysis of samples in liquid droplets that are located on the working film. Also disclosed is working film that is to be placed on the electrode array and a cartridge that includes such a working film for manipulating samples in liquid droplets.

Abstract translation: 液滴操作系统具有具有至少一个电极阵列的基板和用于控制电极阵列的各个电极的选择的中央控制单元，并且用于通过电润湿来为电极提供用于操纵液滴的各个电压脉冲。 将工作薄膜放置在电极顶部，用电极阵列操纵液滴中的样品。 电极阵列的至少一个所选择的单独电极被配置为被光学检测系统的光穿透，用于光学检查或分析位于工作膜上的液滴中的样品。 还公开了将放置在电极阵列上的工作膜和包括用于操纵液滴中的样品的这种工作膜的盒。