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    New and improved method and apparatus for automatic baseline and standard calibration of automatic, multichannel sequentially operable fluid sample supply, treatment and analysis means
    1.
    发明授权
    New and improved method and apparatus for automatic baseline and standard calibration of automatic, multichannel sequentially operable fluid sample supply, treatment and analysis means 失效
    自动基线自动，多通道顺序可操作流体样品供应，处理和分析方法的新改进方法和装置

    公开(公告)号：US3634868A

    公开(公告)日：1972-01-11

    申请号：US3634868D

    申请日：1970-03-13

    Applicant: TECHNICON INSTR

    Inventor： PELAVIN MILTON H ,  KOSZYN ALLAN I ,  HEIER EARL

    IPC: G01N21/27 ,  G01N35/08 ,  G01N21/20

    CPC classification number: G01N21/274 ,  G01N35/08 ,  G01N2201/12723

    Abstract: New and improved method and apparatus for automatic, periodic baseline and standard calibration of analysis results recording means which record the results of sample analyses performed by multichannel sample analysis means in accordance with the output of the latter are provided to compensate for drift in said analysis means output, and comprise the conditioning of said sample analysis means and the adjustment of said output to a desired value for baseline calibration for each of said channels, the conditioning of said sample analysis means and the adjustment of said output to a desired value for standard calibration for each of said channels, the comparison of said output with said desired value thereof for baseline calibration for each of said channels and, if drift has occurred, the generation of information to drive said output to said desired value for baseline calibration, the comparison of said output with said desired value thereof for standard calibration for each of said channels and, if drift has occurred, the generation of information to drive said output to said desired value thereof for standard calibration, the storing of said baseline and standard calibration information for each of said channels for repeated reuse in sequence with channel changes during sample analysis operation of said sample analysis means, and the updating of said standard and baseline calibration information for each of said channels by the standard and baseline calibration information generated during subsequent operation of said calibration apparatus.

    Abstract translation: 提供新的和改进的用于分析结果的自动，周期性基线和标准校准的方法和装置，记录装置，其记录根据后者的输出的多通道样本分析装置进行的样本分析结果，以补偿所述分析装置中的漂移 输出，并且包括对所述样本分析装置的调节和将所述输出调节到用于每个所述通道的基线校准的期望值，所述样本分析装置的调节和所述输出的调节为用于标准校准的期望值 对于每个所述通道，将所述输出与所述期望值的比较用于每个所述通道的基线校准，并且如果发生漂移，则产生用于将所述输出驱动到所述基准校准所需值的信息， 所述输出具有所述期望值，用于每个所述cha的标准校准 并且如果发生漂移，则产生用于将所述输出驱动到所述期望值的信息以用于标准校准，存储所述基准线和每个所述信道的标准校准信息，以便在样本分析期间按顺序重新使用信道变化 所述样本分析装置的操作，以及通过在所述校准装置的后续操作期间产生的标准和基线校准信息来更新每个所述通道的所述标准和基线校准信息。

    Hematology apparatus
    9.
    发明授权
    Hematology apparatus 失效
    HEMATOLOGY APPARATUS

    公开(公告)号：US3427135A

    公开(公告)日：1969-02-11

    申请号：US3427135D

    申请日：1966-07-11

    Applicant: TECHNICON INSTR

    Inventor： PELAVIN MILTON H ,  WESCHLER WILLIAM A ,  NEGERSMITH KENT M

    IPC: G01N33/49 ,  A61B5/155 ,  G01N33/483 ,  G01N35/08 ,  G01N33/16 ,  G01N31/00

    CPC classification number: G01N35/085 ,  G01N2015/0073 ,  G01N2015/008 ,  G01N2015/1062 ,  G01N2015/1087 ,  G01N2015/1486 ,  Y10T436/118339

    Abstract: 1,192,192. Determining blood characteristics. TECHNICON CORP. 22 June, 1967 [11 July, 1966], No. 28851/67. Heading B1X. Apparatus for determining blood characteristics comprises supply means 12 for providing an initial stream of the samples to be tested; means 30, 32, 34, 36 coupled to junction 20 for providing a plurality of quotient streams, each containing a fractional portion of each of the samples in the initial stream; first treating means coupled to tube 34 for treating one quotient stream for HCT analysis, first determining means for measuring the HCT for example by continuous measurement of the resistance of the stream by means of electrodes 54 and for providing a signal responsive to the HCT measurement; second treating means for treating another of the quotient streams for analysis and second determining means for making the appropriate measurement and providing a signal responsive to it; and recording means 132 for receiving the signals and recording in correlation the signals obtained by measurements on the fractional portions of a common sample of the initial stream. The quotient stream in tube 30 may be twice diluted with saline (at junctions 58 and 76) then passed through phaser coil 80 (see 1,183,631) to counter module 84 for RBC determination. The quotient stream in tube 32 may be lysed with water added at 107, mixed with ferricyanide-cyanide reagent at 116 to convert the haemoglobin to cyanomethaemoglobin and passed through phaser coil 121 to colorimeter 130 for HGB measurement. The quotient stream in tube 36 may be lysed with acetic acid and a surfactant added at 96, and passed through phaser coil 104 to counter module 84 for WBC determination. MCH, MCV and MCHC are calculated from the measured characteristics and all seven characteristics of the sample are printed out on a single document (Fig. 3 not shown). The circuit (Fig. 2 not shown) permits display of the measured characteristics in turn on a meter.

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