公开(公告)号：US20240264194A1

公开(公告)日：2024-08-08

申请号：US18432494

申请日：2024-02-05

Applicant: Samsung Electronics Co., Ltd.

Inventor： Yeontae Kim ,  Jinhee Park ,  Joengseok Kim ,  Jinseop Lee ,  Bongkyun Jin ,  Eunju Park ,  Eungsun Lee ,  Hyekyoung Moon ,  Hyangbong Lee ,  Hyunyul Park ,  Seoungkyo Yoo

IPC: G01N35/10 ,  G01N33/18 ,  G01N35/08

CPC classification number: G01N35/1095 ,  G01N33/1813 ,  G01N35/085 ,  G01N35/1016

Abstract: Provided is a contaminant analysis apparatus including a pretreatment sampler configured to collect and filter an effluent discharged through a discharge pipe to provide an analysis target sample, a sample introduction unit configured to receive the analysis target sample from the pretreatment sampler, a sample injection unit configured to selectively supply the analysis target sample supplied from the sample introduction unit, a sample analysis unit including an integrated analyzer configured to analyze ion components and heavy metal components of the analysis target sample which is supplied from the sample injection unit, and an analysis controller configured to control the sample introduction unit, the sample injection unit, and the sample analysis unit, wherein the sample introduction unit includes a first sample introduction unit including two or more first sample introduction unit syringe pumps and a second sample introduction unit including one or more second sample introduction unit syringe pumps.

公开(公告)号：US12050231B2

公开(公告)日：2024-07-30

申请号：US17615893

申请日：2020-05-25

Applicant: Shimadzu Corporation

Inventor： Hiroshi Iwata ,  Hiroomi Goto ,  Shigehiko Zoda ,  Eiichi Ozeki ,  Takahiro Nishimoto ,  Aline Rotzetter ,  Yasuko Yoneda ,  Ippei Takeuchi

IPC: G01N35/08 ,  G02B21/36

CPC classification number: G01N35/085 ,  G02B21/365

Abstract: A testing method using a micro flow path device configured for a test liquid containing a specimen to be brought into contact with a drug therein and for a test on an action of the drug on the specimen includes: preparing the micro flow path device including: a plurality of micro flow paths, first and second openings which are disposed at both ends of each of the plurality of micro flow paths and communicate with an outside, a storage unit which is provided in each of the plurality of micro flow paths and stores the drug, and a gas-permeable membrane covering the first opening; applying a fluid pressure higher than an external pressure to the test liquid through the second opening from a syringe pump connected to the second opening to pressure-feed the test liquid to the storage unit; and observing a target region set in the micro flow path.

公开(公告)号：US12005454B2

公开(公告)日：2024-06-11

申请号：US17145858

申请日：2021-01-11

Applicant: 10X Genomics, Inc.

Inventor： Rajiv Bharadwaj ,  Kevin Ness ,  Debkishore Mitra ,  Donald A. Masquelier ,  Anthony Makarewicz ,  Christopher Hindson ,  Benjamin Hindson ,  Serge Saxonov

IPC: B01L3/00 ,  B01L3/02 ,  G01N35/00 ,  G01N35/08 ,  G01N35/10

CPC classification number: B01L3/502761 ,  B01L3/0241 ,  B01L3/502784 ,  B01L2200/0673 ,  B01L2300/0816 ,  B01L2400/049 ,  B01L2400/086 ,  G01N2035/00237 ,  G01N35/085 ,  G01N2035/1034

Abstract: The disclosure provides devices, systems and methods for the generation of encapsulated reagents and the partitioning of encapsulated reagents for use in subsequent analyses and/or processing, such as in the field of biological analyses and characterization.

公开(公告)号：US20190219045A1

公开(公告)日：2019-07-18

申请号：US16366258

申请日：2019-03-27

Applicant: SARTORIUS LAB INSTRUMENTS GMBH & CO. KG

Inventor： Jonas BODE ,  Malte STAENDER

IPC: F04B39/08 ,  F04B39/10

CPC classification number: F04B39/08 ,  A61M5/1408 ,  F04B39/10 ,  G01G17/04 ,  G01N35/085

Abstract: A distributor head for a suction pump which includes a housing (12), a pump port (16) configured to apply a negative pressure, and a plurality of hollow needles (18). The hollow needles are fixed to the housing (12), are connected in a liquid-tight manner to the pump port (16), and are arranged parallel to and at a distance from one another. Individual connecting paths (34) of the hollow needles (18) to the pump port (16) include respective, independently operable control valves (36).

公开(公告)号：US20180193838A1

公开(公告)日：2018-07-12

申请号：US15861225

申请日：2018-01-03

Applicant: The University of Chicago

Inventor： Rustem F. Ismagilov ,  Joshua David Tice ,  Helen Song Baca ,  Lewis Spencer Roach

IPC: B01L3/00 ,  C12Q1/44 ,  B01F3/08 ,  B01F5/06 ,  B01F13/00 ,  C12P19/34 ,  B01J19/00 ,  G01N15/14 ,  G01N35/08 ,  B01L7/00 ,  B82Y30/00

CPC classification number: B01L3/502784 ,  B01F3/0861 ,  B01F5/0403 ,  B01F5/0646 ,  B01F5/0647 ,  B01F13/0071 ,  B01F2215/0037 ,  B01J19/0046 ,  B01J19/0093 ,  B01J2219/00286 ,  B01J2219/00576 ,  B01J2219/00585 ,  B01J2219/0059 ,  B01J2219/00599 ,  B01J2219/00722 ,  B01J2219/00725 ,  B01J2219/00736 ,  B01J2219/0074 ,  B01J2219/00756 ,  B01J2219/00783 ,  B01J2219/00837 ,  B01J2219/0086 ,  B01J2219/00867 ,  B01J2219/00869 ,  B01J2219/00889 ,  B01J2219/00891 ,  B01J2219/00975 ,  B01J2219/00977 ,  B01L3/502746 ,  B01L3/502761 ,  B01L7/52 ,  B01L2200/0647 ,  B01L2200/0668 ,  B01L2200/0673 ,  B01L2200/10 ,  B01L2300/0867 ,  B01L2300/0883 ,  B01L2400/0424 ,  B01L2400/0448 ,  B01L2400/0454 ,  B01L2400/0487 ,  B82Y30/00 ,  C12P19/34 ,  C12Q1/44 ,  G01N15/1404 ,  G01N15/1484 ,  G01N35/08 ,  G01N35/085 ,  G01N2015/1409 ,  Y02A90/26 ,  Y10T436/118339 ,  Y10T436/12 ,  Y10T436/2575

Abstract: The present invention provides microfabricated substrates and methods of conducting reactions within these substrates. The reactions occur in plugs transported in the flow of a carrier-fluid.

公开(公告)号：US09968933B2

公开(公告)日：2018-05-15

申请号：US15673955

申请日：2017-08-10

Applicant: The University of Chicago

Inventor： Rustem F. Ismagilov ,  Joshua David Tice ,  Helen Song Baca ,  Lewis Spencer Roach

IPC: B01L3/00 ,  B01L7/00 ,  B01J19/00 ,  B01F3/08 ,  B01F5/06 ,  B01F13/00 ,  G01N15/10 ,  B01F5/04

CPC classification number: B01L3/502784 ,  B01F3/0861 ,  B01F5/0403 ,  B01F5/0646 ,  B01F5/0647 ,  B01F13/0071 ,  B01F2215/0037 ,  B01J19/0046 ,  B01J19/0093 ,  B01J2219/00286 ,  B01J2219/00576 ,  B01J2219/00585 ,  B01J2219/0059 ,  B01J2219/00599 ,  B01J2219/00722 ,  B01J2219/00725 ,  B01J2219/00736 ,  B01J2219/0074 ,  B01J2219/00756 ,  B01J2219/00783 ,  B01J2219/00837 ,  B01J2219/0086 ,  B01J2219/00867 ,  B01J2219/00869 ,  B01J2219/00889 ,  B01J2219/00891 ,  B01J2219/00975 ,  B01J2219/00977 ,  B01L3/502746 ,  B01L3/502761 ,  B01L7/52 ,  B01L2200/0647 ,  B01L2200/0668 ,  B01L2200/0673 ,  B01L2200/10 ,  B01L2300/0867 ,  B01L2300/0883 ,  B01L2400/0424 ,  B01L2400/0448 ,  B01L2400/0454 ,  B01L2400/0487 ,  B82Y30/00 ,  C12P19/34 ,  C12Q1/44 ,  G01N15/1404 ,  G01N15/1484 ,  G01N35/08 ,  G01N35/085 ,  G01N2015/1409 ,  Y02A90/26 ,  Y10T436/118339 ,  Y10T436/12 ,  Y10T436/2575

Abstract: The present invention provides microfabricated substrates and methods of conducting reactions within these substrates. The reactions occur in plugs transported in the flow of a carrier-fluid.

公开(公告)号：US20180008984A1

公开(公告)日：2018-01-11

申请号：US15687856

申请日：2017-08-28

Applicant: 10X Genomics, Inc.

Inventor： Rajiv Bharadwaj ,  Kevin Ness ,  Debkishore Mitra ,  Donald Masquelier ,  Anthony Makarewicz ,  Christopher Hindson ,  Benjamin Hindson ,  Serge Saxonov

IPC: B01L3/00 ,  B01L3/02 ,  G01N35/10 ,  G01N35/00 ,  G01N35/08

CPC classification number: B01L3/502761 ,  B01L3/0241 ,  B01L3/502784 ,  B01L2200/0673 ,  B01L2300/0816 ,  B01L2400/049 ,  B01L2400/086 ,  G01N35/085 ,  G01N2035/00237 ,  G01N2035/1034

Abstract: The disclosure provides devices, systems and methods for the generation of encapsulated reagents and the partitioning of encapsulated reagents for use in subsequent analyses and/or processing, such as in the field of biological analyses and characterization.

公开(公告)号：US09851347B2

公开(公告)日：2017-12-26

申请号：US14403845

申请日：2013-07-05

Applicant: Creoptix Ltd.

Inventor： Kaspar Cottier

IPC: G01N33/53 ,  G01N35/08

CPC classification number: G01N33/5302 ,  G01N35/085

Abstract: A flow conduit system (100, 200a, 200b) suitable for biochemical sensing, the flow conduit system (100, 200a, 200b) having a first flow cell conduit (1) with one or more sensing areas for biochemical sensing; a first selector valve (4); a first inlet/outlet conduit (2) which fluidly connects the first flow cell conduit (1) to the first selector valve (4); a first injection conduit (6) having a first end and a second end; a second injection conduit (7) having a first end and a second end; a fluid injecting means (8) fluidly connected to the second ends of each of the first and second injection conduits (6, 7) so that the fluid injecting means can selectively inject fluids into the first and/or second injection conduits (6,7); wherein the first injection conduit (6) is fluidly connected, at its first end, to the first inlet/outlet conduit (2) by a valveless junction (9), and the second injection conduits (6) is fluidly connected, at its first end, to the first inlet/outlet conduit (2) by a valveless junction (9).

公开(公告)号：US09839893B2

公开(公告)日：2017-12-12

申请号：US14836432

申请日：2015-08-26

Applicant: The University of Chicago

Inventor： Rustem F. Ismagilov ,  Joshua David Tice ,  Helen Song ,  Lewis Spencer Roach

IPC: B01L3/00 ,  B01J19/00 ,  B01F5/06 ,  B01F13/00 ,  G01N35/08 ,  C12P19/34 ,  C12Q1/44 ,  B82Y30/00 ,  G01N15/14

CPC classification number: B01L3/502784 ,  B01F3/0861 ,  B01F5/0403 ,  B01F5/0646 ,  B01F5/0647 ,  B01F13/0071 ,  B01F2215/0037 ,  B01J19/0046 ,  B01J19/0093 ,  B01J2219/00286 ,  B01J2219/00576 ,  B01J2219/00585 ,  B01J2219/0059 ,  B01J2219/00599 ,  B01J2219/00722 ,  B01J2219/00725 ,  B01J2219/00736 ,  B01J2219/0074 ,  B01J2219/00756 ,  B01J2219/00783 ,  B01J2219/00837 ,  B01J2219/0086 ,  B01J2219/00867 ,  B01J2219/00869 ,  B01J2219/00889 ,  B01J2219/00891 ,  B01J2219/00975 ,  B01J2219/00977 ,  B01L3/502746 ,  B01L3/502761 ,  B01L7/52 ,  B01L2200/0647 ,  B01L2200/0668 ,  B01L2200/0673 ,  B01L2200/10 ,  B01L2300/0867 ,  B01L2300/0883 ,  B01L2400/0424 ,  B01L2400/0448 ,  B01L2400/0454 ,  B01L2400/0487 ,  B82Y30/00 ,  C12P19/34 ,  C12Q1/44 ,  G01N15/1404 ,  G01N15/1484 ,  G01N35/08 ,  G01N35/085 ,  G01N2015/1409 ,  Y02A90/26 ,  Y10T436/118339 ,  Y10T436/12 ,  Y10T436/2575

Abstract: The present invention provides microfabricated substrates and methods of conducting reactions within these substrates. The reactions occur in plugs transported in the flow of a carrier-fluid.

公开(公告)号：US09731295B2

公开(公告)日：2017-08-15

申请号：US14402055

申请日：2013-05-17

Applicant: C2 DIAGNOSTICS

Inventor： Henri Champseix

IPC: G01N33/00 ,  B01L3/00 ,  G01N35/00 ,  G01N35/08 ,  G01N35/10

CPC classification number: B01L3/563 ,  B01L3/565 ,  G01N35/00029 ,  G01N35/085 ,  G01N35/1002 ,  G01N35/1095

Abstract: A fluid connection device is provided for biological analysis apparatuses, intended to simultaneously connect a plurality of fluid conduits and at least one fluidic component including a connecting surface with a plurality of fluid ports, the device having: (i) a holding plate, (ii) removable attachment structure capable of pressing the holding plate against the connecting surface, (iii) connectors suitable for being fixed to the ends of the fluid conduits and provided with a seal suitable for allowing a sealed connection to be made between the connectors and the fluid ports, holding plate including through-openings opposite the fluid ports and being shaped in such a way as to be able to receive the connectors in through-openings and to hold them pressed against the connecting surface. A biological analysis apparatus implementing the device is also provided.